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Cytokines are small soluble proteins that are secreted by immune cells and tissue cells to play a regulatory role between cells, including interferon (IFN), interleukin (IL), chemokines, colony-stimulating factors (CSF), tumor necrosis factors (TNF) and so on. Cytokines function in autocrine, paracrine or endocrine forms, and can regulate cell growth and differentiation, modulate immune response and participate in the development of various diseases such as inflammation by binding to the corresponding receptors.
Cytokines are small soluble proteins that are secreted by immune cells and tissue cells to play a regulatory role between cells, including interferon (IFN), interleukin (IL), chemokines, colony-stimulating factors (CSF), tumor necrosis factors (TNF) and so on. Cytokines function in…
Lipidomics, a platform developed by Creative Proteomics, is dedicated to providing cutting-edge mass spectrometry (MS)-based lipidomics services for biomedical research institutions, and biotechnological and pharmaceutical companies. Creative Proteomics Lipidomics launched the steroid analysis service capable of quantifying up to 38 steroids in biological matrices such as plasma, serum, tissue, cells, and cell culture media.
Lipidomics, a platform developed by Creative Proteomics, is dedicated to providing cutting-edge mass spectrometry (MS)-based lipidomics services for biomedical research institutions, and biotechnological and pharmaceutical companies. Creative Proteomics Lipidomics launched the steroid analysis service capable of quantifying up to 38 steroids in biological matrices such…
the demand for inulin increased at a CAGR of about 6% between 2016 and 2020. Growth was mostly supported by their proven advantages for preserving digestion and intestinal health. In addition, inulin helps individuals with type 2 diabetes improve their lipid profiles and control their glycemic status
Inulin  Market : Introduction Wheat, onions, bananas, leeks, artichokes, and asparagus are just a few examples of the many fruits, vegetables, and herbs that contain inulin. Inulin is a substance found frequently in plants, and some makers add it to processed meals. Another polymer of the fructose molecule is inulin (fructan). It is prebiotic, which means that it feeds the beneficial bacteria in the gut, like other fructans do. Additionally, inulin and other prebiotics are converted by gut…
Lactobacillus acidophilus is an important member of the Lactobacillus family, a Gram-positive non-spore-forming bacterium with a streptomorphic or globular form and an optimal growth temperature of 37-42°C and an optimal pH of 6.8. Lactobacillus acidophilus was first isolated from human feces by North Carolina State University in the 1970s.
Lactobacillus acidophilus is an important member of the Lactobacillus family, a Gram-positive non-spore-forming bacterium with a streptomorphic or globular form and an optimal growth temperature of 37-42°C and an optimal pH of 6.8. Lactobacillus acidophilus was first isolated from human feces by North Carolina State University in the 1970s. It is the only strain of Lactobacillus acidophilus that has been genetically sequenced and annotated. Lactobacillus…
The use of restriction enzymes to characterize DNA has been popular since the 1970s. Today, this technique remains one of the easiest and fastest ways to evaluate DNA sequences. As with most laboratory reagents, restriction endonuclease can be fickle. Whether you are simply digesting a plasmid, or performing a complex cloning or screening procedure, there are several key factors to consider.
The use of restriction enzymes to characterize DNA has been popular since the 1970s. Today, this technique remains one of the easiest and fastest ways to evaluate DNA sequences. As with most laboratory reagents, restriction endonuclease can be fickle. Whether you are simply digesting a plasmid, or performing a complex cloning or screening procedure, there are several key factors to consider.   Corr…
Thioredoxin reductase (TrxR) is similar in activity to glutathione reductase (GR), catalyzing the reduction of GSSG to GSH, and is one of the key enzymes of the glutathione redox cycle.
Thioredoxin reductase (TrxR) is similar in activity to glutathione reductase (GR), catalyzing the reduction of GSSG to GSH, and is one of the key enzymes of the glutathione redox cycle.   TrxR is a dimeric flavoproteinase, a member of the pyridine nucleotide disulfide reductase family, widely expressed in cells of all levels of organisms from prokaryotes to humans. The three isozymes are named thioredoxin R1 (TrxR1) (cytoplasmic type), TrxR2 (mitochondrial type) and an isozyme TrxR3 (TGR) expressed mainly in the testis due to their different distribution regions. Cytoplasmic TrxR1 was the first to be di…
MicroRNAs (miRNAs) are non-coding RNAs containing 18-25 nucleotides encoded by endogenous genes and have the ability to regulate gene expression at the post-transcriptional level by repressing mRNA or promoting mRNA degradation. Typically, genes encoding miRNAs are more conserved in species that are very closely related, but they are sometimes homologous in species that are very distantly related.
What is microRNA? MicroRNAs (miRNAs) are non-coding RNAs containing 18-25 nucleotides encoded by endogenous genes and have the ability to regulate gene expression at the post-transcriptional level by repressing mRNA or promoting mRNA degradation. Typically, genes encoding miRNAs are more conserved in species that are very closely related, but they are sometimes homologous in species that are very…
Gene sequencing is a type of genomic testing technology. PCR, fluorescence in situ hybridization (FISH) and microarray technologies are mainly used to investigate the presence or absence of specific fragment sequences through known genes, which focuses on the detection of known mutations. Gene sequencing technology, on the other hand, involves measuring the nucleotides in the gene sequence one by one, focusing on obtaining the whole or target genome sequence. Gene sequencing currently has mainly one Sanger sequencing, next generation sequencing (NGS), long read sequencing (single-molecule real-time sequencing) and so on. The most widely used one is NGS.
What is gene sequencing? Gene sequencing is a type of genomic testing technology. PCR, fluorescence in situ hybridization (FISH) and microa…
The Massachusetts Life Science industry continues to grow at an exceptional rate, and in this article, we’ve rounded up ten of the top Pharmaceutical and Biotechnology companies in Massachusetts in 2022.
Massachusetts is home to one of the world’s leading Life Science hubs. In 2020, more than 89,000 individuals were employed by Massachusetts-based Life Science companies, representing a growth of over 67% in the last decade. The state is also widely regarded as the top biopharma cluster in the USA; thanks to its leading health systems, world-leading universities, state government support and robust venture capital pipeline. The Massachusetts Life Science industry continues to grow at an exceptional rate, and in this article, we’ve rounded up ten of the top Pharmaceutical and Biotechnology co…
The pharmaceutical industry is ever-evolving and will continue to grow, providing room for people with exceptional skills to find themselves a seat in the pharmaceutical world. In this article, we’ve put together 8 exceptional skills you need to possess to stand out amongst other applicants competing for the same positions you want.
The pharmaceutical industry is ever-evolving and will continue to grow, providing room for people with exceptional skills to find themselves a seat in the pharmaceutical world. In this article, we’ve put together 8 exceptional skills you need to possess to stand out amongst other applicants competing for the same positions you want. Take a Soft Skills Assessment Now! 1. Project planning: A company’s growth depends on the level of projects they execute. You need…
The leading CDMO in peptides and oligonucleotides manufacturing, Bachem, has started building a new future for oligonucleotides: solving the industry’s main challenges around capacity, sustainability and cost-effectiveness. Emerging as a new treatment option in rare and orphan disease areas, oligonucleotide therapeutics have matured into a drug class with a broad indication spectrum.
The leading CDMO in peptides and oligonucleotides manufacturing, Bachem, has started building a new future for oligonucleotides: solving the industry’s main challenges around capacity, sustainability and cost-effectiveness. Emerging as a new treatment option in rare and orphan disease areas, oligonucleotide therapeutics have matured into a drug class with a broad indication spectrum. The promise of oligonucleot…
24/7 Medical Billing Services help Physicians improve their practice’s revenue and efficiency by 30% by reducing their operational cost up to 40%. and streamline their medical billing process to operate effortlessly.
Medical billing for mental health services is more complicated than in other areas of healthcare due to the types of services, time, scope, and restraints placed on mental health treatments. For instance, if a patient visits a doctor for a routine check-up, they will almost certainly go through a standard series of tests and exams. This typically includes measuring the patient’s height and weight, taking their blood pressure, listening to their heart, and possibly drawing blood. These exams, for the most part, are standardized across all patients, take the same amount of time,…
24/7 Medical Billing Services help Physicians improve their practice’s revenue and efficiency by 30% by reducing their operational cost up to 40%. and streamline their medical billing process to operate effortlessly.
Navigating the insurance claim can be challenging for mental health practitioners, mainly if you are into individual or small facility practice. While most large medical facilities have an entire dedicated department trained in researching, submitting, and following up on the billing and the claims, you might be ‘winging it. It is because mental health billing is more complex and complicated than other medical billing. In fact, there is a lack of uniformity in the billing process. In most medical practices, standardized tests and services are performed. However, in me…
In this article, we’ve put together a list of the best Life Sciences organisations to work for in the UK, using the official rankings given by The Great Place to Work Institute in 2022…
In this article, we’ve put together a list of the best Life Sciences organisations to work for in the UK, using the official rankings given by The Great Place to Work Institute in 2022… Small Workplaces (20-50 Employees) i-Pharm Consulting Ltd i-Pharm provides talent solutions for the global Life Sciences sector and ranked 21st in this category. 100% of employees surveyed said there was a real ‘family’ or ‘team’ feeling at the organisation, with 99% also agreeing that management trusts people to do a good job without watching over their shoulders. Synergy Vision Synergy Vision is an award-winning medical com…
The potential of truly digital, data-driven product labeling in life sciences is huge, allowing companies to tailor and update their information more readily, unencumbered by space restrictions or print/production line deadlines. But what will it take for today’s discrete, local pilot projects to evolve into something more permanent and transformational for patients and healthcare professionals?
At Amplexor BE THE EXPERT 2022, Tris Nockles of Navitas, assessed the latest developments, the emerging challenges that need to be resolved, and what’s needed now to maintain and build momentum. Although digital labeling is widely available today across the globe through regulatory agency, trade association and company websites, this is largely in the form of static, unstructured content presented a…
Medical CRM can help healthcare organizations better understand and serve their patients, reconnect with ‘lost’ patients, and attract new ones. Additionally, it can automate some of the important workflows, provide an easy and secure data exchange environment, and relieve staff from routine tasks, giving them more time to care for patients and grow professionally. High-quality healthcare CRM is a complex system requiring time and budget to be implemented and extra time on organizing user training sessions. However, given the benefits mentioned in this article, it is worth the investment. To take the most advantage of this investment, it should be approached with a clear vision of the organization’s needs and goals.
Healthcare organizations are dedicated to providing excellent care for th…
Reboarding is the process of reintroducing employees to the workplace after they have been away for an extended period of leave, or after an organisation has experienced significant change. The goal of reboarding is to reassimilate employees back into their roles and the company culture of the organisation, whilst providing updates on new business goals, policies, and procedures.
Reboarding is the process of reintroducing employees to the workplace after they have been away for an extended period of leave, or after an organisation has experienced significant change. The goal of reboarding is to reassimilate employees back into their roles and the company culture of the organisation, whilst providing updates on new business goals, policies, and procedures. Unlike onboarding which generally p…
It is a well-known fact that without procurement, most businesses would not be able to operate. Reliable procurement management allows for projects and processes to be completed successfully, ensuring that items or services are provided on time, and at the right prices.
It is a well-known fact that without procurement, most businesses would not be able to operate. Reliable procurement management allows for projects and processes to be completed successfully, ensuring that items or services are provided on time, and at the right prices. Procurement can be a complex process, involving negotiation, building relationships and guaranteeing the timely delivery of potentially lifesaving products and services as is the case with healthcare procurement, which introduces additional challenges and req…
EMA’s latest shift in its IDMP implementation guidance has been well documented. At the coal face, it’s causing all kinds of confusion as pharma companies try to figure out what they should do now. At Amplexor Life Sciences’ BE THE EXPERT 2022, K2 Consulting’s Kelly Hnat drew on her ‘insider’ knowledge as an active participant in the EMA SPOR Task Force and member of the EMA PMS Process Focus Group, to provide some welcome clarity.
As most Regulatory teams know well, EMA has made some last-minute adjustments to its EU IDMP implementation plan, meaning that the Digital Application Dataset Integration Project (DADI) interface rather than FHIR will serve as the means for making data submissions - at least initially - once these become mandatory just under a year from now. To many, the move may…
Exports of MedTech products represent eight per cent of Ireland’s total merchandise exports, making Ireland the second largest exporter of medical technology in Europe, according to IDA Ireland. Investment in research and development (R&D) has positioned Ireland as a world leader in MedTech innovation. Here Dave Walsha, sales manager at small DC motor supplier EMS, explores how Ireland’s MedTech industry has made cutting-edge advances, with the support of micromotors.
Driving advances in the Irish MedTech industry  ~ Motors facilitate research and development in MedTech ~   Exports of MedTech products represent eight per cent of Ireland’s total merchandise exports, making Ireland the second largest exporter of medical technology in Europe, according to IDA Ireland. Investment in…