Articles
Probiotics are living microorganisms that are known to confer health benefits on the host when consumed in adequate amounts. They are typically found in fermented foods like yogurt, kefir, and pickles.
Probiotics are living microorganisms that are known to confer health benefits on the host when consumed in adequate amounts. They are typically found in fermented foods like yogurt, kefir, and pickles. Nowadays, due to the growing interest in gut health and the microbiome, probiotics have become popular dietary supplements in the form of capsules, tablets, powders, and drinks. Companies like Alfa Chemistry have been at the forefront of developing high-quality probiotic supplements that aim to optimize gut health and support overall well-being. These supplements contain specific strains o…
Probiotics are living microorganisms that are known to confer health benefits on the host when consumed in adequate amounts. They are typically found in fermented foods like yogurt, kefir, and pickles. Nowadays, due to the growing interest in gut health and the microbiome, probiotics have become popular dietary supplements in the form of capsules, tablets, powders, and drinks. Companies like Alfa Chemistry have been at the forefront of developing high-quality probiotic supplements that aim to optimize gut health and support overall well-being. These supplements contain specific strains o…
16-Aug-2024
Chemists play a crucial role in the life sciences industry by contributing to various aspects of research and development. In drug development, chemists are responsible for designing, synthesising, and analysing new drugs. They collaborate with scientists and technicians to conduct experiments, analyse data, and develop new products or technologies in laboratories.
Chemists play a crucial role in the life sciences industry by contributing to various aspects of research and development. In drug development, chemists are responsible for designing, synthesising, and analysing new drugs. They collaborate with scientists and technicians to conduct experiments, analyse data, and develop new products or technologies in laboratories. Read the full article on PharmiWeb.Jobs.
Chemists play a crucial role in the life sciences industry by contributing to various aspects of research and development. In drug development, chemists are responsible for designing, synthesising, and analysing new drugs. They collaborate with scientists and technicians to conduct experiments, analyse data, and develop new products or technologies in laboratories. Read the full article on PharmiWeb.Jobs.
Amplicon-based approaches may be preferable for their simplified workflow and smaller amounts of required DNA. However, hybridization-based strategies are less likely to miss mutations and also perform better with respect to sequencing complexity and uniformity of coverage. There are also differences with regard to sample requirements, sensitivity, workflow, cost, etc.
The introduction of next-generation sequencing (NGS) has provided us with a broader and deeper perspective of genetic research. While whole‐genome sequencing may capture all possible mutations, targeted NGS that focuses on specific regions of the genome remains a widely-used, efficient, and cost-effective strategy, which offers a focused approach of the most phenotype‐altering regions for NGS. T…
The introduction of next-generation sequencing (NGS) has provided us with a broader and deeper perspective of genetic research. While whole‐genome sequencing may capture all possible mutations, targeted NGS that focuses on specific regions of the genome remains a widely-used, efficient, and cost-effective strategy, which offers a focused approach of the most phenotype‐altering regions for NGS. T…
Chimeric RNA, also known as fusion RNA, refers to RNA molecules that are formed as a result of the fusion of two or more different RNA transcripts. Chimeric RNA, a unique class of RNA molecules formed through various molecular mechanisms, such as trans-splicing, read-through transcription, and fusion genes. These hybrid transcripts play a significant role in diverse biological processes and have gained substantial attention in recent years.
What is Chimeric RNA? Chimeric RNA, also known as fusion RNA, refers to RNA molecules that are formed as a result of the fusion of two or more different RNA transcripts. Chimeric RNA, a unique class of RNA molecules formed through various molecular mechanisms, such as trans-splicing, read-through transcription, and fusion genes. These hybrid transcripts…
What is Chimeric RNA? Chimeric RNA, also known as fusion RNA, refers to RNA molecules that are formed as a result of the fusion of two or more different RNA transcripts. Chimeric RNA, a unique class of RNA molecules formed through various molecular mechanisms, such as trans-splicing, read-through transcription, and fusion genes. These hybrid transcripts…
RNA splicing is a post-transcriptional modification process that occurs in eukaryotic cells. When a gene is transcribed, the initial RNA product is called pre-mRNA, which contains both coding regions (exons) and non-coding regions (introns).
What Is RNA Splicing? RNA splicing is a post-transcriptional modification process that occurs in eukaryotic cells. When a gene is transcribed, the initial RNA product is called pre-mRNA, which contains both coding regions (exons) and non-coding regions (introns). RNA splicing removes the introns from the pre-mRNA molecule and joins together the exons to form a mature mRNA molecule that can be translated into protein. What Is the Process of RNA Splicing? The process of splicing is carried out by a complex called the spliceosome, which is composed…
What Is RNA Splicing? RNA splicing is a post-transcriptional modification process that occurs in eukaryotic cells. When a gene is transcribed, the initial RNA product is called pre-mRNA, which contains both coding regions (exons) and non-coding regions (introns). RNA splicing removes the introns from the pre-mRNA molecule and joins together the exons to form a mature mRNA molecule that can be translated into protein. What Is the Process of RNA Splicing? The process of splicing is carried out by a complex called the spliceosome, which is composed…
24-Jul-2024
Rare DNA changes within a population of cells are the first manifestations of mutations, which are the fuel for evolution. The research of genomic variation between species and individual organisms has been revolutionized by next-generation sequencing (NGS) technologies.
Introduction to Variant Analysis Rare DNA changes within a population of cells are the first manifestations of mutations, which are the fuel for evolution. The research of genomic variation between species and individual organisms has been revolutionized by next-generation sequencing (NGS) technologies. Variant detection and analysis refer to the sequencing and difference analysis of a genome from an individual or a population of a species using high-throughput sequencing technology in order to acquire a large p…
Introduction to Variant Analysis Rare DNA changes within a population of cells are the first manifestations of mutations, which are the fuel for evolution. The research of genomic variation between species and individual organisms has been revolutionized by next-generation sequencing (NGS) technologies. Variant detection and analysis refer to the sequencing and difference analysis of a genome from an individual or a population of a species using high-throughput sequencing technology in order to acquire a large p…
CRISPR-Cas9 is a gene editing technology that has changed the landscape of biological research. It stands for Clustered Regularly Interspaced Short Palindromic Repeats and CRISPR-Associated Protein 9.
What is CRISPR-Cas9? CRISPR-Cas9 is a gene editing technology that has changed the landscape of biological research. It stands for Clustered Regularly Interspaced Short Palindromic Repeats and CRISPR-Associated Protein 9. CRISPR-Cas9 uses a two-component system consisting of a guide RNA (gRNA) and a Cas9 protein. The gRNA is designed to complement specific target sequences in the genome to guide the Cas9 protein to the desired location. Once the Cas9 protein reaches the target site, it causes a double-strand break in the DNA helix, which initiates a cellular repair process that can lead t…
What is CRISPR-Cas9? CRISPR-Cas9 is a gene editing technology that has changed the landscape of biological research. It stands for Clustered Regularly Interspaced Short Palindromic Repeats and CRISPR-Associated Protein 9. CRISPR-Cas9 uses a two-component system consisting of a guide RNA (gRNA) and a Cas9 protein. The gRNA is designed to complement specific target sequences in the genome to guide the Cas9 protein to the desired location. Once the Cas9 protein reaches the target site, it causes a double-strand break in the DNA helix, which initiates a cellular repair process that can lead t…
Carbon Quantum Dots range from simple organic molecules to complex functionalized materials and can be synthesized in various ways, making them an attractive candidate for a wide range of applications.
Carbon quantum dots (CQDs) are a newly discovered class of quantum materials that have generated significant interest in both academia and industry. With a diameter below 10 nm, they are a type of carbon nanoparticle that exhibits remarkable physical and chemical properties. They range from simple organic molecules to complex functionalized materials and can be synthesized in various ways, making them an attractive candidate for a wide range of applications. Introduction of Carbon Quantum Dots Carbon quantum dots are zero-dimensional nanoparticles made of sp2-hybridized carbon atoms. The…
Carbon quantum dots (CQDs) are a newly discovered class of quantum materials that have generated significant interest in both academia and industry. With a diameter below 10 nm, they are a type of carbon nanoparticle that exhibits remarkable physical and chemical properties. They range from simple organic molecules to complex functionalized materials and can be synthesized in various ways, making them an attractive candidate for a wide range of applications. Introduction of Carbon Quantum Dots Carbon quantum dots are zero-dimensional nanoparticles made of sp2-hybridized carbon atoms. The…
The future of drug discovery and pharmaceutical research and development is being reshaped by artificial intelligence (AI), heralding a new era of speed, efficiency, and precision. AI’s potential to accelerate drug development, from molecular prediction to optimised design and improved clinical trials, promises to significantly cut costs and time-to-market for new medications.
The future of drug discovery and pharmaceutical research and development is being reshaped by artificial intelligence (AI), heralding a new era of speed, efficiency, and precision. AI’s potential to accelerate drug development, from molecular prediction to optimised design and improved clinical trials, promises to significantly cut costs and time-to-market for new medications. In this article, we explore the transform…
The future of drug discovery and pharmaceutical research and development is being reshaped by artificial intelligence (AI), heralding a new era of speed, efficiency, and precision. AI’s potential to accelerate drug development, from molecular prediction to optimised design and improved clinical trials, promises to significantly cut costs and time-to-market for new medications. In this article, we explore the transform…
Nanoformulation leverages nanotechnology to create drug delivery systems that can improve the efficacy, reduce side effects, and precisely target disease sites.
Introduction In the ever-evolving landscape of drug delivery systems, nanoformulation stands out as a revolutionary approach. Nanoformulation leverages nanotechnology to create drug delivery systems that can improve the efficacy, reduce side effects, and precisely target disease sites. This cutting-edge technology has garnered significant attention from researchers and pharmaceutical companies alike, due to its potential to transform the way medications are formulated and administered. The nanoformulation platform embodies this innovative stride by providing a robust framework for engineering and delivering drugs at the nanosca…
Introduction In the ever-evolving landscape of drug delivery systems, nanoformulation stands out as a revolutionary approach. Nanoformulation leverages nanotechnology to create drug delivery systems that can improve the efficacy, reduce side effects, and precisely target disease sites. This cutting-edge technology has garnered significant attention from researchers and pharmaceutical companies alike, due to its potential to transform the way medications are formulated and administered. The nanoformulation platform embodies this innovative stride by providing a robust framework for engineering and delivering drugs at the nanosca…
24-Jul-2024
Digital twins are a virtual replica of a physical object, system, or process. In the pharmaceutical industry, digital twins are especially useful in drug discovery and production, but they still have much unrealized potential.
Could digital twins permanently change the pharmaceutical sector? While this cutting-edge technology already has applications in the clinical and drug production fields, it needs to be utilized more. Here’s how industry professionals can use this revolutionary technology. What Is a Digital Twin? A digital twin is a virtual replica of a physical object, individual, system or process. It replicates the asset’s form, features and functionality to produce a digitalized, three-dimensional copy that is basically indistinguishable from its real-world counterpart. The main co…
Could digital twins permanently change the pharmaceutical sector? While this cutting-edge technology already has applications in the clinical and drug production fields, it needs to be utilized more. Here’s how industry professionals can use this revolutionary technology. What Is a Digital Twin? A digital twin is a virtual replica of a physical object, individual, system or process. It replicates the asset’s form, features and functionality to produce a digitalized, three-dimensional copy that is basically indistinguishable from its real-world counterpart. The main co…
24-Jul-2024
According to a new report published today, urgent action is required to develop skills and retrain staff in the UK’s pharmaceutical sector to take advantage of a predicted boom in RNA medicines and treatments.
It highlights that the workforce could need at least 150 future capabilities to meet RNA vaccine and treatment demand. This includes developing novel equipment and reagents to increase efficiencies within RNA therapeutics manufacturing. The report also highlights the need to enhance technical and digital capabilities so companies can scale up manufacturing. The report urges the industry to plan for the future roles, novel equipment and capabilities needed to develop and provide innovative treatments and medicines. Meanwhile, the industry s…
It highlights that the workforce could need at least 150 future capabilities to meet RNA vaccine and treatment demand. This includes developing novel equipment and reagents to increase efficiencies within RNA therapeutics manufacturing. The report also highlights the need to enhance technical and digital capabilities so companies can scale up manufacturing. The report urges the industry to plan for the future roles, novel equipment and capabilities needed to develop and provide innovative treatments and medicines. Meanwhile, the industry s…
The healthcare landscape is in the process of being dramatically transformed by the advent of digital health technology, driving innovation and revolutionizing healthcare delivery. Artificial Intelligence (AI) and Machine Learning (ML) are particularly poised to impact several healthcare domains, from diagnostics and treatment to patient monitoring and management.
The healthcare landscape is in the process of being dramatically transformed by the advent of digital health technology, driving innovation and revolutionizing healthcare delivery. Artificial Intelligence (AI) and Machine Learning (ML) are particularly poised to impact several healthcare domains, from diagnostics and treatment to patient monitoring and management. These technologies hold significant promise, especially in underfun…
The healthcare landscape is in the process of being dramatically transformed by the advent of digital health technology, driving innovation and revolutionizing healthcare delivery. Artificial Intelligence (AI) and Machine Learning (ML) are particularly poised to impact several healthcare domains, from diagnostics and treatment to patient monitoring and management. These technologies hold significant promise, especially in underfun…
09-Aug-2024
Bioinformatics is an interdisciplinary field that integrates computer science, mathematics, statistics, and biology to manage and analyse biological data. This field is crucial to the life sciences industry for its role in understanding complex biological processes, leading to significant advances in drug discovery, genetic research, and personalised medicine.
Bioinformatics is an interdisciplinary field that integrates computer science, mathematics, statistics, and biology to manage and analyse biological data. This field is crucial to the life sciences industry for its role in understanding complex biological processes, leading to significant advances in drug discovery, genetic research, and personalised medicine. The role of bioinformaticians is expansive and vital. They develop algorith…
Bioinformatics is an interdisciplinary field that integrates computer science, mathematics, statistics, and biology to manage and analyse biological data. This field is crucial to the life sciences industry for its role in understanding complex biological processes, leading to significant advances in drug discovery, genetic research, and personalised medicine. The role of bioinformaticians is expansive and vital. They develop algorith…
If new digital capabilities and top-notch data are critical to process efficiency and competitive advantage, it makes no sense to leave validation (proof that they fulfil what’s required) until the latter stages of the project lifecycle, say Ulrich Lein and Stefani Godoy Herrera of MAIN5.
Any systems relevant to GxP (‘good practices’) must be validated as fulfilling their intended purpose. Yet, too often, computer system validation (CSV) or assurance (CSA) is treated as a distracting compliance exercise, when it could be used to ensure strategic benefits – such as seamless data sharing, and repurposing of data across functional boundaries. The alternative is projects not delivering and having to be reworked, at great expense and delay. Ultimately, it could mean patients failing to gain prom…
Any systems relevant to GxP (‘good practices’) must be validated as fulfilling their intended purpose. Yet, too often, computer system validation (CSV) or assurance (CSA) is treated as a distracting compliance exercise, when it could be used to ensure strategic benefits – such as seamless data sharing, and repurposing of data across functional boundaries. The alternative is projects not delivering and having to be reworked, at great expense and delay. Ultimately, it could mean patients failing to gain prom…
Pharmacovigilance, specifically adverse event case intake, is a prime candidate for disruption by AI. Here, ArisGlobal’s Emmanuel Belabe explores how far Generative AI and Large Language Models have come in enabling human-like decision-making and processing, and the broader opportunity beyond.
Pharmacovigilance processes are designed to uphold the safety of marketed human medinical products over time, once authorised for patient consumption, but as the ocean of available data continues to rise in volume, the task of discerning and acting on important signals is becoming ever harder. It’s odd then that approaches to post-market Safety monitoring have changed little in decades First there’s the increasing array of formats through which cases come to light, not to mention the proliferating ran…
Pharmacovigilance processes are designed to uphold the safety of marketed human medinical products over time, once authorised for patient consumption, but as the ocean of available data continues to rise in volume, the task of discerning and acting on important signals is becoming ever harder. It’s odd then that approaches to post-market Safety monitoring have changed little in decades First there’s the increasing array of formats through which cases come to light, not to mention the proliferating ran…
Recent top global hires for large-cap, mid-cap, and public companies, covering a broad range of disciplines and sectors across Life Sciences, Health, and Tech.
CEO/ C-suite/ Board Function Focus area Location CEO Medical equipment (publicly listed) US/ UK Chief Development Officer Biotech (publicly listed) Europe Chief R&D Officer Mental healthcare (publicly listed) US Chief Technology Officer AI-enabled drug discovery (publicly listed) Europe Chief, Operations & Supply Chain Speciality pharma (mid-cap) Europe Board Director Biopharma (publicly listed) US Board Director Novel enzymes (publicly listed) Nordics Group General Counsel Animal health (large-cap) Europe Commercial / Fun…
CEO/ C-suite/ Board Function Focus area Location CEO Medical equipment (publicly listed) US/ UK Chief Development Officer Biotech (publicly listed) Europe Chief R&D Officer Mental healthcare (publicly listed) US Chief Technology Officer AI-enabled drug discovery (publicly listed) Europe Chief, Operations & Supply Chain Speciality pharma (mid-cap) Europe Board Director Biopharma (publicly listed) US Board Director Novel enzymes (publicly listed) Nordics Group General Counsel Animal health (large-cap) Europe Commercial / Fun…
Inpatient services refer to medical treatments and care that require a patient to be admitted to a hospital or healthcare facility for at least one night. These services encompass a wide range of medical care, including surgeries, childbirth, severe illnesses, and chronic disease management. Inpatient services are a critical component of the healthcare system, ensuring patients receive comprehensive care and monitoring when outpatient services are insufficient.
The rising incidence of chronic diseases such as diabetes, cardiovascular diseases, and cancer has significantly contributed to the growth of the inpatient services market. As these conditions often require complex and prolonged treatments, the demand for inpatient services has surged, leading to the expansion of healthcare facilities and the adoption of advanced medical technologies.
11-Jul-2024
The development of antibody cocktails is a complex and meticulous process that requires a deep understanding of target biology, antibody engineering, and combinatorial approaches.
What is Antibody Cocktail Therapy? Antibody cocktail therapy is a treatment that mixes two or more monoclonal antibodies together. By combining the properties of different antibodies, this therapy can target multiple targets simultaneously, thereby enhancing the effectiveness of treatment and reducing the development of drug resistance. Antibody cocktail therapy has broad application prospects in fields such as tumors and autoimmune diseases. How to Develop Antibody Cocktail Therapy? The development of antibody cocktails is a complex and meticulous process that requires a deep understanding of target biology, anti…
What is Antibody Cocktail Therapy? Antibody cocktail therapy is a treatment that mixes two or more monoclonal antibodies together. By combining the properties of different antibodies, this therapy can target multiple targets simultaneously, thereby enhancing the effectiveness of treatment and reducing the development of drug resistance. Antibody cocktail therapy has broad application prospects in fields such as tumors and autoimmune diseases. How to Develop Antibody Cocktail Therapy? The development of antibody cocktails is a complex and meticulous process that requires a deep understanding of target biology, anti…
We are delighted to announce that the second edition of our popular introductory guide: ‘Market access stakeholders and processes for medical devices in key European markets’ is now available. Our market access experts have updated the guide with European market insights for 2024/25, along with a new section covering the US market.
An introductory guide to market access stakeholders and processes for medical devices in key European markets and the USA In this introductory guide, our Global market access experts provide an overview of the commercial launch landscape for medical devices in the USA and key European healthcare systems. We highlight the differences between selected markets and provide a go-to guide for those looking to bring medical device innovations to the…
An introductory guide to market access stakeholders and processes for medical devices in key European markets and the USA In this introductory guide, our Global market access experts provide an overview of the commercial launch landscape for medical devices in the USA and key European healthcare systems. We highlight the differences between selected markets and provide a go-to guide for those looking to bring medical device innovations to the…
