Research and development - Articles
Polyethylene glycol (PEG) is a versatile polymer widely employed in various industries, including pharmaceuticals, biotechnology, and materials science.
Its unique properties, such as biocompatibility, hydrophilicity, and flexible structure, make it an ideal candidate for myriad applications ranging from drug delivery systems to surface modification of biomaterials. PEG Synthesis has emerged as a critical approach to meet the specific needs of these diverse applications, enabling researchers and manufacturers to design PEG derivatives that offer enhanced performance and functionality. Understanding PEG and Its Importance PEG is a polymer that consists of repeating units of ethylene glycol. It is available in various molecular weights, which directly influence its physical and ch…
Its unique properties, such as biocompatibility, hydrophilicity, and flexible structure, make it an ideal candidate for myriad applications ranging from drug delivery systems to surface modification of biomaterials. PEG Synthesis has emerged as a critical approach to meet the specific needs of these diverse applications, enabling researchers and manufacturers to design PEG derivatives that offer enhanced performance and functionality. Understanding PEG and Its Importance PEG is a polymer that consists of repeating units of ethylene glycol. It is available in various molecular weights, which directly influence its physical and ch…
BOC Sciences will present at ACS Fall 2025 (Booth #2230), one of the largest scientific conferences held by the American Chemical Society (ACS).
As the daunting challenges the world has been facing continue to bring an impact to the biopharmaceutical industry, this year's hybrid event, onsite in Washington, DC and virtually on 17-21 August, presents one more opportunity for BOC Sciences to demonstrate its world class capabilities for helping to make innovation in pharmaceuticals, biotech, and materials a reality. Exhibition details: Event Date: August 17–21, 2025 Venue: Washington, DC & Virtual Exhibition Booth: #2230 Meeting Booking Channel: https://www.bocsci.com/events/boc-sciences-at-acs-fall-2025.html At Booth #2230, BOC Sciences will spotlight its most adva…
As the daunting challenges the world has been facing continue to bring an impact to the biopharmaceutical industry, this year's hybrid event, onsite in Washington, DC and virtually on 17-21 August, presents one more opportunity for BOC Sciences to demonstrate its world class capabilities for helping to make innovation in pharmaceuticals, biotech, and materials a reality. Exhibition details: Event Date: August 17–21, 2025 Venue: Washington, DC & Virtual Exhibition Booth: #2230 Meeting Booking Channel: https://www.bocsci.com/events/boc-sciences-at-acs-fall-2025.html At Booth #2230, BOC Sciences will spotlight its most adva…
Fermentation development is the key to scaling bio-based innovation. Here we cover Isomerase’s step-by-step approach, from strain selection to downstream integration, helping biotech, pharma, and food tech companies accelerate reliable, scalable microbial production.
Microbial Fermentation Services: From Strain Design to Scalable Process Fermentation is one of the oldest biotechnologies, yet it’s now driving some of the most cutting-edge innovations in health, nutrition, and sustainability. From therapeutic enzymes and precision fermentation ingredients to biodegradable materials and alternative proteins, microbial fermentation has re-emerged as a core engine of the modern bioeconomy. However, while the science behind engineered microbes is advancing rapidly, the path from disc…
Microbial Fermentation Services: From Strain Design to Scalable Process Fermentation is one of the oldest biotechnologies, yet it’s now driving some of the most cutting-edge innovations in health, nutrition, and sustainability. From therapeutic enzymes and precision fermentation ingredients to biodegradable materials and alternative proteins, microbial fermentation has re-emerged as a core engine of the modern bioeconomy. However, while the science behind engineered microbes is advancing rapidly, the path from disc…
Understanding the basic systems crucial to cosmetic formulations is key for both novice and experienced cosmetic chemists.
In the rapidly evolving world of cosmetics, the quest for innovating sublime performing products starts with a solid foundation of formula design. Understanding the basic systems crucial to cosmetic formulations is key for both novice and experienced cosmetic chemists. These foundational systems ensure that the product not only meets consumer expectations but also adheres to safety and efficacy standards. Here, we delve into the seven essential systems that serve as the backbone for cosmetic formula design: Emulsification System, Efficacy System, Thickening System, Antioxidant System, Preservative System, Sensory Modification System, and Safety Assurance System. Emulsif…
In the rapidly evolving world of cosmetics, the quest for innovating sublime performing products starts with a solid foundation of formula design. Understanding the basic systems crucial to cosmetic formulations is key for both novice and experienced cosmetic chemists. These foundational systems ensure that the product not only meets consumer expectations but also adheres to safety and efficacy standards. Here, we delve into the seven essential systems that serve as the backbone for cosmetic formula design: Emulsification System, Efficacy System, Thickening System, Antioxidant System, Preservative System, Sensory Modification System, and Safety Assurance System. Emulsif…
The Medical Telepresence Robots Market is projected to grow from USD 66.2 million in 2023 to USD 322.1 million by 2032, at a CAGR of 19.3%. This growth is driven by the rise in telemedicine, healthcare professional shortages, aging populations, and the need for infection control. Key market trends include AI integration, 5G connectivity, and expanding use in hospitals, home care, and senior living. North America leads the market, with Asia-Pacific emerging as the fastest-growing region.
Medical Telepresence Robots Market Overview: Unlocking the Future of Remote Healthcare In an increasingly digital healthcare landscape, Medical Telepresence Robots are emerging as a game-changing solution to bridge gaps in care delivery, especially in underserved or geographically distant locations. Accordin…
Medical Telepresence Robots Market Overview: Unlocking the Future of Remote Healthcare In an increasingly digital healthcare landscape, Medical Telepresence Robots are emerging as a game-changing solution to bridge gaps in care delivery, especially in underserved or geographically distant locations. Accordin…
HPAPIs: Small but Mighty...in Big Pharma Development:
Today’s drug developers have never faced smaller and more potent therapeutics than those emerging in the HPAPI space. Yet these molecules pack a punch: while they are delivered in microgram or milligram doses, the requirements for safety, compliance and technical know-how are huge. As pharma companies look for nimble and expert partners in their supply chains, CDMOs active in HPAPIs and oncology are moving from specialty to mainstream in this field.
The High Potency Active Pharmaceutical Ingredient (HPAPI) contract manufacturing market is red hot right now. Shifts to targeted and more personalized medicines (especially oncology, hormonal, and autoimmune drugs), coupled with the continued need for high-volume API supply are opening the…
The High Potency Active Pharmaceutical Ingredient (HPAPI) contract manufacturing market is red hot right now. Shifts to targeted and more personalized medicines (especially oncology, hormonal, and autoimmune drugs), coupled with the continued need for high-volume API supply are opening the…
As awareness grows and technology advances, Guillain-Barré Syndrome is becoming less of a mystery—and more of a manageable, diagnosable condition. The future of GBS care starts with faster answers.
While it is not a common condition, Guillain-Barré Syndrome (GBS) is garnering increased interest from the broader medical diagnostics industry as new cases are reported worldwide each year and linked to a range of triggers including infections, immunizations, or idiopathic origins. Early detection followed by appropriate care and treatment is a key need in GBS, which can lead to paralysis and other serious complications if left untreated. The global Guillain-Barré Syndrome diagnostics market is expected to show steady growth during the forecast period (2024-2030) with several factors such as gr…
While it is not a common condition, Guillain-Barré Syndrome (GBS) is garnering increased interest from the broader medical diagnostics industry as new cases are reported worldwide each year and linked to a range of triggers including infections, immunizations, or idiopathic origins. Early detection followed by appropriate care and treatment is a key need in GBS, which can lead to paralysis and other serious complications if left untreated. The global Guillain-Barré Syndrome diagnostics market is expected to show steady growth during the forecast period (2024-2030) with several factors such as gr…
An overview of alternative microbial hosts, such as E. coli, B. subtilis, Pichia, and S. cerevisiae, for recombinant bioactive production: Benefits and industrial use cases.
An Overview of Alternative Microbial Hosts for Recombinant Bioactive Production: Benefits and Industrial Use Cases Selecting the right microbial host is a major step for any biotechnology project, whether you are producing food-grade enzymes, pharmaceutical ingredients or industrial bioproducts. Your choice of production host can affect your project’s yield, product quality, scalability and regulatory approval with administrations such as the FDA. In this article, we share how to navigate these choices while analysing the advantages and use cases of our four IsoChassisTM microbial hosts. These strains include&…
An Overview of Alternative Microbial Hosts for Recombinant Bioactive Production: Benefits and Industrial Use Cases Selecting the right microbial host is a major step for any biotechnology project, whether you are producing food-grade enzymes, pharmaceutical ingredients or industrial bioproducts. Your choice of production host can affect your project’s yield, product quality, scalability and regulatory approval with administrations such as the FDA. In this article, we share how to navigate these choices while analysing the advantages and use cases of our four IsoChassisTM microbial hosts. These strains include&…
This article discusses the significance, applications, and benefits of biotinylated nucleotides in the realms of research and diagnostics.
Biotinylated nucleotides have emerged as a powerful tool in molecular biology, enabling researchers to explore genetic materials with unprecedented precision and sensitivity. These modified nucleotides, attached to the vitamin biotin, facilitate a variety of applications, including nucleic acid labeling, detection, and manipulation. What Are Biotinylated Nucleotides? Biotinylated nucleotides are nucleotide molecules that have been chemically modified to include a biotin group -- a small, water-soluble vitamin known for its strong affinity for avidin or streptavidin. This affinity allows biotinylated nucleotides to be easily captured and detec…
Biotinylated nucleotides have emerged as a powerful tool in molecular biology, enabling researchers to explore genetic materials with unprecedented precision and sensitivity. These modified nucleotides, attached to the vitamin biotin, facilitate a variety of applications, including nucleic acid labeling, detection, and manipulation. What Are Biotinylated Nucleotides? Biotinylated nucleotides are nucleotide molecules that have been chemically modified to include a biotin group -- a small, water-soluble vitamin known for its strong affinity for avidin or streptavidin. This affinity allows biotinylated nucleotides to be easily captured and detec…
This article delves into the significance, techniques, and applications of microbial genome editing services, illustrating their transformative impact on modern science.
Innovation in biotechnology has reached new heights with the advancement of microbial genome editing services. These services enable researchers and industries to modify the genetic makeup of microorganisms, such as bacteria and yeast, with remarkable precision. As a result, microbial genome editing has become a cornerstone in various fields, including agriculture, medicine, and environmental science. Significance of Microbial Genome Editing Microorganisms serve as vital components in numerous biological processes, acting as workhorses for fermentation, bioremediation, and the production of pharmaceuticals. The abili…
Innovation in biotechnology has reached new heights with the advancement of microbial genome editing services. These services enable researchers and industries to modify the genetic makeup of microorganisms, such as bacteria and yeast, with remarkable precision. As a result, microbial genome editing has become a cornerstone in various fields, including agriculture, medicine, and environmental science. Significance of Microbial Genome Editing Microorganisms serve as vital components in numerous biological processes, acting as workhorses for fermentation, bioremediation, and the production of pharmaceuticals. The abili…
30-May-2025
For centuries, scientific publishing has followed the same basic structure. Researchers submit papers to journals, wait months or even years for peer review and face expensive paywalls to share or read findings. Today, a growing movement known as decentralised science, or DeSci, is challenging this outdated model. Philipp Koellinger, CEO and co-founder of open science pioneer DeSci Labs, explains how this new approach is changing science across the globe.
For centuries, scientific publishing has followed the same basic structure. Researchers submit papers to journals, wait months or even years for peer review and face expensive paywalls to share or read findings. Today, a growing movement known as decentralised science, or DeSci, is challenging this outdated model. Philipp Koellinger, CEO a…
For centuries, scientific publishing has followed the same basic structure. Researchers submit papers to journals, wait months or even years for peer review and face expensive paywalls to share or read findings. Today, a growing movement known as decentralised science, or DeSci, is challenging this outdated model. Philipp Koellinger, CEO a…
A group of almost 100 international experts, including three from Aston University, has developed recommendations for good practice in the analysis of oxylipins, fatty molecules which play central roles in human health and disease, using liquid chromatography-mass spectrometry (LC-MS/MS).
Fatty molecules called oxylipins play central roles in human health and disease but analysing them is technically difficult Almost 100 international experts developed recommendations to analyse oxylipins using liquid chromatography-mass spectrometry (LC-MS/MS) Aston Institute for Membrane Excellence’s Professor Corinne Spickett, Dr Irundika Dias and Dr Ivana Milic were amongst the experts consulted. A group of almost 100 international experts, including three from Aston University, has developed rec…
Fatty molecules called oxylipins play central roles in human health and disease but analysing them is technically difficult Almost 100 international experts developed recommendations to analyse oxylipins using liquid chromatography-mass spectrometry (LC-MS/MS) Aston Institute for Membrane Excellence’s Professor Corinne Spickett, Dr Irundika Dias and Dr Ivana Milic were amongst the experts consulted. A group of almost 100 international experts, including three from Aston University, has developed rec…
Chemical sunscreens utilize organic compounds such as avobenzone, homosalate, octisalate, octocrylene, and oxybenzone that absorb UV radiation and convert it to heat.
In an era where skin cancer rates continue to rise globally, the significance of effective sun protection cannot be overstated. Sunscreen cosmetics represent the frontline defense against the sun's harmful ultraviolet radiation, offering a shield that helps prevent not only cosmetic damage like premature aging but also potentially life-threatening conditions. The sunscreen market has evolved dramatically, with products now formulated to address specific skin types, activities, and protection needs. However, the technical terminology found on sunscreen packaging often creates confusion among consumers. This article explores the…
In an era where skin cancer rates continue to rise globally, the significance of effective sun protection cannot be overstated. Sunscreen cosmetics represent the frontline defense against the sun's harmful ultraviolet radiation, offering a shield that helps prevent not only cosmetic damage like premature aging but also potentially life-threatening conditions. The sunscreen market has evolved dramatically, with products now formulated to address specific skin types, activities, and protection needs. However, the technical terminology found on sunscreen packaging often creates confusion among consumers. This article explores the…
The pharmaceutical landscape encompasses a diverse range of API types, each targeting specific health conditions and physiological systems.
Active Pharmaceutical Ingredients (APIs) form the foundation of modern pharmaceuticals, serving as the biologically active components responsible for the therapeutic effects of medications. These crucial compounds undergo rigorous research, development, and manufacturing processes before being integrated into final pharmaceutical formulations. The pharmaceutical landscape encompasses a diverse range of API types, each targeting specific health conditions and physiological systems. Understanding these various categories provides valuable insights into the complexity and sophistication of contemporary medicine and highlights the continuous innovations dri…
Active Pharmaceutical Ingredients (APIs) form the foundation of modern pharmaceuticals, serving as the biologically active components responsible for the therapeutic effects of medications. These crucial compounds undergo rigorous research, development, and manufacturing processes before being integrated into final pharmaceutical formulations. The pharmaceutical landscape encompasses a diverse range of API types, each targeting specific health conditions and physiological systems. Understanding these various categories provides valuable insights into the complexity and sophistication of contemporary medicine and highlights the continuous innovations dri…
Biocatalysis employs biological systems, particularly enzymes, to catalyse chemical reactions. These natural catalysts facilitate chemical transformations on organic compounds, providing significant advantages over traditional methods.
Biocatalysis employs biological systems, particularly enzymes, to catalyse chemical reactions. These natural catalysts facilitate chemical transformations on organic compounds, providing significant advantages over traditional methods. Challenges with Traditional Catalytic Systems Traditional catalysts, based on inorganic and organic molecules, are essential in synthesizing complex molecules but face several challenges: Cost: Catalysts can be very expensive to purchase. Maintenance: They often need to be removed from a product and cleaned. Specificity:…
Biocatalysis employs biological systems, particularly enzymes, to catalyse chemical reactions. These natural catalysts facilitate chemical transformations on organic compounds, providing significant advantages over traditional methods. Challenges with Traditional Catalytic Systems Traditional catalysts, based on inorganic and organic molecules, are essential in synthesizing complex molecules but face several challenges: Cost: Catalysts can be very expensive to purchase. Maintenance: They often need to be removed from a product and cleaned. Specificity:…
14-May-2025
The field of protein production is seeing widespread adoption of cell-free protein synthesis (CFPS), revolutionising the industry with its high-throughput and cost-effective capabilities. This innovative method has created new opportunities for synthesising proteins, especially those that are challenging to produce in living cells. But what makes cell-free protein synthesis so advantageous, and why is it the preferred choice for high-throughput screening and directed evolution?
The Benefits of Cell-Free Protein Synthesis in Protein Production The field of protein production is seeing widespread adoption of cell-free protein synthesis (CFPS), revolutionising the industry with its high-throughput and cost-effective capabilities. This innovative method has created new opportunities f…
The Benefits of Cell-Free Protein Synthesis in Protein Production The field of protein production is seeing widespread adoption of cell-free protein synthesis (CFPS), revolutionising the industry with its high-throughput and cost-effective capabilities. This innovative method has created new opportunities f…
Quality Assurance (QA) means putting a formal system in place with the help of plans, policies, and procedures to ensure that products are manufactured and tested accurately in compliance with relevant standards.
Quality Control is a set of procedures and activities that ensures the quality, safety, and efficacy of products by sampling, testing analyzing raw materials, in-process samples, and finished products during different stages of production.
In the pharmaceutical and life sciences industries, the terms Quality Assurance (QA) and Quality Control (QC) are often used interchangeably, but they represent two distinct and critical functions within a Quality Management System (QMS). Misunderstanding the difference between QA and QC can lead to inefficiencies, complian…
In the pharmaceutical and life sciences industries, the terms Quality Assurance (QA) and Quality Control (QC) are often used interchangeably, but they represent two distinct and critical functions within a Quality Management System (QMS). Misunderstanding the difference between QA and QC can lead to inefficiencies, complian…
Martin Kesselgruber, VP Global Project Management at Bachem, offers insights on the key measures for companies to consider for successful project outcomes
Robust project management is essential in any manufacturing business, particularly where strict regulations and complex production processes require maximum alignment between all involved functions. As a Contract Development and Manufacturing Organisation (CDMO), Bachem has developed unique expertise in project management approaches and systems. CDMOs play a crucial role in supplying Active Pharmaceutical Ingredients (APIs) to biotech and pharmaceutical companies, involving all required steps like raw materials management, process development and validation, production, purification, and delivery. To ensure efficiency and…
Robust project management is essential in any manufacturing business, particularly where strict regulations and complex production processes require maximum alignment between all involved functions. As a Contract Development and Manufacturing Organisation (CDMO), Bachem has developed unique expertise in project management approaches and systems. CDMOs play a crucial role in supplying Active Pharmaceutical Ingredients (APIs) to biotech and pharmaceutical companies, involving all required steps like raw materials management, process development and validation, production, purification, and delivery. To ensure efficiency and…
Nitrogen compounds are a crucial aspect of pharmaceutical chemistry, particularly in the development of antibiotics. Their unique chemical properties, including the ability to form multiple hydrogen bonds and engage in various interactions, make them indispensable in the fight against bacterial infections.
This article delves into the application of nitrogen compounds in antibiotic research and development, illustrating how they influence antibiotic efficacy. Fundamental Properties of Nitrogen Compounds Nitrogen compounds are defined as chemical substances containing nitrogen atoms within their molecular structure. In drug chemistry, these compounds are renowned for their diverse properties that directly impact their biological interactions. The presence of nitrogen affec…
This article delves into the application of nitrogen compounds in antibiotic research and development, illustrating how they influence antibiotic efficacy. Fundamental Properties of Nitrogen Compounds Nitrogen compounds are defined as chemical substances containing nitrogen atoms within their molecular structure. In drug chemistry, these compounds are renowned for their diverse properties that directly impact their biological interactions. The presence of nitrogen affec…
This article explores the types, functions, and significance of polymer additives in various applications.
Polymer additives play a critical role in the processing and performance of polymer materials. These additives are substances included in the polymer matrix during manufacturing to modify the material's physical properties, improve processing qualities, or enhance performance characteristics. Types of Polymer Additives Polymer additives can be classified into several categories based on their functions: Plasticizers: These additives increase the flexibility, workability, and plasticity of polymers. Commonly used in polyvinyl chloride (PVC) formulations, plasticizers allow for easier processing while reducing brittleness. Stabilizers: Stabilizers protect po…
Polymer additives play a critical role in the processing and performance of polymer materials. These additives are substances included in the polymer matrix during manufacturing to modify the material's physical properties, improve processing qualities, or enhance performance characteristics. Types of Polymer Additives Polymer additives can be classified into several categories based on their functions: Plasticizers: These additives increase the flexibility, workability, and plasticity of polymers. Commonly used in polyvinyl chloride (PVC) formulations, plasticizers allow for easier processing while reducing brittleness. Stabilizers: Stabilizers protect po…
