Articles

Calum Jones (Associate Director – Health Economics) shares his experience of speaking at the 2024 HTAi Annual Meeting. Calum participated in the panel discussion: ‘Surrogate Endpoints in Health Technology Assessment (HTA): From Trials to Economic Evaluations
  Calum Jones (Associate Director – Health Economics) shares his experience of speaking at the 2024 HTAi Annual Meeting. Calum participated in the panel discussion: ‘Surrogate Endpoints in Health Technology Assessment (HTA): From Trials to Economic Evaluations’. On 18th June, I had the distinct pleasure of participating in an expert panel at the HTAi annual meeting held in the picturesque city of Seville, Spain. The session, titled ‘Surrogate Endpoints in Health Technology Assessment (HTA): From Trials to Economi…

Native Bacillus licheniformis protease stands out as a significant player in the realm of enzymatic solutions, offering a wide array of benefits and applications due to its unique properties.
Enzymes play a pivotal role in various industrial processes, catalyzing biochemical reactions with precision and efficiency. Among the diverse classes of enzymes, proteases are essential components with the ability to break down proteins into amino acids, enabling various biological functions and industrial applications. Native Bacillus licheniformis protease stands out as a significant player in the realm of enzymatic solutions, offering a wide array of benefits and applications due to its unique properties.   Understanding Bacillus licheniformis Protease Bacillus licheniformis, a common Gram-pos…

Enzymes are the fundamental building blocks of life, playing crucial roles in countless biological processes. One such remarkable enzyme is Native Porcine Prolidase, which has garnered significant attention in the scientific community due to its unique properties and diverse applications. In this article, we will delve into the intricacies of this remarkable enzyme, exploring its structure, function, physiological importance, and the ways in which it is leveraged in various industries.
Enzymes are the fundamental building blocks of life, playing crucial roles in countless biological processes. One such remarkable enzyme is Native Porcine Prolidase, which has garnered significant attention in the scientific community due to its unique properties and diverse applications. In this article, we…

Bile, a complex fluid produced by the liver and stored in the gallbladder, plays a crucial role in the digestion and absorption of fats, fat-soluble vitamins, and other essential nutrients. Ox bile extract powder, derived from the bile of oxen, is a natural supplement that has garnered significant interest in the scientific and healthcare communities for its versatile physiological functions and potential therapeutic applications.
Bile, a complex fluid produced by the liver and stored in the gallbladder, plays a crucial role in the digestion and absorption of fats, fat-soluble vitamins, and other essential nutrients. Ox bile extract powder, derived from the bile of oxen, is a natural supplement that has garnered significant interest in the scientific and healthcare communities for its versa…

Leading Swiss peptide and oligonucleotide manufacturer Bachem explains the considerations behind choosing between peptide synthesis methodologies
The demand for the manufacturing of polypeptides has radically increased since the recent introduction of new diabetes, obesity and cardiovascular disease peptide drugs. Consequently, peptide API manufacturing has seen a radical industrial intensification in line with increased commercialization to drive efficiency, improve quality and lower cost.   To achieve this at a commercial scale, peptide APIs can be produced through two principle processes: synthetic or recombinant.   Both methodologies offer unique advantages, with their own respective drawbacks. Thus, it’s vital to ensure that stakeholders are fully aware of the limits and st…

Lab-made mini-organs are revolutionizing the future of life science research with their remarkable potential. These tiny, three-dimensional structures, grown from stem cells, closely resemble real human organs. The uses of mini-organs span across various subjects, including disease modeling and drug development, offering unprecedented insights and innovative solutions to some of healthcare’s most challenging problems.
Lab-made mini-organs are revolutionizing the future of life science research with their remarkable potential. These tiny, three-dimensional structures, grown from stem cells, closely resemble real human organs. The uses of mini-organs span across various subjects, including disease modeling and drug development, offering unprecedented insights and innovative solutions to some…

Scientists have predicted that the first person who will live to 150 has already been born.1 While this number may sound far-fetched, researchers have developed several interventions to extend the human lifespan. Innovations such as artificial intelligence, stem cell therapy, precision medicine, and telemedicine are changing how healthcare providers diagnose and treat illnesses, ultimately increasing the average life expectancy. But how exactly is technology helping us live longer?
Scientists have predicted that the first person who will live to 150 has already been born.1 While this number may sound far-fetched, researchers have developed several interventions to extend the human lifespan. Innovations such as artificial intelligence, stem cell therapy, precision medicine, and telemedicine…

There is constant innovation across industries as time passes. While other sectors are vital, life science has seen critical advancements globally. How are researchers able to achieve these fantastic breakthroughs? Consider the intersection of life sciences and technology. Here’s what you need to know about the various life sciences and their recent innovations.
There is constant innovation across industries as time passes. While other sectors are vital, life science has seen critical advancements globally. How are researchers able to achieve these fantastic breakthroughs? Consider the intersection of life sciences and technology. Here’s what you need to know about the various life sciences and their recent innovations. Why Innovations Are Critical to Life Science Research You expect parts…

The design and synthesis of hydrophobic amino acids hold immense significance in various scientific domains, including drug development, biochemistry, and materials science.
Hydrophobic amino acids are vital components in the realm of protein structure and function. While hydrophilic amino acids establish interactions with water molecules in the cellular environment, hydrophobic amino acids tend to congregate in the interior of proteins, contributing to their three-dimensional fold and stability.    The synthesis of hydrophobic amino acids involves intricate chemical processes aimed at constructing these organic molecules with specific structural characteristics while ensuring high purity and yield. One common method for synthesizing hydrophobic amino acids is through solid-phase…

Antibody-drug conjugates (ADCs) have emerged as a promising class of targeted therapeutics in the field of oncology.
These molecules combine the specificity of monoclonal antibodies with the cytotoxic potency of small molecule drugs, thereby enabling precise delivery of potent anticancer agents to tumor cells while minimizing harm to healthy tissues. The efficacy of ADCs hinges on a delicate interplay between various components, with the payload playing a crucial role in determining the therapeutic potential of these complex molecules.   ADC payloads, also known as cytotoxic or chemotherapeutic agents, are the active drug molecules that are conjugated to the antibody component of an ADC. These payloads are designed to induce cell death within targeted cancer cells, thereby achieving th…

RNA synthesis is a fundamental technique in molecular biology that allows researchers to design and create specific RNA molecules tailored to their experimental needs.
These custom RNA molecules play crucial roles in a wide range of applications, including gene expression studies, functional genomics, and RNA interference experiments. The process of custom RNA synthesis involves the production of RNA molecules with precise sequences and modifications, enabling researchers to investigate various biological processes with high specificity and efficiency.   In RNA synthesis, there are two main methods commonly used: chemical synthesis and enzymatic synthesis. Custom chemical synthesis involves the step-by-step assembly of RNA molecules using nucleotide building blocks and chemic…

PG is commonly used as an excipient in a variety of drugs and is also approved for use in food and cosmetics.
About Propylene Glycol Propylene glycol (PG) is a clear, odorless, and viscous liquid that is miscible with water and many organic solvents. It is a small molecule that is structurally different and unrelated to PEG, despite a similar name. PG is commonly used as an excipient in a variety of drugs and is also approved for use in food and cosmetics. In addition, it has a wide range of other practical applications, such as antifreeze agent, cutting fluid, and as an additive to latex paints and coatings to increase freeze-thaw capabilities. Propylene Glycol as An Excipient Excipients are essential supports for active ingredients in drugs, vaccines and other products, contributing…

In an ever-evolving field like medical writing, versatility is not just a skill – it’s a necessity. As the demands of the healthcare sector grow increasingly complex, you should be looking for new ways to diversify your portfolio and effectively demonstrate your range of skills and depth of knowledge.
In an ever-evolving field like medical writing, versatility is not just a skill – it’s a necessity. As the demands of the healthcare sector grow increasingly complex, you should be looking for new ways to diversify your portfolio and effectively demonstrate your range of skills and depth of knowledge. A well-crafted, diverse portfolio will showcase your competence across various sub-disciplines, demonstrating your versatility and positioning you for success in the competitive 2024 job market. …

Mtech Access are now part of Petauri. This marks a significant and exciting milestone in our journey, and aligns with our commitment to partnering with industry to bring life-enhancing technologies to market, providing more patient choice and meeting the needs of the healthcare environment.
What this means for our clients: Enhanced services: This strategic move will allow us to offer greater breadth and depth of technical and consulting experience, as well as market coverage for our clients. Continuity and stability: The quality of work and client service that you have come to expect, along with your current projects and relationships, will remain unchanged. Innovative solutions: Leveraging the strengths of the Petauri group, we will build on our commitment to growth and inn…

Personalised benefits packages are tailored to meet the individual preferences and needs of each employee, replacing standard benefits packages that are offered to all employees. According to a 2022 survey, 50% of workers would be prepared to accept a pay reduction in exchange for more tailored benefits, and 74% said they would work harder for an employer that provided benefits that support individual needs.
Personalised benefits packages are tailored to meet the individual preferences and needs of each employee, replacing standard benefits packages that are offered to all employees. According to a 2022 survey, 50% of workers would be prepared to accept a pay reduction in exchange for more tailored benefits, and 74% said they would work harder for an employer that provided benefits that sup…

The growing number of investments in T-cell transfer looks promising for market growth. Several new clinical trial initiations for T-cell therapies have risen exponentially over the years. The lack of manufacturing capacity for commercial-scale gene therapy production and viral-vector manufacturing has led to the opening of a wide number of CDMOs and in-house facilities for gene therapy manufacturing. This is anticipated to build profitable opportunities for the players.
The need to treat rare genetic diseases, enhance quality of life, and unlock the next wave of treatment innovations is projected to promote the growth of the gene therapy market.  Various universities and institutes are home to a broad-ranging portfolio of products in the pipeline. In addition, several researchers are…

Both liquid and semi-solid formulations require a series of steps during the preparation process to ensure the quality and stability of the final product.
Similarities and Differences Between Liquid Formulation and Semi-solid Formulation Both liquid and semi-solid formulations require a series of steps during the preparation process to ensure the quality and stability of the final product. The similarities and differences between them are mainly reflected in the following aspects: Overall process: The preparation process of liquid preparations is usually more straightforward, which involves dissolving the drug in a solvent and completing the steps of mixing and stirring. The preparation process of semi-solid preparations requires more steps, such as mixing, heating, cooling, stir…

Global vascular patches market is projected to witness a CAGR of 6.97% during the forecast period 2024–2031F
Global vascular patches market is projected to witness a CAGR of 6.97% during the forecast period 2024–2031F, growing from USD 507.68 million in 2023 to USD 870.12 million in 2031F. The market has experienced significant growth in recent years and is expected to maintain a strong pace of expansion in the coming years. Vascular patches are used to treat aneurysms, arterial stenosis, and undesirable blood clots, in addition to reconstructing tissue or arteries in cardiovascular illnesses. Heart arteries (coronary arterial bypass), kidneys, legs (femoropopliteal bypass), and the abdominal aorta are the usual surgical sites. The increasing global prevalence of cardiovascular disorders is…

Transitioning from a Medical Doctor's traditional path to the world of a Freelance MedComms Consultant has been exciting and seasoned with opportunities. This shift has allowed me to leverage my extensive international medical training, teaching, and biomedical research experience and introduced me to a world where flexibility, continuous learning, and building long-standing client relationships are paramount.
Transitioning from a Medical Doctor's traditional path to the world of a Freelance MedComms Consultant has been exciting and seasoned with opportunities. This shift has allowed me to leverage my extensive international medical training, teaching, and biomedical research experience and introduced me to a world where flexibility, continuous learning, and building long-standing client re…

Different techniques have been developed to functionalize nanotubes, including covalent and non-covalent approaches.
Nanotubes, with their unique properties and structure, have revolutionized various fields of science and technology. Over the past few decades, tremendous efforts have been made to functionalize nanotubes, unlocking their true potential for a wide range of applications. Understanding Functionalization of Nanotubes Functionalization refers to the process of modifying the surface properties of nanotubes, enabling them to interact with specific molecules or materials. This modification plays a crucial role in tailoring the physical and chemical properties of nanotubes, making them suitable for a variety of applications. Different techniques have been developed to functionalize…