Articles

Global vascular patches market is projected to witness a CAGR of 6.97% during the forecast period 2024–2031F
Global vascular patches market is projected to witness a CAGR of 6.97% during the forecast period 2024–2031F, growing from USD 507.68 million in 2023 to USD 870.12 million in 2031F. The market has experienced significant growth in recent years and is expected to maintain a strong pace of expansion in the coming years. Vascular patches are used to treat aneurysms, arterial stenosis, and undesirable blood clots, in addition to reconstructing tissue or arteries in cardiovascular illnesses. Heart arteries (coronary arterial bypass), kidneys, legs (femoropopliteal bypass), and the abdominal aorta are the usual surgical sites. The increasing global prevalence of cardiovascular disorders is…

Transitioning from a Medical Doctor's traditional path to the world of a Freelance MedComms Consultant has been exciting and seasoned with opportunities. This shift has allowed me to leverage my extensive international medical training, teaching, and biomedical research experience and introduced me to a world where flexibility, continuous learning, and building long-standing client relationships are paramount.
Transitioning from a Medical Doctor's traditional path to the world of a Freelance MedComms Consultant has been exciting and seasoned with opportunities. This shift has allowed me to leverage my extensive international medical training, teaching, and biomedical research experience and introduced me to a world where flexibility, continuous learning, and building long-standing client re…

Different techniques have been developed to functionalize nanotubes, including covalent and non-covalent approaches.
Nanotubes, with their unique properties and structure, have revolutionized various fields of science and technology. Over the past few decades, tremendous efforts have been made to functionalize nanotubes, unlocking their true potential for a wide range of applications. Understanding Functionalization of Nanotubes Functionalization refers to the process of modifying the surface properties of nanotubes, enabling them to interact with specific molecules or materials. This modification plays a crucial role in tailoring the physical and chemical properties of nanotubes, making them suitable for a variety of applications. Different techniques have been developed to functionalize…

In the recruitment sector, having a specialist by your side makes all the difference. Our dedicated team combines industry savvy with the skills and a personalised touch to deliver results that matter. Find out more!
At Amanda Wright, we're proud to be not just another recruitment agency. We're your strategic partner in the fast-paced, ever-changing world of Recruitment to Recruitment (Rec2Rec). Our mission? To bridge the gap between extraordinary talent and the agencies that need them.  In the recruitment sector, having a specialist by your side makes all the difference. Our dedicated team combines industry savvy with the skills and a personalised touch to deliver results that matter.      Our team is highly experienced and passionate about Rec2Rec. This passion drives…

A recent poll conducted among clinical trial professionals has highlighted the most significant trends expected to transform the industry over the next five years
A recent poll conducted among industry professionals reveals significant insights into the evolving landscape of clinical trials. With 70% of respondents identifying increased use of AI and machine learning (ML) as the biggest trend, it is clear that integrating advanced technologies will play a pivotal role in shaping the future of clinical trials. Other notable trends include the rise of decentralized trials (14%), enhanced patient engagement tools (13%), and regulatory harmonization (4%). The Future of Clinical Trials: Key Trends As the clinical trials industry evolves, it faces numerous challenges, including data management in…

In a snap analysis of the social media conversations of healthcare professionals following the news that the NHS has launched its world-first personalised cancer vaccination programme, Creation Healthcare found that, while the response was overwhelmingly positive, some apprehension remained that vaccine hesitancy and anti-vax sentiment could hinder uptake among patients.
Healthcare professionals across the globe have reacted “overwhelmingly positively” to news that thousands of NHS patients in England will be fast-tracked onto a world-first personalised cancer vaccine scheme.  In a snap analysis following the breaking news, leading digital insights consultancy Creation Healthcare found that online healthcare professionals heralded the vaccine as a “game changer”, although som…

Babies who cannot access breast milk are one step closer to benefitting from a pioneering microbiome supplement that will provide them with the crucial microbes required for healthy development.
That’s after the healthcare startup BoobyBiome collaborated with technology innovation centre, CPI. to scale-up their cutting-edge bacterial supplement.  The organisations have announced that the collaboration has brought the supplement closer to commercial reality.  The supplement contains live bacteria identified and sourced from the microbiomes of donated breast milk that can boost the immune systems of babies whose mothers cannot breastfeed.  The product can be added to formula milk, or breast milk for babies who require additional support to improve gut health and develop their…

The collaboration between the Centre for Process Innovation (CPI), academia, and industry leaders within pharma and digital could help medicines reach patients up to a year faster (30 April 2024).
The collaboration will develop a working model of a cloud-first manufacturing facility that will use technologies such as artificial intelligence (AI), machine learning and the Internet of Things (IoT) to accelerate the speed at which new medicines are made.  Using these technologies in pharma could lead to patients gaining faster access to innovative treatments and could reduce operational costs for manufacturers by up to 30 per cent.  Alongside cost reduction, digital manufacturing technologies also allow greater agility to scale production and meet changing demand, with som…

Non-coding RNAs (ncRNAs) are RNA molecules that cannot be translated into proteins. ncRNAs are found in a wide range of organisms and serve a number of roles. Transfer RNAs (tRNAs) are traditional noncoding RNAs (ncRNAs) that transform genetic information from messenger RNA (mRNA) to amino acid sequence information in nascent proteins.
Non-coding RNAs (ncRNAs) are RNA molecules that cannot be translated into proteins. ncRNAs are found in a wide range of organisms and serve a number of roles. Transfer RNAs (tRNAs) are traditional noncoding RNAs (ncRNAs) that transform genetic information from messenger RNA (mRNA) to amino acid sequence information in nascent proteins.   The anticodon loop of tRNAs may be precisely spliced into tRNA halves under the influence of sex hormone, hypoxia…

With the development of next-generation sequencing (NGS) technologies and new sequencers, the exponential growth of biological information generated by the scientific community has brought benefits as well as new challenges to researchers. In the era of big data, the field of bioinformatics has made significant progress in the analysis and interpretation of biological data. Therefore, there is a need to develop computational techniques and tools for effective data analysis and visualization to help understand biological processes.
With the development of next-generation sequencing (NGS) technologies and new sequencers, the exponential growth of biological information generated by the scientific community has brought benefits as well as new challenges to researchers. In the era of big data,…

Bioinformaticsis a rapidly evolving field filled with a plethora of tools for processing and manipulating next-generation sequencing (NGS) data. The performance of NGS alignment tools continues to improve, but it now takes more time to sort aligned data than to align it. SAMtools and sambamba are two commonly used tools for sorting binary alignment map (BAM) files.
Bioinformaticsis a rapidly evolving field filled with a plethora of tools for processing and manipulating next-generation sequencing (NGS) data. The performance of NGS alignment tools continues to improve, but it now takes more time to sort aligned data than to align it. SAMtools and sambamba are two commonly used tools for sorting binary alignment map (BAM) files.   SAMtools SAMtools, developed by the 1000 Genomes…

Whole genome bisulfite sequencing (WGBS) converts unmethylated cytosine (C) to thymine (T) with the bisulfite treatment on genomic DNA. Subsequently, whole genome resequencing of the treated DNA and comparison with the reference genome were performed to achieve single-base resolution and high-accuracy methylation level analysis from the genomic level.
DNA methylation is an important component of epigenetics and plays an important role in maintaining normal cellular function, genetic imprinting, embryonic development, and human tumorigenesis. Whole genome bisulfite sequencing (WGBS) converts unmethylated cytosine (C) to thymine (T) with the bisulfite treatment on genomic DNA. Subsequently, whole genome resequencing of the treated DNA and comparison with the…

RNA methylation stands as a pivotal focus within the realm of epigenetics. With a repertoire exceeding 100 distinct modifications, notable examples include methylation, hydroxymethylation, and acetylation. Among these, m6A stands as the most prevalent methylation modification on RNA, averaging 1 to 3 m6A modifications per transcript.
RNA methylation stands as a pivotal focus within the realm of epigenetics. With a repertoire exceeding 100 distinct modifications, notable examples include methylation, hydroxymethylation, and acetylation. Among these, m6A stands as the most prevalent methylation modification on RNA, averaging 1 to 3 m6A modifications per transcript. Ubiquitous across eukaryotes, encompassing mammals, insects, plants, yeast, and select viruses, m6A occurs not only on mRNA…

Santosh Sahu, CEO and Founder of Charac, discusses why England's 'Pharmacy First' is vital in improving patient access to healthcare, but will only succeed if pharmacies adapt.
At the end of January, England put into practice a new ‘Pharmacy First’ approach to healthcare, encouraging patients to seek treatment from their pharmacist rather than a GP for minor illnesses such as sore throats or shingles - set against the dire reality of one in 20 patients currently waiting at least four weeks to see a GP. The implementation of Pharmacy First is designed to cut down wait times, giving patients quicker access to quality healthcare. However, the government’s proposed plans have not entirely accounted for additional support required by community pharmacies. The Pharmacy Landscape Although this fra…

GCP courses are some of the most widespread online trainings. So how do we choose where to register and which course to purchase?
Online training courses become more and more popular. The pharmaceutical industry also follows this trend. GCP courses are some of the most widespread online trainings. So how do we choose where to register and which course to purchase? There are several important points we need to consider before making our decision: The first one and probably most important is accreditation. What does an accredited course mean? meets national quality assurance requirements. meets an established industry, enterprise, educational, legislative or community need provides appropriate competency outcomes and a basis for assessment It is always better to have a course that is accred…

Lipids are the basic substances that make up biological membranes. Through lipid-lipid interactions and interactions between lipids and other biomolecules, a complex network of lipid metabolism is formed, which is involved in a large number of life activities. By studying lipid extracts, information about the lipidome can be obtained. Lipidomics studies lipids in organisms at a systematic level, revealing their interactions and interactions with other biomolecules.
Lipids are the basic substances that make up biological membranes. Through lipid-lipid interactions and interactions between lipids and other biomolecules, a complex network of lipid metabolism is formed, which is involved in a large number of life activities. By studying lipid extracts, information about the lipidome can be obta…

Trillions of microorganisms live in the gastrointestinal tract, far outnumbering the body's own cells. The intestinal flora is involved in many physiological and pathological processes in the host, including digestion and absorption of food, metabolism of certain nutrients and pharmaceutical compounds, development of host immunity, intestinal inflammatory states, and more. Dysbiosis of the intestinal flora is associated with a variety of human metabolic diseases, such as obesity, diabetes mellitus, and nonalcoholic fatty liver disease.
Trillions of microorganisms live in the gastrointestinal tract, far outnumbering the body's own cells. The intestinal flora is involved in many physiological and pathological processes in the host, including digestion and absorption of food, metabolism of cer…

Metabolomics is a quantitative study of the dynamic patterns of changes in the types and amounts of endogenous small molecule metabolites (generally MW < 1,000) in organisms under the influence of endogenous and exogenous factors (e.g. genetic variation, disease attack, drug intervention, environmental changes, etc.) and their association with physiological and pathological changes.
Metabolomics is a quantitative study of the dynamic patterns of changes in the types and amounts of endogenous small molecule metabolites (generally MW < 1,000) in organisms under the influence of endogenous and exogenous factors (e.g. genetic variation, disease attack, drug intervention, environmental changes, etc.) and their association with physiological and pathological changes.   Pharmacometabo…

Cancer is a complex disease that involves a delicate interplay between the tumor cells and the host immune system. Cytokines play a critical role in this interplay, mediating the communication between different cells of the immune system and modulating immune responses. As such, cytokine profiling is becoming increasingly important in the study of cancer and is being used to support research, diagnosis, and treatment decisions.
Cancer is a complex disease that involves a delicate interplay between the tumor cells and the host immune system. Cytokines play a critical role in this interplay, mediating the communication between different cells of the immune system and modulating immune responses. As such, cytokine profiling is becoming increasingly important in the study of cancer and is being…

Cancer is a complex disease that involves a delicate interplay between the tumor cells and the host immune system. Cytokines play a critical role in this interplay, mediating the communication between different cells of the immune system and modulating immune responses. As such, cytokine profiling is becoming increasingly important in the study of cancer and is being used to support research, diagnosis, and treatment decisions.
Cancer is a complex disease that involves a delicate interplay between the tumor cells and the host immune system. Cytokines play a critical role in this interplay, mediating the communication between different cells of the immune system and modulating immune responses. As such, cytokine profiling is becoming increasingly important in the study of cancer and is being…