Articles
Whole genome sequencing looks at the whole genome of an organism, while targeted region sequencing looks at only the parts that are of interest. Targeted genome sequencing is a very sensitive and specific way to find SNPs, indels, CNVs, and large SVs.
What is targeted region sequencing? Whole genome sequencing looks at the whole genome of an organism, while targeted region sequencing looks at only the parts that are of interest. Targeted genome sequencing is a very sensitive and specific way to find SNPs, indels, CNVs, and large SVs. Compared to whole genome sequencing, targeted genome sequencing is more focused, economical, and effective. Furthermore, targeted regions can be sequenced at a much greater depth for a lower cost, which contributes to detecting rare variations. Whole exome seq…
What is targeted region sequencing? Whole genome sequencing looks at the whole genome of an organism, while targeted region sequencing looks at only the parts that are of interest. Targeted genome sequencing is a very sensitive and specific way to find SNPs, indels, CNVs, and large SVs. Compared to whole genome sequencing, targeted genome sequencing is more focused, economical, and effective. Furthermore, targeted regions can be sequenced at a much greater depth for a lower cost, which contributes to detecting rare variations. Whole exome seq…
As we all know, proteins play important roles in human bodies since all physiologic events are related to the structural or mechanical functions of certain proteins. Studying the synthesis process of proteins is a way to study the etiology, pathophysiology, diagnosis, and treatment of certain diseases.
As we all know, proteins play important roles in human bodies since all physiologic events are related to the structural or mechanical functions of certain proteins. Studying the synthesis process of proteins is a way to study the etiology, pathophysiology, diagnosis, and treatment of certain diseases. The human genome contains approximately 3 billion base pairs of DNA. Among them, only about 30 million base pairs of DNA carry the information for protein synthesis. This part of the genome is…
As we all know, proteins play important roles in human bodies since all physiologic events are related to the structural or mechanical functions of certain proteins. Studying the synthesis process of proteins is a way to study the etiology, pathophysiology, diagnosis, and treatment of certain diseases. The human genome contains approximately 3 billion base pairs of DNA. Among them, only about 30 million base pairs of DNA carry the information for protein synthesis. This part of the genome is…
Next-generation sequencing (NGS), which makes millions to billions of sequence reads at a fast rate, has greatly sped up genomics research. At the moment, Illumina, Ion Torrent/Life Technologies, 454/Roche, Pacific Bioscience, Nanopore, and GenapSys are all NGS platforms that can be used. They can produce reads of 100–10,000 bp in length, enabling sufficient coverage of the genome at a lower cost. But faced with the enormous amount of sequence data, how do we best deal with it? And what are the most appropriate computational methods and analysis tools for this purpose? In this review, we focus on the bioinformatics pipeline of whole exome sequencing (WES).
Next-generation sequencing (NGS), which makes millions to billions of sequence reads at a fast rate, has greatly sped up genomics resear…
Next-generation sequencing (NGS), which makes millions to billions of sequence reads at a fast rate, has greatly sped up genomics resear…
In competition with bacteriophages, bacteria and archaea have evolved unique ways of defending, which include the CRISPR/Cas systems and the immune systems of bacteria and archaea, which resist the invasion of foreign DNA or RNA and recognize the foreign invaders and cleave them for immune defense.
In competition with bacteriophages, bacteria and archaea have evolved unique ways of defending, which include the CRISPR/Cas systems and the immune systems of bacteria and archaea, which resist the invasion of foreign DNA or RNA and recognize the foreign invaders and cleave them for immune defense. CRISPR/Cas systems are now useful research tools that are easy to use and work well in the field of genetic engineering. In a CRISPR/Cas9-induced gene editing process, for example, the Cas9 enzy…
In competition with bacteriophages, bacteria and archaea have evolved unique ways of defending, which include the CRISPR/Cas systems and the immune systems of bacteria and archaea, which resist the invasion of foreign DNA or RNA and recognize the foreign invaders and cleave them for immune defense. CRISPR/Cas systems are now useful research tools that are easy to use and work well in the field of genetic engineering. In a CRISPR/Cas9-induced gene editing process, for example, the Cas9 enzy…
In this article, we explore 9 practical ways of winning and retaining top clients, from building a strong online presence to providing an innovative and evolving portfolio of services. Whether you are just starting out as a pharmaceutical recruitment agency or are looking to improve your current client retention rates, these tips will help you to stand out from your competition and build long-lasting relationships with your prospective and current clients.
As a Pharmaceutical recruitment agency, competition for top clients is tough, particularly in a time when business costs are rising, and many pharmaceutical companies are cutting back on their outsourcing as well as their hiring. In this article, we explore 9 practical ways of winning and retaining top clients, from building a strong onli…
As a Pharmaceutical recruitment agency, competition for top clients is tough, particularly in a time when business costs are rising, and many pharmaceutical companies are cutting back on their outsourcing as well as their hiring. In this article, we explore 9 practical ways of winning and retaining top clients, from building a strong onli…
01-Mar-2023
There is an ongoing trend in the pharmaceutical industry to outsource activities to external vendors. When such outsourcing affects GMDP-activities, and is therefore related to EU Good Manufacturing Practice (GMP) or Good Distribution Practice (GDP), defined regulatory requirements must be respected in the process of outsourcing.
There is an ongoing trend in the pharmaceutical industry to outsource activities to external vendors. When such outsourcing affects GMDP-activities, and is therefore related to EU Good Manufacturing Practice (GMP) or Good Distribution Practice (GDP), defined regulatory requirements must be respected in the process of outsourcing. One of the main misunderstandings that I observe in my role as an auditor and GxP-consultant is that outsourcing of activities does not m…
There is an ongoing trend in the pharmaceutical industry to outsource activities to external vendors. When such outsourcing affects GMDP-activities, and is therefore related to EU Good Manufacturing Practice (GMP) or Good Distribution Practice (GDP), defined regulatory requirements must be respected in the process of outsourcing. One of the main misunderstandings that I observe in my role as an auditor and GxP-consultant is that outsourcing of activities does not m…
A 2022 report by the Lancet Neurology Commission reveals traumatic brain injury is a global public health concern that affects 55 million people worldwide, according to Neuroscience News. Traumatic brain injuries (TBI) are severe incidents that often lead to disabilities and injury-related deaths.
A 2022 report by the Lancet Neurology Commission reveals traumatic brain injury is a global public health concern that affects 55 million people worldwide, according to Neuroscience News. Traumatic brain injuries (TBI) are severe incidents that often lead to disabilities and injury-related deaths. With increasing road accidents, sports injuries, and demand for non-invasive brain injury assessment and treatment procedures, the global traumatic brain injuries treatment market will reach over $2650 b…
A 2022 report by the Lancet Neurology Commission reveals traumatic brain injury is a global public health concern that affects 55 million people worldwide, according to Neuroscience News. Traumatic brain injuries (TBI) are severe incidents that often lead to disabilities and injury-related deaths. With increasing road accidents, sports injuries, and demand for non-invasive brain injury assessment and treatment procedures, the global traumatic brain injuries treatment market will reach over $2650 b…
A recent article in the Nursing Times revealed that only 21% of nurses and midwives in the UK were content with the number of employees present at their organisations. This information was plucked from the latest NHS Staff Survey, and appears only to represent the tip of the iceberg regarding healthcare professionals and their workplace satisfaction.
A recent article in the Nursing Times revealed that only 21% of nurses and midwives in the UK were content with the number of employees present at their organisations. This information was plucked from the latest NHS Staff Survey, and appears only to represent the tip of the iceberg regarding healthcare professionals and their workplace satisfaction. While this highlights a major need for change in this industry, there is thankfully a light at…
A recent article in the Nursing Times revealed that only 21% of nurses and midwives in the UK were content with the number of employees present at their organisations. This information was plucked from the latest NHS Staff Survey, and appears only to represent the tip of the iceberg regarding healthcare professionals and their workplace satisfaction. While this highlights a major need for change in this industry, there is thankfully a light at…
Bachem, a Swiss pharmaceutical company, has partnered with the SimplyNano project, educational experiment kits published by the non-profit foundation SimplyScience. This project aims to get young people excited about science and technology with the help of nano experiments.
The project involves the “SimplyNano 2”, which is a comprehensive nano-experimental kit for schools. Published by the SimplyScience Foundation and developed by Innovationsgesellschaft (a St. Gallen-based start-up), these kits are available free of charge for some secondary schools in northwestern Switzerland. By 2025, the SimplyNano 2 experiment kits should be available throughout Switzerland.
Bachem, a Swiss pharmaceutical company, has partnered with the SimplyNano project, educational experiment kits published by t…
Bachem, a Swiss pharmaceutical company, has partnered with the SimplyNano project, educational experiment kits published by t…
Decentralization allows for more diverse patient participation and improved data collection, leading to faster, more accurate results in clinical trials.
With the emergence of COVID-19, the Decentralization of Clinical Trials became necessary to comply with social distancing requirements while carrying out clinical research. Over the past few years, the clinical trial landscape has shifted its focus to patient-centric practices to promote patient engagement. But now as the pandemic is long gone, it is time to reflect on how DCT studies are genuinely addressing long-standing issues in research and development for sponsors, study teams, and of course, the patients! The digital shift in clinical trials has brought about the potential to improve both patient experience and clinical data qualit…
With the emergence of COVID-19, the Decentralization of Clinical Trials became necessary to comply with social distancing requirements while carrying out clinical research. Over the past few years, the clinical trial landscape has shifted its focus to patient-centric practices to promote patient engagement. But now as the pandemic is long gone, it is time to reflect on how DCT studies are genuinely addressing long-standing issues in research and development for sponsors, study teams, and of course, the patients! The digital shift in clinical trials has brought about the potential to improve both patient experience and clinical data qualit…
the pharmaceutical industry is undergoing significant changes, with emerging trends that will shape its future. Companies that stay up-to-date with these trends and invest in the right technologies and strategies will be better positioned to succeed in this dynamic and challenging industry. From personalized medicine and digital therapeutics to data analytics and AI, there are plenty of opportunities for innovation and growth in the years to come.
The pharmaceutical industry has undergone a lot of changes in recent years. With advancements in technology, changing consumer behavior, and increasing regulatory scrutiny, companies in this sector must stay up-to-date with the latest trends in order to remain competitive. In this article, we will explore the top emerging trends that are expected…
The pharmaceutical industry has undergone a lot of changes in recent years. With advancements in technology, changing consumer behavior, and increasing regulatory scrutiny, companies in this sector must stay up-to-date with the latest trends in order to remain competitive. In this article, we will explore the top emerging trends that are expected…
As the Life Sciences industry embraces a future that is data rather than document driven, companies have some practical questions to answer, such as who will make this happen? Thought leaders from BioNTech, Bayer, Iperion - a Deloitte business, and Beczek.COM recently came together for a Big Debate on the topic over video link. Generis COO Max Kelleher chaired the proceedings.
On the panel were: Dr. Melanie Ruppel, Senior Director Global Regulatory Affairs Regulatory Operations, BioNTech Vada A. Perkins, Executive Director, Regulatory Policy & Intelligence and Head of Regulatory Intelligence, Bayer Pharmaceuticals Frits Stulp, Managing Director, Iperion - a Deloitte business Preeya Beczek, Director & Independent Regulatory Affairs Expert, Beczek.COM Frits Stulp of Iperion – a Delo…
On the panel were: Dr. Melanie Ruppel, Senior Director Global Regulatory Affairs Regulatory Operations, BioNTech Vada A. Perkins, Executive Director, Regulatory Policy & Intelligence and Head of Regulatory Intelligence, Bayer Pharmaceuticals Frits Stulp, Managing Director, Iperion - a Deloitte business Preeya Beczek, Director & Independent Regulatory Affairs Expert, Beczek.COM Frits Stulp of Iperion – a Delo…
The global clinical trials market was estimated to be worth $38.7 billion in 2021 and is expected to reach £52 billion by 2026. In this article, we look at the top 12 CROs in the world, highlighting the companies driving this considerable growth and accelerating research and development across the globe.
The global clinical trials market was estimated to be worth $38.7 billion in 2021 and is expected to reach £52 billion by 2026. In this article, we look at the top 12 CROs in the world, highlighting the companies driving this considerable growth and accelerating research and development across the globe. ICON Recognised as the world’s largest and most comprehensive CRO powered by Healthcare Intelligence, ICON provides outsourced development and commercialisation services to pharmaceutical,…
The global clinical trials market was estimated to be worth $38.7 billion in 2021 and is expected to reach £52 billion by 2026. In this article, we look at the top 12 CROs in the world, highlighting the companies driving this considerable growth and accelerating research and development across the globe. ICON Recognised as the world’s largest and most comprehensive CRO powered by Healthcare Intelligence, ICON provides outsourced development and commercialisation services to pharmaceutical,…
Cell and gene therapy clinical research is a rapidly growing field that holds great promise for the treatment of a wide range of diseases. These therapies involve the use of living cells or genes to treat or prevent diseases and have the potential to revolutionize the way we approach healthcare.
Changing Cell & Gene Therapy Landscape and Implications on Clinical Trials By Elizabeth Dugan, Director, Business Development on December, 20 2022 Cell & Gene Therapy Background Cell and gene therapy clinical research is a rapidly growing field that holds great promise for the treatment of a wide range of diseases. These therapies involve the use of living cells or genes to treat or prevent diseases and have the potential to revolutionize the way we approach healthcare. One key as…
Changing Cell & Gene Therapy Landscape and Implications on Clinical Trials By Elizabeth Dugan, Director, Business Development on December, 20 2022 Cell & Gene Therapy Background Cell and gene therapy clinical research is a rapidly growing field that holds great promise for the treatment of a wide range of diseases. These therapies involve the use of living cells or genes to treat or prevent diseases and have the potential to revolutionize the way we approach healthcare. One key as…
After practical supply chain issues in 2022, added to the impact of continued medicinal/device innovation, 2023 will bring new regulatory changes linked to process digitalisation and automation. REPHINE’s Dr. Eduard Cayón discusses the implications for Quality control.
Never before has the Life Sciences industry needed a robust manufacturing and supply chain Quality backbone as it does now. Advanced markets such as Europe and North America are already well used to strict controls and audits, but standards are being raised right around the world now - from South America to the Middle East and Asia. The pandemic, the war in Ukraine, and innovation-based disruption at the core of the industry have contributed to a renewed focus on supply chain security and quality. The upshot is that manufactu…
Never before has the Life Sciences industry needed a robust manufacturing and supply chain Quality backbone as it does now. Advanced markets such as Europe and North America are already well used to strict controls and audits, but standards are being raised right around the world now - from South America to the Middle East and Asia. The pandemic, the war in Ukraine, and innovation-based disruption at the core of the industry have contributed to a renewed focus on supply chain security and quality. The upshot is that manufactu…
21-Feb-2023
The Clinical & Contract Research Association (CCRA) recognises that, as a sector, we are currently facing a number of challenges, not the least of these being that the UK Pharmaceutical industry is heading for a very serious staff shortage which will push up costs with concomitant loss of competitiveness. Global Contract Research Organisations are getting over the problem, in the short term, by offering large signing–on inducements and poaching experienced staff from competitors.
The Clinical & Contract Research Association (CCRA) recognises that, as a sector, we are currently facing a number of challenges, not the least of these being that the UK Pharmaceutical industry is heading for a very serious staff shortage which will push up costs with concomitant loss of competitiveness. Glo…
The Clinical & Contract Research Association (CCRA) recognises that, as a sector, we are currently facing a number of challenges, not the least of these being that the UK Pharmaceutical industry is heading for a very serious staff shortage which will push up costs with concomitant loss of competitiveness. Glo…
21-Feb-2023
As the Life science sector evolves, being on top of new trends and regulations is essential for success. By navigating the complexities of risk-based systems, leveraging cutting-edge technology such as artificial intelligence (AI), and prioritizing their supply chains, companies in Ireland can remain at the forefront of the industry in 2023." That's according to Jane Lyons, Country Manager, PharmaLex Ireland, the leading provider of specialised services to the Life Sciences industry worldwide.
As the Life science sector evolves, being on top of new trends and regulations is essential for success. By navigating the complexities of risk-based systems, leveraging cutting-edgetechnology such as artificial intelligence (AI), and prioritizing their supply chains, companies in Ireland can remain a…
As the Life science sector evolves, being on top of new trends and regulations is essential for success. By navigating the complexities of risk-based systems, leveraging cutting-edgetechnology such as artificial intelligence (AI), and prioritizing their supply chains, companies in Ireland can remain a…
Clinical research Courses In Pune is a rapidly growing field that involves the study of health and disease in human populations. It is a critical component of the healthcare industry, and the demand for skilled professionals in this field is high.
Clinical research Courses In Pune is a rapidly growing field that involves the study of health and disease in human populations. It is a critical component of the healthcare industry, and the demand for skilled professionals in this field is high. A career in clinical research can be incredibly rewarding, as it offers the opportunity to make a real difference in people's lives. If you're interested in pursuing a career in clinical research, taking a course can provide you with the knowledge and skills you need to succeed. In this post, we will dis…
Clinical research Courses In Pune is a rapidly growing field that involves the study of health and disease in human populations. It is a critical component of the healthcare industry, and the demand for skilled professionals in this field is high. A career in clinical research can be incredibly rewarding, as it offers the opportunity to make a real difference in people's lives. If you're interested in pursuing a career in clinical research, taking a course can provide you with the knowledge and skills you need to succeed. In this post, we will dis…
In today’s job market, having a well-crafted CV can make all the difference when it comes to landing your next pharma job. In this article, we’ve outlined 11 things pharma and life science recruiters will be looking for in a standout CV, from contact details to personality.
In today’s job market, having a well-crafted CV can make all the difference when it comes to landing your next pharma job. In this article, we’ve outlined 11 things pharma and life science recruiters will be looking for in a standout CV, from contact details to personality… Contact Details Include your contact details clearly at the top of your CV to make it as easy as possible for the person reading to get in touch with you. Always include: Full name Telephone number Email address You can also include your LinkedIn/we…
In today’s job market, having a well-crafted CV can make all the difference when it comes to landing your next pharma job. In this article, we’ve outlined 11 things pharma and life science recruiters will be looking for in a standout CV, from contact details to personality… Contact Details Include your contact details clearly at the top of your CV to make it as easy as possible for the person reading to get in touch with you. Always include: Full name Telephone number Email address You can also include your LinkedIn/we…
Defibrillators save lives – and smart defibrillator monitoring ensures this important equipment is locatable and in good working order in an emergency. From 20 January 2023, defibrillators have become mandatory in all state-funded schools. Research has shown that the use of a defibrillator for three to five minutes from the time of a cardiac arrest increases the chance of survival by 40%.
Defibrillators save lives – and smart defibrillator monitoring ensures this important equipment is locatable and in good working order in an emergency. From 20 January 2023, defibrillators have become mandatory in all state-funded schools. Research has shown that the use of a defibrillator for three to five minutes from the time of a cardiac arrest increases the chance of survival by 40%. The availability…
Defibrillators save lives – and smart defibrillator monitoring ensures this important equipment is locatable and in good working order in an emergency. From 20 January 2023, defibrillators have become mandatory in all state-funded schools. Research has shown that the use of a defibrillator for three to five minutes from the time of a cardiac arrest increases the chance of survival by 40%. The availability…
