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Supporting the NHS on its decade-long journey towards an integrated health and care system, as well as delivering extra investment for new buildings and infrastructure, social care and addressing major gaps in NHS staffing, should be at the top of the new Prime Minister’s priority list. That is the call today from the NHS Confederation in a letter and briefing to the Prime Minister. The NHS Confederation, which represents organisations across the healthcare sector, says there is much ‘unfinished business’ for the new government to resolve in the health and care sector. The letter warns the Prime Minister that the question of NHS funding is not yet settled, despite the £20.5bn funding settlement that kicked in from April this year. The settlement excluded some vital areas of expenditure tha…
GlaxoSmithKline plc (GSK) today announced that Jonathan Symonds will succeed Sir Philip Hampton as Non-Executive Chairman of the GSK Board with effect from 1st September 2019. Jonathan is currently Deputy Group Chairman of HSBC Holdings plc and has been an independent non-executive Director of HSBC since April 2014. He is a former Chief Financial Officer of Novartis AG and AstraZeneca plc, and has been a non-executive Director of Diageo plc and QinetiQ plc. He is currently non-executive Chairman of Proteus Digital Health Inc, a non-executive director of Rubius Therapeutics Inc and Chairman of Genomics England Limited. The appointment was approved by the Board and follows a thorough succession process undertaken by the Nominations Committee, led by Vindi Banga, the company’s Senior Independ…
NEW YORK, July 22, 2019 (Newswire.com) - ​​​​​InvestAcure, PBC, honored 10 leading bioindustry scientists with the Cure Coin Award for their outstanding work developing groundbreaking scientific discoveries into lifesaving therapeutics for Alzheimer's, CTE and other related Dementias. The award reception took place on July 15, during the 2019 Alzheimer's Association International Conference in Los Angeles.  "The Cure Coin Award aims to bring public attention to the vital work of leading industry scientists developing lifesaving treatments," said Max Tokarsky, the founder and CEO of InvestAcure, a Public Benefit, Finance company building a spare-change investment platform to facilitate public investment in companies working on developing effective therapeutics for Alzheimer’s.  While govern…
Converse Pharma Group is primed for national expansion after securing a £60m combined facility from Royal Bank of Scotland (RBS) and Secure Trust Bank Commercial Finance. Founded in 2013, the firm is a national pharmaceutical wholesaler, providing a comprehensive range of prescription drugs to over 5,500 independent pharmacies across the UK and Ireland. Operating from bases in Doncaster and Prudhoe, Converse Pharma Group currently employs 980 members of staff across its 12 sites in the UK and Ireland. Its 140 strong sales team has helped revenues increase sharply in recent years, having achieved sales of £250m in 2018 – up from £188m the previous year. The funding provided by RBS and Secure Trust Bank will enable the company to invest in new, larger depots, increasing the depth and range o…
Scientists at the University of Eastern Finland and the University of Oxford have shown that small RNA molecules occurring naturally in cells, i.e. microRNAs, are also abundant in cell nuclei. Previously, microRNAs were mainly thought to be found in cytoplasm. The scientists also discovered that microRNA concentrations in cell nuclei change as a result of hypoxia. The findings strongly suggest that microRNAs play a role in the expression of genes in the cell nucleus. This observation is crucial for the development of novel gene therapy, among other things. The study was published in Scientific Reports today. The scientists profiled the division of microRNAs in different parts of endothelial cells, discovering that a large share of microRNAs are enriched in cell nuclei. When the scientists…
Novartis, Amgen and Banner Alzheimer's Institute today announced the decision to discontinue investigation of the BACE1 inhibitor CNP520 (umibecestat) in two pivotal Phase II/III studies in the Alzheimer's Prevention Initiative Generation Program. An assessment of unblinded data during a regular pre-planned review identified worsening in some measures of cognitive function. Given these findings, the sponsors concluded that the potential benefit for participants in the studies did not outweigh the risk. John Tsai (M.D.), Head of Global Drug Development and Chief Medical Officer, said: "Novartis has a strong research focus and commitment to patients. As researchers we have to accept today's disappointing news as part of the search for innovative new treatments. We remain committed to advanci…
Commenting on the government response to the Promoting professionalism, reforming regulation consultation, Danny Mortimer, chief executive of NHS Employers, said: “Employees and employers will welcome steps to make the fitness to practise process quicker, fairer and effective; they will also look forward to further reform, which will allow the regulation of new roles and professions to support their full deployment to care for our patients.”
A prestigious competition that has helped innovators raise millions of pounds to take their concepts to the global marketplace is looking for 2019’s most life-changing creations. The Royal Society of Chemistry’s Emerging Technologies Competition has helped winners raise more than £32million in funding since it was launched in 2013. Backed by some of the world’s biggest companies, such as Unilever, Croda, Johnson Matthey, RSSL and Pfizer, entries are now open until 5 July for the next big success story whose mastery of the chemical sciences helped create a product that can deliver a real-world benefit for wider society. Aurora Antemir, a senior manager in the Royal Society of Chemistry’s Industry team said: “In less than a decade, the Emerging Technologies Competition has gone from being an…
New Brand Identity Sets the Stage for a New Pure-play Commercialisation Partner to the Pharmaceutical Industry Yardley, PA and London, UK – May 29, 2019 - PHS Health Solutions (PHS), a leading pharmaceutical contract commercial organisation with an exemplary 35-year track record as a trusted partner for its customers, announces that beginning today, the company will operate under the new identity of Amplity Health. The new corporate brand represents a pure-play pharmaceutical commercialisation business that integrates a family of brands including Touchpoint, PDI and Tardis Medical, offering customised and multi-channel medical, remote engagement, and sales solutions, along with strategic consulting and organisational capability development for pharmaceutical, biotechnology, medical device,…
London, UK – 23 April 2019: Ergomed plc, (LSE: ERGO) ('Ergomed' or the 'Company'), a company focused on providing specialised services to the pharmaceutical industry, today announces that PrimeVigilance, its pharmacovigilance, regulatory and medical information service provider, has been awarded the Queen’s Award for Enterprise for the second time reinforcing Ergomed’s broad leadership position as a provider of contract services. Now in its 53rd year, the Queen’s Awards for Enterprise are the most prestigious business awards in the country. Ergomed’s PrimeVigilance has received the 2019 Queen’s Award for International Trade in recognition of its year-on-year outstanding services in the drug safety sector for its global customer base. As an International Trade winner, PrimeVigilance has dem…
Berkshire based PharmiWeb are excited to have launched a new version of of PharmiWeb.com - The new site, focusing on News, Events and Articles from the Pharma sector, brings together a wide range of content from multiple sources, to make the site an even better resource for the Pharma Industry.  Pharma Jobs  The hugely popular Job Board has moved to a new URL - PharmiWeb.Jobs. This means that for individuals looking for a the latest jobs in the pharma industry, PharmiWeb's new job board will the only place they need to go!  According to Portal Business Manager, Mike Wood - "This is the start of a very exciting growth stage for PharmiWeb, and we have a wide ranging plan of developments for the portal which will reinforce our position as one of the primary sources of global Pharma news. Our…
CeloNova BioSciences, Inc. (CeloNova), a global medical device company that offers a family of innovative products based upon its proprietary Polyzene™-F nanocoating technology, today announced that it has signed a three-year group purchasing agreement with HealthTrust for its novel COBRA PzF™ NanoCoated Coronary Stent (NCS) System. The agreement (contract number: 39949), which became effective on February 1, 2019, provides HealthTrust's more than 1,500 member hospitals and health systems with access to the world's first non drug-eluting, nanocoated coronary stent designed to help physicians safely and effectively treat patients who may benefit from short, 1-month minimum dual antiplatelet therapy (DAPT).1 DAPT has been shown to increase bleeding and mortality risks, which is of greater c…
*         ICARIA (Isatuximab in Combination with pomalidomide And low-dose dexamethasone veRsus pomalidomide and low dose dexamethasone in patients with refractory or relapsed And refractory Multiple Myeloma), study evaluated the benefit of isatuximab in combination with standard of care in prolonging progression free survival as compared to standard of care in patients with relapsed/refractory multiple myeloma *         Multiple myeloma is the second most common haematological cancer1 *         First randomised Phase 3 trial to evaluate the benefit of adding a monoclonal antibody to pomalidomide and dexamethasone for treatment of relapsed/refractory multiple myeloma I…
Merck, a leading science and technology company, and GSK, a science-led global healthcare company, today announced that the companies have entered into a global strategic alliance to jointly develop and commercialize M7824 (bintrafusp alfa*). M7824 is an investigational bifunctional fusion protein immunotherapy that is currently in clinical development, including potential registration studies, for multiple difficult-to-treat cancers. This includes a Phase II trial to investigate M7824 compared with pembrolizumab as a first-line treatment in patients with PD-L1 expressing advanced non-small cell lung cancer (NSCLC).   M7824 is designed to simultaneously target two immuno-suppressive pathways, transforming growth factor-β (TGF-β) trap and an anti-programmed cell death ligand-1 (PD-L1…
Torque, an immuno-oncology company developing first-in-class Deep Primed™ T Cell Therapeutics to direct immune power deep within the tumor microenvironment, and Thermo Fisher Scientific Inc. (NYSE: TMO), today announced a collaboration to build a dedicated Slipstream™ manufacturing facility for high-efficiency production of Torque's Deep-Primed T cell immunotherapies. Buildout of the Torque/Thermo Fisher manufacturing facility has begun, and the companies anticipate processing patient cells by the end of 2019. The Slipstream platform will initially be used in the clinical development of Torque's lead Deep-Primed T cell candidate, TRQ-1501, in solid and hematologic tumors; followed by TRQ-1201, also for solid and hematologic tumors. "Torque's cell manufacturing technology platform is crit…
Neuraxpharm Group, a leading European specialty pharmaceutical company focused on the treatment of central nervous system disorders (CNS), announces the acquisition of Farmax, a CNS specialty pharmaceutical company, from SVUS Pharma.   Farmax, located in Hradec Králové, Czech Republic, was the commercial division of SVUS Pharma, and has a strong distribution presence in the Czech Republic, Slovakia as well as a small presence in Hungary. Farmax is a leader in sales and marketing both branded and non-branded generics pharmaceuticals for CNS disorders such as Zolpinox®. It also commercializes well-known OTC nutraceuticals such as Preventan® and Maxicor®. Farmax has been renamed Neuraxpharm Bohemia and will commercialize its products under the Neuraxpharm brand. Leveraging its proprie…
The Janssen Pharmaceutical Companies of Johnson & Johnson today announced a worldwide collaboration and license agreement with MeiraGTx Holdings plc (NASDAQ: MGTX), a clinical-stage gene therapy company, to develop, manufacture and commercialize its clinical stage inherited retinal disease portfolio, including leading product candidates for achromatopsia (ACHM) caused by mutations in either CNGB3 or CNGA3, and X-linked retinitis pigmentosa (XLRP). Further, the companies have formed a research collaboration to explore new targets for other inherited retinal diseases and further develop adeno-associated virus (AAV) manufacturing technology. "Janssen is excited to expand our portfolio with the addition of innovative assets that have the potential to improve sight or prevent the progressi…
Beckman Coulter Life Sciences today announced its acquisition of Labcyte, a privately held, acoustic liquid handling company based in San Jose, California. Labcyte is best known for its Echo® acoustic droplet ejection technology, which uses sound waves to transfer tiny amounts of liquid with unequalled speed and accuracy. This technology—the centerpiece of Labcyte's Echo Liquid Handlers—enables walkaway convenience and integration capabilities. Labcyte technology enables faster and more cost-effective laboratory workflows in applications such as drug discovery and genomics. "Labcyte's unique product portfolio complements our existing liquid handling and laboratory automation business. It provides new opportunities to develop and enhance time-saving solutions for customer workflows," said J…
UPMC Health Plan and AstraZeneca today announced the initiation of a pioneering value-based contract effective Jan.1, 2019 for UPMC for Life Medicare members who are prescribed BRILINTA® (ticagrelor), a medication used to lower a patient's chances of having another heart attack or dying from one in the 12 months following a heart attack. The goal of the contract is to align the incentives of the manufacturer, AstraZeneca, with UPMC Health Plan by connecting reimbursement for BRILINTA® to clinical outcomes in a real-world population. Specifically, reimbursement for the medication will be linked to cardiovascular outcomes for people treated with BRILINTA® following a recent hospitalization for heart attack or unstable angina. This value-based contract is groundbreaking in two way…
Purdue Pharma L.P. (“Purdue”) and Alivio Therapeutics today announced that they have entered into a partnership to advance one of Alivio’s product candidates through clinical development with an option exercisable by Purdue to collaborate on a limited number of additional compounds utilising Alivio’s inflammation-targeting technology. ALV-107 is a non-opioid treatment being developed for interstitial cystitis/bladder pain syndrome (IC/BPS).   Alivio will receive up to $14.75 million in upfront and near-term license exercise payments and is eligible to receive royalties on product sales and over $260 million in research and development milestones. Purdue also has an option to invest in Alivio’s next equity financing.   “This collaboration with Alivio is an important milestone…