Clinical research - Articles
The U.S. Food and Drug Administration recently granted marketing authorization for an anterior cruciate ligament (ACL) implant, intended to perform as an alternative to traditional ACL reconstructions. The Bridge-Enhanced ACL Repair (BEAR) Implant, by Miach Orthopaedics, differs from the traditional surgical reconstruction as it does not require the use of harvested tendons for ACL repair but rather helps the tendon to rebuild itself.
The U.S. Food and Drug Administration recently granted marketing authorization for an anterior cruciate ligament (ACL) implant, intended to perform as an alternative to traditional ACL reconstructions. The Bridge-Enhanced ACL Repair (BEAR) Implant, by Miach Orthopaedics, differs from the traditional surgical reconstruction as it does not require the use of har…
The U.S. Food and Drug Administration recently granted marketing authorization for an anterior cruciate ligament (ACL) implant, intended to perform as an alternative to traditional ACL reconstructions. The Bridge-Enhanced ACL Repair (BEAR) Implant, by Miach Orthopaedics, differs from the traditional surgical reconstruction as it does not require the use of har…
AI uses colorful, time-lapse heat maps to identify the features of embryos that could result in more successful implants and develop into a pregnancy.
Although in vitro fertilization solely involves a sperm and an egg, the process leading to an embryo can be more challenging than just putting the two together. In 2019, the Centers for Disease Control and Prevention (CDC) reported that approximately 10% of women in the U.S. between the ages of 15-44 had difficulty either getting pregnant or avoiding a miscarriage. This demographic of women suffering from ovulation disorders directly translates into a potential patient population for assisted reproduction procedures. According to one Israeli machine learning startup, AI has the potential to boost the success rate of in vitro fertilization (IV…
Although in vitro fertilization solely involves a sperm and an egg, the process leading to an embryo can be more challenging than just putting the two together. In 2019, the Centers for Disease Control and Prevention (CDC) reported that approximately 10% of women in the U.S. between the ages of 15-44 had difficulty either getting pregnant or avoiding a miscarriage. This demographic of women suffering from ovulation disorders directly translates into a potential patient population for assisted reproduction procedures. According to one Israeli machine learning startup, AI has the potential to boost the success rate of in vitro fertilization (IV…
05-Feb-2021
The duration and efficacy of the clinical trials for COVID-19 vaccine are the most considerable factors for the inventors. These two factors are focused based on statistical decisions. The statistical decisions are very helpful for the pharmaceuticals to get their roles quickly and more effectively. The following statistical areas played an important role in getting the COVID-19 vaccine trails quick and effective.
After all the tensions and confusion, mankind conquered COVID-19 disease through the development of effective vaccine. When you are going through the development history of vaccines, you will come across these terms; ITT Analysis, Toxicity Monitoring, Interim analysis, Immunogenicity, noninferiority, Vaccine efficacy, etc. Yes, these terms are relevant in a novel vaccine developme…
After all the tensions and confusion, mankind conquered COVID-19 disease through the development of effective vaccine. When you are going through the development history of vaccines, you will come across these terms; ITT Analysis, Toxicity Monitoring, Interim analysis, Immunogenicity, noninferiority, Vaccine efficacy, etc. Yes, these terms are relevant in a novel vaccine developme…
05-Feb-2021
Based on the type of study designs and manuscripts, there are different types of manuscript authoring guidelines such as CONsolidated Standards Of Reporting Trials (CONSORT) for randomized trials; STrengthening the Reporting of OBservational studies in Epidemiology (STROBE) for observational trials; CAse REport guidelines (CARE) for case reports; Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) for systematic reviews and meta-analyses; and STAndards for Reporting of Diagnostic accuracy studies (STARD) for diagnostic accurateness.
Medical Writers often seek information on global best practices that will enhance scientific manuscript writing skills while adhering to industry standards. Here we provide contemporary guidelines that should be followed while publishing…
Medical Writers often seek information on global best practices that will enhance scientific manuscript writing skills while adhering to industry standards. Here we provide contemporary guidelines that should be followed while publishing…
Pharmaceutical excipients can also be used in the manufacturing process, for example, by promoting the flowability or non-stick properties of the powder to assist in the handling of related active substances. In addition, they can also assist in vitro stability, such as preventing denaturation during the expected shelf life. The choice of suitable excipients also depends on the route of administration and dosage form, as well as the active ingredient and other factors.
Pharmaceutical excipients are natural or synthetic substances formulated together with the active ingredients of the drug, whose purpose is to increase the formulations containing effective active ingredients or endow the active ingredients in the final dosage form with therapeutic effects, such as promoting drug absorpt…
Pharmaceutical excipients are natural or synthetic substances formulated together with the active ingredients of the drug, whose purpose is to increase the formulations containing effective active ingredients or endow the active ingredients in the final dosage form with therapeutic effects, such as promoting drug absorpt…
Stryker has announced it has cleared all regulatory hurdles previously in the way of its planned $4.7 billion acquisition of Wright Medical. The tender offer was initiated back in November 2019 and has now been completed as of November 11, 2020.
Stryker has announced it has cleared all regulatory hurdles previously in the way of its planned $4.7 billion acquisition of Wright Medical. The tender offer was initiated back in November 2019 and has now been completed as of November 11, 2020. “Wright Medical has built a successful business, and together we look forward to working with customers to continue delivering solutions that improve patient outcomes,” Kevin Lobo, Chairman and Chief Executive Officer, Stryker Wright Medical was founded in 1950 in Memphis by an orthop…
Stryker has announced it has cleared all regulatory hurdles previously in the way of its planned $4.7 billion acquisition of Wright Medical. The tender offer was initiated back in November 2019 and has now been completed as of November 11, 2020. “Wright Medical has built a successful business, and together we look forward to working with customers to continue delivering solutions that improve patient outcomes,” Kevin Lobo, Chairman and Chief Executive Officer, Stryker Wright Medical was founded in 1950 in Memphis by an orthop…
Interventional cardiology is a minimally-invasive technique that uses catheters to treat coronary arterial disease, which is one of the leading causes of death in the United States. These procedures allow the heart to continue functioning at its best moving almost 3,000 gallons of blood every day. Based on the European Heart Journal, cardiovascular disease (CVD) causes more than four million deaths annually, accounting for nearly 45% of all deaths in Europe.
The COVID-19 outbreak caused massive procedural deferrals resulting in a spike of late-presenting STEMS and an increase in death rate in patients waiting for procedures Interventional cardiology is a minimally-invasive technique that uses catheters to treat coronary arterial disease, which is one of the leading causes of death in the…
The COVID-19 outbreak caused massive procedural deferrals resulting in a spike of late-presenting STEMS and an increase in death rate in patients waiting for procedures Interventional cardiology is a minimally-invasive technique that uses catheters to treat coronary arterial disease, which is one of the leading causes of death in the…
19-Mar-2021
While negotiations are still ongoing, the structure of the post-Brexit medicine testing and approval process is still unclear, and the UK government has so far ruled out an extension to the transition period which is due to come to an end at the end of this year.
While negotiations are still ongoing, the structure of the post-Brexit medicine testing and approval process is still unclear, and the UK government has so far ruled out an extension to the transition period which is due to come to an end at the end of this year. What is clear is that the Medicines and Healthcare products Regulatory Agency (MHRA) is becoming independent to the EMA’s drug approval and oversight process. It might result in the testing and release of products being completed under two separate regulatory frameworks. D…
While negotiations are still ongoing, the structure of the post-Brexit medicine testing and approval process is still unclear, and the UK government has so far ruled out an extension to the transition period which is due to come to an end at the end of this year. What is clear is that the Medicines and Healthcare products Regulatory Agency (MHRA) is becoming independent to the EMA’s drug approval and oversight process. It might result in the testing and release of products being completed under two separate regulatory frameworks. D…
There is a lot of research taking place in the pharmaceutical industry today. What are some of the biggest trends that everyone should note?
The worldwide pharmaceutical market has grown by leaps and bounds during the past few years. Given the massive impact that the COVID-19 pandemic has had on the world, the pharmaceutical industry is still looking for ways to provide helpful products to those who need them most. The good part about this industry is that they are quick to pump new funds back into their own research in an effort to continue to help others. With this in mind, there are a few major trends that are dominating the landscape of the pharmaceutical industry and they will play a role in the development of this field in the years to come. The Growth of AI Tech for Resea…
The worldwide pharmaceutical market has grown by leaps and bounds during the past few years. Given the massive impact that the COVID-19 pandemic has had on the world, the pharmaceutical industry is still looking for ways to provide helpful products to those who need them most. The good part about this industry is that they are quick to pump new funds back into their own research in an effort to continue to help others. With this in mind, there are a few major trends that are dominating the landscape of the pharmaceutical industry and they will play a role in the development of this field in the years to come. The Growth of AI Tech for Resea…
Cancer research has come a long way during the past several years. What does the future of cancer treatment look like?
The past few years have been an exciting time in the field of cancer research as some of the top minds in the world try to find ways to fight a disease that is only becoming more common. There are a few top cancer research findings that have risen to the surface. 1. Cancer Energy Source First, researchers found that cancer cells need an unlimited supply of energy and this usually comes in the form of glucose. A research team found that leukemia cells, a type of blood cancer, will undercut the ability of normal cells to consume glucose. They were able to steal glucose from healthy cells, fueling the growth and spread of cancer throughout the body. Furthermore, the r…
The past few years have been an exciting time in the field of cancer research as some of the top minds in the world try to find ways to fight a disease that is only becoming more common. There are a few top cancer research findings that have risen to the surface. 1. Cancer Energy Source First, researchers found that cancer cells need an unlimited supply of energy and this usually comes in the form of glucose. A research team found that leukemia cells, a type of blood cancer, will undercut the ability of normal cells to consume glucose. They were able to steal glucose from healthy cells, fueling the growth and spread of cancer throughout the body. Furthermore, the r…
Within this article, the use of coagulation testing is discussed in assessing the potential outcomes for COVID positive cases.
With the level of incidence of thrombosis in patients admitted to hospital in severe condition due to the disease, coagulation tests such as D-dimer, prothrombin time (PT) and activated partial thromboplastin time (aPTT) have become important indicators for hospitals. A study published by a French group in May 2020 in Intensive Care Medicine (1) shows an increase in the occurrence of prothrombotic events, especially pulmonary thromboembolisms, in patients with severe clinical symptoms of Covid-19 infection. Given the urgency of the current situation caused by the new coronavirus (Sars-CoV-2) pandemic, studies on this topic have been intensified worldwide at a rec…
With the level of incidence of thrombosis in patients admitted to hospital in severe condition due to the disease, coagulation tests such as D-dimer, prothrombin time (PT) and activated partial thromboplastin time (aPTT) have become important indicators for hospitals. A study published by a French group in May 2020 in Intensive Care Medicine (1) shows an increase in the occurrence of prothrombotic events, especially pulmonary thromboembolisms, in patients with severe clinical symptoms of Covid-19 infection. Given the urgency of the current situation caused by the new coronavirus (Sars-CoV-2) pandemic, studies on this topic have been intensified worldwide at a rec…
On behalf of the organizing committee; we invite you to join us for an exciting and stimulating meeting! The principal objective of this conference is to provide an international forum for cutting edge research in Nursing, Nursing Education and Research. A high-quality scientific program is planned, which will strike a balance between various sub-specialties in Nursing.
We are looking for Speakers and Delegates who are interested to participate at our upcoming 29th Edition of World Congress on Nursing Education & Research during May 25-26, 2020 Dublin, Ireland. Nursing Education-2020 aims to discover advances in health practice, management and education with the leading world doctors, registered nurses, health care professionals, professors, research fellows, universities, students, dir…
We are looking for Speakers and Delegates who are interested to participate at our upcoming 29th Edition of World Congress on Nursing Education & Research during May 25-26, 2020 Dublin, Ireland. Nursing Education-2020 aims to discover advances in health practice, management and education with the leading world doctors, registered nurses, health care professionals, professors, research fellows, universities, students, dir…
The UK Government is at risk of missing its target to increase healthy life expectancy by five years by 2035, according to a new report, Growing Older, Better, published by The Physiological Society on Tuesday 15 October.
Healthy life expectancy, which is the number of years lived in good health, has not increased as quickly as life expectancy in recent decades, which means people are living more years in poor health. The UK Government’s Industrial Strategy contains a target of “ensur[ing] that people can enjoy at least five extra healthy, independent years of life by 2035, while narrowing the gap between the experience of the richest and poorest”. This new report, which is the result of a project involving an expert panel of researchers, funders and public health policy makers, outlines co…
Healthy life expectancy, which is the number of years lived in good health, has not increased as quickly as life expectancy in recent decades, which means people are living more years in poor health. The UK Government’s Industrial Strategy contains a target of “ensur[ing] that people can enjoy at least five extra healthy, independent years of life by 2035, while narrowing the gap between the experience of the richest and poorest”. This new report, which is the result of a project involving an expert panel of researchers, funders and public health policy makers, outlines co…
Resistance to anticancer drugs results from a variety of factors, and individual genetic difference is just one of them. This article is about how to overcome drug resistance against KRAS inhibitors in cancer treatment.
Recently, KRAS and KRAS-G12C mutant inhibitors, which were previously considered to be "non-drugable" targets, have ignited a development boom. However, KRAS inhibitors are not a "magic bullet" for once and for all. Drug resistance is a major problem that frequently occurs in cancer treatment. In clinical practice, tumor tissue becomes significantly smaller after targeted therapy, but soon deteriorates again. Such scenes are commonly observed in real situations. Amgen's latest clinical trial results also indicate that some patients treated with the KRAS-G12C inhibitor AMG 51…
Recently, KRAS and KRAS-G12C mutant inhibitors, which were previously considered to be "non-drugable" targets, have ignited a development boom. However, KRAS inhibitors are not a "magic bullet" for once and for all. Drug resistance is a major problem that frequently occurs in cancer treatment. In clinical practice, tumor tissue becomes significantly smaller after targeted therapy, but soon deteriorates again. Such scenes are commonly observed in real situations. Amgen's latest clinical trial results also indicate that some patients treated with the KRAS-G12C inhibitor AMG 51…
08-Oct-2019
Here are the top Pharma and Life Science recruitment organisations advertising in September on PharmiWeb.jobs.
Barrington James Clinical - 206 Jobs RBW Consulting - 163 Jobs i-Pharm Consulting - 141 Jobs CHASE - 133 Jobs SEC Recruitment - 116 Jobs ID Search & Selection - 86 Jobs Clinical Professionals Ltd - 85 Jobs Hobson Prior - 76 Jobs CK Clinical - 68 Jobs Barrington James Europe - 63 Jobs X4 Life Sciences - 63 Jobs Advanced Regulatory (UK & Europe) - 60 Jobs Barrington James Medical / Executive - 58 Jobs Thornshaw Recruitment - 56 Jobs Barrington James Scientific - 48 Jobs Only Medics Recruitment ltd - 46 Jobs Planet Pharma Staffing Limited - 45 Jobs Umbilical Life - 44 Jobs ProClinical Ltd - 39 Jobs CTC Resourcing Solutions - 34 Jobs Volt - 31 Jobs Haybury - 31 Jobs Advanced S…
Barrington James Clinical - 206 Jobs RBW Consulting - 163 Jobs i-Pharm Consulting - 141 Jobs CHASE - 133 Jobs SEC Recruitment - 116 Jobs ID Search & Selection - 86 Jobs Clinical Professionals Ltd - 85 Jobs Hobson Prior - 76 Jobs CK Clinical - 68 Jobs Barrington James Europe - 63 Jobs X4 Life Sciences - 63 Jobs Advanced Regulatory (UK & Europe) - 60 Jobs Barrington James Medical / Executive - 58 Jobs Thornshaw Recruitment - 56 Jobs Barrington James Scientific - 48 Jobs Only Medics Recruitment ltd - 46 Jobs Planet Pharma Staffing Limited - 45 Jobs Umbilical Life - 44 Jobs ProClinical Ltd - 39 Jobs CTC Resourcing Solutions - 34 Jobs Volt - 31 Jobs Haybury - 31 Jobs Advanced S…
08-Oct-2019
A list of the TOP Pharma Companies who are hiring this month (September)
Covance - 388 Jobs BSI Group - 167 Jobs PRA Health Sciences - 105 Jobs PPD- 81 Jobs Roche - 77 Jobs Synteract- 74 Jobs United BioSource Corporation. - 69 Jobs Cytel - 68 Jobs Syneos Health - 52 Jobs CROMSOURCE - 51 Jobs IQVIA - 36 Jobs AstraZeneca - 36 Jobs Celgene - 32 Jobs IQVIA Biotech - 21 Jobs Oxford BioMedica (UK) Limited - 16 Jobs Lonza - 16 Jobs Grunenthal GmbH - 14 Jobs Register and Upload Your CV Now
Covance - 388 Jobs BSI Group - 167 Jobs PRA Health Sciences - 105 Jobs PPD- 81 Jobs Roche - 77 Jobs Synteract- 74 Jobs United BioSource Corporation. - 69 Jobs Cytel - 68 Jobs Syneos Health - 52 Jobs CROMSOURCE - 51 Jobs IQVIA - 36 Jobs AstraZeneca - 36 Jobs Celgene - 32 Jobs IQVIA Biotech - 21 Jobs Oxford BioMedica (UK) Limited - 16 Jobs Lonza - 16 Jobs Grunenthal GmbH - 14 Jobs Register and Upload Your CV Now
30-Jul-2019
Hepatitis E is a liver disease caused by infection due to a virus known as hepatitis E virus (HEV). This disease can cause swelling in liver. Some of the common symptoms are mild fever, feeling of tiredness, feeling sick to stomach, and belly pain.
Hepatitis E is a liver disease caused by infection due to a virus known as hepatitis E virus (HEV). This disease can cause swelling in liver. Some of the common symptoms are mild fever, feeling of tiredness, feeling sick to stomach, and belly pain. Download the sample report at: https://www.pharmaproff.com/request-sample/1029 The World Health Organization (WHO) estimates released in 2018 stated that, every year, an estimated 20 million HEV infections worldwide, leading to an estimated 3.3 million symptomatic cases of hepatitis E. Although, this d…
Hepatitis E is a liver disease caused by infection due to a virus known as hepatitis E virus (HEV). This disease can cause swelling in liver. Some of the common symptoms are mild fever, feeling of tiredness, feeling sick to stomach, and belly pain. Download the sample report at: https://www.pharmaproff.com/request-sample/1029 The World Health Organization (WHO) estimates released in 2018 stated that, every year, an estimated 20 million HEV infections worldwide, leading to an estimated 3.3 million symptomatic cases of hepatitis E. Although, this d…
From driverless cars being rolled out recently to robots performing surgeries, technology has surely made a stellar progress. One such example is medical robots. Medical robots are set to revolutionize the healthcare sector, especially surgeries, since they are becoming more and more acceptable, globally. They not only help in reducing the time of surgery but also ensure the accuracy of the whole process coupled with better quality of patient care, thereby increasing the demand for surgical robots across the globe.
The growth of the Medical Robots Market can be attributed to the issuance of IPOs by medical robot companies, advantages offered by robot-assisted training in rehabilitation therapy, growing hospital investments in medical robots, increasing funding for medical robot research, an…
The growth of the Medical Robots Market can be attributed to the issuance of IPOs by medical robot companies, advantages offered by robot-assisted training in rehabilitation therapy, growing hospital investments in medical robots, increasing funding for medical robot research, an…
Many of us don’t like to think about death, in fact, we avoid the subject where possible. Banishing the taboo around death is important, as, after all, we are all going to die someday, so why aren’t we more open about discussing it?
Many of us don’t like to think about death, in fact, we avoid the subject where possible. Banishing the taboo around death is important, as, after all, we are all going to die someday, so why aren’t we more open about discussing it? The more we talk about death, the easier it will be to normalise the subject and feel less fearful of the unknown. Whether you want to talk about it or not, one aspect of death that you can’t hide from is deciding what you want to happen to your body when you pass. It’s not a particularly pleasant thought but it is one you’ll eventua…
Many of us don’t like to think about death, in fact, we avoid the subject where possible. Banishing the taboo around death is important, as, after all, we are all going to die someday, so why aren’t we more open about discussing it? The more we talk about death, the easier it will be to normalise the subject and feel less fearful of the unknown. Whether you want to talk about it or not, one aspect of death that you can’t hide from is deciding what you want to happen to your body when you pass. It’s not a particularly pleasant thought but it is one you’ll eventua…
On 30 March, at the fourth annual Talking About Diabetes event, a host of celebrities, athletes, patients and healthcare professionals took to the stage to share their inspirational stories of living with and managing type 1 diabetes.
On 30 March, at the fourth annual Talking About Diabetes event, a host of celebrities, athletes, patients and healthcare professionals took to the stage to share their inspirational stories of living with and managing type 1 diabetes. Through a series of talks, the speakers provided fresh perspectives on living with type 1 diabetes, whilst experts in the area provided insights on the importance of removing barriers and embracing new technologies. Novo Nordisk UK is a key sponsor of the event, which took place at the Royal College of Physicians, London. Actor…
On 30 March, at the fourth annual Talking About Diabetes event, a host of celebrities, athletes, patients and healthcare professionals took to the stage to share their inspirational stories of living with and managing type 1 diabetes. Through a series of talks, the speakers provided fresh perspectives on living with type 1 diabetes, whilst experts in the area provided insights on the importance of removing barriers and embracing new technologies. Novo Nordisk UK is a key sponsor of the event, which took place at the Royal College of Physicians, London. Actor…
