Clinical research - Articles
Bringing top talent to your Clinical Research Organisation (CRO) can be a challenge, regardless of how long you’ve been working in recruitment. In a job market that’s remained highly competitive, standing out as an employer of choice and finding new ways to locate and engage your target audience of talent is becoming harder than ever. In this article, we’ve outlined 6 key steps to take when searching for CRAs to help you refine your recruitment strategy.
Bringing top talent to your Clinical Research Organisation (CRO) can be a challenge, regardless of how long you’ve been working in recruitment. In a job market that’s remained highly competitive, standing out as an employer of choice and finding new ways to locate and engage your target audience of talent is becoming harder than ever. In th…
Bringing top talent to your Clinical Research Organisation (CRO) can be a challenge, regardless of how long you’ve been working in recruitment. In a job market that’s remained highly competitive, standing out as an employer of choice and finding new ways to locate and engage your target audience of talent is becoming harder than ever. In th…
03-Mar-2023
Also known as Clinical Trial Managers or Clinical Study Managers, Clinical Project Managers (CPM) are responsible for planning and coordinating clinical research projects. They direct the activities of workers engaged in clinical research projects to ensure compliance with protocols and overall clinical objectives.
Also known as Clinical Trial Managers or Clinical Study Managers, Clinical Project Managers (CPM) are responsible for planning and coordinating clinical research projects. They direct the activities of workers engaged in clinical research projects to ensure compliance with protocols and overall clinical objectives. What are the Main Responsibilities of a CPM? The responsibilities of a CPM may vary, but often include: Maintaining required records of study activity, including case…
Also known as Clinical Trial Managers or Clinical Study Managers, Clinical Project Managers (CPM) are responsible for planning and coordinating clinical research projects. They direct the activities of workers engaged in clinical research projects to ensure compliance with protocols and overall clinical objectives. What are the Main Responsibilities of a CPM? The responsibilities of a CPM may vary, but often include: Maintaining required records of study activity, including case…
Bachem is a leading, innovation-driven company specialising in the development and manufacture of peptides and oligonucleotides. With 50 years of experience, Bachem provides products for research, clinical development and commercial application to pharmaceutical and biotechnology companies worldwide and offers a comprehensive range of services. Bachem operates internationally, with headquarters in Switzerland and locations in Europe, the US and Asia. The company is listed on the SIX Swiss Exchange.
Oligonucleotides are short, single or double-stranded fragments of DNA or RNA that can be used for therapeutic purposes. Originally, there was an emphasis on using this new drug modality for treating rare diseases, yet they have also shown great potential to be used for more common diseases. …
Oligonucleotides are short, single or double-stranded fragments of DNA or RNA that can be used for therapeutic purposes. Originally, there was an emphasis on using this new drug modality for treating rare diseases, yet they have also shown great potential to be used for more common diseases. …
ICH Q3D presents major challenges to testing and risk assessments associated with meeting current rigorous limits for specific components to assess patient risk. The probability that sure elemental impurities area unit gift in a very healthful product ought to be determined through a legitimate risk assessment.
The mission of the International Council for Harmonisation of Technical needs for prescription drugs for Human Use (ICH) is to make sure safe, effective, and high-quality medicines area units are developed and distributed. This is often accomplished by making worldwide harmonization. Harmonization achievements within the quality space include: Essential milestones like the conduct of stability studies Process relevant thresholds for impurities testing A lot of versatile approaches t…
The mission of the International Council for Harmonisation of Technical needs for prescription drugs for Human Use (ICH) is to make sure safe, effective, and high-quality medicines area units are developed and distributed. This is often accomplished by making worldwide harmonization. Harmonization achievements within the quality space include: Essential milestones like the conduct of stability studies Process relevant thresholds for impurities testing A lot of versatile approaches t…
27-Jan-2023
If you’re just starting your career in Clinical Research, trying to understand all of the acronyms used in various roles can be confusing. To help, we’ve put together this list of 100 acronyms used in Clinical Research for you to know.
If you’re just starting your career in Clinical Research, trying to understand all of the acronyms used in various roles can be confusing. To help, we’ve put together this list of 100 acronyms used in Clinical Research for you to know. You can also browse the latest Clinical Research jobs on PharmiWeb.Jobs here. Don’t forget to create an account and upload your CV to help recruiters find you! ADR: Adverse Drug Reaction AE: Adverse Event ALCOA: Attributable, Legible, Contemporaneous, Original, Accurate API: Active Pharmaceutical Ingredient / Application Progr…
If you’re just starting your career in Clinical Research, trying to understand all of the acronyms used in various roles can be confusing. To help, we’ve put together this list of 100 acronyms used in Clinical Research for you to know. You can also browse the latest Clinical Research jobs on PharmiWeb.Jobs here. Don’t forget to create an account and upload your CV to help recruiters find you! ADR: Adverse Drug Reaction AE: Adverse Event ALCOA: Attributable, Legible, Contemporaneous, Original, Accurate API: Active Pharmaceutical Ingredient / Application Progr…
The recombinant cell culture supplements market is expected to grow at a CAGR of 10.8% during the forecast period of 2022 to 2030.
A recent report issued by Reports & Insights titled “Recombinant Cell Culture Supplements Market: Opportunity Analysis and Future Assessment 2022-2030” outlines the market size, potential and deep understanding of the statistics geared towards the development of the respective market in an absolute meticulous and thorough manner. The base year considered for the study is 2021, and the market size is projected from 2022-2030. To make it more intriguing, the report further mentions extensive know-how of the market, conceptual framework, and prevailing trends of the market along with the precise textual and graphical representation over the forecast period…
A recent report issued by Reports & Insights titled “Recombinant Cell Culture Supplements Market: Opportunity Analysis and Future Assessment 2022-2030” outlines the market size, potential and deep understanding of the statistics geared towards the development of the respective market in an absolute meticulous and thorough manner. The base year considered for the study is 2021, and the market size is projected from 2022-2030. To make it more intriguing, the report further mentions extensive know-how of the market, conceptual framework, and prevailing trends of the market along with the precise textual and graphical representation over the forecast period…
The Polymerase Chain Reaction (PCR) market is estimated to reach at a value of US$ 5.8 Bn by the end of 2022 and expected to reach at a value of US$ 9.5 Bn by 2030 with a significant CAGR of 6.2%.
The report titled “Polymerase Chain Reaction (PCR) Market: Opportunity Analysis and Future Assessment 2022-2030” recently issued by Reports & Insights has the key objective to provide its readers with an absolute detailed and precise information about the respective market in conjunction with the profound knowledge of the statistics geared towards the development of the respective market. For better understanding of the readers, the report also includes extensive know-how of the market, conceptual framework, and prevailing trends of the market along with the precise textual and graphical repre…
The report titled “Polymerase Chain Reaction (PCR) Market: Opportunity Analysis and Future Assessment 2022-2030” recently issued by Reports & Insights has the key objective to provide its readers with an absolute detailed and precise information about the respective market in conjunction with the profound knowledge of the statistics geared towards the development of the respective market. For better understanding of the readers, the report also includes extensive know-how of the market, conceptual framework, and prevailing trends of the market along with the precise textual and graphical repre…
Global Sperm Bank Market is estimated to reach USD 7.05 billion by 2032 with a CAGR of 3.54%: SPER Market Research
Due to the increasing demand for fertilization methods across the globe, the demand for the sperm banking industry is expected to increase during the forecast period. In addition, increasing infertility cases and the availability of a large number of semen analysis tests are also boosting the growth of the market. However, the high operating costs of sperm banks, negative strategies towards sperm banks and donors, and stringent government regulations in various countries hinder the market growth. In addition, increasing acceptance of single-parent or same-sex families in various countries and societies presents an opportunity for market growth. Sperm Bank Market Overview: Fore…
Due to the increasing demand for fertilization methods across the globe, the demand for the sperm banking industry is expected to increase during the forecast period. In addition, increasing infertility cases and the availability of a large number of semen analysis tests are also boosting the growth of the market. However, the high operating costs of sperm banks, negative strategies towards sperm banks and donors, and stringent government regulations in various countries hinder the market growth. In addition, increasing acceptance of single-parent or same-sex families in various countries and societies presents an opportunity for market growth. Sperm Bank Market Overview: Fore…
In this Article, learn about the key challenges of clinical data management face and see what the future holds for CDMS System
one of the biggest challenges clinical data management faces is the sheer amount of data that needs to be processed. With more and more patient data becoming available, it can be difficult for CDM systems to keep up. In addition, many CDM systems are not user-friendly or interactive, making it difficult for users to get the most out of them. What challenges do clinical data management systems currently face? Clinical Trial Complexity The modern clinical trial design requires real-time data modelling and simulation to provide reliable information that supports faster decision-making and reduces development time, costs, and late-stage research failures. Nowadays, man…
one of the biggest challenges clinical data management faces is the sheer amount of data that needs to be processed. With more and more patient data becoming available, it can be difficult for CDM systems to keep up. In addition, many CDM systems are not user-friendly or interactive, making it difficult for users to get the most out of them. What challenges do clinical data management systems currently face? Clinical Trial Complexity The modern clinical trial design requires real-time data modelling and simulation to provide reliable information that supports faster decision-making and reduces development time, costs, and late-stage research failures. Nowadays, man…
In the drug company trade, with more uncertainties from the method of a research project, project management becomes tougher.
In the drug company trade, with more uncertainties from the method of a research project, project management becomes tougher. Project management within the pharmaceutical trade involves: Scope management Project coming up with, executing, and watching Timeline and budget coming up with and management Stakeholder management Management of regulative and compliance ways Environmental safety Risk management Team management Challenges underlie each of those aspects of project management. The interdependencies between these components create even additional advanced. Whereas the developed product is also effective for the supposed use, it's going to need dangerous chemi…
In the drug company trade, with more uncertainties from the method of a research project, project management becomes tougher. Project management within the pharmaceutical trade involves: Scope management Project coming up with, executing, and watching Timeline and budget coming up with and management Stakeholder management Management of regulative and compliance ways Environmental safety Risk management Team management Challenges underlie each of those aspects of project management. The interdependencies between these components create even additional advanced. Whereas the developed product is also effective for the supposed use, it's going to need dangerous chemi…
A survey of European and US pharma companies’ initial experiences of the EMA’s centralised clinical trials information system (CTIS) has revealed high levels of adoption and widespread recognition of the benefits, according to Arriello’s Kieran O’Donnell and Nicola Kidman.
In the late summer, Arriello commissioned a comprehensive survey of European and US pharma companies’ initial experiences of the EMA’s new centralised clinical trials information system (CTIS). The new platform and portal are designed to streamline the submission, assessment and approval of trials across EU markets, under the new Clinical Trials Regulation (CTR)[1], applicable since the end of January 2022 and mandatory for all new trials from January 31, 2023. Expectations for the new system have been high - if tentative…
In the late summer, Arriello commissioned a comprehensive survey of European and US pharma companies’ initial experiences of the EMA’s new centralised clinical trials information system (CTIS). The new platform and portal are designed to streamline the submission, assessment and approval of trials across EU markets, under the new Clinical Trials Regulation (CTR)[1], applicable since the end of January 2022 and mandatory for all new trials from January 31, 2023. Expectations for the new system have been high - if tentative…
The benefits of digitalisation for clinical trials have become evident during the pandemic, not least for patients. But there are obstacles to overcome, as Dr Rajesh Jain of PharmaLex explains.
Among the myriad transformations forced by COVID-19, decentralised clinical trials may have changed approaches to clinical research for good, bringing a patient-centric approach, reduced costs and faster results. None of this would be possible without digitalisation. While decentralised clinical trials (DCTs), or virtual trials, have been conducted for more than a decade, the pandemic was the catalyst for industry-wide uptake and many sponsors and clinical research organisations (CROs) have chosen to continue with – or adopt – the DCT model. DCTs do bring challenges: investment is required in techn…
Among the myriad transformations forced by COVID-19, decentralised clinical trials may have changed approaches to clinical research for good, bringing a patient-centric approach, reduced costs and faster results. None of this would be possible without digitalisation. While decentralised clinical trials (DCTs), or virtual trials, have been conducted for more than a decade, the pandemic was the catalyst for industry-wide uptake and many sponsors and clinical research organisations (CROs) have chosen to continue with – or adopt – the DCT model. DCTs do bring challenges: investment is required in techn…
Medicines are becoming ever more complex in response to growth in personalised treatments and the development of a wide range of therapeutics to address less common conditions or rare diseases
by Kelly Doering, Sr Director, Industry Marketing, Pharma, AspenTech Medicines are becoming ever more complex in response to growth in personalised treatments and the development of a wide range of therapeutics to address less common conditions or rare diseases. Examples of the latter include small molecules linked to large, perhaps conjugated to a chemotoxic agent for targeted cancer treatment; peptides linked to peptides; oligos linked to molecules that allow for better cell permeability; and lipid-encapsulated molecules that prevent degradation. But it is the market for more personalised medication…
by Kelly Doering, Sr Director, Industry Marketing, Pharma, AspenTech Medicines are becoming ever more complex in response to growth in personalised treatments and the development of a wide range of therapeutics to address less common conditions or rare diseases. Examples of the latter include small molecules linked to large, perhaps conjugated to a chemotoxic agent for targeted cancer treatment; peptides linked to peptides; oligos linked to molecules that allow for better cell permeability; and lipid-encapsulated molecules that prevent degradation. But it is the market for more personalised medication…
05-Aug-2022
With the UK’s Clinical Research industry booming, and with the current job market becoming increasingly candidate-driven, 2022 is an excellent time to be considering a career move within or into Clinical Research. Following on from our previous article outlining 10 Clinical Research career paths, we’ve used Indeed’s Salary Guide to put together this list of the average base salary in the UK for these 13 common Clinical Research roles.
Clinical Research in England alone is worth approximately £2.7 billion a year. In March 2021, the UK government published its vision aimed at propelling the UK Clinical Research industry into the future. 5 key themes underpin this vision: Streamlined, efficient and innovative research Clinical research embedded in the NHS Patient-centred research Research ena…
Clinical Research in England alone is worth approximately £2.7 billion a year. In March 2021, the UK government published its vision aimed at propelling the UK Clinical Research industry into the future. 5 key themes underpin this vision: Streamlined, efficient and innovative research Clinical research embedded in the NHS Patient-centred research Research ena…
25-May-2022
Luminex xMAP technology uses polystyrene microspheres of 5.6 microns in diameter dyed with different ratios of two red-sorting fluorescent dyes to obtain up to 100 fluorescent coded microspheres. Antibody molecules or gene probes for different test items are covalently cross-linked to specific coded microspheres, each of which corresponds to a specific test item.
Principle of Luminex Multiplex Assay Luminex xMAP technology uses polystyrene microspheres of 5.6 microns in diameter dyed with different ratios of two red-sorting fluorescent dyes to obtain up to 100 fluorescent coded microspheres. Antibody molecules or gene probes for different test items are covalently cross-linked to specific coded microspheres, each of which corresponds to a specific test item. The fluorescent coding microsphe…
Principle of Luminex Multiplex Assay Luminex xMAP technology uses polystyrene microspheres of 5.6 microns in diameter dyed with different ratios of two red-sorting fluorescent dyes to obtain up to 100 fluorescent coded microspheres. Antibody molecules or gene probes for different test items are covalently cross-linked to specific coded microspheres, each of which corresponds to a specific test item. The fluorescent coding microsphe…
Clinical research is a process of testing the safety and efficacy of drugs and other medical products. It is done by qualified professionals who are responsible for the design, conduct, analysis, and reporting of clinical trials.
What is Clinical Research? Clinical research is a process of testing the safety and efficacy of drugs and other medical products. It is done by qualified professionals who are responsible for the design, conduct, analysis, and reporting of clinical trials. Clinical research is a process that ensures the safety and efficacy of drugs and other medical products. Clinical research professionals are responsible for designing, conducting, analyzing, and reporting clinical trials that test these products. Pharmacovigilance Courses in Pune. What is the Scope of Clinical Re…
What is Clinical Research? Clinical research is a process of testing the safety and efficacy of drugs and other medical products. It is done by qualified professionals who are responsible for the design, conduct, analysis, and reporting of clinical trials. Clinical research is a process that ensures the safety and efficacy of drugs and other medical products. Clinical research professionals are responsible for designing, conducting, analyzing, and reporting clinical trials that test these products. Pharmacovigilance Courses in Pune. What is the Scope of Clinical Re…
OptraSCAN offers an OS-SiA scanner a next-gen artificial intelligence image slide scanner, driven by artificial intelligence and deep learning concept. The scanner automatically identifies regions to scan and simultaneously analyzes the tissue/cell area being scanned based on tissue morphology and type of biomarker.
Digital pathology has an important role and is increasingly a technological requirement in the diagnostic & scientific labs, medical universities & colleges, research centers, etc. The advantage of whole-slide imaging, the availability of faster networks, and cheaper storage solutions have made it easier for pathologists to manage digital slide images and share them for clinical use. Advances in machine learning have enabled the synergy of artificial intelligence and di…
Digital pathology has an important role and is increasingly a technological requirement in the diagnostic & scientific labs, medical universities & colleges, research centers, etc. The advantage of whole-slide imaging, the availability of faster networks, and cheaper storage solutions have made it easier for pathologists to manage digital slide images and share them for clinical use. Advances in machine learning have enabled the synergy of artificial intelligence and di…
• Following successful appeals by the Merck-Pfizer Alliance, patient groups and healthcare professional organisations, BAVENCIO® (avelumab) has been recommended by NICE as a maintenance treatment option from 7 April 2022 to all eligible patients on the NHS in England, Wales and Northern Ireland[i]
• Avelumab is the first immunotherapy for use as a first-line maintenance treatment for patients with locally advanced or metastatic urothelial carcinoma who have responded to platinum-based chemotherapy
• The approval enables equitable access for all eligible patients in the UK following recommendation by the Scottish Medicines Consortium in August 2021[ii]
Today Merck and Pfizer announce that, following a successful appeal of the prior Final Appraisal Document (FAD), the National Institute f…
Today Merck and Pfizer announce that, following a successful appeal of the prior Final Appraisal Document (FAD), the National Institute f…
Recently, Shionogi Company of Japan reported a non-covalent, non-peptidic, orally bioavailable 3CL protease inhibitor as a clinical candidate for the treatment of COVID-19.
The pathogen causing New Coronavirus pneumonia is a beta genus coronavirus called SARS-CoV-2, which is an RNA virus. After entering cells through the human ACE2 receptor, SARS-CoV-2 translates and expresses the polyprotein pp1a/pp1ab, which is then hydrolyzed by Mpro or 3CLpro or nsp5 to release various nonstructural proteins that are important for virus replication, thus inhibiting the activity of 3CL protease and blocking virus replication. In order to obtain non-covalent 3CL protease inhibitors as clinical candidates quickly, Shionogi performed docking-based virtual screening and biological screening of its in-…
The pathogen causing New Coronavirus pneumonia is a beta genus coronavirus called SARS-CoV-2, which is an RNA virus. After entering cells through the human ACE2 receptor, SARS-CoV-2 translates and expresses the polyprotein pp1a/pp1ab, which is then hydrolyzed by Mpro or 3CLpro or nsp5 to release various nonstructural proteins that are important for virus replication, thus inhibiting the activity of 3CL protease and blocking virus replication. In order to obtain non-covalent 3CL protease inhibitors as clinical candidates quickly, Shionogi performed docking-based virtual screening and biological screening of its in-…
31-Mar-2022
Since Bachem was founded, leadership in the technology and innovation sphere has been the foundation of the business’ success. In order to continually produce high-quality products, taking advantage of new and emerging technologies is key.
This is why Bachem is constantly investing in research to inform and refine their manufacturing processes. This has led to their development of highly optimized tools for one of the key methods for covalent modification of peptides and proteins: the thiol-maleimide reaction.
Since Bachem was founded, leadership in the technology and innovation sphere has been the foundation of the business’ success. In order to continually produce high-quality products, taking advantage of new and emerging technologies is key. This is why Bachem is co…
Since Bachem was founded, leadership in the technology and innovation sphere has been the foundation of the business’ success. In order to continually produce high-quality products, taking advantage of new and emerging technologies is key. This is why Bachem is co…
