Biotech - Articles

Precision-fermented proteins offer the tantalising prospect of radically uncoupling our nutrition from arable land. However, the journey from laboratory titre to multi-kiloton commodity supply chains has many non-trivial hurdles in between.
Protein fermentation describes the microbial population's controlled breakdown and build-up of nitrogenous compounds under specific redox potential, pH balance and substrate limitation constraints. The process generally begins with the extracellular degradation of high molecular weight proteins. Protein hydrolysis by microbial aspartic proteases (fungi) or metalloproteases (bacteria) yields oligopeptides (2–20 residues) that are taken up into the cell via specific oligopeptide permeases. Intracellular di- and tri-peptidases further hydrolyze peptide…

In chemistry, materials science and many industries, polyethylene glycol (PEG) and ethylene glycol (EG) are two very crucial chemicals. Both are structurally similar but very different in terms of physical characteristics, chemical characteristics and functional fields.
Chemical Structure and Molecular Weight Polyethylene Glycol is the polymer form of EG, with its molecular weight varying depending on the degree of polymerization. The molecular weight of PEG generally ranges from hundreds to tens of thousands, while EG has a molecular weight of only 62. This difference in molecular weight leads to significant differences in their physical properties and applications. The polymer structure of PEG gives it higher viscosity and better biocompatibility, whereas EG's low molecular weight r…

Artificial intelligence (AI) is rapidly transforming biomarker discovery by unlocking insights from vast and complex datasets. Hurdle recently reviewed how revolutionary this technology could be, while also highlighting the potential hurdles that still stand in the way of its translation into the clinic.
Artificial intelligence (AI) is rapidly transforming biomarker discovery by unlocking insights from vast and complex datasets. Hurdle recently reviewed how revolutionary this technology could be, while also highlighting the potential hurdles that still stand in the way of its translation into the clinic.   The Explosion of Data: Bigger, Broader, More ComplexLarge cohort studies are no longer a curiosity; they’re foundational. Crucially, these cohorts increasingly link rich electronic h…

In longitudinal clinical trials, missing data is a threat to scientific integrity. Whether due to patient dropouts, missed visits, or protocol deviations, these gaps can distort results, reduce statistical power, and invite regulatory scrutiny. With dropout rates averaging around 3-8% for the last three years, the stakes are high. As the industry continues to evolve, so should the strategies we implement.
In longitudinal clinical trials, missing data is a threat to scientific integrity. Whether due to patient dropouts, missed visits, or protocol deviations, these gaps can distort results, reduce statistical power, and invite regulatory scrutiny. With dropout rates averaging around 3-8% for the last three years, the stakes are high. As the industry continues to evolve, so should the str…

The global Penicillin Active Pharmaceutical Ingredients (API) market was valued at USD 2.95 billion in 2023 and is projected to reach USD 4.79 billion by 2032, growing at a CAGR of 5.6%. This growth is driven by the increasing demand for antibiotics, advancements in manufacturing technologies, and the expansion of healthcare infrastructure in emerging economies. The report provides an in-depth analysis of market trends, key players, and regional dynamics, offering valuable insights for stakeholders in the pharmaceutical industry.
The Penicillin Active Pharmaceutical Ingredients (APIs) market represents a cornerstone of the global pharmaceutical industry, providing the essential building blocks for antibiotics that combat a wide range of bacterial infections. With its critical role in health…

The global Ambulatory EHR Market is projected to grow from USD 6.1 billion in 2023 to USD 10.5 billion by 2032 at a CAGR of 6.3%. Explore market size, major regional trends, deployment shifts toward cloud/web-based models, leading vendors, and what to expect through 2032 in this comprehensive analysis guided by Ameco Research.
In recent years, the healthcare industry has undergone rapid digital transformation. Among its key components is the adoption of Ambulatory EHR (Electronic Health Records in outpatient / ambulatory care settings) systems. These solutions are essential tools for physician offices, specialty clinics, and other outpatient facilities to maintain accurate patient histories, manage clinical workflows, enable remote care protocols, and meet regulatory requirements. As pressu…

Multiple System Atrophy Therapeutics is an evolving field focused on treating a rare neurodegenerative disease with no cure. This article examines the Multiple System Atrophy Therapeutics Market, its size, growth drivers, recent product development, regional trends, key players, and what lies ahead up to 2033—based largely on the report by Acumen Research And Consulting.
What is Multiple System Atrophy and the Role of Therapeutics Multiple System Atrophy (MSA) is a progressive, rare neurodegenerative disorder adversely affecting the autonomic nervous system, movement, balance, coordination, and various bodily functions. Patients experience tremor, parkinsonian symptoms, cerebellar dysfunction, autonomic dysregulation (blood pressure, bladder control), and rapidly declining ability to perfor…

The CBH Biospecimen Marketplace is an online biobank and biorepository built for teams who need human biological samples with audit-ready documentation and dependable logistics. Our continuously curated biological specimen inventory exceeds a quarter of a million active units and spans serum, plasma, whole blood, PBMC for research, urine samples, cerebrospinal fluid (CSF), saliva, stool/feces/faeces, swab samples, and human tissue (FFPE and frozen). You can search, filter, compare, and order human biospecimens for research, development, and production—not only RUO feasibility. What differentiates the platform is scientific traceability: standardized preanalytics, transparent biospecimen data, and route-proven cold-chain shipping.
  What Counts as a Human Biological Specimen? Human biol…

Nutrigenomics is reshaping how we understand the connection between genes and diet. This article explores how DNA insights can guide personalized nutrition, improve long-term wellness strategies, and empower individuals to make informed lifestyle choices. With privacy-first, on-device processing, Noorns provides a secure and innovative approach to DNA-based health insights, bridging science and everyday health.
Nutrigenomics, the study of how our genes interact with diet, is emerging as one of the most promising areas in personalized health. Genetic variations can influence how we metabolize nutrients, respond to supplements, and manage risks for chronic conditions. Understanding these patterns opens new opportunities for preventative care, optimized wellness strategies, and more targeted i…

Design alone is no longer enough to bring transformative products to life. While great design sparks creativity and defines user experience, development is what turns vision into reality. At Hurdle, we believe that true innovation demands more than following a conventional design process-it requires a smarter, more holistic approach that aligns strategy, technology, and market readiness.
A successful design and development process must balance exploration with structure, enabling teams to build high-quality products efficiently while adapting to change along the way. Yet, while the traditional design process may comprise four to five defined phases, Hurdle believes there is more to consider from the outset. Elements such as business analysis, capability planning, budgetary controls, capabil…

The United States Food and Drug Administration’s (FDA’s) Accelerated Approval (AA) pathway, initially established in 1992 during the HIV/AIDS epidemic to provide faster access to life-saving treatments, has been instrumental in expediting access to therapies for serious and life-threatening conditions. It is particularly significant in therapeutic areas, such as rare diseases, where surrogate or intermediate clinical endpoints may be necessary due to limited patient populations or slow disease progression. While this approach has encouraged innovation, it has also raised concerns about drugs staying on the market without confirmed evidence of their effectiveness.
The United States Food and Drug Administration’s (FDA’s) Accelerated Approval (AA) pathway, initially established in 1992 during…

From sequence to 30 L and manufacturing scale, why outsourcing saves resources in the long run and makes economic sense.
Isomerase is a leading bioprocessing company that offers partners the ability to scale up their processes or projects from the lab to industrial manufacturing. Partners from various industries, including pharma, biotech, as well as food and ingredients, opt to work with our bioprocessing services when scaling. In this article, we provide an overview of what we offer, enabling you to make an informed decision when considering outsourcing.   What is microbial bioprocessing? Once a microbe and the product of interest have been optimised, by engineering the production strain and/or target sequence, the process needs to be scaled. Generating such a product within a livin…

The intimate wash care products industry is projected to grow steadily through 2032, driven by changing hygiene standards, rising awareness, and evolving consumer preferences. Explore trends, market share insights, and growth drivers.
In recent years, the global health and wellness industry has seen an unprecedented evolution—not only in mainstream personal care but also in intimate hygiene. Among the most dynamic and increasingly visible segments is the intimate wash care products category, which has transitioned from niche awareness to everyday consumer routines in many parts of the world. As per data released by Acumen Research and Consulting, the global intimate wash care product market was valued at USD 28.6 billion in 2023 and is projected to reach USD 45.9 billion by 2032, expanding…

Examine the Regenerative Medicine Scaffolds Market growth—from USD 336.5 Million in 2023 to USD 1.72 Billion by 2032 at a 20.2% CAGR. Learn key trends, technology advances, regional dynamics, and tissue repair innovations reshaping healthcare.
Biomaterials engineered to restore, replace, or augment damaged tissues are gaining momentum—and at the core are Regenerative Medicine Scaffolds, critical in advancing tissue repair across orthopedics, neurology, wound healing, and cardiovascular applications. Our recent analysis at Acumen Research & Consulting sheds light on shifting market dynamics, emerging technologies, and region-wise growth projections. Market Size & Growth Outlook The Regenerative Medicine Scaffolds Market Size reached USD 336.5 million in 2023 and is forecast to so…

Fermentation development is the key to scaling bio-based innovation. Here we cover Isomerase’s step-by-step approach, from strain selection to downstream integration, helping biotech, pharma, and food tech companies accelerate reliable, scalable microbial production.
Microbial Fermentation Services: From Strain Design to Scalable Process Fermentation is one of the oldest biotechnologies, yet it’s now driving some of the most cutting-edge innovations in health, nutrition, and sustainability. From therapeutic enzymes and precision fermentation ingredients to biodegradable materials and alternative proteins, microbial fermentation has re-emerged as a core engine of the modern bioeconomy. However, while the science behind engineered microbes is advancing rapidly, the path from disc…

Understanding the basic systems crucial to cosmetic formulations is key for both novice and experienced cosmetic chemists.
In the rapidly evolving world of cosmetics, the quest for innovating sublime performing products starts with a solid foundation of formula design. Understanding the basic systems crucial to cosmetic formulations is key for both novice and experienced cosmetic chemists. These foundational systems ensure that the product not only meets consumer expectations but also adheres to safety and efficacy standards. Here, we delve into the seven essential systems that serve as the backbone for cosmetic formula design: Emulsification System, Efficacy System, Thickening System, Antioxidant System, Preservative System, Sensory Modification System, and Safety Assurance System. Emulsif…

Read on to explore how we’re setting a new standard in peptide delivery. This initiative is strategically designed to accelerate the drug discovery journey for small-molecule-focused biotech companies by providing peptides with speed, precision, and reliability.
Timely access to high-quality peptides is essential in drug discovery, especially for screening, structure-activity relationship (SAR) studies, and early-stage preclinical research. Any delay in peptide synthesis can slow down critical experiments, affect project timelines, and limit the ability to make rapid decisions in lead optimisation. Recognising the critical role of fast, reliable, and risk-free peptide delivery in accelerating the development of new therapies, launched the o2h Peptide Guarantee Programme, designed to deliver…

The Medical Telepresence Robots Market is projected to grow from USD 66.2 million in 2023 to USD 322.1 million by 2032, at a CAGR of 19.3%. This growth is driven by the rise in telemedicine, healthcare professional shortages, aging populations, and the need for infection control. Key market trends include AI integration, 5G connectivity, and expanding use in hospitals, home care, and senior living. North America leads the market, with Asia-Pacific emerging as the fastest-growing region.
Medical Telepresence Robots Market Overview: Unlocking the Future of Remote Healthcare In an increasingly digital healthcare landscape, Medical Telepresence Robots are emerging as a game-changing solution to bridge gaps in care delivery, especially in underserved or geographically distant locations. Accordin…

HPAPIs: Small but Mighty...in Big Pharma Development: Today’s drug developers have never faced smaller and more potent therapeutics than those emerging in the HPAPI space. Yet these molecules pack a punch: while they are delivered in microgram or milligram doses, the requirements for safety, compliance and technical know-how are huge. As pharma companies look for nimble and expert partners in their supply chains, CDMOs active in HPAPIs and oncology are moving from specialty to mainstream in this field.
The High Potency Active Pharmaceutical Ingredient (HPAPI) contract manufacturing market is red hot right now. Shifts to targeted and more personalized medicines (especially oncology, hormonal, and autoimmune drugs), coupled with the continued need for high-volume API supply are opening the…

The CDMOs behind active pharmaceutical ingredients are no longer silent suppliers—they are strategic partners shaping the future of medicine. As therapies get more complex and the pharmaceutical supply chain becomes more decentralized and transparent, the API CDMO market is ready to deliver—faster, safer, and smarter.
The Active Pharmaceutical Ingredient (API) CDMO market has entered the limelight as global pharma pipelines continue to balloon, while speed to market, safety and scalability requirements also ramp up. The API CDMO market size is expected to rise at a steady pace through 2030. Driving factors include global outsourcing trends, supply chain decentralization, and a host of industry reforms to improve quality, transparency, efficiency, and resilience. Active pharmaceutical ingred…