Research and development - Articles

Explore the top clinical trial solutions for modern trials, including EDC, CTMS, RTSM, eCOA, ePRO, eTMF, and AI-powered tools that help sponsors and CROs improve efficiency, data quality, and trial oversight.
This guide compares the top clinical trial solution providers in 2026, including enterprise leaders like Oracle Health Sciences, Medidata, and Veeva Systems, alongside rapidly growing AI-focused platforms such as Clinion and specialized vendors like Clario and Signant Health. Clinical trials are no longer powered by standalone Electronic Data Capture (EDC) systems alone. In 2026, sponsors and CROs are looking for unified eClinical ecosystems that combine EDC, RTSM, CTMS, eTMF, eConsent, and AI-driven automation. The shift toward decentralized trials and real-time data revie…

Real-world evidence is increasingly demonstrating tobacco harm reduction (THR) in action, so why do many public health bodies and regulators remain sceptical? Joe Thompson, Group Science & Regulatory Affairs Director at Imperial Brands, builds on his panel contribution at the World Nicotine Congress to examine the arguments.
Real-world evidence is increasingly demonstrating tobacco harm reduction (THR) in action, so why do many public health bodies and regulators remain sceptical? Joe Thompson, Group Science & Regulatory Affairs Director at Imperial Brands, builds on his panel contribution at the World Nicotine Congress to examine the arguments. Increasingly, it’s real-world data – not just laboratory and clinical testing – that’s complementing the existing evidence base and helping fil…

Gene and cell therapy is moving fast – and in a clear direction. Programs are pushing toward more complex payloads, virus-free engineering, and manufacturing models that can scale from early research to late-stage clinical supply without exploding timelines or cost of goods. At the same time, the field is confronting familiar constraints: viral-vector bottlenecks, payload limits, and the risk that DNA elements that are useful for bacterial cloning can become unwanted baggage when the DNA is used as starting material for therapeutics...
Gene and cell therapy is moving fast – and in a clear direction. Programs are pushing toward more complex payloads, virus-free engineering, and manufacturing models that can scale from early research to late-stage clinical supply without exploding timelines o…

The audits are the main regulatory tool for many industries especially the medical device and pharmaceutical sector. The audits, whether they are internal, vendor-based, or regulatory, should be done by organizations to show that they comply with the strict quality standards of cGMP, QMS, and CAPA. The article exposes the ins and outs of audits, regulatory inspections, and compliance requirements, with a special emphasis on FDA inspections and the QSIT (Quality System Inspection Technique) approach.
Introduction to Audits In the fields of pharmaceuticals and medical devices where regulation is imposed, compliance with the quality standards set by the authorities is vital for the protection of the products from dangerous effects and ensuring therapeutic efficiency. Audits form an integral pa…

Explore the top EDC platforms for clinical trials in 2026. Features, strengths, limitations, and how to choose the right platform for your study.
Choosing the right EDC (electronic data capture) platform is critical for sponsors, CROs, and clinical operations teams running modern trials. In 2026, clinical trial software solutions have become increasingly sophisticated, ranging from enterprise suites to lean, budget-friendly tools. These clinical trial data capture software systems replace legacy tools with secure, centralized, and modern systems, ensuring 21 CFR Part 11 audit trails, encryption, and compliance with ICH-GCP guidelines. EDC systems are central to modern clinical trials, enhancing data accuracy while enabling real-time monitoring, faster database locks, and streamlined wor…

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Introduction The rapid growth of technology-driven customer service makes AI Call Centres among the essentials of modern business today. With the aid of a virtual AI Call Assistant, an organization can do almost all tasks of AI Phone Call concerning customer service and essentially high-quality. An application in a virtual AI Receptionist helps in reducing costs, speeding processes, and allowing personnel to attend queries only an actual human figure can answer. In other words, intelligent systems integrated with automation revolutionizes how organizations go about achieving that cost-effec…

Aston University and Midlands-based company PFE Medical are teaming up to create biodegradable gloves made from food waste for use in the NHS.
Knowledge Transfer Partnership between Aston University and PFE Medical to develop a biodegradable clinical glove from food waste The gloves will provide a low-cost, convenient and sustainable alternative to the 1.4bn disposable gloves used in the NHS each year The innovation will reduce clinical waste and costs and help the NHS reach its net zero goals. Aston University and Midlands-based company PFE Medical are teaming up to create biodegradable gloves made from food waste for use in the NHS. They will offer a low-cost, convenient alternative to disposable gloves without compromising patient safety. More than 1.4bn disposable gloves are used by t…

In today’s biotech landscape, quality is essential. Good Manufacturing Practice (GMP) guidelines are the cornerstone of safe, effective, and consistent pharmaceutical production. For therapeutics based on peptides or oligonucleotides (TIDES), many of which treat complex or life-threatening conditions, GMP compliance is a foundational element of regulatory approval and patient trust.
Growing Importance of Peptide & Oligonucleotide Therapeutics Peptides and oligonucleotides are transforming modern medicine. Peptide-based drugs have become the fastest-growing segment of chemically synthesized therapeutics, with over 80 approved worldwide, more than 200 in clinical development, and hundreds in preclinical stages (Rossino et al., 2023). Oligonucleotide-based therapies have also seen signi…

Histopathological grading examines tissue samples under a microscope to determine the severity of most cancers, and AI can complement human efforts to improve grading. To evaluate AI performance, experts should use a standardized dataset, preprocess AI algorithms against the foundation, and more.
Pharmaceutical experts have been upgrading pathological analysis methods for years. Uncovering secrets under microscopes requires years of training and extensive data, particularly for samples containing cancerous cells. Grading each prognosis demands precision that can be enhanced with the help of artificial intelligence.  What Is Histopathological Grading? Histopathological grading examines tissue samples under a microscope to determine the severity of most cancers. It observes trends like c…

Artificial intelligence (AI) is rapidly transforming biomarker discovery by unlocking insights from vast and complex datasets. Hurdle recently reviewed how revolutionary this technology could be, while also highlighting the potential hurdles that still stand in the way of its translation into the clinic.
Artificial intelligence (AI) is rapidly transforming biomarker discovery by unlocking insights from vast and complex datasets. Hurdle recently reviewed how revolutionary this technology could be, while also highlighting the potential hurdles that still stand in the way of its translation into the clinic.   The Explosion of Data: Bigger, Broader, More ComplexLarge cohort studies are no longer a curiosity; they’re foundational. Crucially, these cohorts increasingly link rich electronic h…

The Bachem team share their insights on the evolving relationship between pharma companies and CDMOs
Outsourcing plays a critical role in modern drug development and manufacturing – one which has gained increasing importance in recent years. The continued rise in demand for complex modalities, such as peptides and oligonucleotides, and increased pressures on time-to-market, have amplified the need for external partnerships and collaboration to ensure supply of crucial medication to patients. As a result, pharmaceutical outsourcing is moving away from transactional, fee-for-service arrangements, toward long-term, strategic partnerships. With a greater need to ensure delivery of medication to patients, industry players are promoting enhanced collaboration, through acknowledging shared goals a…

The global Penicillin Active Pharmaceutical Ingredients (API) market was valued at USD 2.95 billion in 2023 and is projected to reach USD 4.79 billion by 2032, growing at a CAGR of 5.6%. This growth is driven by the increasing demand for antibiotics, advancements in manufacturing technologies, and the expansion of healthcare infrastructure in emerging economies. The report provides an in-depth analysis of market trends, key players, and regional dynamics, offering valuable insights for stakeholders in the pharmaceutical industry.
The Penicillin Active Pharmaceutical Ingredients (APIs) market represents a cornerstone of the global pharmaceutical industry, providing the essential building blocks for antibiotics that combat a wide range of bacterial infections. With its critical role in health…

As cannabis research continues to progress, increasing attention is being given to two promising compounds, cannabigerol (CBG) and its precursor, cannabigerolic acid (CBG-A). Often overshadowed by the more widely recognised cannabinoids THC and CBD, these non-psychoactive compounds are now being explored for their therapeutic potential.
As cannabis research continues to progress, increasing attention is being given to two promising compounds, cannabigerol (CBG) and its precursor, cannabigerolic acid (CBG-A). Often overshadowed by the more widely recognised cannabinoids THC and CBD, these non-psychoactive compounds are now being explored for their therapeutic potential. Broughton, a leading UK-based contract research organisation, explores early research on the potential of these cannabinoid…

The global Ambulatory EHR Market is projected to grow from USD 6.1 billion in 2023 to USD 10.5 billion by 2032 at a CAGR of 6.3%. Explore market size, major regional trends, deployment shifts toward cloud/web-based models, leading vendors, and what to expect through 2032 in this comprehensive analysis guided by Ameco Research.
In recent years, the healthcare industry has undergone rapid digital transformation. Among its key components is the adoption of Ambulatory EHR (Electronic Health Records in outpatient / ambulatory care settings) systems. These solutions are essential tools for physician offices, specialty clinics, and other outpatient facilities to maintain accurate patient histories, manage clinical workflows, enable remote care protocols, and meet regulatory requirements. As pressu…

Multiple System Atrophy Therapeutics is an evolving field focused on treating a rare neurodegenerative disease with no cure. This article examines the Multiple System Atrophy Therapeutics Market, its size, growth drivers, recent product development, regional trends, key players, and what lies ahead up to 2033—based largely on the report by Acumen Research And Consulting.
What is Multiple System Atrophy and the Role of Therapeutics Multiple System Atrophy (MSA) is a progressive, rare neurodegenerative disorder adversely affecting the autonomic nervous system, movement, balance, coordination, and various bodily functions. Patients experience tremor, parkinsonian symptoms, cerebellar dysfunction, autonomic dysregulation (blood pressure, bladder control), and rapidly declining ability to perfor…

The CBH Biospecimen Marketplace is an online biobank and biorepository built for teams who need human biological samples with audit-ready documentation and dependable logistics. Our continuously curated biological specimen inventory exceeds a quarter of a million active units and spans serum, plasma, whole blood, PBMC for research, urine samples, cerebrospinal fluid (CSF), saliva, stool/feces/faeces, swab samples, and human tissue (FFPE and frozen). You can search, filter, compare, and order human biospecimens for research, development, and production—not only RUO feasibility. What differentiates the platform is scientific traceability: standardized preanalytics, transparent biospecimen data, and route-proven cold-chain shipping.
  What Counts as a Human Biological Specimen? Human biol…

Nutrigenomics is reshaping how we understand the connection between genes and diet. This article explores how DNA insights can guide personalized nutrition, improve long-term wellness strategies, and empower individuals to make informed lifestyle choices. With privacy-first, on-device processing, Noorns provides a secure and innovative approach to DNA-based health insights, bridging science and everyday health.
Nutrigenomics, the study of how our genes interact with diet, is emerging as one of the most promising areas in personalized health. Genetic variations can influence how we metabolize nutrients, respond to supplements, and manage risks for chronic conditions. Understanding these patterns opens new opportunities for preventative care, optimized wellness strategies, and more targeted i…

Analytical method development and validation are essential for CRDMO success, ensuring accurate, reliable, and regulatory-compliant results from R&D to GMP manufacturing. Pharmaffiliates integrates ISO 17025-accredited lab services into its CRDMO model, offering capabilities like HPLC, LC-MS/MS, impurity profiling, stability testing, and method transfer. Validated methods enable consistent batch quality, faster scale-up, and streamlined regulatory compliance, helping clients accelerate drug development with confidence.
The Role of Analytical Method Development in CRDMO Success Why Analytics Is a Pillar of Pharmaceutical Development In today’s pharmaceutical environment, where compliance and speed-to-market are paramount, analytical method development and validation play a foun…

The United States Food and Drug Administration’s (FDA’s) Accelerated Approval (AA) pathway, initially established in 1992 during the HIV/AIDS epidemic to provide faster access to life-saving treatments, has been instrumental in expediting access to therapies for serious and life-threatening conditions. It is particularly significant in therapeutic areas, such as rare diseases, where surrogate or intermediate clinical endpoints may be necessary due to limited patient populations or slow disease progression. While this approach has encouraged innovation, it has also raised concerns about drugs staying on the market without confirmed evidence of their effectiveness.
The United States Food and Drug Administration’s (FDA’s) Accelerated Approval (AA) pathway, initially established in 1992 during…