Articles

How can you ensure that the market access materials, value proposition and evidence developed by global teams, will resonate for your local audience? In this article, our experts pool their knowledge to share their top tips for successfully taking global materials local.
How can you ensure that the market access materials, value proposition and evidence developed by global teams will resonate for your local audience? National market access teams and other local affiliates are regularly required to adapt global value materials to reflect the nuances and requirements of their local healthcare systems. At Mtech Access, we have a wealth of experience in developing customer communication materials at both global and affiliate level. Leading Pharma and Medtech companies regularly engage…

In today’s fast-paced digital landscape, where smartphones have become an extension of our lives, ensuring that your job application process is mobile friendly is no longer a choice – it’s a strategic imperative. As jobseekers increasingly rely on their mobile devices to search and apply for opportunities on the go, the accessibility and usability of your application process will directly influence your ability to attract top talent.
In today’s fast-paced digital landscape, where smartphones have become an extension of our lives, ensuring that your job application process is mobile friendly is no longer a choice – it’s a strategic imperative. As jobseekers increasingly rely on their mobile devices to search and apply for opportunities on the go, the accessibility and usability of your appli…

Amidst the current initiatives to develop more targeted anti-cancer therapies, immunotherapy has emerged as a highly potent option to selectively eliminate tumor cells with minimal side effects. Immunotherapies essentially make use of the body’s own immune system, or its components, to fight cancer. It is a relatively new concept, currently having achieved pharmacological success with targeted antibody-based therapeutics, including monoclonal and conjugated antibodies.
Amidst the current initiatives to develop more targeted anti-cancer therapies, immunotherapy has emerged as a highly potent option to selectively eliminate tumor cells with minimal side effects. Immunotherapies essentially make use of the body’s own immune system, or its components, to fight cancer. It is a relatively new con…

Dickkopf-1 (DKK1), is a protein that plays a critical role in regulating the Wnt signaling pathway, which is involved in various cellular processes, including cell proliferation, differentiation, and embryonic development. It is an important antagonist of the Wnt pathway, meaning that it inhibits Wnt signaling by binding to specific receptors and preventing the activation of downstream signaling molecules.
Introduction to DKK1 Dickkopf-1 (DKK1), is a protein that plays a critical role in regulating the Wnt signaling pathway, which is involved in various cellular processes, including cell proliferation, differentiation, and embryonic development. It is an important antagonist of the Wnt pathway, meaning that it inhibits Wnt signaling by binding to specific receptors and preventing the acti…

A tumor suppressor gene, also known as anti-onco gene, is an essential component of the body's defense against cancer. It usually facilitates apoptosis. With its absence, the human body will be functioning without its “brake” of cell proliferation. Cells are potent to go under abnormal growth processes and finally lead to tumor/cancer.
About Tumor Suppressor Genes A tumor suppressor gene, also known as anti-onco gene, is an essential component of the body's defense against cancer. It usually facilitates apoptosis. With its absence, the human body will be functioning without its “brake” of cell proliferation. Cells are potent to go under abnormal growth processes and finally lead to tumor/cancer. Here are some key features and functions of tumor suppressor genes: Inhibition of Cell Growth:…

In this article, we delve into 5 essential considerations to help you identify the ideal clients for your organisation, allowing you to successfully achieve your goal of connecting top talent with the organisations that are truly shaping the future of life sciences.
In the dynamic field of life science recruitment, your success as a recruitment agency depends on your ability to identify and collaborate with the right clients. Working with clients who are truly committed to investing in top talent whilst building strong partnerships with you will help you to maximise your chances of success, ultimately improving your industry reputation to both candidates and future clients. In this article, we delve into 5 essential considerations to help you identify the ideal clients for your organisation…

Structured data is the key building block for data exchange that delivers actionable insights. At Amplexor’s recent BE THE EXPERT 2023 global conference in June, Remco Munnik of Iperion - a Deloitte business, cautioned that there is no time to wait for the regulators. Pharma companies need to act now to see the benefits of data-driven process change.
The fact that Life Sciences is now adopting and seeing value in structured data is a huge turning point for the industry, and this acceptance is becoming increasingly palpable. Once companies are able to see beyond the mandatory detail of the regulations that are helping to drive data-oriented process change, their opportunities for transformation of entire functions and their approaches to product tracking and management will broaden and multi…

Homocysteine, an important biomarker in the field of clinical diagnostics, plays a significant role in assessing cardiovascular disease risk, vitamin deficiencies, and genetic disorders. Accurate and sensitive detection of homocysteine levels is crucial for early intervention and personalized patient care. In this article, we delve into the fascinating world of enzymes for producing the Homocysteine Assay Kit, shedding light on the mechanisms behind this powerful diagnostic tool.
Homocysteine, an important biomarker in the field of clinical diagnostics, plays a significant role in assessing cardiovascular disease risk, vitamin deficiencies, and genetic disorders. Accurate and sensitive detection of homocysteine levels is crucial for early intervention and personalized patient care. In this…

In the world of enzymes, one remarkable protein stands out for its exceptional properties and diverse applications – Kex2 Protease from Saccharomyces cerevisiae, Recombinant. This cutting-edge enzyme has garnered significant attention in the biotechnology industry due to its versatile nature and remarkable catalytic abilities. In this article, we will delve into the world of Kex2 Protease, exploring its origins, structure, and remarkable potential across various fields.
Introduction In the world of enzymes, one remarkable protein stands out for its exceptional properties and diverse applications – Kex2 Protease from Saccharomyces cerevisiae, Recombinant. This cutting-edge enzyme has garnered significant attention in the biotechnology industry due to its versatile nature and remarkable catal…

The gut microbiota, a diverse community of microorganisms residing in our gastrointestinal tract, plays a crucial role in maintaining our overall health. Probiotics, live microorganisms with potential health benefits, have garnered significant attention for their ability to promote gut health. In this article, we will delve into the science behind probiotic formulas, exploring their mechanisms of action and scientific evidence supporting their use in maintaining a healthy gut.
The gut microbiota, a diverse community of microorganisms residing in our gastrointestinal tract, plays a crucial role in maintaining our overall health. Probiotics, live microorganisms with potential health benefits, have garnered significant attention for their ability to promote gut health. In this article, we will…

Stable Isotope Labeling by Amino Acids in Cell Culture (SILAC) is a powerful technique that allows for the quantification and characterization of proteins in cells and organisms. It involves the substitution of specific amino acids with their isotopically labeled counterparts in cell culture media. This labeling enables researchers to track and compare protein expression levels, protein-protein interactions, and post-translational modifications, among other biological processes.
Several recent breakthroughs have been made using SILAC, enhancing its applications and expanding its potential. Here are some notable advancements: Proteome-wide analysis: SILAC has been used to perform comprehensive proteome-wide quantification, enabling the identification and quantification of thousands of protei…

Pichia pastoris is a type of yeast that is commonly used in biotechnology for the production of recombinant proteins. It is known for its ability to efficiently produce heterologous proteins with high yields. Pichia pastoris offers several advantages for protein production:
What is pichia pastoris and their functions? Pichia pastoris is a type of yeast that is commonly used in biotechnology for the production of recombinant proteins. It is known for its ability to efficiently produce heterologous proteins with high yields. Pichia pastoris offers several advantages for protein production: Strong and tightly regulated promoters: Pichia pastoris has strong promoters, such as the alcohol oxidase (AOX) promoter, which can drive high levels of protein expression. The AOX promo…

Microsphere technology is at the intersection of cutting-edge disciplines such as materials science, polymer technology, medical technology, and microelectronics.
Microspheres are small spherical entities formed by dispersing or adsorbing drugs in a polymer matrix. The particle size is typically between 1 μm and 250 μm, and the largest can reach more than 800 μm. Microsphere technology is at the intersection of cutting-edge disciplines such as materials science, polymer technology, medical technology, and microelectronics. Once injected into the body, microspheres are gradually degraded in the body, allowing the drug to be released slowly at a certain rate, maintaining the drug concentration in the blood at the site of the lesion, thereby prolonging the half-life of the drug and achieving l…

When it comes to staff welfare and patient care, a healthcare organisation should aim to maximise the things that go right and prevent, mitigate and minimise the things that don’t go as well. Creating a safe, high quality healthcare organisation and service should always be your business’ priority. This will reflect the high levels of compassion and vigilance you have for both your staff and your patients.
When it comes to staff welfare and patient care, a healthcare organisation should aim to maximise the things that go right and prevent, mitigate and minimise the things that don’t go as well. Creating a safe, high quality healthcare organisation and service should always be your business’ priority. This will reflect the high levels of compassion and vigilance you have for both your staff…

In the 2021/22 financial year, NHS Resolution received more than 15,000 negligence claims from patients across the country. So, even though medical professionals strive to provide the safest and most effective treatment as possible, serious allegations can occur from time to time.
In the 2021/22 financial year, NHS Resolution received more than 15,000 negligence claims from patients across the country. So, even though medical professionals strive to provide the safest and most effective treatment as possible, serious allegations can occur from time to time. It is important to recognise that similar situations could happen to your healthcare organisation too. This is why it is always wise to have clinic and medical malpractice insurance in place to protect your business’ finances and clinici…

Here, Shameet Thakkar, founder and managing director of Unimed Procurement Services, an organisation working to improve access to healthcare resources in developing countries, discusses the role of prevention in building healthcare resilience for the benefit of vulnerable populations.
The detrimental issues within health systems in developing countries have become intrinsic to their model, with lack of funding and resources as well as systemic issues causing inequality in access to care. These disparities mean a significant portion of individuals cannot obtain even basic healthcare services or commodities. According to the World Health Organization (WHO), this number equals to at least half of the world’s population. Addressing global health inequities has been a point of focus in the past…

MOFs have been extensively studied and used in the fields of gas storage, molecular separation, catalysis, and sustained drug release during the past 20 years.
Metal organic frameworks (MOFs) are a type of crystalline porous material with a periodic network structure formed by connecting and bridging inorganic metal centers (metal ions or metal clusters) with organic ligands. Because MOFs have many properties such as porosity, large specific surface area, strong designability, multi-metal sites, etc., they have been extensively studied and used in the fields of gas storage, molecular separation, catalysis, and sustained drug release during the past 20 years. Today, electrocatalytic technology plays an important role in the conversion of clean energy and contributes to the development of sus…

The last step of the entire medical billing process is to make sure that the healthcare providers get compensated for their hard-earned services to their fullest potential. For this purpose, the lab billing specialists must follow up with the patients and insurance companies who are behind their dues. Even when required they have to call, email and fax the payers to remind them about their payment regularly.
Healthcare labs play a critical role in the medical field by providing the foundation for critical decisions for important medical procedures. According to a study, healthcare labs contribute to 70% to 80% of critical decisions that are made in a clinical setting or hospital. However, healthcare labs only earn 30% to 40% of revenue comparatively collected by other healthcare settings.&…

Host Cell Residual DNA (rcDNA) refers to fragments of DNA derived from host cells that may be present in biological products. These products must not contain foreign substances, particularly host DNA, to avoid immune rejection and potential threats to life safety. Regulatory agencies worldwide have imposed strict limits on the amount of rcDNA, and various pharmacopoeias have outlined several reliable methods for residual DNA quantification, including threshold methods, hybridization methods, and real-time quantitative PCR.
Host Cell Residual DNA (rcDNA) refers to fragments of DNA derived from host cells that may be present in biological products. These products must not contain foreign substances, particularly host DNA, to avoid immune rejection and potential threats to life safety. Regulat…

The presence of host cell proteins (HCPs) in therapeutic protein drugs can have adverse effects on the production process and product performance. To effectively assess and control the risks associated with HCPs in therapeutic protein products, it is crucial to develop methods that can identify and monitor all HCP components.
The presence of host cell proteins (HCPs) in therapeutic protein drugs can have adverse effects on the production process and product performance. To effectively assess and control the risks associated with HCPs in therapeutic protein products, it is crucial to develop methods that can identify and monitor all HCP components.   Traditional Methods and their Challenges The most commonly used method for HCP assay in therapeutic protein production is the enzyme-linke…