Articles
Solentim, the global leader for solutions to create, isolate and characterize the highest value cells for the development of new biological medicines, yesterday launched a dedicated new workflow for single cell cloning of human induced pluripotent stem cells (hiPSCs). A combination of Solentim’s VIPS™ (verified in-situ plate seeding) instrument and the new MatriClone™ matrix has been shown to give a 4 to 5-fold improvement in cloning efficiency compared with traditional limiting dilution methods.
VIPS™ + MatriClone™ combination ensures high efficiency seeding of hiPSCs with high viability Bournemouth, UK, 23rd September 2020 / Sciad Newswire / Solentim, the global leader for solutions to create, isolate and characterize the highest value cells f…
VIPS™ + MatriClone™ combination ensures high efficiency seeding of hiPSCs with high viability Bournemouth, UK, 23rd September 2020 / Sciad Newswire / Solentim, the global leader for solutions to create, isolate and characterize the highest value cells f…
With World Sepsis Day on 13th September 2020, Dr Ron Daniels BEM, Chief Executive of the UK Sepsis Trust, provides his thoughts on the importance of standardising the national track and trigger systems across primary and secondary care to improve early detection in the deterioration of patients.
Standardising the process of monitoring patients to quickly and effectively detect deterioration, is a problem faced by healthcare professionals across the UK. With staffing issues, inter-observer discrepancies and transcription error there are many variables that impact on patient assessments which can subsequently lead to poor outcomes. Studies show that Respiratory Rate (RR) changes 6-8 hours before a major event, and by using a standardised track and trigger process such as NEWS2 to identify a…
Standardising the process of monitoring patients to quickly and effectively detect deterioration, is a problem faced by healthcare professionals across the UK. With staffing issues, inter-observer discrepancies and transcription error there are many variables that impact on patient assessments which can subsequently lead to poor outcomes. Studies show that Respiratory Rate (RR) changes 6-8 hours before a major event, and by using a standardised track and trigger process such as NEWS2 to identify a…
The UK has a thriving life sciences sector. With three of the world’s top ten universities in the field – Oxford, Cambridge and UCL – plus prominent bioscience clusters in other British university cities such as Nottingham and Cardiff, UK research accounts for 12% of all life sciences academic citations worldwide (and nearly a fifth of the top 1% of these).
The UK has a thriving life sciences sector. With three of the world’s top ten universities in the field – Oxford, Cambridge and UCL – plus prominent bioscience clusters in other British university cities such as Nottingham and Cardiff, UK research accounts for 12% of all life sciences academic citations worldwide (and nearly a fifth of the top 1% of these). At the same time, the UK performs well at converting academic prowess into start…
The UK has a thriving life sciences sector. With three of the world’s top ten universities in the field – Oxford, Cambridge and UCL – plus prominent bioscience clusters in other British university cities such as Nottingham and Cardiff, UK research accounts for 12% of all life sciences academic citations worldwide (and nearly a fifth of the top 1% of these). At the same time, the UK performs well at converting academic prowess into start…
In the past, the primary role of the Affiliate office was to liaise with local health authorities. However with the harmonisation and globalisation of pharmacovigilance regulations, its role has been extended more recently to perform multiple roles.
In the past, the primary role of the Affiliate office was to liaise with local health authorities. However with the harmonisation and globalisation of pharmacovigilance regulations, its role has been extended more recently to perform multiple roles. In addition to liaising with the local health authorities, Affiliate offices are now performing more commercially focused activities and as a consequence the risk of pharmacovigilance activities being overlooked has increased. This can have repercussions for the pharmacovigilance manager who i…
In the past, the primary role of the Affiliate office was to liaise with local health authorities. However with the harmonisation and globalisation of pharmacovigilance regulations, its role has been extended more recently to perform multiple roles. In addition to liaising with the local health authorities, Affiliate offices are now performing more commercially focused activities and as a consequence the risk of pharmacovigilance activities being overlooked has increased. This can have repercussions for the pharmacovigilance manager who i…
04-Sep-2020
Pete Smallwood, Business Development Manager at speciality security printer Eltronis, highlights how the latest labels and technologies are protecting genuine items from counterfeit and providing quick, simple and effective authentication to both brand owners and consumers.
In April this year, Europol highlighted significant growth in counterfeit products being sold during the COVID-19 crisis, with the pandemic providing ‘the ideal opportunity for criminals seeking to produce and distribute counterfeit and substandard goods’[1]. According to the report, pharmaceutical and medical items have been the key targets, but so have foods, with the substitution of meat and milk as well as the manufacture of fake supplements and vitamins. Not only do these goods not meet the required quality standar…
In April this year, Europol highlighted significant growth in counterfeit products being sold during the COVID-19 crisis, with the pandemic providing ‘the ideal opportunity for criminals seeking to produce and distribute counterfeit and substandard goods’[1]. According to the report, pharmaceutical and medical items have been the key targets, but so have foods, with the substitution of meat and milk as well as the manufacture of fake supplements and vitamins. Not only do these goods not meet the required quality standar…
Virtual pharma companies characterised by small, agile and innovation-led operations have traditionally partnered with - or even been absorbed by - much bigger players in order to get their product to market.
Virtual pharma companies characterised by small, agile and innovation-led operations have traditionally partnered with - or even been absorbed by - much bigger players in order to get their product to market. Relying on the resources and expertise of these partners has been an essential part of their journey beyond the pure science - from getting through regulatory processes, clinical trials and manufacturing right through to marketing, supply chain design, sales, distribution and all the other post-launch activities. Increasingly, however, virtual pharma operations are seeking to tak…
Virtual pharma companies characterised by small, agile and innovation-led operations have traditionally partnered with - or even been absorbed by - much bigger players in order to get their product to market. Relying on the resources and expertise of these partners has been an essential part of their journey beyond the pure science - from getting through regulatory processes, clinical trials and manufacturing right through to marketing, supply chain design, sales, distribution and all the other post-launch activities. Increasingly, however, virtual pharma operations are seeking to tak…
19-Mar-2021
While negotiations are still ongoing, the structure of the post-Brexit medicine testing and approval process is still unclear, and the UK government has so far ruled out an extension to the transition period which is due to come to an end at the end of this year.
While negotiations are still ongoing, the structure of the post-Brexit medicine testing and approval process is still unclear, and the UK government has so far ruled out an extension to the transition period which is due to come to an end at the end of this year. What is clear is that the Medicines and Healthcare products Regulatory Agency (MHRA) is becoming independent to the EMA’s drug approval and oversight process. It might result in the testing and release of products being completed under two separate regulatory frameworks. D…
While negotiations are still ongoing, the structure of the post-Brexit medicine testing and approval process is still unclear, and the UK government has so far ruled out an extension to the transition period which is due to come to an end at the end of this year. What is clear is that the Medicines and Healthcare products Regulatory Agency (MHRA) is becoming independent to the EMA’s drug approval and oversight process. It might result in the testing and release of products being completed under two separate regulatory frameworks. D…
19-Mar-2021
With the NHS being under considerable pressure not least with the current health crisis, Penny Pinnock, Sales Manager – Healthcare & Public Sector for Siemens Financial Services (SFS) explains why hospitals must look towards more flexible and sustainable ways of financing their investments in new diagnostic equipment.
Even before the healthcare crisis and its economic impact, growing, ageing populations have been applying pressure to healthcare systems worldwide. In response, preventative medicine has become a vitally important area of development, which intends to help offset the growing burden of increasingly prevalent non-communicable diseases (NCDs) also known as chronic illnesses. By identifying potential health risks early on, action can swiftly be taken to prevent further aggravatio…
Even before the healthcare crisis and its economic impact, growing, ageing populations have been applying pressure to healthcare systems worldwide. In response, preventative medicine has become a vitally important area of development, which intends to help offset the growing burden of increasingly prevalent non-communicable diseases (NCDs) also known as chronic illnesses. By identifying potential health risks early on, action can swiftly be taken to prevent further aggravatio…
25-Aug-2020
Healthcare systems globally are increasingly recognising the value of healthcare data. From developing improved care pathways to driving cost savings through data analytics, arguably the true value of healthcare data lies in patient outcomes.
Healthcare systems globally are increasingly recognising the value of healthcare data. From developing improved care pathways to driving cost savings through data analytics, arguably the true value of healthcare data lies in patient outcomes. Good data can power better, safer and more effective models of care for patients. As technology unlocks new data sets and more sophisticated tools of analysis, our ability to harness information will be key to driving better health outcomes and more sustainable models of care. Yet while the value of ‘longitudinal…
Healthcare systems globally are increasingly recognising the value of healthcare data. From developing improved care pathways to driving cost savings through data analytics, arguably the true value of healthcare data lies in patient outcomes. Good data can power better, safer and more effective models of care for patients. As technology unlocks new data sets and more sophisticated tools of analysis, our ability to harness information will be key to driving better health outcomes and more sustainable models of care. Yet while the value of ‘longitudinal…
Life sciences organisations are gradually realising that if they could stop managing regulated product information as a series of monolithic documents created from scratch each time, they could transform everything from regulatory information and submissions management, to global/local labelling and quality & safety validation. But how do they get to that point? Romuald Braun of Amplexor advises on a gradual transformation.
Life sciences organisations are gradually realising that if they could stop managing regulated product information as a series of monolithic documents created from scratch each time, they could transform everything from regulatory information and submissions management, to global/local labelling and quality & safety validation. But how do they get to that point? Romu…
Life sciences organisations are gradually realising that if they could stop managing regulated product information as a series of monolithic documents created from scratch each time, they could transform everything from regulatory information and submissions management, to global/local labelling and quality & safety validation. But how do they get to that point? Romu…
There is a lot of research taking place in the pharmaceutical industry today. What are some of the biggest trends that everyone should note?
The worldwide pharmaceutical market has grown by leaps and bounds during the past few years. Given the massive impact that the COVID-19 pandemic has had on the world, the pharmaceutical industry is still looking for ways to provide helpful products to those who need them most. The good part about this industry is that they are quick to pump new funds back into their own research in an effort to continue to help others. With this in mind, there are a few major trends that are dominating the landscape of the pharmaceutical industry and they will play a role in the development of this field in the years to come. The Growth of AI Tech for Resea…
The worldwide pharmaceutical market has grown by leaps and bounds during the past few years. Given the massive impact that the COVID-19 pandemic has had on the world, the pharmaceutical industry is still looking for ways to provide helpful products to those who need them most. The good part about this industry is that they are quick to pump new funds back into their own research in an effort to continue to help others. With this in mind, there are a few major trends that are dominating the landscape of the pharmaceutical industry and they will play a role in the development of this field in the years to come. The Growth of AI Tech for Resea…
Cancer research has come a long way during the past several years. What does the future of cancer treatment look like?
The past few years have been an exciting time in the field of cancer research as some of the top minds in the world try to find ways to fight a disease that is only becoming more common. There are a few top cancer research findings that have risen to the surface. 1. Cancer Energy Source First, researchers found that cancer cells need an unlimited supply of energy and this usually comes in the form of glucose. A research team found that leukemia cells, a type of blood cancer, will undercut the ability of normal cells to consume glucose. They were able to steal glucose from healthy cells, fueling the growth and spread of cancer throughout the body. Furthermore, the r…
The past few years have been an exciting time in the field of cancer research as some of the top minds in the world try to find ways to fight a disease that is only becoming more common. There are a few top cancer research findings that have risen to the surface. 1. Cancer Energy Source First, researchers found that cancer cells need an unlimited supply of energy and this usually comes in the form of glucose. A research team found that leukemia cells, a type of blood cancer, will undercut the ability of normal cells to consume glucose. They were able to steal glucose from healthy cells, fueling the growth and spread of cancer throughout the body. Furthermore, the r…
GenBrain is the dietary supplement which is known to just improve the overall mental health of the person. This supplement is right made up of the special natural ingredients, the Vitamin B6, also the Amino Acids to simply work ready for the overall nervous system.
Right in today’s world, the really unhealthy lifestyle simply has become the really norm of the living. Also these all things leads right to the number of the many kind of health problems, simply including the physical also the mental. The stress, the depression, the mental fatigue, also the memory loss are just some of mental issues which we have to simply deal right with as all of us grow old. All of these are just said to be the really inevitable issues with the old age, but all of us need to just agree that the…
Right in today’s world, the really unhealthy lifestyle simply has become the really norm of the living. Also these all things leads right to the number of the many kind of health problems, simply including the physical also the mental. The stress, the depression, the mental fatigue, also the memory loss are just some of mental issues which we have to simply deal right with as all of us grow old. All of these are just said to be the really inevitable issues with the old age, but all of us need to just agree that the…
Is there a chance that COVID-19 could lead to bankruptcies for life science companies due to supply chain issues? There are a few key points.
The COVID-19 pandemic has impacted everyone and as healthcare organizations and life sciences companies scramble to try to make a vaccine against this deadly virus, there is a growing concern that the COVID-19 pandemic is going to place an undue amount of stress on companies in this sector. Similar to other industries, these businesses have had to adapt their products and services to not only aid in the response to the COVID-19 pandemic but also to meet the growing demand for their services. As they try to maintain shareholder value and navigate numerous regulatory hurdles that are related to the COVID-19 pandemic, there is a growing concern that th…
The COVID-19 pandemic has impacted everyone and as healthcare organizations and life sciences companies scramble to try to make a vaccine against this deadly virus, there is a growing concern that the COVID-19 pandemic is going to place an undue amount of stress on companies in this sector. Similar to other industries, these businesses have had to adapt their products and services to not only aid in the response to the COVID-19 pandemic but also to meet the growing demand for their services. As they try to maintain shareholder value and navigate numerous regulatory hurdles that are related to the COVID-19 pandemic, there is a growing concern that th…
24-Aug-2020
When Swine Flu came, skeptics saw a catastrophe that would bring the world's economy to its knees. Forward-thinkers saw an opportunity to be part of the solution and cashed on it. The current pandemic is not any different; the pharmacy industry can reap the Covid-19 windfall
We are in the middle of a once-in-a-century crisis that has spread across the world in a matter of months. The pharmacy industry has moved quickly into a crisis mindset, managing people's implications, protecting the business, and trying to be part of the solution. Two critical uncertainties will frame how the industry will emerge post-COVID. The first one is the depth and the duration of Covid-19 disruptions. The other fact is how bold the stakeholders are, and their willpower and ability to align with the new world or…
We are in the middle of a once-in-a-century crisis that has spread across the world in a matter of months. The pharmacy industry has moved quickly into a crisis mindset, managing people's implications, protecting the business, and trying to be part of the solution. Two critical uncertainties will frame how the industry will emerge post-COVID. The first one is the depth and the duration of Covid-19 disruptions. The other fact is how bold the stakeholders are, and their willpower and ability to align with the new world or…
Within this article, the use of coagulation testing is discussed in assessing the potential outcomes for COVID positive cases.
With the level of incidence of thrombosis in patients admitted to hospital in severe condition due to the disease, coagulation tests such as D-dimer, prothrombin time (PT) and activated partial thromboplastin time (aPTT) have become important indicators for hospitals. A study published by a French group in May 2020 in Intensive Care Medicine (1) shows an increase in the occurrence of prothrombotic events, especially pulmonary thromboembolisms, in patients with severe clinical symptoms of Covid-19 infection. Given the urgency of the current situation caused by the new coronavirus (Sars-CoV-2) pandemic, studies on this topic have been intensified worldwide at a rec…
With the level of incidence of thrombosis in patients admitted to hospital in severe condition due to the disease, coagulation tests such as D-dimer, prothrombin time (PT) and activated partial thromboplastin time (aPTT) have become important indicators for hospitals. A study published by a French group in May 2020 in Intensive Care Medicine (1) shows an increase in the occurrence of prothrombotic events, especially pulmonary thromboembolisms, in patients with severe clinical symptoms of Covid-19 infection. Given the urgency of the current situation caused by the new coronavirus (Sars-CoV-2) pandemic, studies on this topic have been intensified worldwide at a rec…
Data-sharing is crucial for any supply chain activity. But for drug manufacturing and the pharmaceutical sector, it has to be top-notch because the process is multi-layered and complicated. Considering the DSCSA guidance with the aim to combat circulation of counterfeit medicines, information-sharing in this particular sector should not just be streamlined but also be fast and secured. While error-free serialization is a pre-requisite for pharmaceutical track and trace under DSCSA compliance norms, the information in the form of data encryption is a mandate to increase the efficiency and security of the pharmaceutical supply chain.
Pharmaceutical Track and Trace: Sharing the Right Data for a Competent Supply Chain Management Data-sharing is crucial for any supply chain activity. But for dr…
Pharmaceutical Track and Trace: Sharing the Right Data for a Competent Supply Chain Management Data-sharing is crucial for any supply chain activity. But for dr…
The Covid-19 crisis is having an immense impact on every sector, damaging organisations of all sizes. That being said, while the pandemic is undoubtably far from over, there is finally a light at the end of tunnel, with positive signs of recovery appearing across the globe.
The Covid-19 crisis is having an immense impact on every sector, damaging organisations of all sizes. That being said, while the pandemic is undoubtably far from over, there is finally a light at the end of tunnel, with positive signs of recovery appearing across the globe. Deaths and infection rates across Europe are significantly decreasing, global restrictions are continuing to ease and a UK team has recently discovered that dexamethasone is a viable treatment for the sickest patients. Meanwhile, scientists across the…
The Covid-19 crisis is having an immense impact on every sector, damaging organisations of all sizes. That being said, while the pandemic is undoubtably far from over, there is finally a light at the end of tunnel, with positive signs of recovery appearing across the globe. Deaths and infection rates across Europe are significantly decreasing, global restrictions are continuing to ease and a UK team has recently discovered that dexamethasone is a viable treatment for the sickest patients. Meanwhile, scientists across the…
What are the supply chain challenges for delivering a vaccine? Delivering a new vaccine for COVID-19 worldwide will be one of the greatest challenges faced by modern pharma. The difficulties are intensified by pre-existing shortcomings in the supply chain.
COVID-19 has impacted every country around the world since its arrival in late 2019, either directly or indirectly due to its effect on the global economy. However, things are looking up. By the end of 2021, the WHO plans to deliver over 2 billion doses of a Coronavirus vaccine. The scientific research community is making strong ground. As of 22nd July, there are 24 candidate vaccines in clinical evaluation, some of which have already entered the final phase of clinical trials. But this is an ambitious timeline and presents huge challen…
COVID-19 has impacted every country around the world since its arrival in late 2019, either directly or indirectly due to its effect on the global economy. However, things are looking up. By the end of 2021, the WHO plans to deliver over 2 billion doses of a Coronavirus vaccine. The scientific research community is making strong ground. As of 22nd July, there are 24 candidate vaccines in clinical evaluation, some of which have already entered the final phase of clinical trials. But this is an ambitious timeline and presents huge challen…
Two-year long project cycles are no longer an option as the pace of change accelerates to meet the demands of fast-changing market conditions. Life sciences companies know that technology can help them drive greater responsiveness from IT teams and suppliers to the changing needs of the business.
Two-year long project cycles are no longer an option as the pace of change accelerates to meet the demands of fast-changing market conditions. Life sciences companies know that technology can help them drive greater responsiveness from IT teams and suppliers to the changing needs of the business. But agile development needs to extend beyond the IT department, if companies are to see the benefits of faster business transformation, argues Romuald Braun, VP of Strategy for Life Sciences at Amplexor. …
Two-year long project cycles are no longer an option as the pace of change accelerates to meet the demands of fast-changing market conditions. Life sciences companies know that technology can help them drive greater responsiveness from IT teams and suppliers to the changing needs of the business. But agile development needs to extend beyond the IT department, if companies are to see the benefits of faster business transformation, argues Romuald Braun, VP of Strategy for Life Sciences at Amplexor. …
