Articles
Cancer Res: Scientists identify potential new targets for cancer immunotherapy: GARP According to the American Cancer Society, colorectal cancer is the third leading cause of cancer death in men and women. Although significant progress has been made in the treatment of such cancers, the 5-year survival rate of colorectal cancer patients is only 12%. Recently, in a research report published in Cancer Research, scientists from the University of South Carolina Medical University found a potential new target for colorectal cancer immunotherapy. Similar to PD-1, GARP is a special protein expressed on the surface of immune cells. R…
In 2016, the global contract packaging market was worth $26.54 billion, and is expected to reach $47.28 billion by 2022. This compound annual growth rate (CAGR) of 10.1 per cent is expected to be driven largely by growing demand for pharmaceutical contract packaging. Here, Dale Pittock, sales director of pharmacy packaging provider Valley Northern, explains how contract packaging can support pharmaceutical innovation. NASDAQ’s Globe Newswire reported the predicted global growth for the contract packaging sector in April…
Enzymes are involved in the formation and composition of every cell in the body. Thus they also control the working of every organ and even the brain - the control center. They are involved in the breakdown, absorption, distribution and circulation of various nutrients entering the body. Overall, it would be sufficient to say that life would be non-existent without enzymes. How many of us have ever been concerned about our gut health and how enzymes affect the digestive process. It obviously is the last thing that one would care about after a whole busy day and the same regular stressing lifestyle. People will not…
Previously, early detection of Alzheimer’s disease seems to be very difficult as it takes years for the symptoms to become obvious. Fortunately, scientists have found a way to detect blood in order to accurately identify Alzheimer's disease several years in advance. This has made early intervention possible for people who have Alzheimer's disease but yet haven’t fully realized such a fact. The struggle against Alzheimer's has been on-going for over one hundred years, but so far we have not found a way to control or reverse cognitive decline and me…
As proof-of-concept projects begin to highlight IDMP’s different real-world use cases, and illustrate the potential benefits, stakeholders must come together and give greater emphasis to patients in 2020– which starts with giving them a seat at the table, says Frits Stulp of Iperion Life Sciences Consultancy. If 2019 was the year of progress around common definitions for medicinal substances, in an IDMP context, then 2020 needs to be the year of product-related data progress – and of p…
Enzymes are molecules, especially proteins that help to accelerate biochemical reactions by interacting with components (reactants and products) without permanently changing them. This promotion process is called catalysis, and accordingly, the enzyme is recognized as a catalyst. Like many participants in the microbiology community, the names of enzymes can be lengthy and cumbersome, and almost all names end with "-ase". However, if you are familiar with the formal system of enzyme naming, you can unravel many mysteries about the function of a given enzyme without knowin…
Over recent years, research into the causes and effects of ageing has intensified. This is largely driven by an ageing population and the consequent acute need to keep people fit and healthy as they get older. Fail to do so, and we risk placing even greater strain on already staggering healthcare systems. Recent advancements in the fields of technology and personalised nutrition are laying the foundations to enable better self-care among older adults. Transforming these quickly into effect…
Enzymes are vital to the human body. Without enzymes, cells in our body will not be able to carry out chemical reactions because the energy required is too grate. Enzymes reduce the activation energy response that needs to occur, thus allowing our body to perform a series of reactions at low temperatures. Enzymes are the proteins that are needed in our system. Without them, we will not be able to survive. The name of the enzyme depends on the action of the enzyme. Lipases break down fatty acids (lipids), and proteases break down proteins. Se…
Research highlights top investment areas for digital transformation in UK healthcare Digitalisation of healthcare provision is widely acknowledged as an enabler to help healthcare organisations cope with rising demand across the globe New research from Siemens Financial Services identifies three priority areas for investment in digital transformation in healthcare and the expected capital investment required over the next five years These are: New generation (digitalised and/or mobile) diagnostics $1.5 billion (£1.17 billion); Remote access and com…
Opioid and drug misuse has profound economic and health consequences on Americans, including a rise in certain infectious diseases throughout our nation. Drug misuse is linked to marked increases in acute hepatitis C infections, increases in acute hepatitis B infections in some states, and hepatitis A outbreaks in 30 states since 2016. Injection drug use has also been associated with local HIV outbreaks in multiple areas of the country. In 2017, approximately 9% of new HIV cases in the United States were linked to injection drug use, threatening prior progress made in reducing HIV. The data show that we cannot look at…
Global Edition Focus on Patient Experience Patients still facing big obstacles getting their own health data Despite HIPAA's right of access rule, and CMS and ONC prioritizing consumer access in their forthcoming 21st Century Cures regs, a new scorecard shows that providers have work to do. By Mike Miliard November 14, 2019 09:41 AM "Patients need their records, and it shouldn't be hard to get them," says Deven McGraw, chief regulatory officer at Ciitizen, a startup founded in 2017 that develops tools to help patien…
The industrial enzyme production industry has experienced rapid development for more than half a century, and has now formed a dynamic high-tech industry to maintain sustained high-speed development. In the past 10 years, some fundamental changes have taken place in production technology. With the continuous advancement and maturity…
Alzheimer's disease is one of the most common neurodegenerative disorder for the elderly. Early-onset Alzheimer's is rare that develops before age 65, primarily genetically influenced. Generally, the patients…
Overactive neurons in specific regions of the brain are thought to be early disturbances of Alzheimer's disease. In a new study, researchers from the Technical University of Munich, Germany, were the first to explain the causes and mechanisms of this early neurological dysfunction. They found that the excitatory neurotransmitter glutamate persisted for too long in the vicinity of active neurons. This causes these neurons to suffer from pathological over-stimulation, which is likely to be a key factor in learning and memory loss in patients with Alzheimer'…
In recent years, many new therapy approaches has emerged in the field of cancer treatment. The monoclonal antibody drugs approved each year is on the rise, and the immunotherapy represented by anti-PD-1/PD-L1 antibody is rewriting the pattern of cancer treatment. In addition, cell therapy, represented by CAR-T therapy, is officially on the stage, bringing a totally different treatment to blood cancer. Facing these endless stream of advanced therapies, traditional small mol…
Enzymes can be utilized in numerous fields, such as enzymes for diagnostics and enzymes for cancer treatment. Due to the action of the enzyme, the chemical reaction in the organism can be effectively carried out under very mild conditions, enabling the organism to digest food, absorb nutrients, and maintain visceral functions such as anti-inflammatory detoxification, metabolism, immunity, energy production, blood promotion, circulation, etc. The body contains a variety of enzymes that control many metabolic processes such as metabolism, nutri…
People get all the nutrients and energy they need through food. A reasonable diet and adequate nutrition can improve the health of a generation, prevent a variety of diseases, prolong life and improve the physical fitness of the entire nation. Unreasonable diet, excessive or insufficient nutrition will bring different degrees of harm to health. Overeating can lead to obesity, diabetes, cholelithiasis, hyperlipidemia, high blood pressure and other diseases due to overnutrition, and even induce mesothelioma, such…
Power to the patient: the value of longitudinal data Steve Bradley, Group Managing Director, Cegedim UK, outlines how data holds the key to better patient care. It’s no secret that the digitisation of healthcare services and smarter use of patient data can have a transformative impact on the NHS. In the past five years, re…
Reducing the cost of SMBG test strips With the latest news from NHS England highlighting that £700 million cost savings have…
Underground criminals producing counterfeit goods have become alarmingly good at replicating manufacturers’ branding and are infiltrating the market. That’s a significant problem for both manufacturers and consumers, and the scale of the issue is rising. Counterfeit products can present terrifying dangers. These falsified products are then made to look authentic thanks to replicated labelling that app…