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Frimley, UK, May 8, 2019 – Novartis today announced a new subgroup analysis of the Phase III EXPAND study of oral, once-daily siponimod (BAF312) in patients with secondary progressive multiple sclerosis (SPMS). The results show siponimod, the first and only oral drug to delay disability progression in SPMS patients, has significant functional benefit on cognitive processing speed (CPS), the cognitive function most frequently affected by MSi,ii,[iv]. The new findings, presented at the 2019 American Academy of Neurology Annual Meeting (AAN) in Philadelphia, Pennsylvania, USA, show that patients treated earlier in their disease course with less cognitive impairment benefited most from siponimod treatment vs. placeboi. This suggests that earlier treatment can lead to better cognitive outcomes,…
Healthcare Campaign  Executed Across 10 Countries to Raise Awareness of the Importance of Predicting  and Preventing Osteoporosis and Bone Fracture, Particularly in Post-Menopausal  Women Thousand Oaks, Calif. (May 6, 2019) – Amgen, together with local healthcare partners in 10 countries around the  world, set on May 5, 2019, a Guinness World Record title for the most  osteoporosis screenings for an osteoporosis campaign in 24 hours. To break the existing world  record, Amgen set out to screen at least a total of 3,000  people in 10 countries around the world -- to  help them understand their risk of having osteoporosis, a medical condition  that weakens bones and makes them more likely to fracture. The campaign took  place in Brazil, Canada, Colombia, Egypt, Kuwait, Lebanon, Mexico, Saudi…
Cambridge, 29th April 2019: The Xaar 1201 printhead is proving instrumental in helping Nottingham-based research organisation, Added Scientific, establish the suitability of inkjet printing in the manufacture of personalised pharmaceutical pills, where dosages could be tailored to individuals on an industrial scale. Building on research conducted by the University of Nottingham, where excipients (everything but the active pharmaceutical ingredient [API]) have been developed, Added Scientific initiated a project with its collaborators Xaar and AstraZeneca to look at the long-term scalability and suitability of inkjet printing in dispensing APIs. The project was funded under the Industrial Strategy Challenge Fund’s Medicines Manufacturing Challenge, with support from Innovate UK. “Inkjet pri…
Responding to Health Secretary Matt Hancock’s speech on the gender pay gap at the Royal College of Physicians annual conference, Danny Mortimer, chief executive of NHS Employers and NHS Confederation deputy chief executive, said:“There is urgent work to be done to address the gender pay gap. “Organisations in the NHS take seriously the need for them to address the underlying issues driving gender pay gaps across healthcare going forward.  “In September 2015 NHS Employers and the NHS Confederation launched the Health & Care Women Leaders Network to support women working across health and care. “The free network uses events, masterclasses and social media to share learning, celebrate skills and talents and connect colleagues to challenge gender stereotypes in the workplace and raise the…
London, UK – 23 April 2019: Ergomed plc, (LSE: ERGO) ('Ergomed' or the 'Company'), a company focused on providing specialised services to the pharmaceutical industry, today announces that PrimeVigilance, its pharmacovigilance, regulatory and medical information service provider, has been awarded the Queen’s Award for Enterprise for the second time reinforcing Ergomed’s broad leadership position as a provider of contract services. Now in its 53rd year, the Queen’s Awards for Enterprise are the most prestigious business awards in the country. Ergomed’s PrimeVigilance has received the 2019 Queen’s Award for International Trade in recognition of its year-on-year outstanding services in the drug safety sector for its global customer base. As an International Trade winner, PrimeVigilance has dem…
Pratteln, Switzerland, April 4, 2019 - Santhera Pharmaceuticals (SIX: SANN) announces that it has placed all of the remaining 500,000 registered shares from its existing authorized share capital in a private placement, resulting in aggregate gross proceeds of CHF 7.1 million. Taken together with the newly established credit line facility which, subject to certain conditions, amounts up to CHF 15.0 million, the proceeds of these near-term financing initiatives provide new liquid funds of up to CHF 22.1 million. Santhera has placed an aggregate of 500,000 registered shares with investors at a price of CHF 14.25 per share, representing a 4.5% discount to the closing price of today, raising gross proceeds of CHF 7.1 million. Santhera expects to issue the new shares during the coming days from…
Berkshire based PharmiWeb are excited to have launched a new version of of PharmiWeb.com - The new site, focusing on News, Events and Articles from the Pharma sector, brings together a wide range of content from multiple sources, to make the site an even better resource for the Pharma Industry.  Pharma Jobs  The hugely popular Job Board has moved to a new URL - PharmiWeb.Jobs. This means that for individuals looking for a the latest jobs in the pharma industry, PharmiWeb's new job board will the only place they need to go!  According to Portal Business Manager, Mike Wood - "This is the start of a very exciting growth stage for PharmiWeb, and we have a wide ranging plan of developments for the portal which will reinforce our position as one of the primary sources of global Pharma news. Our…
CeloNova BioSciences, Inc. (CeloNova), a global medical device company that offers a family of innovative products based upon its proprietary Polyzene™-F nanocoating technology, today announced that it has signed a three-year group purchasing agreement with HealthTrust for its novel COBRA PzF™ NanoCoated Coronary Stent (NCS) System. The agreement (contract number: 39949), which became effective on February 1, 2019, provides HealthTrust's more than 1,500 member hospitals and health systems with access to the world's first non drug-eluting, nanocoated coronary stent designed to help physicians safely and effectively treat patients who may benefit from short, 1-month minimum dual antiplatelet therapy (DAPT).1 DAPT has been shown to increase bleeding and mortality risks, which is of greater c…
*         ICARIA (Isatuximab in Combination with pomalidomide And low-dose dexamethasone veRsus pomalidomide and low dose dexamethasone in patients with refractory or relapsed And refractory Multiple Myeloma), study evaluated the benefit of isatuximab in combination with standard of care in prolonging progression free survival as compared to standard of care in patients with relapsed/refractory multiple myeloma *         Multiple myeloma is the second most common haematological cancer1 *         First randomised Phase 3 trial to evaluate the benefit of adding a monoclonal antibody to pomalidomide and dexamethasone for treatment of relapsed/refractory multiple myeloma I…
Merck, a leading science and technology company, and GSK, a science-led global healthcare company, today announced that the companies have entered into a global strategic alliance to jointly develop and commercialize M7824 (bintrafusp alfa*). M7824 is an investigational bifunctional fusion protein immunotherapy that is currently in clinical development, including potential registration studies, for multiple difficult-to-treat cancers. This includes a Phase II trial to investigate M7824 compared with pembrolizumab as a first-line treatment in patients with PD-L1 expressing advanced non-small cell lung cancer (NSCLC).   M7824 is designed to simultaneously target two immuno-suppressive pathways, transforming growth factor-β (TGF-β) trap and an anti-programmed cell death ligand-1 (PD-L1…
Torque, an immuno-oncology company developing first-in-class Deep Primed™ T Cell Therapeutics to direct immune power deep within the tumor microenvironment, and Thermo Fisher Scientific Inc. (NYSE: TMO), today announced a collaboration to build a dedicated Slipstream™ manufacturing facility for high-efficiency production of Torque's Deep-Primed T cell immunotherapies. Buildout of the Torque/Thermo Fisher manufacturing facility has begun, and the companies anticipate processing patient cells by the end of 2019. The Slipstream platform will initially be used in the clinical development of Torque's lead Deep-Primed T cell candidate, TRQ-1501, in solid and hematologic tumors; followed by TRQ-1201, also for solid and hematologic tumors. "Torque's cell manufacturing technology platform is crit…
Neuraxpharm Group, a leading European specialty pharmaceutical company focused on the treatment of central nervous system disorders (CNS), announces the acquisition of Farmax, a CNS specialty pharmaceutical company, from SVUS Pharma.   Farmax, located in Hradec Králové, Czech Republic, was the commercial division of SVUS Pharma, and has a strong distribution presence in the Czech Republic, Slovakia as well as a small presence in Hungary. Farmax is a leader in sales and marketing both branded and non-branded generics pharmaceuticals for CNS disorders such as Zolpinox®. It also commercializes well-known OTC nutraceuticals such as Preventan® and Maxicor®. Farmax has been renamed Neuraxpharm Bohemia and will commercialize its products under the Neuraxpharm brand. Leveraging its proprie…
The Janssen Pharmaceutical Companies of Johnson & Johnson today announced a worldwide collaboration and license agreement with MeiraGTx Holdings plc (NASDAQ: MGTX), a clinical-stage gene therapy company, to develop, manufacture and commercialize its clinical stage inherited retinal disease portfolio, including leading product candidates for achromatopsia (ACHM) caused by mutations in either CNGB3 or CNGA3, and X-linked retinitis pigmentosa (XLRP). Further, the companies have formed a research collaboration to explore new targets for other inherited retinal diseases and further develop adeno-associated virus (AAV) manufacturing technology. "Janssen is excited to expand our portfolio with the addition of innovative assets that have the potential to improve sight or prevent the progressi…
Beckman Coulter Life Sciences today announced its acquisition of Labcyte, a privately held, acoustic liquid handling company based in San Jose, California. Labcyte is best known for its Echo® acoustic droplet ejection technology, which uses sound waves to transfer tiny amounts of liquid with unequalled speed and accuracy. This technology—the centerpiece of Labcyte's Echo Liquid Handlers—enables walkaway convenience and integration capabilities. Labcyte technology enables faster and more cost-effective laboratory workflows in applications such as drug discovery and genomics. "Labcyte's unique product portfolio complements our existing liquid handling and laboratory automation business. It provides new opportunities to develop and enhance time-saving solutions for customer workflows,"…
UPMC Health Plan and AstraZeneca today announced the initiation of a pioneering value-based contract effective Jan.1, 2019 for UPMC for Life Medicare members who are prescribed BRILINTA® (ticagrelor), a medication used to lower a patient's chances of having another heart attack or dying from one in the 12 months following a heart attack. The goal of the contract is to align the incentives of the manufacturer, AstraZeneca, with UPMC Health Plan by connecting reimbursement for BRILINTA® to clinical outcomes in a real-world population. Specifically, reimbursement for the medication will be linked to cardiovascular outcomes for people treated with BRILINTA® following a recent hospitalization for heart attack or unstable angina. This value-based contract is groundbreaking in two way…
Purdue Pharma L.P. (“Purdue”) and Alivio Therapeutics today announced that they have entered into a partnership to advance one of Alivio’s product candidates through clinical development with an option exercisable by Purdue to collaborate on a limited number of additional compounds utilising Alivio’s inflammation-targeting technology. ALV-107 is a non-opioid treatment being developed for interstitial cystitis/bladder pain syndrome (IC/BPS).   Alivio will receive up to $14.75 million in upfront and near-term license exercise payments and is eligible to receive royalties on product sales and over $260 million in research and development milestones. Purdue also has an option to invest in Alivio’s next equity financing.   “This collaboration with Alivio is an important milestone…
United Therapeutics Corporation (Nasdaq: UTHR) today announced the closing of the transactions contemplated by its license agreement with Arena Pharmaceuticals, Inc. (Nasdaq: ARNA). Under the agreement, United Therapeutics acquired exclusive, worldwide rights to develop and manufacture the Phase 3 investigational drug candidate ralinepag, a next-generation, oral, selective and potent prostacyclin receptor agonist in development for the treatment of pulmonary arterial hypertension (PAH).  Upon closing, United Therapeutics paid Arena $800 million. Arena is also entitled to potential milestone payments of up to $400 million based on the achievement of certain regulatory events as well as low double-digit tiered royalties on annual net sales of ralinepag products.   &n…
Amgen (NASDAQ: AMGN) and Allergan plc. (NYSE: AGN) today announced positive top-line results from a Phase 1/ Phase 3 study evaluating the pharmacokinetics, efficacy and safety of biosimilar candidate ABP 798, a biosimilar candidate to RITUXAN® (rituximab), compared to rituximab in patients with moderate-to-severe rheumatoid arthritis. The results demonstrate that the study met its primary endpoint of pharmacokinetic (PK) similarity. Additionally, equivalent efficacy was established and a similar safety profile was demonstrated. The primary objective of the study was PK similarity comparing ABP 798 to rituximab. The PK endpoints of the study were area under the serum concentration–time curve (AUC) and maximum serum concentration (Cmax), both of which were within the pre-specified equi…
B-MoGen Biotechnologies, Inc. and CytoSen Therapeutics announced today a research collaboration to develop the next generation of gene-modified Natural Killer Cell (NK) therapies.  B-MoGen will utilize its expertise in genetic design and its patented non-viral gene delivery platform in conjunction with CytoSen's nanoparticle expansion platform to improve efficacy and reduce cost of NK cell therapeutics.  "We are very excited and look forward to teaming up with CytoSen to utilize our scientific expertise and engineering work with CARs and TCRs to help develop NK treatments in the human therapeutics space," said Jeff Liter, President and CEO of B-MoGen.  "CytoSen's innovation, science and pioneering technology is a perfect fit with B-MoGen's genome engineering experience and…
LunaPBC, founder of LunaDNA, the first community-owned genomic and health data platform, announced today its partnership with Genetic Alliance, a non-profit dedicated to providing ordinary people with powerful tools to transform research. Over the course of 2019, the organizations will merge Genetic Alliance's Platform for Engaging Everyone Responsibly engagement platform with LunaDNA to provide individuals and communities with more resources to support health management while maximizing research opportunities. The partnership enables LunaPBC and Genetic Alliance to unite their shared mission and technologies to create seamless solutions to support individuals, disease foundations, and patient advocacy organizations while also powering disease research at scale. Shared values across…