Articles

Anti-aging is intensively discussed nowadays. This article talks about the factors and biomarkers that relates to aging.
Exercise and aging Although lots of money and efforts have been invested into drug development, no drug is found to be effective in combatting aging. It is important to note that exercise is a truly effective anti-aging measure. In the absence of suitable treatments for age-related dysfunction, exercise is currently the only intervention that shows significant efficacy, reducing the incidence of age-related diseases, improving quality of life, and even increasing the life expectancy of the human body. Even moderate exercise can bring seeable benefits. Although key molecular participants mediating the protective effects of exercise on age-related diseases are not yet known…

With the society becoming ever more egalitarian, there’s an increasing concern among dads at work regarding policies that support work-life balance.
But, when it comes to offering support to new parents, much focus is on relieving new mothers. We see companies all over the world boasting of their family-friendly policies. They’re going out of the way to provide young mothers with paid maternity leave, in-house day-care, nursing breaks, part-time and/or remote work options, and more. But, what about new dads? Are they getting the same level of support? Why does it even matter? In this article, we’ll take a look at the current situation of work-life balance among working dads, focussed particularly in the biotech and pharmaceutical industries. We’ll identify some of the key factors that dist…

. The first ever clinical study evaluating combined transcranial direct current stimulation (tDCS) and behaviour therapy could point to a new treatment for depression. The clinical pilot study is being undertaken by Flow Neuroscience, Europe’s first, and only...
London, UK. The first ever clinical study evaluating combined transcranial direct current stimulation (tDCS) and behaviour therapy could point to a new treatment for depression. The clinical pilot study is being undertaken by Flow Neuroscience, Europe’s first, and only, medically approved, at-home treatment for depression, which comprises a tDCS headset device and behaviour therapy app. The results will help the process of getting the Flow device reimbursed by healthcare providers, including the UK’s NHS. The independent study will…

As new device identification and traceability measures become compulsory in 2020 under MDR, Kallik’s Bob Tilling explores the outstanding labelling challenges for manufacturers.
As new device identification and traceability measures become compulsory in 2020 under MDR, Kallik’s Bob Tilling explores the outstanding labelling challenges for manufacturers. From May 2020, new medical devices sold in the EU must comply with new Medical Device Regulation (MDR) requirements. So how well prepared are manufacturers as the deadline approaches, and what challenges remain? 1.      Starting from scratch: the pain of playing catch-up Many medical device manufacturers have been caught off-guard by just how demanding this wholescale process change can be. Preparing for MDR has been…

In December 2016, a pharmacist in Northern Ireland made a tragic error when he fatally dispensed propranolol to a patient who was prescribed prednisolone. It was revealed that the two boxes were side-by-side on the pharmacy’s shelf, with similar branding and packaging. Such simple slip-ups can result in devastation and highlight packaging’s crucial role in keeping patients safe.
In December 2016, a pharmacist in Northern Ireland made a tragic error when he fatally dispensed propranolol to a patient who was prescribed prednisolone. It was revealed that the two boxes were side-by-side on the pharmacy’s shelf, with similar branding and packaging. Such simple slip-ups can result in devastation and highlight packaging’s crucial role in keeping patients safe. Here, Oliver Pittock managing direc…

Immunotherapy has proven to be effective in treating a variety of cancers. This article sorts out some of the latest research findings on cancer immunotherapy.
Cancer Res: Scientists identify potential new targets for cancer immunotherapy: GARP  According to the American Cancer Society, colorectal cancer is the third leading cause of cancer death in men and women. Although significant progress has been made in the treatment of such cancers, the 5-year survival rate of colorectal cancer patients is only 12%. Recently, in a research report published in Cancer Research, scientists from the University of South Carolina Medical University found a potential new target for colorectal cancer immunotherapy. Similar to PD-1, GARP is a special protein expressed on the surface of immune cells. R…

In 2016, the global contract packaging market was worth $26.54 billion, and is expected to reach $47.28 billion by 2022. This compound annual growth rate (CAGR) of 10.1 per cent is expected to be driven largely by growing demand for pharmaceutical contract packaging.
In 2016, the global contract packaging market was worth $26.54 billion, and is expected to reach $47.28 billion by 2022. This compound annual growth rate (CAGR) of 10.1 per cent is expected to be driven largely by growing demand for pharmaceutical contract packaging. Here, Dale Pittock, sales director of pharmacy packaging provider Valley Northern, explains how contract packaging can support pharmaceutical innovation.   NASDAQ’s Globe Newswire reported the predicted global growth for the contract packaging sector in April…

Enzymes are involved in the formation and composition of every cell in the body. Thus they also control the working of every organ and even the brain - the control center.
Enzymes are involved in the formation and composition of every cell in the body. Thus they also control the working of every organ and even the brain - the control center. They are involved in the breakdown, absorption, distribution and circulation of various nutrients entering the body. Overall, it would be sufficient to say that life would be non-existent without enzymes.   How many of us have ever been concerned about our gut health and how enzymes affect the digestive process. It obviously is the last thing that one would care about after a whole busy day and the same regular stressing lifestyle. People will not…

Scientists have found a way to detect blood in order to accurately identify Alzheimer's disease several years in advance. This has made early intervention possible for people who have Alzheimer's disease but yet haven’t fully realized such a fact.
Previously, early detection of Alzheimer’s disease seems to be very difficult as it takes years for the symptoms to become obvious. Fortunately, scientists have found a way to detect blood in order to accurately identify Alzheimer's disease several years in advance. This has made early intervention possible for people who have Alzheimer's disease but yet haven’t fully realized such a fact. The struggle against Alzheimer's has been on-going for over one hundred years, but so far we have not found a way to control or reverse cognitive decline and me…

As proof-of-concept projects begin to highlight IDMP’s different real-world use cases, and illustrate the potential benefits, stakeholders must come together and give greater emphasis to patients in 2020– which starts with giving them a seat at the table, says Frits Stulp of Iperion Life Sciences Consultancy.
As proof-of-concept projects begin to highlight IDMP’s different real-world use cases, and illustrate the potential benefits, stakeholders must come together and give greater emphasis to patients in 2020– which starts with giving them a seat at the table, says Frits Stulp of Iperion Life Sciences Consultancy. If 2019 was the year of progress around common definitions for medicinal substances, in an IDMP context, then 2020 needs to be the year of product-related data progress – and of p…

Enzymes work in a mild environment, similar to the physical environment of living organisms. Enzymes support life by synthesizing and degrading the materials that make up the components of the organism and creating energy.
Enzymes are molecules, especially proteins that help to accelerate biochemical reactions by interacting with components (reactants and products) without permanently changing them. This promotion process is called catalysis, and accordingly, the enzyme is recognized as a catalyst. Like many participants in the microbiology community, the names of enzymes can be lengthy and cumbersome, and almost all names end with "-ase". However, if you are familiar with the formal system of enzyme naming, you can unravel many mysteries about the function of a given enzyme without knowin…

Over recent years, research into the causes and effects of ageing has intensified. This is largely driven by an ageing population and the consequent acute need to keep people fit and healthy as they get older. Fail to do so, and we risk placing even greater strain on already staggering healthcare systems.
Over recent years, research into the causes and effects of ageing has intensified. This is largely driven by an ageing population and the consequent acute need to keep people fit and healthy as they get older. Fail to do so, and we risk placing even greater strain on already staggering healthcare systems. Recent advancements in the fields of technology and personalised nutrition are laying the foundations to enable better self-care among older adults. Transforming these quickly into effect…

Enzymes reduce the activation energy response that needs to occur, thus allowing our body to perform a series of reactions at low temperatures. Enzymes are the proteins that are needed in our system. Without them, we will not be able to survive.
Enzymes are vital to the human body. Without enzymes, cells in our body will not be able to carry out chemical reactions because the energy required is too grate. Enzymes reduce the activation energy response that needs to occur, thus allowing our body to perform a series of reactions at low temperatures. Enzymes are the proteins that are needed in our system. Without them, we will not be able to survive. The name of the enzyme depends on the action of the enzyme. Lipases break down fatty acids (lipids), and proteases break down proteins.   Se…

Siemens Financial Services (SFS) has released new research identifying the priority investment areas for digital transformation in healthcare, the size of the investment challenge, and how healthcare organisations can manage that challenge
Research highlights top investment areas for digital transformation in UK healthcare  Digitalisation of healthcare provision is widely acknowledged as an enabler to help healthcare organisations cope with rising demand across the globe New research from Siemens Financial Services identifies three priority areas for investment in digital transformation in healthcare and the expected capital investment required over the next five years These are: New generation (digitalised and/or mobile) diagnostics $1.5 billion (£1.17 billion); Remote access and com…

Summary: Opioid and drug misuse has profound economic and health consequences on Americans, including a rise in certain infectious diseases throughout our nation.
Opioid and drug misuse has profound economic and health consequences on Americans, including a rise in certain infectious diseases throughout our nation. Drug misuse is linked to marked increases in acute hepatitis C infections, increases in acute hepatitis B infections in some states, and hepatitis A outbreaks in 30 states since 2016. Injection drug use has also been associated with local HIV outbreaks in multiple areas of the country. In 2017, approximately 9% of new HIV cases in the United States were linked to injection drug use, threatening prior progress made in reducing HIV. The data show that we cannot look at…

Despite HIPAA's right of access rule, and CMS and ONC prioritizing consumer access in their forthcoming 21st Century Cures regs, a new scorecard shows that providers have work to do.
  Global Edition Focus on Patient Experience Patients still facing big obstacles getting their own health data Despite HIPAA's right of access rule, and CMS and ONC prioritizing consumer access in their forthcoming 21st Century Cures regs, a new scorecard shows that providers have work to do. By Mike Miliard November 14, 2019 09:41 AM   "Patients need their records, and it shouldn't be hard to get them," says Deven McGraw, chief regulatory officer at Ciitizen, a startup founded in 2017 that develops tools to help patien…

Along with the economic tide of global economic integration, the world biotechnology industry is also adjusting the industrial structure and product structure on a global scale, covering detergents, textiles, alcohol, spirits, beer, monosodium glutamate, organic acids, starch sugar, In the industrial fields of pharmaceutical, tanning, feed, paper, juice, meat, eggs, beans, milk, and pasta processing, the industrial added value has exceeded 100 billion dollars.
The industrial enzyme production industry has experienced rapid development for more than half a century, and has now formed a dynamic high-tech industry to maintain sustained high-speed development. In the past 10 years, some fundamental changes have taken place in production technology. With the continuous advancement and maturity…

Alzheimer's disease is one of the most common neurodegenerative disorder for the elderly. Early-onset Alzheimer's is rare that develops before age 65, primarily genetically influenced. Generally, the patients older than age 65 who account for a large proportion among the whole patients suffer from late-onset Alzheimer’s. The patients with late-onset Alzheimer’s have to fight against a series of frustrating symptoms, such as memory loss, poor language skills, unstable emotions, and no self-care ability, which may lead to numerous troubles or burden for themselves and the family members.
Alzheimer's disease is one of the most common neurodegenerative disorder for the elderly. Early-onset Alzheimer's is rare that develops before age 65, primarily genetically influenced. Generally, the patients…

For quite a long time, it remains a puzzle as to what causes Alzheimer's disease. There are different opinions on this matter. Previously, tau and β-amyloid are to blame. In this article, let's see what new findings have been discovered.
Overactive neurons in specific regions of the brain are thought to be early disturbances of Alzheimer's disease. In a new study, researchers from the Technical University of Munich, Germany, were the first to explain the causes and mechanisms of this early neurological dysfunction. They found that the excitatory neurotransmitter glutamate persisted for too long in the vicinity of active neurons. This causes these neurons to suffer from pathological over-stimulation, which is likely to be a key factor in learning and memory loss in patients with Alzheimer'…

Small-molecule inhibitors are a well-established class of potential useful drugs. Our products are included in all kinds of fields of Medical and Pharmaceutical research, such as Neurological Disease, Cancer, Metabolic Disease and so on. This article deals with the most concerned questions about small molecule inhibitors.
In recent years, many new therapy approaches has emerged in the field of cancer treatment. The monoclonal antibody drugs approved each year is on the rise, and the immunotherapy represented by anti-PD-1/PD-L1 antibody is rewriting the pattern of cancer treatment. In addition, cell therapy, represented by CAR-T therapy, is officially on the stage, bringing a totally different treatment to blood cancer. Facing these endless stream of advanced therapies, traditional small mol…