Today Stories

Sumitomo Dainippon Pharma Co., Ltd. (Head Office: Osaka, Japan; President: Masayo Tada; hereinafter "Sumitomo Dainippon Pharma") and Angelini S.p.A. (Head Office: Rome, Italy; CEO: Gianluigi Frozzi; hereinafter "Angelini") announced today that the companies have formed a partnership (entering into a license and distribution agreement) with the goal to expand availability in Europe of Latuda® (generic name: lurasidone hydrochloride; hereinafter "LATUDA"), an atypical antipsychotic which was created by Sumitomo Dainippon Pharma. Under the terms of the agreement, Sunovion Pharmaceuticals Europe Ltd., a subsidiary company of Sumitomo Dainippon Pharma Group, (hereinafter "Sunovion Europe") has granted Angelini exclusive commercialization rights for LATUDA in 29 European countries[*] and in Tur…

WuXi AppTec (WuXi), a leading global pharmaceutical, biotechnology and medical device open-access capability and technology platform company, announced that its Advanced Therapy Unit based in Philadelphia has been selected as a manufacturing partner for advanced therapies through the California Institute for Regenerative Medicine (CIRM) funded IQVIA (formerly QuintilesIMS) Stem Cell Center. In collaboration with its partners, the Stem Cell Center aims to accelerate the preclinical/clinical development, and commercialization of stem cell, cellular and gene-modified therapies via end-to-end solutions and targeted services to advance assets from candidate identification through market authorization and improve the probability of clinical and commercial success. WuXi AppTec Advanced Ther…

The Advisory Board Company (NASDAQ: ABCO) and Optum announced that, at a special meeting of Advisory Board stockholders held today, stockholders holding a majority of the outstanding shares of the company's common stock voted to approve the adoption of the previously disclosed merger agreement with Optum. Pursuant to the agreement, Optum will acquire Advisory Board through a merger and, as previously disclosed, Advisory Board will sell its education business to affiliates of Vista Equity Partners prior to the closing of the merger, which is expected to be completed Friday, November 17, 2017. The agreement combines The Advisory Board Company's industry-leading independent research, strategic health care advisory services, and strong capabilities in analytics with Optum's complementary pro…

Diplomat Pharmacy, Inc. (NYSE: DPLO), has entered into a definitive agreement to acquire Leehar Distributors, LLC, doing business as LDI Integrated Pharmacy Services (LDI), from investment firms Nautic Partners, LLC and Oak HC/FT Partners LLC, and management. The transaction is expected to close in 30–60 days. Diplomat will discuss its acquisition on a conference call at 5 p.m. ET Wednesday, Nov. 15. Listen to a live broadcast by calling 833.286.5805 (647.689.4450 for international callers) and using participant code 1788088. A recording of the conference call will be available for approximately 90 days on the investor relations section of Diplomat's website at ir.diplomat.is. LDI Integrated Pharmacy Services is a full-service pharmacy benefit manager (PBM) based in St. Louis, Missouri.…

Cardinal Health (NYSE: CAH) today announced that it has signed a definitive agreement to sell its Cardinal Health China business to Shanghai Pharmaceuticals Holding Co., Ltd. ("Shanghai Pharma") for $1.2 billion. The transaction is expected to close by the end of Cardinal Health's fiscal year, subject to closing conditions and regulatory clearances. The sale includes Cardinal Health's pharmaceutical and medical products distribution business in China. Cardinal Health expects that employees, infrastructure and various systems and processes that support this business will move to Shanghai Pharma upon closing of the transaction. The divestiture does not include Cardinal Health's remaining businesses in China, including Cordis, its recently acquired Patient Recovery business, its medical sour…

Focus on education and awareness-raising initiatives to facilitate prevention of type 2 diabetes Partnership activities include online course for healthcare professionals and joint awareness campaign on World Diabetes Day  14 November 2017   Merck, a leading science and technology company with 60 years of clinical experience in diabetes, today announced its partnership with the International Diabetes Federation (IDF) to implement education and communications activities emphasizing the importance of preventing type 2 diabetes. The IDF recognize diabetes overall as one of the largest global health emergencies of the 21st century and type 2 diabetes is the most common form of diabetes, estimated to contribute to up to 90% of global diabetes cases.1 Yet many cases of type 2 diabete…

ERS Genomics Ltd. and Cellecta, Inc. announced today a non-exclusive license agreement to provide Cellecta with worldwide access to ERS Genomics' CRISPR/Cas9 genome editing intellectual property for use in informing research tools and services. ERS Genomics holds rights to the foundational CRISPR/Cas9 patent portfolio from Dr. Emmanuelle Charpentier, who along with Dr. Jennifer Doudna at the University of California, Berkeley, adapted the CRISPR system into a breakthrough gene editing technology.    Cellecta is the first commercial provider of a lentiviral-based CRISPR library targeting all 19,000+ human protein-coding genes, and an industry leader in RNAi and CRISPR technologies for the discovery and characterization of novel therapeutic targets. Its off-the-shelf and custom ge…

Alcami, a leading provider of custom end-to-end development and manufacturing services for the pharmaceutical and biotechnology industries, today announces it has finalized manufacturing and quality agreements with Solasia Pharma, K.K. (TSE: 4597) for the clinical supply manufacture of the active pharmaceutical ingredient (API) darinaparsin, a novel mitochondrial-targeted agent developed for the treatment of various hematologic and solid cancers. Solasia is a Japan-based specialty pharmaceutical company dedicated to the development of innovative oncology medicines. In March 2011, Solasia acquired the rights to darinaparsin from ZIOPHARM Oncology, Inc. for the potential treatment of Peripheral T-Cell Lymphoma (PTCL). The agent is currently in Phase II pivotal trials in Asia. "We are pleas…

Health education startup MedCircle today announced a partnership with the accrediting organization Annenberg Center for Health Sciences at the Eisenhower to offer Annenberg CME/CE learners a new digital networking platform that facilitates greater engagement between healthcare providers and patients, family members and others interested in a specific health topic. "MedCircle was created to give those seeking information on health topics a way to tap into content they can trust," said Dr. Kapil Gupta, chief executive officer and founder of MedCircle. "With our partnership with the Annenberg Center, we provide an easy, secure way for Annenberg clinician-learners and other credentialed healthcare providers to engage with patients, patient advocates and interested consumers." The Annenberg C…

EpiSwitch™ technology to identify new targets and biomarkers relating to fibrotic mechanisms   Fibrosis associated with chronic inflammation is a serious unmet clinical need   Oxford BioDynamics Plc (AIM: OBD), a biotechnology company focused on the discovery and development of epigenetic biomarkers based on regulatory genome architecture, for use within the pharmaceutical and biotechnology industry, is pleased to announce that it has entered into an initial collaboration with a major US biopharmaceutical company to advance the discovery and development of novel treatments to address patients with abnormal wound healing response, leading to fibrosis. Fibrosis is a pathological feature of most chronic inflammatory diseases, which can affect nearly every tissue in the body. If…

Diplomat Pharmacy, Inc. (NYSE: DPLO), has entered into a definitive agreement to acquire Pharmaceutical Technologies, Inc., doing business as National Pharmaceutical Services. The transaction is expected to close in 30 days. National Pharmaceutical Services (NPS) is a full-service pharmacy benefit manager (PBM) based in Omaha, Nebraska. It features a proprietary claims-processing system and offers mail-order service under its Integrated HMO Pharmacy. "Industry dynamics and the evolution of our payor strategy have accelerated our push to add PBM-like services," said Phil Hagerman, CEO and chairman of Diplomat. Hagerman said small and midsize payors, self-funded employers, and unions are seeking flexible solutions to improve health care outcomes and reduce costs. Partnering with NPS, he s…

Ionis Pharmaceuticals, Inc. (NASDAQ: IONS) announced today that the company submitted a marketing authorization application (MAA) to the European Medicines Agency (EMA) for inotersen, based on the phase 3 NEURO-TTR study in patients with hereditary TTR amyloidosis (hATTR). The MAA for inotersen will be reviewed under the EMA's Accelerated Assessment program, which is intended to expedite access to drugs that the EMA considers to be of major therapeutic interest. "The submission of the inotersen MAA to the EMA represents a critical milestone for Ionis and for European patients suffering from ATTR. We are pleased that we met the last deadline for Accelerated Assessment in the EU for 2017. Next week, we also plan to submit the NDA to the FDA. Today's submission to the EMA puts us one step cl…

Amgen (NASDAQ: AMGN) and Novartis today announced an expanded collaboration with the Banner Alzheimer's Institute (BAI) to initiate a new trial – the Alzheimer's Prevention Initiative (API) Generation Study 2. This trial follows the launch of the Generation Study 1, and will determine whether the BACE1 inhibitor CNP520 can prevent or delay the onset of Alzheimer's disease symptoms in a high-risk population. BACE1 is an enzyme that plays an important role in the production of Amyloid β, a protein which accumulates in the brains of individuals with Alzheimer's disease years before clinical symptoms begin. More information on the sites participating in Generation Study 2 can be found at ClinicalTrials.gov and in the website www.GenerationProgram.com. "As a leader in the challenging fight to…

Almac Group, the global contract development and manufacturing organisation, today announced the acquisition of 100% shares of BioClin Laboratories, an independent and privately owned organisation based in Athlone, Ireland. Established in 2002 and located in Garrycastle, just two hours away from Almac Group’s Headquarters in Northern Ireland, BioClin is internationally recognised for providing expert analytical services including cGMP pharmaceutical and biopharmaceutical analysis, GMP microbiology testing and GLP bioanalysis. The company also boasts Ireland’s leading GLP certified (INAB), cGMP certified (HPRA) and FDA registered contract laboratory. BioClin’s bespoke 14,000sq ft modern facility significantly increases Almac’s analytical capacity and perfectly complements its ex…

Novartis announced today, that it has entered a memorandum of understanding with Advanced Accelerator Applications (AAA) under which Novartis intends to commence a tender offer for 100% of the share capital of AAA subject to certain conditions. Advanced Accelerator Applications (NASDAQ:AAAP) is a radiopharmaceutical company that develops, produces and commercializes Molecular Nuclear Medicines including Lutathera® (177Lu-DOTATATE), a first-in-class RLT product for neuroendocrine tumors (NETs). Radiopharmaceuticals, such as Lutathera, are unique medicinal formulations containing radioisotopes which are used clinically for both diagnosis and therapy. The transaction would strengthen Novartis' oncology presence with both near-term product launches as well as a new technology platform with pot…

Lannett Company, Inc. (NYSE: LCI) today announced that it has entered into a settlement and license agreement with Celgene Corporation that resolves patent infringement litigation in the U.S. related to Celgene's Thalomid®.  The license agreement permits Lannett to manufacture and market in the U.S. its generic thalidomide product as of August 1, 2019 or earlier under certain circumstances.  As mandated by the U.S. Food and Drug Administration (FDA), Thalomid® is subject to Risk Evaluation and Mitigation Strategies (REMS) program, which is designed and implemented during the commercialization of a pharmaceutical product to ensure an acceptable risk-to-benefit ratio for products that are known to exhibit specific risks. "I congratulate my staff and colleagues for showing the cour…

Tokyo, Japan, Basking Ridge, NJ, and Berlin, Germany – (October 30, 2017) – Daiichi Sankyo Company, Limited (hereafter, Daiichi Sankyo) and Glycotope GmbH (hereafter, Glycotope) have signed an option agreement for future strategic collaboration and licensing to develop an antibody drug conjugate (ADC) by combining Daiichi Sankyo’s proprietary ADC technology with Glycotope’s investigational tumor-associated TA-MUC1 antibody PankoMab-GEX®.   Under the terms of the agreement, once a feasibility study has been successfully completed, Daiichi Sankyo has the right to exercise its option for worldwide exclusive rights to develop and commercialize PankoMab-GEX ADC. If Daiichi Sankyo exercises these rights, Glycotope will receive an upfront payment as well as development and sales milestone…

ICON plc, (NASDAQ: ICLR) a global provider of drug development solutions and services to the pharmaceutical, biotechnology and medical device industries, and the International Consortium for Health Outcomes Measurement (ICHOM), a non-profit organization with the mission of driving value based health care, shared the findings of a global patient outcomes benchmarking platform at this week’s ICHOM’s annual conference in Washington DC. The platform aims to catalyse physician driven learning and improvement of the outcomes that matter most to patients. ICON and ICHOM first partnered to advance value-based healthcare through the launch of a global healthcare outcomes benchmarking pilot program called GLOBE in March 2016.  The pioneering work of the GLOBE pilot program, through its collab…

Omnicell, Inc. (NASDAQ: OMCL) today announced that Hackensack Meridian Health has chosen the Company's automated medication management solutions and enterprise services to serve the health care network's pharmacy needs. Hackensack Meridian Health serves New Jersey residents spanning from Bergen to Atlantic counties through its 13 hospitals and more than 140 ambulatory care centers, fitness and wellness centers, home health services, rehabilitation centers, and skilled nursing centers. Hackensack Meridian Health recognizes that having cohesive medication management technology across its healthcare system can play an integral role in improving clinical operations, specifically by promoting patient safety, supply chain efficiencies, and overall standardization efforts. As a nationally accred…

Microsoft and PAREXEL form cloud technology alliance aimed at accelerating the pace of drug development Companies seek to drive digital transformation of the biopharmaceutical industry by combining PAREXEL’s drug development expertise with Microsoft Azure. REDMOND, Wash., and BOSTON — Oct. 24, 2017 — Microsoft Corp. and PAREXEL International Corp., a leading global biopharmaceutical services organization, on Tuesday announced a technology development alliance aimed at driving innovation across the life sciences industry with technology powered by Microsoft Azure. The collaboration between Microsoft and PAREXEL is designed to help the industry accelerate drug development and bring new therapies to patients sooner. The companies will combine Microsoft’s global cloud infrastructure, intell…