Medical comms - Articles
With bacteriological diseases such as SARS and MRSA on the increase and with concern about these diseases at an all time high, the medical community is under tremendous pressure to implement measures in order to minimise the risk of potential outbreaks. Recent official reports suggest that MRSA can be found in 40 per cent of UK hospitals . Transmission occurs through coming into contact with an object carrying the bacteria or via direct skin-to-skin exposure. Hospitals therefore have an up-hill struggle to eradicate superbugs. …
Dementia is a neurodegenerative and devastating disease Dementia is a degenerative disease of the brain that progressively destroys the neurons controlling memory, language and reasoning. It progresses at different rates in different people. It is estimated that dementia currently affects nearly 18 million people worldwide (1). As the mean age of the population increases, these numbers are steadily increasing. Forms of dementia and their estimated prevalence: 1 Alzheimer's disease (AD) 55% Vascular dementia (VaD)20% Dementia with Lewy bodies (DLB) and dementia…
DailyUpdates 3rd February, 2006: The size of the cytotoxic market in the seven major pharmaceutical markets is estimated to be approximately $9.6 billion. Datamonitor expects it to reach a peak of $12.8 billion by 2009. However, mainly due to major patent expiries, it is expected to drop to $11.3 bi…
The market for antibacterials, valued at $24 billion in the seven major markets, faces significant revenue loss in the period 2005-2007 due to major patent expiries (see Commercial Insight: Antibacterials). Despite the problems faced by companies involved in antibacterials considerable success has been met by th…
DailyUpdates Jan 31st: OX40:OX40L interaction – evolving from a key component of autoimmunity to a possible target for cardiovascular disease OX40 (CD134) is one of the newer tumor necrosis factor receptor (TNFR) family members. Expressed on CD4+ T-cells, its activation by OX40L, a type II membrane protein expressed on activated B-cells, dendritic cells and macrophages, plays an important T-cell co-stimulatory role. In our recent feature on Autoimmun…
Source DailyUpdates Jan 25th: As information technology becomes increasingly important in drug R&D, the application of bioinformatics/informatics applications has the potential to drive growth in the worldwide pharmaceuticals drug market from the $240 billion today to $3 trillion by 2020.The role of bioinformatics/informatics in the drug d…
In 1999 Human Genome Sciences researchers published a study in the journal Science describing a new member of the TNF super-family which they named BLyS. Since that time our understanding of this protein, also known as BAFF, and its homologue APRIL has progressed rapidly. The BAFF sub-family has emerged as a candidate target for therapies of various autoimmune diseases…
A new study shows the oral iron-chelator Ferriprox (deferiprone) prevents patients with thalassaemia experiencing heart complications and dying of heart failure. Patients with the condition require frequent blood transfusions with the unwanted effect of excess iron that can build up in organs…
By: Brian S. Robinson i3, Vice-President, Global Marketing www.i3global.com There is little mystery about what the next few years hold for the clinical research industry –it comes down to one word: speed. It is all about speed. The gauntlet has been thrown down and the companies that are able to demonstrate an effective and consistent approach to truncating the timeline of clinical trials will be very successful. Speed is not a capabili…
Electronic Data Capture (EDC), three little words that can divide the clinical research community like few others. To some, EDC is a panacea for all the troubles and rising costs of the clinical development process, whilst to others it spells broken promises, and forms the butt of many less than flattering anecdotes. But what is the reality, and where is the border between the promise of providers and the expectation of end users? This article is not designed to provide d…
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Dr Adam Meijer of the Netherlands-based European Influenza Surveillance Scheme (EISS)§ has highlighted the vital role rapid testing must play in combating the global threat of bird flu. Dr Meijer makes his observations in the January issue of Expert Review of Molecular Diagnostics. Until now, the last requirement for avian influenza viruses to cause a pandemic – efficient transmission between humans – has fortunately not been met. However, the devastating effect of the A(H5N1) bird flu on poultry holdings, and he…
New data presented at the American Society of Hematology meeting in Atlanta this month suggest the problems associated with iron overload in frequently-transfused patients can now be managed simply with an oral treatment rather than continuous infusions of several hours duration. Iron was removed from the blood and tissues of patients just as safely and effectively with the novel once-daily oral chelator treatment deferasirox (Exjade) as with the standard older injectable iron chelator deferoxamine. Th…
Most patients who develop chronic myeloid leukaemia (CML) can now expect to live more than 20 years from diagnosis if they are treated with the tyrosine kinase inhibitor (TKI) Glivec (imatinib) according to haematologists involved in the IRIS (International Randomized Interferon versus STI571) study. Before availability of current treatments, median survival from diagnosis was 3.5 years. Around 95 pe…
New Biologics revolutionizing treatment of colorectal cancer The market for colorectal cancer therapies has increased by over seven-fold since 2000. The increase in the value of this market can be explained by new and improved chemotherapeutic agents now on the market, the introduction of key biologic therapies, and improved chemotherapeutic regimens which take into account various new options. The late-stage pipeline for colorectal cancer therapies is curr…
Dronedarone, a new Class III multi-channel blocking anti-arrhythmic drug currently in Phase III development by Sanofi-Aventis for the prevention of atrial fibrillation (AF) and atrial flutter (AFL) may help fill the unmet need for a safe pharmacologic treatment that effectively controls atrial fibrillation, cardiologists sa…
Patients who could benefit from injectable therapies are a lot less needle-phobic than doctors assume, according to research conducted by pharmacist and behavioural scientist Professor Robert Horne. The “Open Mind” study presented at the 10th European AIDS Conference/EACS in Dublin showed over three quarters of patients would be willing to accept self-administered subcutane…
Recruitment websites can be confusing, strange places to the inexperienced. If you are not sure, select an established agency with a name you recognise. Follow the link to their website and find a contact name. Email or phone them to ask for advice. If the website doesn’t give you information about their recruiters, maybe it is best to give them a miss. Using the internet is supposed to be speedy and convenient. However, a common complaint we hear is that sending off a CV to some recruitm…
We are pleased to announce that, due to demand, we have added a new section to the site. Executives in the Pharmaceutical industry can now find the best selection of jobs with packages of £100K+ (GBP) per year. These executive pharma jobs are automatically taken from our extensive database of over 4800 live jobs, provided by our partners in Agencies and PharmaCos across the industry. This means that the listing will be constantly updated with new jobs as soon as they are posted. Visit our new Executive Jobs page here.