Articles

Pathology is being transformed by digital technologies, artificial intelligence and advances in precision medicine. These innovations address many of the field’s most pressing challenges, including a global shortage of pathologists, rising cancer cases, and the critical need for faster, more accurate diagnostics.  
Companion diagnostics support the shift toward precision medicine by using biomarker analysis to match patients to the most effective treatments.  Recent advances in computational pathology have streamlined workflows for review of key CDx assays for biomarkers like HER2 and PD-L1 while simultaneously improving accuracy and reproducibility.  In the coming years, multiplex assays, capable of analyzing multiple biomarkers simultaneously, are poised to optimize selection of…

Typically, when organisations speak of supply chain transparency, they focus on the last mile: the product journey from “production to fork”, with a view to reducing energy and waste while optimising efficiency and flexibility in final delivery. However, the first mile of the supply chain – from “farm to production” – is just as important.
Typically, when organisations speak of supply chain transparency, they focus on the last mile: the product journey from “production to fork”, with a view to reducing energy and waste while optimising efficiency and flexibility in final delivery. However, the first mile of the supply chain – from “farm to production” – is just as important. The first mile encompasses everything before goods are received for manufacturing an end product, including raw mate…

Today, advancements in biotechnology have expanded the applications of S. cerevisiae beyond traditional practices, making it a powerhouse in the fields of food production, biofuel generation, and pharmaceutical manufacturing.
Saccharomyces cerevisiae, commonly known as baker's or brewer's yeast, is one of the most studied microorganisms in the realm of fermentation technology. This species of yeast has been utilized for thousands of years in various fermentation processes, including baking, brewing, and winemaking.    Historical Context cerevisiae has a rich history, dating back to ancient civilizations that used it in the production of bread and alcoholic beverages. Its ability to ferment sugars into ethanol and carbon dioxide made it indispensable for these processes. The yeast…

Broughton, a leading analytical testing and consultancy firm, highlights its commitment to sustainability in laboratory operations by promoting environmentally responsible practices, ethical governance, and proactive maintenance strategies. These efforts aim to reduce the environmental impact of laboratory operations while fostering a culture of innovation and accountability.
    Advancing sustainability in laboratory operations~ Driving environmental conservation through responsibility, collaboration, and innovation ~   Broughton, a leading analytical testing and consultancy firm, highlights its commitment to sustainability in laboratory operations by promoting environmentally responsible practices, ethical governance, and proactive maintenance strategies. These efforts aim…

The use of magnetic beads as a new DNA extraction tool shows numerous benefits compared to traditional extraction methods. The large specific surface area of magnetic beads makes them effective at adsorbing DNA molecules. Their ease of operation and automation leads to more accurate DNA extraction and reduced human error while conserving reagents.
Many fields including biomedical research, forensics, and environmental monitoring rely on DNA extraction as a crucial process. DNA extraction marks the essential beginning of genetic information collection and supports further experiments including genetic analysis disease diagnosis and species identification. Medical professionals perform genetic testing to diagnose genetic diseases through the extraction of DNA from patient samples while forens…

Agar is widely used in the food industry, pharmaceutical industry, bioengineering and other fields. It has coagulation and stability and is often used as a thickener, coagulant, suspending agent, emulsifier, stabilizer and preservative.
Agar is a natural polysaccharide extracted from red algae, primarily species of the genera Gelidium and Gracilaria. Agar is composed of two primary components: agarose and agaropectin. It is widely used in the food industry, pharmaceutical industry, bioengineering and other fields. It has coagulation and stability and is often used as a thickener, coagulant, suspending agent, emulsifier, stabilizer and preservative. Applications of Agar Microbiology Culture Media: Agar is a common culture media that is used to grow microbes. The gelling nature of the mate…

Selling medical devices to hospitals can be a lucrative yet challenging endeavor. With the healthcare industry growing and the demand for medical devices and medical equipment increasing, understanding how to sell medical devices effectively is crucial. In this guide, we’ll share key strategies for selling medical devices to hospitals, from identifying high-value facilities to proving your knowledge of their needs. Whether you’re selling medical equipment online or engaging with doctors and hospitals directly, these tips will help you navigate the complexities of the healthcare market.
  Selling medical devices to hospitals can be a lucrative yet challenging endeavor. With the healthcare industry growing and the demand for medical devices and medical equipment increasing, unde…

• Asian men’s statistically lower risk of prostate cancer is exaggerated by underreporting caused by stigma, according to a study in Cancers. • Cultural hesitancy around MRI scans, rectal examinations and biopsies is contributing to underdiagnosis. • A “transformative” next generation blood test can avoid these invasive procedures and detect prostate cancer more reliably and precisely. • EpiSwitch PSE has superior accuracy and fewer false positives than MRI scans and other commercially available blood tests. • EpiSwitch PSE reduces the false positive rate of the PSA test that the NHS routinely uses from 3 in 4 to less than 1 in 10. • The world leading innovation was seeded at Oxford University and developed with Imperial College NHS Trust. • In the US, it is reimbursed by Medicare; in the UK it is available privately, including from Bupa and at The London Clinic.

The nuclear medicine market is rapidly growing, driven by rising cases of cancer and heart disease, along with advancements in SPECT and PET imaging. Valued at $12.2B in 2024, it's expected to reach $29.8B by 2033 at a 10.39% CAGR. Major applications include cardiology, neurology, and oncology, with North America leading the market, while Asia-Pacific sees rapid growth. Key players like GE Healthcare, Bayer, and Novartis focus on innovation. Despite challenges like high costs and regulations, expanding healthcare investments and new radiopharmaceuticals present huge opportunities for future growth.
The global nuclear medicine market is expanding rapidly, thanks to advances in diagnostic imaging and targeted treatments. With the rise in chronic diseases like cancer and heart conditions,…

With the pharmaceutical sector so deeply interconnected with vendors, suppliers and distributors, it faces a broad expanse of third-party cybersecurity risks. To bolster cybersecurity resilience, pharmaceutical companies should establish a robust third-party risk management program, implement strict cybersecurity and compliance requirements in vendor contracts, enforce multi-layered security controls for third-party access, and more.
Cybercriminals’ tactics have evolved to target sensitive data and disrupt research and development in the pharmaceutical ecosystem through a highly effective hub-and-spoke strategy. This new method has attackers compromising a single common vendor — the hub — to access numerous pharma companies — the spokes. Why go for individual companies when you can simply…

Biomarkers are revolutionizing disease diagnosis and treatment by enabling early detection and personalized medicine. The market, valued at $272 million in 2024, is projected to reach $446 million by 2033, growing at 5.65% annually. Key drivers include advancements in genomics, AI, and precision medicine, while challenges like high costs and strict regulations slow progress. Leading companies like Roche and Thermo Fisher are investing heavily in biomarker research. As technology evolves, biomarkers will play a crucial role in making healthcare more precise and effective. 🚀
The use of biomarkers in medicine is transforming the way we detect diseases and develop treatments. Biomarkers are biological indicators—like proteins, genes, or molecules—that help doctors diagnose conditions earl…

Opioids are commonly prescribed to manage pain, but their effects on movement and coordination can pose serious risks, particularly for older adults. One major concern is their impact on gait. Changes in balance, muscle control, and reaction time can make walking unsteady, increasing the risk likelihood of dangerous falls. So, how do opioids increase the risk of falls in older adults?
Opioids are commonly prescribed to manage pain, but their effects on movement and coordination can pose serious risks, particularly for older adults. One major concern is their impact on gait. Changes in balance, muscle control, and reaction time can make walking unsteady, increasing the risk likelihood of dangerous falls. So, how do opioids increase the risk of falls in older adults? Understanding Opioids and…

Monitoring the safety of medical devices and pharmaceuticals after they enter the market is an essential responsibility for manufacturers. While the core purpose of Post Market Surveillance (PMS) is to protect patients, a well-implemented PMS strategy can also offer businesses substantial benefits. From refining product designs to streamlining regulatory compliance and even enhancing sustainability initiatives, PMS can be a transformative tool rather than merely a compliance obligation.
Monitoring the safety of medical devices and pharmaceuticals after they enter the market is an essential responsibility for manufacturers. While the core purpose of Post Market Surveillance (PMS) is to protect patients, a well-implemented PMS strategy can also offer businesses substantial benefits. From refi…

The medical equipment maintenance market is rapidly growing, driven by advanced technology, preventive maintenance, and increased healthcare spending. According to FutureWise analysis, the market was valued at US$ 48.8 billion in 2023 and is expected to reach US$ 111.01 billion by 2031, growing at a CAGR of 10.82%. Regular maintenance ensures patient safety, reduces downtime, and meets regulatory standards. Challenges include high costs, budget constraints, and environmental concerns. The future looks promising with AI-driven predictive maintenance and independent service providers. North America leads, while Asia-Pacific is the fastest-growing market.
Medical equipment plays a crucial role in hospitals and clinics. To ensure these devices work properly, regular maintenance is essential. Wi…

Though less abundant than other essential oils, α-Copaene's multifaceted applications across various sectors underscore its significance in areas ranging from perfumery to pest control.
Introduction α-Copaene is a naturally occurring sesquiterpene hydrocarbon widely recognized for its presence in essential oils, particularly those derived from plants like Copaiba balsam, cloves, and basil. Though less abundant than other essential oils, α-Copaene's multifaceted applications across various sectors underscore its significance in areas ranging from perfumery to pest control. Applications in Perfumery and Cosmetics One of the primary uses of α-Copaene is in the fragrance industry. Due to its warm and woody aroma, it serves as an attractive note in perfumes and scented products. The compoun…

Isopropanol, also known as isopropyl alcohol (IPA), is a versatile chemical compound widely used across an array of industries due to its unique chemical properties.
Isopropanol, also known as isopropyl alcohol (IPA), is a versatile chemical compound widely used across an array of industries due to its unique chemical properties. Recognized as a secondary alcohol with the molecular formula C3H8O, isopropanol is a colorless liquid, characterized by a distinct odor and high volatility. Its ability to mix fully with water, ethanol, and chloroform underscores its utility as a solvent for both polar and non-polar substances, making it a cornerstone in many industrial, pharmaceutical, and consumer product applications. Production Methods Isopropanol is primarily produced through two industrial me…

Bromopride, marketed as bromopyridine, is a well-known antiemetic and prokinetic drug widely utilized for its efficacy in treating nausea and vomiting.
Bromopride, marketed as bromopyridine, is a well-known antiemetic and prokinetic drug widely utilized for its efficacy in treating nausea and vomiting. As a dopamine antagonist, bromopride functions by binding to D2 receptors located in both the gastrointestinal tract and the central nervous system. This unique capability allows it to act effectively against gastrointestinal disorders and postoperative nausea. Mechanism of Action Bromopride's effectiveness is largely attributed to its dual action in inhibiting dopamine receptors. In the gastrointestinal system, it prevents dopamine activity, leading to less gastric relaxation and accele…

Medicinal plant extracts are derived from various parts of plants, including roots, stems, leaves, flowers, and fruits. These extracts contain bioactive compounds that are responsible for specific pharmacological effects.
In today's fast-paced world, where synthetic medications are often the go-to for treating ailments, there's a resurgent interest in the power of nature. Medicinal plant extracts, with their rich history and diverse applications, are at the forefront of this natural renaissance, showcasing numerous health benefits that blend seamlessly with both modern and traditional medical practices. Understanding Medicinal Plant Extracts Medicinal plant extracts are derived from various parts of plants, including roots, stems, leaves, flowers, and fruits. These extracts contain bioactiv…

This article delves into the defining characteristics and amplified functionalities of ASMPs due to amino functionalization, and their widespread applications.
Amino superparamagnetic microparticles (ASMPs) are a fascinating category of nanomaterials that interweave the magnetic allure of superparamagnetic particles with the adaptable nature of amino groups. This combination lends them a versatile edge, making them pivotal across sectors like biotechnology, environmental technology, and energy solutions. This article delves into the defining characteristics and amplified functionalities of ASMPs due to amino functionalization, and their widespread applications. Understanding Amino Superparamagnetic Microparticles ASMPs are unique due to their inherent superparamagnetic capabilities com…

The PD-1 and PD-L1 inhibitors market is growing rapidly due to rising cancer cases and advancements in immunotherapy. These inhibitors help the immune system recognize and attack tumors by blocking immune checkpoints. Key drugs include Nivolumab, Pembrolizumab, and Atezolizumab. The market was valued at $41.83 billion in 2023 and is expected to reach $178.58 billion by 2032. Growth is driven by expanding treatment approvals, combination therapies, and regulatory support. Challenges include high costs and increasing competition. Recent innovations, like Ivonescimab outperforming Keytruda, highlight ongoing advancements in the field.
Introduction Programmed cell death protein 1 (PD-1) and its ligand, PD-L1, are crucial immune checkpoints that regulate the body's immune response. While they he…