Biotech - Articles

Pharmaceutical analysis mainly uses chemical, physical-chemical, or biochemical methods and techniques to study chemical structures that have been clarified.
Pharmaceutical analysis is the application of analytical chemistry in pharmacy. It is a "method science" for the research and development of drug quality control. It mainly uses chemical, physical-chemical, or biochemical methods and techniques to study chemical structures that have been clarified. UV-Vis Absorption Detector Ultraviolet-visible detector (UVD) is one of the most widely used detectors in HPLC, and almost all liquid chromatographs are equipped with this detector. UVD is characterized by high sensitivity, wide linear range, low noise, and is suitable for gradient elution. The detection limit for strongly absorbing sub…

This article highlights how AI and automation are driving innovation in clinical trial research by improving patient outcomes, reducing costs, and overcoming traditional barriers to progress.
AI (Artificial Intelligence) and automation are increasingly being used in various industries, including the pharmaceutical and biotech industries, to improve efficiency, and accuracy, and speed up the drug development process. AI and automation in clinical trials can play a significant role in streamlining the process, reducing costs, and improving patient outcomes. Here are some ways AI and automation are being used in clinical trials: Patient recruitment:  AI-powered tools can be used to analyze patient data and identify individuals who meet the criteria for a particular clinical trial. This c…

Proteins are among the most vital molecules in living organisms, playing crucial roles in cell function, signal transduction, and drug development, to name just a few. However, directly observing and studying the three-dimensional structures of proteins is not an easy task. Fortunately, the development of protein structure modeling technology has provided us with a powerful tool to unravel the mysteries of proteins and has significantly contributed to drug design and life sciences research.
Proteins are among the most vital molecules in living organisms, playing crucial roles in cell function, signal transduction, and drug development, to name just a few. However, directly observing and studying the three-dimensional structures of proteins is not an easy task. Fortunately, the developme…

In the fast-paced realm of drug discovery, scientists constantly seek innovative approaches to efficiently and cost-effectively identify potential drug candidates. Virtual screening, a breakthrough computational technique, is poised to transform the pharmaceutical industry. In this article, we delve into the world of virtual screening and explore its remarkable potential to revolutionize drug discovery.
In the fast-paced realm of drug discovery, scientists constantly seek innovative approaches to efficiently and cost-effectively identify potential drug candidates. Virtual screening, a breakthrough computational technique, is poised to transform the pharmaceutical industry. In this article, we delve into the world of virtual screening and explore its remarkable potential to revolutionize dru…

Explore the importance of cytokines in cutting-edge biomedical research, from organoid culture to stem cell therapy. Learn how to select high-quality cytokines with Beta LifeScience, your trusted supplier for low-endotoxin cytokines.
Low Endotoxin Cytokines Matters Organoid culture, CAR-T cell therapy, stem cell therapy, and other topics have become broadly discussed among biomedical researchers. In fact, it is not difficult to see that these advanced technologies are all related to cell culture. In order to maintain efficient growth, proliferation, and differentiation during in vitro cell culture, many cell cultures require the addition of various cytokines. Cytokines Backgrounds Cytokines are proteins synthesized and secreted by immune cells such as monocytes/macrophages and certain non-i…

Welcome to an in-depth exploration of trypsin, an extraordinary enzyme that has revolutionized the field of biotechnology. In this comprehensive article, we will uncover the underlying mechanisms, diverse functions, and cutting-edge uses of trypsin, highlighting its pivotal role in driving advancements in biotechnological research and industrial processes.
Introduction Welcome to an in-depth exploration of trypsin, an extraordinary enzyme that has revolutionized the field of biotechnology. In this comprehensive article, we will uncover the underlying mechanisms, diverse functions, and cutting-edge uses of trypsin, highlighting its pivotal role in driving advancements in biotechnological research and industrial processes.   What is Trypsin? Trypsin is a serine protease that naturally oc…

In contemporary life science research, enzymes play indispensable roles in numerous vital processes. Among them, Oxidoreductases are a crucial class of enzymes. By catalyzing oxidation-reduction reactions, Oxidoreductases participate in essential biological processes such as energy metabolism, cellular signal transduction, and various metabolic pathways. This article aims to explore the mysteries of Oxidoreductases and introduce Creative Enzymes’ cutting-edge technologies and applications in this field.
Introduction In contemporary life science research, enzymes play indispensable roles in numerous vital processes. Among them, Oxidoreductases are a crucial class of enzymes. By catalyzing oxidation-reduction reactions, Oxidoreductases participate in essential biological processes such as ene…

Automata launches LINQ Cloud: cutting-edge laboratory automation software that connects a lab’s physical and digital environment.
Automata, a leading company powering life science labs to fully automate their workflows, today launches LINQ Cloud: cutting-edge laboratory automation software. LINQ Cloud connects a lab’s physical and digital environment together, enabling life science organisations to scale while reducing the manual workload for scientists. LINQ Cloud works alongside Automata’s new LINQ automated lab bench, to create a lab automation solution specific to every lab’s workflow that enables true walkaway time. This means labs can reduce the manual workload for scientists – so they can spend more time on meaningful science. The software features an easy-to-use, intuitive interface…

The European Commission's revision of its Good Manufacturing Practices (GMP) Annex 1 for sterile drug products will be implemented soon, meaning pharmaceutical professionals need to understand the implications and put any additional measures in place – but what are the changes and what impact will they have on the industry?
The European Commission's revision of its Good Manufacturing Practices (GMP) Annex 1 for sterile drug products was released in August 2022, after 14 years of development. The proposed changes will be implemented one year on from publication, or two years for section 8.123 on lyophilizer sterilisation, giving pharmaceutical professionals time to understand the implications and put any additional measures in place – but what are the changes and what impact will they have o…

Generic drugs are incredibly important in the medical field, not only for their effectiveness but also for their cost-saving potential for both manufacturers and customers.
Generic drugs are incredibly important in the medical field, not only for their effectiveness, but also for their cost-saving potential for both manufacturers and customers.   Medication affordability is a prevalent issue, according to a study from West Health and Gallup, an estimated 15.5 million adults under 65 went without medication due to high drug costs. As such, it is vital that the development of generic medicines is as efficient as possible as they are much more accessible to all budgets in comparison to their branded counterparts. Bachem, a Swiss pharmaceutical company, is leading the way with a multidis…

Microorganisms can be found everywhere, in the coldest or hottest environment, in the air, in water, in soil, in plants, and even inside the human body. These organisms have a big contribution to the ecosystem and to the biosphere as a whole. They have existed even before the earth was habitable for other organisms such as plants and animals. In fact, studies have shown that all organisms have evolved from a single prokaryote or more commonly known as the Last Universal Common Ancestor (LUCA). Today, it has been estimated that there are about one trillion species of microorganisms in the world and 99.999 percent are not yet known and still need to be classified.
Microorganisms can be found everywhere, in the coldest or hottest environment, in the air, in water, in soil, in plants, and even…

High performance liquid chromatography (HPLC) has become an essential technique in pharmaceutical analysis for the separation, identification, and quantification of pharmaceuticals.
High performance liquid chromatography (HPLC) has become an essential technique in pharmaceutical analysis for the separation, identification, and quantification of pharmaceuticals. Due to its high resolution and sensitivity, it is used for testing drug purity, monitoring degradation, studying pharmacokinetics, and examining drug stability. With recent advances in instrumentation, the technique has become more efficient in terms of separating multiple components and analyzing tricky chemical compounds. The use of HPLC in pharmaceutical analysis has improved drug safety and efficacy, providing…

Tn5 transposase, as an enzyme has been broadly applied to the field of biotech, really needs to be accompanied by a brief introduction/protocol on its construction, preparation, and application to optimize the consequence brought by its participation.
      As an enzyme that has several applications in the field of biotech, Tn5 transposase, a bacterial transposase working in a “cut-and- paste” mode with amplification, can insert specific DNA sequences into a variety of substrates, including plasmids, bacterial chromosomes, and artificial DNA constructs. The following content will introduce the usage method of Tn5 transposase and the application of Tn5 transposase into genomic research and pharmaceuticals.        To get ready for any further application, T…

Semiconductor materials are a class of electronic materials that have semiconductor properties and are used to make semiconductor devices.
Semiconductor materials are a class of electronic materials that have semiconductor properties and are used to make semiconductor devices. Characteristics of semiconductor materials Semiconductor materials usually have a certain forbidden band width and their electrical properties are susceptible to external conditions (e.g., light, temperature, etc.). Different conductive types of materials are prepared by doping with specific impurities. Impurities (especially heavy metal fast diffusion impurities and deep energy level impurities) have a particularly strong influence on the material properties. Therefore, semiconductor materials should be of high…

The basic principle of organic photovoltaic cells is similar to inorganic solar cells. According to mechanical properties and processability, organic photovoltaic cell materials can be divided into insoluble materials, soluble materials, and liquid crystal materials.
History of organic photovoltaic cells Photovoltaic effect refers to the phenomenon in which a potential difference is generated between different regions of a semiconductor or a combination of semiconductors and metals that are illuminated by light. The term "photo-voltaic" appeared in English in 1849, which means that electromotive force is generated by light, that is, light generates volts. With the gradual understanding of the physical properties of semiconductors and the advancement of processing technology, in 1954, resear…

Consistent and reliable ‘in-flight’ data, flowing between different functions and software solutions, is key to driving business process efficiency in pharma companies. Max Kelleher, Chief Operating Officer at Generis and Remco Munnik, a Director at Iperion, a Deloitte business, explain how to maximise this opportunity.
Leveraging live company master data more effectively and strategically, thereby creating a flow of broader data and insights between functions, will enhance a range of different use cases. Much of this ‘in-flight’ data is incidental information captured as part of a task, yet its value in providing oversight, traceability and impact assessment to senior management could be considerable – if only companies could find a way to harness and control it more systematically. The ha…

Exosomes are extracellular vesicles (EVs) with a diameter of 30-140 nm. They are carriers of functional substances such as proteins, non-coding RNA, mRNA, and lipids. They act as messengers in cells, and It has the function of changing the biological activity of recipient cells. In 1980, exosomes were defined by Johnstone et al. As small vesicles that retain similar enzymatic activity as the parental cells. They undergo budding and formation of multiple vesicles (MVBs), and merge with the plasma membrane (PM), and eventually released outside the cell, at the same time, the exosome can also be internalized by endocytosis within the cell, and its contents are delivered to the target cell, thereby changing the biological function of the cell.
Exosomes are extracellular vesicles (EVs) with a di…

The discovery of antibody drugs is a rapidly developing field, and antibody modeling services offer reliable and efficient tools for their discovery and design. By predicting the interactions between antibody drugs and molecular targets, antibody modeling services can enhance the affinity and specificity of antibody drugs and reduce the development time and cost.
The discovery of antibody drugs is a rapidly developing field, and antibody modeling services offer reliable and efficient tools for their discovery and design. By predicting the interactions between antibody drugs and molecular targets, antibody modeling services can enhance the affinity and specificity of antibody drugs and reduce the development time and cost.   In addition to antibody modeling services, there are other com…

Protein-DNA docking is a complex and critical technique used in the field of structural biology. It involves the study of the three-dimensional structure of biological macromolecules, which play vital roles in many biological processes such as transcription, replication, and DNA repair. Protein-DNA docking allows researchers to predict how proteins and DNA interact with each other, providing crucial insights into the mechanisms that govern biological processes.
Protein-DNA docking is a complex and critical technique used in the field of structural biology. It involves the study of the three-dimensional structure of biological macromolecules, which play vital roles in many biological processes such as transcription, replication, and DNA repair. Protein-DNA docking allows researchers to predi…

Enzymes are biological catalysts that facilitate chemical reactions by lowering the activation energy required for the reaction to occur. They are typically composed of proteins and exhibit high specificity for the chemical reactions they catalyze. Enzymes have numerous applications in industry, including pharmaceuticals, food, and biotechnology. However, enzymes can also be used in households to solve everyday problems.
Enzymes are biological catalysts that facilitate chemical reactions by lowering the activation energy required for the reaction to occur. They are typically composed of proteins and exhibit high specificity for the chemical reactions they catalyze. Enzymes have numerous applications in industry, including pharmaceuticals, food, and biotechnology. However, enzymes can also b…