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Many complex reactions occurred during the whole process. It can be said that without enzymes, biological metabolism will not continue, and the entire colorful biological community in nature will disappear. Now we know the importance of enzymes in organisms, which is why enzymes can be used for clinical diagnosis.
Enzymes are biocatalysts produced by living cells in organisms, most of which are usually globular proteins. These enzymes can effectively catalyze various biochemical reactions and promote the metabolism of organisms under normal human conditions. Life activities such as digestion, absorption, breathing, exercise, and reproduction are all enzymatic reactions. Therefore, enzymes are the basis for cell survival.   There are many kinds of enzymes in the human body, and more tha…
Earlier this year the European Medicines Agency updated its guidelines, clarifying how to maintain supply of UK-registered products in Europe following December 31. Here, Cecilia Avram, Senior Regulatory Affairs Manager at Arriello, assesses what needs to change.
Earlier this year the European Medicines Agency updated its guidelines, clarifying how to maintain supply of UK-registered products in Europe following December 31. Here, Cecilia Avram, Senior Regulatory Affairs Manager at Arriello, assesses what needs to change.   After months of Covid-related distractions, Brexit is back in the headlines - demanding new attention to how the life sciences industry will maintain cross-border product movement and manage regulatory administration from January 1. Updated guidelines for pharmaceuticals…
Challenging the problem of rising obesity levels, musculoskeletal injuries and liable in NHS mortuaries.
By Sharon Rindsland, Senior Manual Handling Co-ordinator, East Kent Hospitals Since 1975 worldwide obesity has nearly tripled. In 2016, more than 1.9 billion adults were classed as being overweight, of these 650 million were obese. However, this doesn’t just apply to adults, over 340 million children and adolescents aged 5-19 were overweight or obese in 2016 . Unfortunately, complications related to obesity continue post-mortem. Nursing staff and mortuary technicians often face these complications when processing and transferring overweight patients. Issues such as loss of dignity for the patient, difficulty transferring patients resulting in musculoskeletal injuries (MSI) for staff, inc…
Enzymes are a class of biological catalysts. They govern many catalytic processes such as metabolism, nutrition, and energy conversion of organisms. Most of the reactions closely related to life processes are enzyme-catalyzed reactions.
Catalysis Enzymes are a class of biological catalysts. They govern many catalytic processes such as metabolism, nutrition, and energy conversion of organisms. Most of the reactions closely related to life processes are enzyme-catalyzed reactions.   These properties of the enzyme enable the intricate process of material metabolism in the cell to proceed in an orderly manner, and to adapt material metabolism to normal physiological functions. If an enzyme is defective due to genetic defects, or the enzyme activity is weakened by other reasons, it can caus…
In order to carry out various life activities, the organism must obtain energy and produce new substances needed for its growth.
In order to carry out various life activities, the organism must obtain energy and produce new substances needed for its growth. By ingesting nutrients, organisms produce energy through decomposition; or produce new substances through synthesis. In organisms, nutrition molecules participate in various decomposition and synthesis reactions, collectively known as metabolism.   Any substance has more or less energy. When a substance changes through a chemical reaction, it will take a long time to complete under the condition of no external force. This long-term reaction is not enough to maintain life activity of the organism. Therefore, organisms have developed…
Enzymes are involved in the formation and composition of every cell in the body. Thus they also control the working of every organ and even the brain - the control center.
Enzymes are involved in the formation and composition of every cell in the body. Thus they also control the working of every organ and even the brain - the control center. They are involved in the breakdown, absorption, distribution and circulation of various nutrients entering the body. Overall, it would be sufficient to say that life would be non-existent without enzymes.   How many of us have ever been concerned about our gut health and how enzymes affect the digestive process. It obviously is the last thing that one would care about after a whole busy day and the same regular stressing lifestyle. People will not…
Enzymes work in a mild environment, similar to the physical environment of living organisms. Enzymes support life by synthesizing and degrading the materials that make up the components of the organism and creating energy.
Enzymes are molecules, especially proteins that help to accelerate biochemical reactions by interacting with components (reactants and products) without permanently changing them. This promotion process is called catalysis, and accordingly, the enzyme is recognized as a catalyst. Like many participants in the microbiology community, the names of enzymes can be lengthy and cumbersome, and almost all names end with "-ase". However, if you are familiar with the formal system of enzyme naming, you can unravel many mysteries about the function of a given enzyme without knowin…
Enzymes reduce the activation energy response that needs to occur, thus allowing our body to perform a series of reactions at low temperatures. Enzymes are the proteins that are needed in our system. Without them, we will not be able to survive.
Enzymes are vital to the human body. Without enzymes, cells in our body will not be able to carry out chemical reactions because the energy required is too grate. Enzymes reduce the activation energy response that needs to occur, thus allowing our body to perform a series of reactions at low temperatures. Enzymes are the proteins that are needed in our system. Without them, we will not be able to survive. The name of the enzyme depends on the action of the enzyme. Lipases break down fatty acids (lipids), and proteases break down proteins.   Se…
Along with the economic tide of global economic integration, the world biotechnology industry is also adjusting the industrial structure and product structure on a global scale, covering detergents, textiles, alcohol, spirits, beer, monosodium glutamate, organic acids, starch sugar, In the industrial fields of pharmaceutical, tanning, feed, paper, juice, meat, eggs, beans, milk, and pasta processing, the industrial added value has exceeded 100 billion dollars.
The industrial enzyme production industry has experienced rapid development for more than half a century, and has now formed a dynamic high-tech industry to maintain sustained high-speed development. In the past 10 years, some fundamental changes have taken place in production technology. With the continuous advancement and maturity…
Alzheimer's disease is one of the most common neurodegenerative disorder for the elderly. Early-onset Alzheimer's is rare that develops before age 65, primarily genetically influenced. Generally, the patients older than age 65 who account for a large proportion among the whole patients suffer from late-onset Alzheimer’s. The patients with late-onset Alzheimer’s have to fight against a series of frustrating symptoms, such as memory loss, poor language skills, unstable emotions, and no self-care ability, which may lead to numerous troubles or burden for themselves and the family members.
Alzheimer's disease is one of the most common neurodegenerative disorder for the elderly. Early-onset Alzheimer's is rare that develops before age 65, primarily genetically influenced. Generally, the patients…
Extensive research in the field of industrial enzymes has shown their use in various industries. Nowadays, many industries have begun to explore the superiorities of industrial enzymes in their production and processes, thus establishing a good market.
Enzymes can be utilized in numerous fields, such as enzymes for diagnostics and enzymes for cancer treatment. Due to the action of the enzyme, the chemical reaction in the organism can be effectively carried out under very mild conditions, enabling the organism to digest food, absorb nutrients, and maintain visceral functions such as anti-inflammatory detoxification, metabolism, immunity, energy production, blood promotion, circulation, etc. The body contains a variety of enzymes that control many metabolic processes such as metabolism, nutri…
A reasonable diet and adequate nutrition can improve the health of a generation, prevent a variety of diseases, prolong life and improve the physical fitness of the entire nation. Unreasonable diet, excessive or insufficient nutrition will bring different degrees of harm to health.
People get all the nutrients and energy they need through food. A reasonable diet and adequate nutrition can improve the health of a generation, prevent a variety of diseases, prolong life and improve the physical fitness of the entire nation. Unreasonable diet, excessive or insufficient nutrition will bring different degrees of harm to health. Overeating can lead to obesity, diabetes, cholelithiasis, hyperlipidemia, high blood pressure and other diseases due to overnutrition, and even induce mesothelioma, such…
Enzymes are nothing but the necessary proteins that maintain the various biological and chemical functions within the body and these include processes like digesting food to activating the brain and thousands of others. Enzymes act as a catalyst for millions of reactions that happen within the body, that make us grow, sleep, communicate, get hungry, feel and many more. Overall, it makes us live.
The growth and reproduction of life, birth and death, and metabolism are all related to enzymes. Without the catalysis of enzymes, humans can't even carry out the most basic life activities, such as food digestion, oxygen breathing, etc., let alone other problems. In fact, almost all kinds of reactions occurring in living organisms are carried out by enzyme catalysis. We can even say that the existe…
According to the different nutrient modes of microalgae, the culture modes can be divided into photoautotrophic culture, mixed culture and heterotrophic culture. And according to the different culture methods, the culture of microalgae can be divided into batch culture, fed-batch culture, semi-continuous culture and continuous culture. This article introduces the cultivation of microalgae.
m the physiological point of view, most microalgae should have the ability to grow heterotrophically. The growth process of microalgae using organic matter mainly has two forms: one is that microalgae can use organic matter to carry out heterotrophic growth under completely dark conditions, and there is no difference between the general chemical heterotrophic organisms; another form is that microalgae us…
The rapid rise of molecular enzymology and enzyme engineering has been promoted, making enzyme engineering an important role in bioengineering. In fact, it is an epoch-making leap in human understanding of enzymes, transformation of new enzymes and extensive use of enzymes.
With the great insights on enzyme catalytic mechanisms, biosynthesis, structure, and the rapid development of physical and chemical technology, the rapid rise of molecular enzymology and enzyme engineering has been promoted, making enzyme engineering an important role in bioengineering. In fact, it is an epoch-making leap in human understanding of enzymes, transformation of new enzymes and extensive use of enzymes.   The microbial enzyme source is the main source of enzyme engineering research. Biodiversit…
The severe side effects of conventional chemotherapeutic treatments can’t be ignored since in most cases, the valid drug dose that can remove the tumor are too toxic for patients. To solve the limitations, the antibody drug conjugates (ADCs) have emerged consisting of tumor-selective antibody-linked drugs, with the potential to significantly broaden the therapeutic range.
The severe side effects of conventional chemotherapeutic treatments can’t be ignored since in most cases, the valid drug dose that can remove the tumor are too toxic for patients. To solve the limitations, the antibody drug conjugates (ADCs) have emerged consisting of tumor-selective antibody-linked drugs, with the potential to significantly broaden the therapeutic range.   Antibody-drug conjugates (ADCs), the focus o…
Enzymes, in other words, are just proteins. Since there are only a lot of enzymes for industrial use in the future, it is known that the future development and optimization of catalytic proteins is essential. So what is enzymes development and optimization?
The interpretation of enzymes in the modern industry certainly does not refer to yeast, but to proteins with catalytic functions. As a natural catalyst, enzymes promote various chemical reactions in cells and play a vital role in the existence of living organisms. From the concept of enzymes, to the mature industrial enzyme production, it has probably gone through 130-40 years. The Greek translation of the enzyme is "in yeast", meaning from yeast. In 1897, after the methods of disruption for yeast, the extract obtained had the…
Compared to polyclonal antibodies, monoclonal antibodies have multiple advantages, featured by strong specificity for a single epitope, little or no variability, and the easy operation to modify and customize in terms of different needs, thereby turning out to be the most suitable candidate for recombinant antibodies (rAbs). The rAbs are obtained through sequencing of the animal's immune cells and inserting the gene into a suitable cell strain, such as bacterium, yeast, and mammalian cells. Even if the original cell strain dies or is mutated, the desired cell strain can be generated by gene insertion since the antibody is definitive.
In general, polyclonal antibodies are made by collecting blood from an immunized animal stimulated with a target antigen, which can be provided all the time as…
Bispecific antibody (BsAb) is an artificially engineered antibody that can simultaneously bind two specific epitopes or target proteins with some special biological functions, such as directly targeting effector cells to tumor cells, to enhance cytotoxicity, improve antibody selectivity and functionality, and avoid immune escape mechanisms, thereby improving therapeutic efficacy. BsAb also reduces the cost of drug development and clinical trials compared to the combination of two monoclonal antibody drugs.
Bispecific antibody (BsAb) is an artificially engineered antibody that can simultaneously bind two specific epitopes or target proteins with some special biological functions, such as directly targeting effector cells to tumor cells, to enhance cytotoxicity, improve antibody selectivity a…