Articles

Serum enzyme tests have been used in clinical practice for a long time, such as increased amylase activity in serum and urine of patients with acute pancreatitis. In the 1930s, some scholars reported that the determination of serum lipase and alkaline phosphatase activities is helpful for the diagnosis of pancreatitis and bone diseases, respectively.
Serum enzyme tests have been used in clinical practice for a long time, such as increased amylase activity in serum and urine of patients with acute pancreatitis. In the 1930s, some scholars reported that the determination of serum lipase and alkaline phosphatase activities is helpful for the diagnosis of pancreatitis and bone diseases, respectively.   After the 1950s, the application of serum enzyme activity measurement as an indicator fo…

In this article Jon Geater, chief technology officer at RKVST, introduces a new acronym, SCITT, provides some explanation and discusses why it is important for the pharmaceutical industry.
What is SCITT?  While it may be yet another term you might not have heard of, it’s sure to become more familiar to pharmaceutical industry players as we strive to ensure traceability, accountability, and auditability across the supply chain.  The term SCITT stands for ‘Supply Chain Integrity, Transparency, and Trust’. While there’s ongoing discussion over its scope and definition, at its core, it’s pretty simple: risk vests in the operator of equipment but originates at every point in the supply chain. If pharmaceutical companies and other players in the pharma supply chain are to take control of, and res…

If you are looking to break into the field of pharmaceuticals or life sciences, there are a few things to consider that can help make the transition a success. Pharmaceuticals and life sciences involve complex scientific work environments, so having an understanding and knowledge of the industry is important. Let’s explore the things you need to consider before exploring a career change into the life sciences.
If you are looking to break into the field of pharmaceuticals or life sciences, there are a few things to consider that can help make the transition a success. Pharmaceuticals and life sciences involve complex scientific work environments, so having an understanding and knowledge of the industry is important.  Let’s explore the things you need to consider before exploring a career cha…

Also known as Clinical Trial Managers or Clinical Study Managers, Clinical Project Managers (CPM) are responsible for planning and coordinating clinical research projects. They direct the activities of workers engaged in clinical research projects to ensure compliance with protocols and overall clinical objectives.
Also known as Clinical Trial Managers or Clinical Study Managers, Clinical Project Managers (CPM) are responsible for planning and coordinating clinical research projects. They direct the activities of workers engaged in clinical research projects to ensure compliance with protocols and overall clinical objectives. What are the Main Responsibilities of a CPM? The responsibilities of a CPM may vary, but often include: Maintaining required records of study activity, including case…

In-house legal teams are an indispensable resource to a business, especially in heavily IP-driven sectors such as life sciences and pharmaceuticals. The current economic choppy waters mean having talented legal brains in the boardroom to tackle a range of business-critical decisions is more important than ever. However, against this challenging backdrop, how can pharma companies compete with the pay wars being waged by law firms to lure talented lawyers in-house?
In-house legal teams are an indispensable resource to a business, especially in heavily IP-driven sectors such as life sciences and pharmaceuticals. The current economic choppy waters mean having talented legal brains in the boardroom to tackle a range of business-critical decisions is more important than ever. However, against thi…

One cause of burnout amongst employees is hidden overwork, a trend that is becoming more prevalent with the current economic climate which is putting many workers under increasing amounts of pressure to perform well at work. In this article, we look at what hidden overwork really looks like, how it may be impacting life science employees, and what employers can do to help.
Burnout amongst workers is on the rise, with 38% of people in a 2022 study experiencing burnout at work, reporting feelings of exhaustion, reduced efficacy, and cynicism. Burnout has become particularly challenging for remote workers, with the same study finding that those working from home more than 80% of the time are the group most likely to experience this, with this group also receiving the lowest level of organisati…

Whole genome sequencing (WGS) has the capacity to greatly enhance genomic knowledge and understand mysteries of life by utilizing the most advanced genetic sequencing technologies. WGS can be used for variant calling, genome annotation, phylogenetic analysis, reference genome construction, and more. WGS tries to cover the whole genome, but actually covers 95% of the genome with technical difficulties in sequencing regions such as centromeres and telomeres. Another challenge for WGS is data management. As larger datasets become more accessible and affordable, computational analysis will be the rate-limiting factor rather than sequencing technology. Here we will discuss the bioinformatics workflow for detection of genetic variations in WGS to help you get through it.
Whole genome sequencing (…

Working in the life science industry can be extremely rewarding, with a unique opportunity to save lives and improve the quality of life for patients across the globe. Whether you see yourself working in a laboratory researching molecules for use in drug development, or in an office processing contracts and other legal documents to kickstart a clinical trial, the work you do in the industry has a real, meaningful impact on people’s lives worldwide.
Working in the life science industry can be extremely rewarding, with a unique opportunity to save lives and improve the quality of life for patients across the globe. Whether you see yourself working in a laboratory researching molecules for use in drug development, or in an office processing contracts and other legal documents to kickstart a cl…

In order to attract top talent in the life science industry, you need to ensure you’re providing the best possible experience for your candidates, from the minute you post a job advert to the moment they’re offered the job, and even beyond. 7 in 10 jobseekers who receive a poor candidate experience will never want to work for that organisation again, with 72% also saying that they’d be likely to tell friends, colleagues, and family members about the experience.
In order to attract top talent in the life science industry, you need to ensure you’re providing the best possible experience for your candidates, from the minute you post a job advert to the moment they’re offered the job, and even beyond. 7 in 10 jobseekers who receive a poor candidate experience will never want to work for that or…

When searching for your next life science job, it’s important to remember that there’s more to a job than a salary. When deciding whether or not to accept a job offer, you need to consider the entire job package, including things like company culture and career progression as well as the salary and benefits on offer.
When searching for your next life science job, it’s important to remember that there’s more to a job than a salary. When deciding whether or not to accept a job offer, you need to consider the entire job package, including things like company culture and career progression as well as the salary and benefits on offer. In this article, we’ve highlighted 9 reasons you might want to turn down a job offer, with advice on steps you can take before turning it down. The Salary Isn’t Hi…

Chronic Obstructive Pulmonary Disease, or COPD, has been branded as the "silent killer." It is because some people do not even know they have it until it becomes too dangerous to handle. Millions of people in the United States have COPD but have not been diagnosed because they are unaware of it. This implies that they also do not get treatment for it. This is when the disease becomes a threat to life. Let us first learn more about COPD.
Chronic Obstructive Pulmonary Disease, or COPD, has been branded as the "silent killer." It is because some people do not even know they have it until it becomes too dangerous to handle. Millions of people in the United States have COPD but have not been diagnosed because they are unaware of it. This implies that they also do not get treatment for it. This i…

Carbon nanomaterials have been speedily developed due to their unique electronic, optical, thermal, mechanical, and chemical nature.
History of Development As early as 1985, the discovery of fullerene with the “football” structure immediately attracted the world’s attention. Then, carbon nanotubes with a hollow cylindrical structure are formed based on mild modifications toward fullerenes. In 1991, Japanese researchers discovered carbon nanotubes in carbon fibers for the first time. In 2004, researchers discovered the 2D planar nanomaterial whose planar thickness is confined to the nanoscale range. At the same time, researchers also developed a practical “scotch tape” technique to separate single-layer graphene from bulk graphene. Buckyballs (fullerenes), carbon nanotubes, and graphene all…

To attract the best talent in the life science industry, you need to ensure that you’re not only providing people with a job that will pay the bills, but also a unique company culture and a superior employee experience. In other words, you need to position your organisation as an employer of choice.
To attract the best talent in the life science industry, you need to ensure that you’re not only providing people with a job that will pay the bills, but also a unique company culture and a superior employee experience. In other words, you need to position your organisation as an employer of choice. To attract top talent, you need to present your organisation as a top employer, showing jobseekers exactly what they will gain through working for you beyond a salary. This article looks at 9 things…

Clinical Research Associates (CRA) are responsible for organising and monitoring clinical trials, helping to identify the benefits and risks of new and pre-existing drugs, ensuring they’re effective and safe for their intended use. CRAs are often involved in all stages of a clinical trial, from identifying a relevant investigational site and setting up the trial, to closing down the trial and preparing final reports.
Clinical Research Associates (CRA) are responsible for organising and monitoring clinical trials, helping to identify the benefits and risks of new and pre-existing drugs, ensuring they’re effective and safe for their intended use. CRAs are often involved in all stages of a clinical trial, from identifying a relevant investigational site and setting up the trial, to closing dow…

Bachem is a leading, innovation-driven company specialising in the development and manufacture of peptides and oligonucleotides. With 50 years of experience, Bachem provides products for research, clinical development and commercial application to pharmaceutical and biotechnology companies worldwide and offers a comprehensive range of services. Bachem operates internationally, with headquarters in Switzerland and locations in Europe, the US and Asia. The company is listed on the SIX Swiss Exchange.
Oligonucleotides are short, single or double-stranded fragments of DNA or RNA that can be used for therapeutic purposes. Originally, there was an emphasis on using this new drug modality for treating rare diseases, yet they have also shown great potential to be used for more common diseases. …

ICH Q3D presents major challenges to testing and risk assessments associated with meeting current rigorous limits for specific components to assess patient risk. The probability that sure elemental impurities area unit gift in a very healthful product ought to be determined through a legitimate risk assessment.
The mission of the International Council for Harmonisation of Technical needs for prescription drugs for Human Use (ICH) is to make sure safe, effective, and high-quality medicines area units are developed and distributed. This is often accomplished by making worldwide harmonization. Harmonization achievements within the quality space include: Essential milestones like the conduct of stability studies Process relevant thresholds for impurities testing A lot of versatile approaches t…

The biotech industry is a large and growing field with many opportunities for those who want to pursue it professionally. The growth of this industry has been rapid in recent years, with more than 200 new products being marketed every year. In this article, we will look at the current trends in the industry and discuss how they affect marketers and consumers.
What is Biotechnology? Biotechnology is the application of biological processes and materials, including biochemistry, microbiology and molecular biology. Nobel-prize-winning chemist George Wald coined the term in 1949. Biotechnology is not the same as traditional biochemistry: it encompasses a diverse range of techniques we can use for industrial processing and research purposes. For example, it includes processes such as recombin…

Lung cancer is a major type of cancer in the world, with the highest morbidity and mortality among all malignant tumors. ALK-positive non-small cell lung cancer (ALK+ NSCLC) is a relatively rare and dangerous subtype, with patients suffering from a high incidence rate of brain metastases.
Lung cancer is a major type of cancer in the world, with the highest morbidity and mortality among all malignant tumors. ALK-positive non-small cell lung cancer (ALK+ NSCLC) is a relatively rare and dangerous subtype, with patients suffering from a high incidence rate of brain metastases. Statistics show that about 55% of ALK-positive advanced NSCLC patients will develop brain metastases during the treatment process, which is a serious challenge facing oncologists. In recent years, the application of targe…

Protein identification here refers to the accurate screening and identification of proteins using certain biochemical and physical methods. Traditional protein identification methods, including immunoblotting, comigration analysis of known or unknown proteins, and chemical sequencing of endopeptides, are complicated, time-consuming, and less accurate.
Methods in protein identification Protein identification here refers to the accurate screening and identification of proteins using certain biochemical and physical methods. Traditional protein identification methods, including immunoblotting, comigration analysis of known or unknown proteins, and chemical sequencing of endopeptides, are complicated, time-consuming, and less accurate.   Protein identification methods have evolved fro…

16S/18S/ITS amplicon sequencing has now been a well-established method. Due to its low cost, shorter cycle and low quality requirement of the sample, 16S/18S/ITS amplicon sequencing is widely used in the study of microorganisms.
16S/18S/ITS amplicon sequencing has now been a well-established method. Due to its low cost, shorter cycle and low quality requirement of the sample, 16S/18S/ITS amplicon sequencing is widely used in the study of microorganisms. 16S/18S/ITS amplicon sequencing reveals the species of microorganisms in environmental samples and their differences, relative abundance, population structure and evolutionary relationships. It plays an important role in the research of microorganisms and human health, agriculture and animal husbandry, environmental detection and t…