Biotech - Articles
Enzymes are biocatalysts produced by living cells in organisms, most of which are usually globular proteins. These enzymes can effectively catalyze various biochemical reactions and promote the metabolism of organisms under normal human conditions. Life activities such as digestion, absorption, breathing, exercise, and reproduction are all enzymatic reactions. Therefore, enzymes are the basis for cell survival. There are many kinds of enzymes in the human body, and more tha…
Earlier this year the European Medicines Agency updated its guidelines, clarifying how to maintain supply of UK-registered products in Europe following December 31. Here, Cecilia Avram, Senior Regulatory Affairs Manager at Arriello, assesses what needs to change. After months of Covid-related distractions, Brexit is back in the headlines - demanding new attention to how the life sciences industry will maintain cross-border product movement and manage regulatory administration from January 1. Updated guidelines for pharmaceuticals…
By Sharon Rindsland, Senior Manual Handling Co-ordinator, East Kent Hospitals Since 1975 worldwide obesity has nearly tripled. In 2016, more than 1.9 billion adults were classed as being overweight, of these 650 million were obese. However, this doesn’t just apply to adults, over 340 million children and adolescents aged 5-19 were overweight or obese in 2016 . Unfortunately, complications related to obesity continue post-mortem. Nursing staff and mortuary technicians often face these complications when processing and transferring overweight patients. Issues such as loss of dignity for the patient, difficulty transferring patients resulting in musculoskeletal injuries (MSI) for staff, inc…
Catalysis Enzymes are a class of biological catalysts. They govern many catalytic processes such as metabolism, nutrition, and energy conversion of organisms. Most of the reactions closely related to life processes are enzyme-catalyzed reactions. These properties of the enzyme enable the intricate process of material metabolism in the cell to proceed in an orderly manner, and to adapt material metabolism to normal physiological functions. If an enzyme is defective due to genetic defects, or the enzyme activity is weakened by other reasons, it can caus…
In order to carry out various life activities, the organism must obtain energy and produce new substances needed for its growth. By ingesting nutrients, organisms produce energy through decomposition; or produce new substances through synthesis. In organisms, nutrition molecules participate in various decomposition and synthesis reactions, collectively known as metabolism. Any substance has more or less energy. When a substance changes through a chemical reaction, it will take a long time to complete under the condition of no external force. This long-term reaction is not enough to maintain life activity of the organism. Therefore, organisms have developed…
Enzymes are involved in the formation and composition of every cell in the body. Thus they also control the working of every organ and even the brain - the control center. They are involved in the breakdown, absorption, distribution and circulation of various nutrients entering the body. Overall, it would be sufficient to say that life would be non-existent without enzymes. How many of us have ever been concerned about our gut health and how enzymes affect the digestive process. It obviously is the last thing that one would care about after a whole busy day and the same regular stressing lifestyle. People will not…
Enzymes are molecules, especially proteins that help to accelerate biochemical reactions by interacting with components (reactants and products) without permanently changing them. This promotion process is called catalysis, and accordingly, the enzyme is recognized as a catalyst. Like many participants in the microbiology community, the names of enzymes can be lengthy and cumbersome, and almost all names end with "-ase". However, if you are familiar with the formal system of enzyme naming, you can unravel many mysteries about the function of a given enzyme without knowin…
Enzymes are vital to the human body. Without enzymes, cells in our body will not be able to carry out chemical reactions because the energy required is too grate. Enzymes reduce the activation energy response that needs to occur, thus allowing our body to perform a series of reactions at low temperatures. Enzymes are the proteins that are needed in our system. Without them, we will not be able to survive. The name of the enzyme depends on the action of the enzyme. Lipases break down fatty acids (lipids), and proteases break down proteins. Se…
The industrial enzyme production industry has experienced rapid development for more than half a century, and has now formed a dynamic high-tech industry to maintain sustained high-speed development. In the past 10 years, some fundamental changes have taken place in production technology. With the continuous advancement and maturity…
Alzheimer's disease is one of the most common neurodegenerative disorder for the elderly. Early-onset Alzheimer's is rare that develops before age 65, primarily genetically influenced. Generally, the patients…
Enzymes can be utilized in numerous fields, such as enzymes for diagnostics and enzymes for cancer treatment. Due to the action of the enzyme, the chemical reaction in the organism can be effectively carried out under very mild conditions, enabling the organism to digest food, absorb nutrients, and maintain visceral functions such as anti-inflammatory detoxification, metabolism, immunity, energy production, blood promotion, circulation, etc. The body contains a variety of enzymes that control many metabolic processes such as metabolism, nutri…
People get all the nutrients and energy they need through food. A reasonable diet and adequate nutrition can improve the health of a generation, prevent a variety of diseases, prolong life and improve the physical fitness of the entire nation. Unreasonable diet, excessive or insufficient nutrition will bring different degrees of harm to health. Overeating can lead to obesity, diabetes, cholelithiasis, hyperlipidemia, high blood pressure and other diseases due to overnutrition, and even induce mesothelioma, such…
The growth and reproduction of life, birth and death, and metabolism are all related to enzymes. Without the catalysis of enzymes, humans can't even carry out the most basic life activities, such as food digestion, oxygen breathing, etc., let alone other problems. In fact, almost all kinds of reactions occurring in living organisms are carried out by enzyme catalysis. We can even say that the existe…
m the physiological point of view, most microalgae should have the ability to grow heterotrophically. The growth process of microalgae using organic matter mainly has two forms: one is that microalgae can use organic matter to carry out heterotrophic growth under completely dark conditions, and there is no difference between the general chemical heterotrophic organisms; another form is that microalgae us…
With the great insights on enzyme catalytic mechanisms, biosynthesis, structure, and the rapid development of physical and chemical technology, the rapid rise of molecular enzymology and enzyme engineering has been promoted, making enzyme engineering an important role in bioengineering. In fact, it is an epoch-making leap in human understanding of enzymes, transformation of new enzymes and extensive use of enzymes. The microbial enzyme source is the main source of enzyme engineering research. Biodiversit…
Healthy life expectancy, which is the number of years lived in good health, has not increased as quickly as life expectancy in recent decades, which means people are living more years in poor health. The UK Government’s Industrial Strategy contains a target of “ensur[ing] that people can enjoy at least five extra healthy, independent years of life by 2035, while narrowing the gap between the experience of the richest and poorest”. This new report, which is the result of a project involving an expert panel of researchers, funders and public health policy makers, outlines co…
The severe side effects of conventional chemotherapeutic treatments can’t be ignored since in most cases, the valid drug dose that can remove the tumor are too toxic for patients. To solve the limitations, the antibody drug conjugates (ADCs) have emerged consisting of tumor-selective antibody-linked drugs, with the potential to significantly broaden the therapeutic range. Antibody-drug conjugates (ADCs), the focus o…
The interpretation of enzymes in the modern industry certainly does not refer to yeast, but to proteins with catalytic functions. As a natural catalyst, enzymes promote various chemical reactions in cells and play a vital role in the existence of living organisms. From the concept of enzymes, to the mature industrial enzyme production, it has probably gone through 130-40 years. The Greek translation of the enzyme is "in yeast", meaning from yeast. In 1897, after the methods of disruption for yeast, the extract obtained had the…
In general, polyclonal antibodies are made by collecting blood from an immunized animal stimulated with a target antigen, which can be provided all the time as…
Bispecific antibody (BsAb) is an artificially engineered antibody that can simultaneously bind two specific epitopes or target proteins with some special biological functions, such as directly targeting effector cells to tumor cells, to enhance cytotoxicity, improve antibody selectivity a…