Articles
A genome-wide association study is what the National Institutes of Health call "a study of common genetic variation across the whole human genome with the goal of finding genetic links to observable traits."Even though family linkage studies and studies with tens of thousands of gene-based SNPs measure genetic variation across the genome, the National Institutes of Health definition requires a good density and selection of genetic markers to capture a large proportion of common variants in the study population, measured in enough people to give enough power to detect variants with modest effects.
Introduction to Genome-wide Association Studies A genome-wide association study is what the National Institutes of Health call "a study of common genetic variation across the whole human genome wit…
Introduction to Genome-wide Association Studies A genome-wide association study is what the National Institutes of Health call "a study of common genetic variation across the whole human genome wit…
Regulation of gene expression is fundamental to linking genotypes with phenotypes. RNAs shape complex gene expression networks, which drive biological processes. An in-depth understanding of the underlying mechanisms of how to govern these complex gene expression networks is vital for the treatment of complex diseases such as cancer. Hybridization-based microarrays are used to allow the simultaneous monitoring of expression levels of annotated genes in cell populations. However, genome-wide approaches have proven to provide more valuable insights into transcriptomes. These next- or third-generation sequencing platforms allow the rapid and cost-effective generation of massive amounts of sequence data. The RNA profiling by utilizing high-throughput sequencing technologies is known as RNA-seq.
04-Apr-2023
Small RNAs are important functional molecules in organisms, which have three main categories: microRNA (miRNA), small interfering RNA (siRNA), and piwi-interacting RNA (piRNA). They are less than 200 nt in length and are often not translated into proteins. Small RNA generally accomplishes RNA interference (RNAi) by forming the core of an RNA-protein complex (RNA-induced silencing complex, RISC). Small RNA sequencing, an example of targeted sequencing, is a powerful method for small RNA species profiling and functional genomic analysis. Here, we present the guidelines for bioinformatics analysis of small RNA sequencing.
Small RNAs are important functional molecules in organisms, which have three main categories: microRNA (miRNA), small interfering RNA (siRNA), and piwi-interacting RNA (piRNA…
Small RNAs are important functional molecules in organisms, which have three main categories: microRNA (miRNA), small interfering RNA (siRNA), and piwi-interacting RNA (piRNA…
Small RNAs are important functional molecules in organisms, which have three main categories: microRNA (miRNA), small interfering RNA (siRNA), and piwi-interacting RNA (piRNA). They are less than 200 nt in length and are often not translated into proteins. Small RNA generally accomplishes RNA interference (RNAi) by forming the core of an RNA-protein complex (RNA-induced silencing complex, RISC). Small RNA sequencing, an example of targeted sequencing, is a powerful method for small RNA species profiling and functional genomic analysis. Here, we present the guidelines for bioinformatics analysis of small RNA sequencing.
Small RNAs are important functional molecules in organisms, which have three main categories: microRNA (miRNA), small interfering RNA (siRNA), and piwi-interacting RNA (piRNA…
Small RNAs are important functional molecules in organisms, which have three main categories: microRNA (miRNA), small interfering RNA (siRNA), and piwi-interacting RNA (piRNA…
As the development of biological experimental technology, especially gene-sequencing technology, both laboratory and clinical researchers realize that genome sequencing is the best way to analyze the etiology, pathophysiology, treatment and prognosis of diseases. Researches further demonstrate that there are only 30 million base pairs of genes that contain essential information of proteins for human beings.
As the development of biological experimental technology, especially gene-sequencing technology, both laboratory and clinical researchers realize that genome sequencing is the best way to analyze the etiology, pathophysiology, treatment and prognosis of diseases. Researches further demonstrate that there are only 30 million base pairs of genes that contain essential information of protei…
As the development of biological experimental technology, especially gene-sequencing technology, both laboratory and clinical researchers realize that genome sequencing is the best way to analyze the etiology, pathophysiology, treatment and prognosis of diseases. Researches further demonstrate that there are only 30 million base pairs of genes that contain essential information of protei…
05-May-2023
Clinical Research Nurses (CRN) are specialised healthcare professionals who are integral to the development and implementation of clinical trials. Their responsibilities include participant recruitment, study coordination, data collection and analysis, study documentation, and ensuring regulatory compliance. CRNs play a crucial role in advancing medical research and developing new treatments and therapies by ensuring that clinical trials are conducted safely and effectively.
Clinical Research Nurses (CRN) are specialised healthcare professionals who are integral to the development and implementation of clinical trials. Their responsibilities include participant recruitment, study coordination, data collection and analysis, study documentation, and ensuring regulatory compliance. CRNs play a…
Clinical Research Nurses (CRN) are specialised healthcare professionals who are integral to the development and implementation of clinical trials. Their responsibilities include participant recruitment, study coordination, data collection and analysis, study documentation, and ensuring regulatory compliance. CRNs play a…
The principle of ion exchange resin is the process that ion exchange resin removes the salt in the solution.
How Do Ion Exchange Resins Work? Structure Ion exchange resins are composed of three parts: the insoluble three-dimensional space network polymer skeleton, the ion functional group connected to the skeleton, and the exchangeable ion pore with opposite charges on the functional group. Polymer skeleton: It is composed of cross-linked polymers, such as cross-linked polystyrene, polyacrylic acid, etc. Ion exchange group: It is connected to the polymer skeleton and has ionic functional groups with exchangeable ions, such as -SO3Na, -COOH, -N(CH3)3Cl, etc., or polar non-ionic functional groups, such as -N(CH3)2, -N(CH3)H, etc. Pore: It is the pore in the polymer structure (gel pore)…
How Do Ion Exchange Resins Work? Structure Ion exchange resins are composed of three parts: the insoluble three-dimensional space network polymer skeleton, the ion functional group connected to the skeleton, and the exchangeable ion pore with opposite charges on the functional group. Polymer skeleton: It is composed of cross-linked polymers, such as cross-linked polystyrene, polyacrylic acid, etc. Ion exchange group: It is connected to the polymer skeleton and has ionic functional groups with exchangeable ions, such as -SO3Na, -COOH, -N(CH3)3Cl, etc., or polar non-ionic functional groups, such as -N(CH3)2, -N(CH3)H, etc. Pore: It is the pore in the polymer structure (gel pore)…
A round-up of 20 of the top pharmaceutical recruitment agencies in the United Kingdom.
A round-up of 20 of the top pharmaceutical recruitment agencies in the United Kingdom. Achieva Group Ltd ACHIEVA has over three decades of experience in sourcing industry experts across a wide range of specialist sectors including Pharmaceuticals, Primary Care, Occupational Health, Health & Safety, Engineering, Development and Research. Actalent Actalent connections passion with purpose. Their scalable services and talent solutions drive value and results and provide the expertise to help their customers achieve more. Every day, their experts around the globe are making an impact. AL2S3 LTD Backed by well-known industry experts, AL Solutions is dedicated to making a real difference to the Life Science…
A round-up of 20 of the top pharmaceutical recruitment agencies in the United Kingdom. Achieva Group Ltd ACHIEVA has over three decades of experience in sourcing industry experts across a wide range of specialist sectors including Pharmaceuticals, Primary Care, Occupational Health, Health & Safety, Engineering, Development and Research. Actalent Actalent connections passion with purpose. Their scalable services and talent solutions drive value and results and provide the expertise to help their customers achieve more. Every day, their experts around the globe are making an impact. AL2S3 LTD Backed by well-known industry experts, AL Solutions is dedicated to making a real difference to the Life Science…
If you’re currently considering ditching the office and going for a remote role, you may be concerned about some of the potential drawbacks of working from home. In this article, we look at the top 10 concerns employees have around working remotely, from losing structure to having difficulty setting boundaries, providing tips on how to make sure remote working is right for you.
Remote and flexible working opportunities are on the rise within the Life Science industry. Although this way of working brings with it many benefits for employees, including more autonomy and a better work-life balance, not everyone thrives in a remote working environment. If you’re currently considering ditching the office and going for a remote role, you may be concerned about some of the potential drawbacks of wo…
Remote and flexible working opportunities are on the rise within the Life Science industry. Although this way of working brings with it many benefits for employees, including more autonomy and a better work-life balance, not everyone thrives in a remote working environment. If you’re currently considering ditching the office and going for a remote role, you may be concerned about some of the potential drawbacks of wo…
29-Mar-2023
With the introduction and popularization of Mini-LEDs with smaller LED light-emitting crystals, quantum dot technology will quickly become the standard choice for liquid crystal displays.
Since its commercial use in 2015, although liquid crystal displays equipped with quantum dot technology have significantly improved in display color gamut and rendering effects, their popularity is far below expectations. On the one hand, the maturity of quantum dot technology is not good, and the stability and cost of products are relatively high; on the other hand, the price of models using quantum dot display technology is relatively high, which hinders the popularization of technology. With the introduction and popularization of Mini-LEDs with smaller LED light-emitting crystals, quantum dot technology…
Since its commercial use in 2015, although liquid crystal displays equipped with quantum dot technology have significantly improved in display color gamut and rendering effects, their popularity is far below expectations. On the one hand, the maturity of quantum dot technology is not good, and the stability and cost of products are relatively high; on the other hand, the price of models using quantum dot display technology is relatively high, which hinders the popularization of technology. With the introduction and popularization of Mini-LEDs with smaller LED light-emitting crystals, quantum dot technology…
Oily raw materials, including oils, waxes, hydrocarbons, and higher fatty acids and higher alcohols are the main chemical ingredients used in cosmetics.
The composition of cosmetics is very complex and varies with different types. Most cosmetics are processed from the cosmetic matrix (base) plus some other necessary ingredients (additives). Cosmetic substrates are the basic raw materials of cosmetics. They are mainly oily raw materials, including oils, waxes, hydrocarbons, and higher fatty acids and higher alcohols that make up these ingredients. Salicylic acid Also known as β-hydroxy acid (BHA, beta hydroxy acid), salicylic acid has multiple functions and can solve various problems that cause acne. Dermatologists have used salicylic acid to exfoliate skin for decades, but it's also an…
The composition of cosmetics is very complex and varies with different types. Most cosmetics are processed from the cosmetic matrix (base) plus some other necessary ingredients (additives). Cosmetic substrates are the basic raw materials of cosmetics. They are mainly oily raw materials, including oils, waxes, hydrocarbons, and higher fatty acids and higher alcohols that make up these ingredients. Salicylic acid Also known as β-hydroxy acid (BHA, beta hydroxy acid), salicylic acid has multiple functions and can solve various problems that cause acne. Dermatologists have used salicylic acid to exfoliate skin for decades, but it's also an…
The global lab automation market is projected to reach USD 7.1 billion by 2028 from USD 5.1 billion in 2022, growing at a CAGR of 5.8%
Overview of Growth Trends, Applications, Benefits, and Future Outlook: The Lab Automation market is a rapidly growing industry that is focused on the automation of laboratory processes and systems. This market is driven by the need to reduce operational costs and increase efficiency, as well as the need to improve accuracy and consistency in laboratory results. Lab automation solutions include automated laboratory equipment, robotic systems, laboratory information management systems, laboratory software, and other related services. These solutions are used in a variety of industries, including pharmaceuticals, medical diagnostics, biotechnology, and research…
Overview of Growth Trends, Applications, Benefits, and Future Outlook: The Lab Automation market is a rapidly growing industry that is focused on the automation of laboratory processes and systems. This market is driven by the need to reduce operational costs and increase efficiency, as well as the need to improve accuracy and consistency in laboratory results. Lab automation solutions include automated laboratory equipment, robotic systems, laboratory information management systems, laboratory software, and other related services. These solutions are used in a variety of industries, including pharmaceuticals, medical diagnostics, biotechnology, and research…
The global companion diagnostics market is projected to reach USD 9.9 billion by 2026 from USD 5.5 billion in 2021, at a CAGR of 12.6%.
Introduction to Companion Diagnostics Market: Companion diagnostics are medical tests that are used to identify the patients who may benefit from a particular therapy, and to identify those patients who are more likely to respond to a given therapy. Companion diagnostics are used to select patients who are likely to benefit from a given treatment, and to identify those who are more likely to experience adverse effects from the same treatment. Companion diagnostics can also be used to monitor the effectiveness of a given treatment, and to identify potential drug-drug interactions. Companion diagnostics are rapidly becoming an essential part of personalized m…
Introduction to Companion Diagnostics Market: Companion diagnostics are medical tests that are used to identify the patients who may benefit from a particular therapy, and to identify those patients who are more likely to respond to a given therapy. Companion diagnostics are used to select patients who are likely to benefit from a given treatment, and to identify those who are more likely to experience adverse effects from the same treatment. Companion diagnostics can also be used to monitor the effectiveness of a given treatment, and to identify potential drug-drug interactions. Companion diagnostics are rapidly becoming an essential part of personalized m…
One word you don’t hear too often in current political discourse relating to Brexit is ‘streamlining’; but that’s exactly what the UK’s regulator hoped its Innovation Passport, which forms part of the Innovation Licensing and Access Pathway, would do for getting new drugs on the market more effectively when it was launched in early 2021.
One word you don’t hear too often in current political discourse relating to Brexit is ‘streamlining’; but that’s exactly what the UK’s regulator hoped its Innovation Passport, which forms part of the Innovation Licensing and Access Pathway, would do for getting new drugs on the market more effectively when it was launched in early 2021. It’s been two years since Belzutifan, a treatment developed by MSD UK Limited for von Hippel Lindau disease, was awarded…
One word you don’t hear too often in current political discourse relating to Brexit is ‘streamlining’; but that’s exactly what the UK’s regulator hoped its Innovation Passport, which forms part of the Innovation Licensing and Access Pathway, would do for getting new drugs on the market more effectively when it was launched in early 2021. It’s been two years since Belzutifan, a treatment developed by MSD UK Limited for von Hippel Lindau disease, was awarded…
14-Apr-2023
Recruiting top talent is crucial for the success of any Life Science organisation, but finding the right candidates can often be a challenging and time-consuming process. In today’s digital age, it’s important to leverage multiple channels and techniques to reach a wider pool of candidates and ensure your job postings are visible to the right people.
Recruiting top talent is crucial for the success of any Life Science organisation, but finding the right candidates can often be a challenging and time-consuming process. In today’s digital age, it’s important to leverage multiple channels and techniques to reach a wider pool of candidates and ensure your job postings are visible to the right people. In this article, we explore 7 effective strategies to help you get your jobs in front of more p…
Recruiting top talent is crucial for the success of any Life Science organisation, but finding the right candidates can often be a challenging and time-consuming process. In today’s digital age, it’s important to leverage multiple channels and techniques to reach a wider pool of candidates and ensure your job postings are visible to the right people. In this article, we explore 7 effective strategies to help you get your jobs in front of more p…
Flanders, the northern region of Belgium, has a long history of collaboration in life sciences, particularly with the UK. Most recently in the development of the Covid vaccine. It was in Flanders that more than 90% of all UK vaccines were made. It is currently unclear what the recent Windsor Agreement will mean for our collaboration on life sciences and whether the UK will re-join Horizon Europe Research Program but it is useful to review the impact of collaboration in life sciences.
Flanders, the northern region of Belgium, has a long history of collaboration in life sciences, particularly with the UK. Most recently in the development of the Covid vaccine. It was in Flanders that more than 90% of all UK vaccines were made. It is currently unclear what the recent Windsor Agreement will mean…
Flanders, the northern region of Belgium, has a long history of collaboration in life sciences, particularly with the UK. Most recently in the development of the Covid vaccine. It was in Flanders that more than 90% of all UK vaccines were made. It is currently unclear what the recent Windsor Agreement will mean…
Coordination compounds have long been concerned and researched for their applications in catalysis, supramolecular chemistry, magnetism, electrochemistry, nanoscience, energy materials, and biological applications.
Coordination chemistry investigates the characteristics of coordination compounds formed by the interaction between metal atoms or ions and inorganic, organic ions or molecules, as well as their bonding, structure, reaction, classification, and preparation. These compounds possess a wealth of structural, physicochemical, and catalytic properties. Meanwhile, coordination compounds have long been concerned and researched for their applications in catalysis, supramolecular chemistry, magnetism, electrochemistry, nanoscience, energy materials, and biological applications. Here,…
Coordination chemistry investigates the characteristics of coordination compounds formed by the interaction between metal atoms or ions and inorganic, organic ions or molecules, as well as their bonding, structure, reaction, classification, and preparation. These compounds possess a wealth of structural, physicochemical, and catalytic properties. Meanwhile, coordination compounds have long been concerned and researched for their applications in catalysis, supramolecular chemistry, magnetism, electrochemistry, nanoscience, energy materials, and biological applications. Here,…
In the latest installment of our Diversity, Equity & Inclusion Leadership series, we spoke to Charlotte Valeur, an experienced Non-Executive Director and listed company Chair. Charlotte brings over 35 years of executive and governance experience, and as an advocate of Neurodiversity, she founded Institute Of Neurodiversity, ION. Charlotte talks about her late diagnosis of autism, the importance of talking about Neurodiversity, and what she hopes the ION can achieve for others.
“…The more influential people speak openly about their neurodivergence and use their influence to lift all neurodivergent people, the more we can drive the correct narrative to support and protect the most vulnerable in our community…” In the latest installment of our Diversity, Equity & Inclusion Leadership serie…
“…The more influential people speak openly about their neurodivergence and use their influence to lift all neurodivergent people, the more we can drive the correct narrative to support and protect the most vulnerable in our community…” In the latest installment of our Diversity, Equity & Inclusion Leadership serie…
Discover the top 5 clinical trial technology trends in 2023. From wearables to AI, Digital Patient engagement tools and techniques that are shaping the future of clinical research
Clinical trials play a crucial role in the development and approval of new medical treatments and drugs. As technology continues to advance, Clinical Trial Technology is becoming a more important factor in shaping the way trials are conducted. In 2023, we can expect to see several technology trends that are set to further revolutionize the design, conduct, and analysis of trials. Some of these trends include decentralized trials, wearable devices, machine learning, and Risk-Based Quality Management (RBQM). Growing Use of Machine Learning and AI AI and Machine learning are becoming increasingly important in clin…
Clinical trials play a crucial role in the development and approval of new medical treatments and drugs. As technology continues to advance, Clinical Trial Technology is becoming a more important factor in shaping the way trials are conducted. In 2023, we can expect to see several technology trends that are set to further revolutionize the design, conduct, and analysis of trials. Some of these trends include decentralized trials, wearable devices, machine learning, and Risk-Based Quality Management (RBQM). Growing Use of Machine Learning and AI AI and Machine learning are becoming increasingly important in clin…
In today’s competitive Life Science job market, continuously improving your skills and knowledge is essential when looking to increase your earning potential. Whether you are just starting out or looking to advance your career, there are numerous ways of developing your expertise and growing your skillset, from taking courses and attending industry events to joining professional organisations and finding a mentor.
In today’s competitive Life Science job market, continuously improving your skills and knowledge is essential when looking to increase your earning potential. Whether you are just starting out or looking to advance your career, there are numerous ways of developing your expertise and growing your skillset, from taking courses and attending industry events to joining professional o…
In today’s competitive Life Science job market, continuously improving your skills and knowledge is essential when looking to increase your earning potential. Whether you are just starting out or looking to advance your career, there are numerous ways of developing your expertise and growing your skillset, from taking courses and attending industry events to joining professional o…
