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Between 2017-2018, NHS England spent £173m on blood glucose (SMBG) test strips alone to care for diabetes patients. With an increasing number of people diagnosed with type 2 diabetes, there is a clear need to cost save by rationalising the number of SMBG systems in use. By encouraging CCGs and prescribers to consider more cost-effect alternatives and identifying opportunities for efficiency savings, while retaining high standards of accuracy, now is the time to recognise and adopt best practice in formulary implementation David Englefield, Spirit Healthcare outlines how CCGs can change how they manage and implement their formulary in the below article.
Reducing the cost of SMBG test strips  With the latest news from NHS England highlighting that £700 million cost savings have…
A complex problem requires a sophisticated resolution. The good news is that the technology is out there to help manufacturers tackle these challenges posed by counterfeiters. In the article, Bart Vansteenkiste, Global Life Science Sector Development Manager at Domino Printing Sciences plc, explains the different areas of packaging that are under threat by counterfeiters and how to avoid them.
Underground criminals producing counterfeit goods have become alarmingly good at replicating manufacturers’ branding and are infiltrating the market. That’s a significant problem for both manufacturers and consumers, and the scale of the issue is rising. Counterfeit products can present terrifying dangers. These falsified products are then made to look authentic thanks to replicated labelling that app…
If you’re upgrading or implementing a new hospital reporting system, what key questions do you need to ask to ensure that the technology provides you with the data set you need to ensure your organisation is safe operationally
DR MARK RATNARAJAHManaging Director (UK), C2-Ai - providing unique risk-adjusted systems for individualised patient risk prediction, avoiding harm and mortality in hospitals. In August this year, the Prime Minister pledged £250m to boost artificial intelligence and genomic testing in the NHS citing, amongst others, the benefits of harnessing NHS data. The long-term vision is to help the NHS become a world leader in utilising innovation and technology.At the time, Health Secretary Matt Hancock commented; “We are on the cusp of a huge health tech revolution that co…
Enzymes are nothing but the necessary proteins that maintain the various biological and chemical functions within the body and these include processes like digesting food to activating the brain and thousands of others. Enzymes act as a catalyst for millions of reactions that happen within the body, that make us grow, sleep, communicate, get hungry, feel and many more. Overall, it makes us live.
The growth and reproduction of life, birth and death, and metabolism are all related to enzymes. Without the catalysis of enzymes, humans can't even carry out the most basic life activities, such as food digestion, oxygen breathing, etc., let alone other problems. In fact, almost all kinds of reactions occurring in living organisms are carried out by enzyme catalysis. We can even say that the existe…
According to the different nutrient modes of microalgae, the culture modes can be divided into photoautotrophic culture, mixed culture and heterotrophic culture. And according to the different culture methods, the culture of microalgae can be divided into batch culture, fed-batch culture, semi-continuous culture and continuous culture. This article introduces the cultivation of microalgae.
m the physiological point of view, most microalgae should have the ability to grow heterotrophically. The growth process of microalgae using organic matter mainly has two forms: one is that microalgae can use organic matter to carry out heterotrophic growth under completely dark conditions, and there is no difference between the general chemical heterotrophic organisms; another form is that microalgae us…
As more routine PV work is automated, and as technology literacy moves up the qualifications & experience wish list, a serious review of resourcing and education strategies is needed. That’s if the life sciences industry is going to have fit-for-purpose PV teams in future.
As more routine PV work is automated, and as technology literacy moves up the qualifications & experience wish list, a serious review of resourcing and education strategies is needed. That’s if the life sciences industry is going to have fit-for-purpose PV teams in future. Drawing on her many years in pharma operations management, Anna Lukyanova, COO of Arriello, assesses the growing talent gap and suggests how the industry might address it. It seems remarkable that the people currently assuming pharmacovigilance rol…
The rapid rise of molecular enzymology and enzyme engineering has been promoted, making enzyme engineering an important role in bioengineering. In fact, it is an epoch-making leap in human understanding of enzymes, transformation of new enzymes and extensive use of enzymes.
With the great insights on enzyme catalytic mechanisms, biosynthesis, structure, and the rapid development of physical and chemical technology, the rapid rise of molecular enzymology and enzyme engineering has been promoted, making enzyme engineering an important role in bioengineering. In fact, it is an epoch-making leap in human understanding of enzymes, transformation of new enzymes and extensive use of enzymes.   The microbial enzyme source is the main source of enzyme engineering research. Biodiversit…
Mojgan Sani has recently taken over the role of Chief Pharmacist at North Tees and Hartlepool NHS Foundation Trust. Here she talks about how the automation of medication management can help meet many of the challenges currently facing the NHS.
Accessibility to social care isn’t the only issue causing bed blocking across the NHS – pharmacy have a crucial role to play in freeing up bed space too. As a profession, we need to look at streamlining the process for To Take Out (TTO) medication and how automation can achieve this.  The latest annual inpatient survey by the Care Quality Commission found 73% of patients “whose discharge had been delayed” said the main reason was “that they had to wait for medicines”.  Of the 76,668 patients who responded more than a quarter said they had wa…
Resistance to anticancer drugs results from a variety of factors, and individual genetic difference is just one of them. This article is about how to overcome drug resistance against KRAS inhibitors in cancer treatment.
Recently, KRAS and KRAS-G12C mutant inhibitors, which were previously considered to be "non-drugable" targets, have ignited a development boom. However, KRAS inhibitors are not a "magic bullet" for once and for all. Drug resistance is a major problem that frequently occurs in cancer treatment. In clinical practice, tumor tissue becomes significantly smaller after targeted therapy, but soon deteriorates again. Such scenes are commonly observed in real situations. Amgen's latest clinical trial results also indicate that some patients treated with the KRAS-G12C inhibitor AMG 51…
The severe side effects of conventional chemotherapeutic treatments can’t be ignored since in most cases, the valid drug dose that can remove the tumor are too toxic for patients. To solve the limitations, the antibody drug conjugates (ADCs) have emerged consisting of tumor-selective antibody-linked drugs, with the potential to significantly broaden the therapeutic range.
The severe side effects of conventional chemotherapeutic treatments can’t be ignored since in most cases, the valid drug dose that can remove the tumor are too toxic for patients. To solve the limitations, the antibody drug conjugates (ADCs) have emerged consisting of tumor-selective antibody-linked drugs, with the potential to significantly broaden the therapeutic range.   Antibody-drug conjugates (ADCs), the focus o…
Dr. Dennise Broderick, President and Managing Director of global speciality pharmaceutical company, Galen, was the first member to participate in Northern Ireland Chamber of Commerce and Industry’s CEO Spotlight Series.
Craigavon, N.I., 7 Oct 2019 - Dr. Dennise Broderick, President and Managing Director of global speciality pharmaceutical company, Galen, was the first member to participate in Northern Ireland Chamber of Commerce and Industry’s CEO Spotlight Series. Supported by KPMG, the series, which was formally launched on Thursday 3rd October, aims to inspire business growth in local companies through exchanging leadership stories of successful entrepreneurs and senior managers. The inaugural event took place at KPMG’s Soloist Building in Belfast and consisted of a business breakfast fe…
Enzymes, in other words, are just proteins. Since there are only a lot of enzymes for industrial use in the future, it is known that the future development and optimization of catalytic proteins is essential. So what is enzymes development and optimization?
The interpretation of enzymes in the modern industry certainly does not refer to yeast, but to proteins with catalytic functions. As a natural catalyst, enzymes promote various chemical reactions in cells and play a vital role in the existence of living organisms. From the concept of enzymes, to the mature industrial enzyme production, it has probably gone through 130-40 years. The Greek translation of the enzyme is "in yeast", meaning from yeast. In 1897, after the methods of disruption for yeast, the extract obtained had the…