Articles

In the pharmaceutical industry, a vendor refers to an external entity or supplier that provides goods, materials, services, or specialized expertise to pharmaceutical companies. These vendors play a crucial role in supporting various aspects of the pharmaceutical business, ranging from research and development to manufacturing and distribution of medicinal products. They are an integral part of the pharmaceutical supply chain and contribute to the overall success of pharmaceutical operations.
In the pharmaceutical industry, a vendor refers to an external entity or supplier that provides goods, materials, services, or specialized expertise to pharmaceutical companies. These vendors play a crucial role in supporting various aspects of the pharmaceutical business, ranging from research and dev…

During the research and development process of pharmaceutical preparations, comprehensive and reliable interaction studies are essential.
Pharmaceutical formulations consist of active pharmaceutical ingredients (APIs) and excipients. Appropriate excipient selection is critical to the final quality of pharmaceutical products. When designing pharmaceutical preparations, the choice of excipients should not only consider the dosage form factors and excipient functions but also the interaction and compatibility between APIs and excipients. Therefore, during the research and development process of pharmaceutical preparations, comprehensive and reliable interaction studies are essential. These studies not only serve as a foundat…

Post-translational modifications (PTMs) are essential chemical alterations that occur on proteins after their synthesis. These modifications play a crucial role in regulating protein function, cellular signaling, and overall biological processes. To unravel the mysteries of PTMs and understand their functional implications, scientists have developed PTM prediction tools that utilize computational approaches. In this article, we will explore the significance of PTMs, the power of PTM predictions, and their applications in protein research.
Post-translational modifications (PTMs) are essential chemical alterations that occur on proteins after their synthesis. These modifications play a crucial role in regulating protein function, cellular signaling, and overall biological processes. To unrave…

Arterial stiffness is a novel cause of premature heart damage among adolescents, according to a new follow-up study. The study was conducted in collaboration between Texas Children's Hospital and Baylor College of Medicine in the US, the University of Bristol in the UK, the University of Exeter in the UK, and the University of Eastern Finland, and the results were published in Atherosclerosis.
Arterial stiffness is a novel cause of premature heart damage among adolescents, according to a new follow-up study. The study was conducted in collaboration between Texas Children's Hospital and Baylor College of Medicine in the US, the University of Bristol in the UK, the University of Exeter in the UK, and the University of Eastern Finland, and the results were published in Atherosclerosis. Left ve…

In the life science industry, Regulatory Affairs Specialists ensure adherence to intricate regulations and guidelines mandated by regulatory bodies and government agencies. They provide comprehensive oversight throughout the lifecycle of pharmaceuticals, medical devices, biotech products and other healthcare solutions to guarantee products align with standards of safety, efficacy, and quality.
In the life science industry, Regulatory Affairs Specialists ensure adherence to intricate regulations and guidelines mandated by regulatory bodies and government agencies. They provide comprehensive oversight throughout the lifecycle of pharmaceuticals, medical devices, biotech products and other healthcare solutions to guarantee products align with standards of safety, efficacy, and quality. Regulat…

The Karl Fischer method is suitable for the determination of all kinds of substances: chemicals, oils, pharmaceuticals and food, etc.
The Karl Fischer method is an analytical method for the determination of moisture proposed by Karl Fischer in 1935. It is suitable for the determination of all kinds of substances: chemicals, oils, pharmaceuticals and food, etc. At present, Karl Fischer titration has developed into a moisture analysis method widely used in the world. In this article, we will discuss how the Karl Fischer moisture detection test can be applied to complex samples. Insoluble samples In the moisture detection of some samples, laboratory personnel may often encounter that some samples are difficult to dissolve or have poor solubility, resulting in the inability…

Alkaloids possess significant medicinal, pharmaceutical, and ecological importance, making them a subject of extensive research by leading companies.
In the realm of organic chemistry, one class of compounds has captured the scientific community's attention for decades - alkaloids. These naturally occurring compounds are known for their diverse chemical structures and profound biological activities. Many alkaloids have been discovered and studied extensively over the years, with more than 20,000 known alkaloids identified to date. Alkaloids possess significant medicinal, pharmaceutical, and ecological importance, making them a subject of extensive research by leading companies. In this article, we will delve into the intriguing world of alkaloids, exploring their sources, structures, and at…

How can you ensure that the market access materials, value proposition and evidence developed by global teams, will resonate for your local audience? In this article, our experts pool their knowledge to share their top tips for successfully taking global materials local.
How can you ensure that the market access materials, value proposition and evidence developed by global teams will resonate for your local audience? National market access teams and other local affiliates are regularly required to adapt global value materials to reflect the nuances and requirements of their local healthcare systems. At Mtech Access, we have a wealth of experience in developing customer communication materials at both global and affiliate level. Leading Pharma and Medtech companies regularly engage…

In today’s fast-paced digital landscape, where smartphones have become an extension of our lives, ensuring that your job application process is mobile friendly is no longer a choice – it’s a strategic imperative. As jobseekers increasingly rely on their mobile devices to search and apply for opportunities on the go, the accessibility and usability of your application process will directly influence your ability to attract top talent.
In today’s fast-paced digital landscape, where smartphones have become an extension of our lives, ensuring that your job application process is mobile friendly is no longer a choice – it’s a strategic imperative. As jobseekers increasingly rely on their mobile devices to search and apply for opportunities on the go, the accessibility and usability of your appli…

Amidst the current initiatives to develop more targeted anti-cancer therapies, immunotherapy has emerged as a highly potent option to selectively eliminate tumor cells with minimal side effects. Immunotherapies essentially make use of the body’s own immune system, or its components, to fight cancer. It is a relatively new concept, currently having achieved pharmacological success with targeted antibody-based therapeutics, including monoclonal and conjugated antibodies.
Amidst the current initiatives to develop more targeted anti-cancer therapies, immunotherapy has emerged as a highly potent option to selectively eliminate tumor cells with minimal side effects. Immunotherapies essentially make use of the body’s own immune system, or its components, to fight cancer. It is a relatively new con…

Dickkopf-1 (DKK1), is a protein that plays a critical role in regulating the Wnt signaling pathway, which is involved in various cellular processes, including cell proliferation, differentiation, and embryonic development. It is an important antagonist of the Wnt pathway, meaning that it inhibits Wnt signaling by binding to specific receptors and preventing the activation of downstream signaling molecules.
Introduction to DKK1 Dickkopf-1 (DKK1), is a protein that plays a critical role in regulating the Wnt signaling pathway, which is involved in various cellular processes, including cell proliferation, differentiation, and embryonic development. It is an important antagonist of the Wnt pathway, meaning that it inhibits Wnt signaling by binding to specific receptors and preventing the acti…

A tumor suppressor gene, also known as anti-onco gene, is an essential component of the body's defense against cancer. It usually facilitates apoptosis. With its absence, the human body will be functioning without its “brake” of cell proliferation. Cells are potent to go under abnormal growth processes and finally lead to tumor/cancer.
About Tumor Suppressor Genes A tumor suppressor gene, also known as anti-onco gene, is an essential component of the body's defense against cancer. It usually facilitates apoptosis. With its absence, the human body will be functioning without its “brake” of cell proliferation. Cells are potent to go under abnormal growth processes and finally lead to tumor/cancer. Here are some key features and functions of tumor suppressor genes: Inhibition of Cell Growth:…

In this article, we delve into 5 essential considerations to help you identify the ideal clients for your organisation, allowing you to successfully achieve your goal of connecting top talent with the organisations that are truly shaping the future of life sciences.
In the dynamic field of life science recruitment, your success as a recruitment agency depends on your ability to identify and collaborate with the right clients. Working with clients who are truly committed to investing in top talent whilst building strong partnerships with you will help you to maximise your chances of success, ultimately improving your industry reputation to both candidates and future clients. In this article, we delve into 5 essential considerations to help you identify the ideal clients for your organisation…

Structured data is the key building block for data exchange that delivers actionable insights. At Amplexor’s recent BE THE EXPERT 2023 global conference in June, Remco Munnik of Iperion - a Deloitte business, cautioned that there is no time to wait for the regulators. Pharma companies need to act now to see the benefits of data-driven process change.
The fact that Life Sciences is now adopting and seeing value in structured data is a huge turning point for the industry, and this acceptance is becoming increasingly palpable. Once companies are able to see beyond the mandatory detail of the regulations that are helping to drive data-oriented process change, their opportunities for transformation of entire functions and their approaches to product tracking and management will broaden and multi…

Homocysteine, an important biomarker in the field of clinical diagnostics, plays a significant role in assessing cardiovascular disease risk, vitamin deficiencies, and genetic disorders. Accurate and sensitive detection of homocysteine levels is crucial for early intervention and personalized patient care. In this article, we delve into the fascinating world of enzymes for producing the Homocysteine Assay Kit, shedding light on the mechanisms behind this powerful diagnostic tool.
Homocysteine, an important biomarker in the field of clinical diagnostics, plays a significant role in assessing cardiovascular disease risk, vitamin deficiencies, and genetic disorders. Accurate and sensitive detection of homocysteine levels is crucial for early intervention and personalized patient care. In this…

In the world of enzymes, one remarkable protein stands out for its exceptional properties and diverse applications – Kex2 Protease from Saccharomyces cerevisiae, Recombinant. This cutting-edge enzyme has garnered significant attention in the biotechnology industry due to its versatile nature and remarkable catalytic abilities. In this article, we will delve into the world of Kex2 Protease, exploring its origins, structure, and remarkable potential across various fields.
Introduction In the world of enzymes, one remarkable protein stands out for its exceptional properties and diverse applications – Kex2 Protease from Saccharomyces cerevisiae, Recombinant. This cutting-edge enzyme has garnered significant attention in the biotechnology industry due to its versatile nature and remarkable catal…

The gut microbiota, a diverse community of microorganisms residing in our gastrointestinal tract, plays a crucial role in maintaining our overall health. Probiotics, live microorganisms with potential health benefits, have garnered significant attention for their ability to promote gut health. In this article, we will delve into the science behind probiotic formulas, exploring their mechanisms of action and scientific evidence supporting their use in maintaining a healthy gut.
The gut microbiota, a diverse community of microorganisms residing in our gastrointestinal tract, plays a crucial role in maintaining our overall health. Probiotics, live microorganisms with potential health benefits, have garnered significant attention for their ability to promote gut health. In this article, we will…

Stable Isotope Labeling by Amino Acids in Cell Culture (SILAC) is a powerful technique that allows for the quantification and characterization of proteins in cells and organisms. It involves the substitution of specific amino acids with their isotopically labeled counterparts in cell culture media. This labeling enables researchers to track and compare protein expression levels, protein-protein interactions, and post-translational modifications, among other biological processes.
Several recent breakthroughs have been made using SILAC, enhancing its applications and expanding its potential. Here are some notable advancements: Proteome-wide analysis: SILAC has been used to perform comprehensive proteome-wide quantification, enabling the identification and quantification of thousands of protei…

Pichia pastoris is a type of yeast that is commonly used in biotechnology for the production of recombinant proteins. It is known for its ability to efficiently produce heterologous proteins with high yields. Pichia pastoris offers several advantages for protein production:
What is pichia pastoris and their functions? Pichia pastoris is a type of yeast that is commonly used in biotechnology for the production of recombinant proteins. It is known for its ability to efficiently produce heterologous proteins with high yields. Pichia pastoris offers several advantages for protein production: Strong and tightly regulated promoters: Pichia pastoris has strong promoters, such as the alcohol oxidase (AOX) promoter, which can drive high levels of protein expression. The AOX promo…

Microsphere technology is at the intersection of cutting-edge disciplines such as materials science, polymer technology, medical technology, and microelectronics.
Microspheres are small spherical entities formed by dispersing or adsorbing drugs in a polymer matrix. The particle size is typically between 1 μm and 250 μm, and the largest can reach more than 800 μm. Microsphere technology is at the intersection of cutting-edge disciplines such as materials science, polymer technology, medical technology, and microelectronics. Once injected into the body, microspheres are gradually degraded in the body, allowing the drug to be released slowly at a certain rate, maintaining the drug concentration in the blood at the site of the lesion, thereby prolonging the half-life of the drug and achieving l…