Articles
Discover how Clinion's Electronic Trial Master File (eTMF) optimizes clinical trial management with secure, efficient, and compliant document handling
Ensure faster trials, regulatory compliance, and real-time oversight with Clinion's innovative eTMF software. In the dynamic world of clinical research, efficient management of data and documents is crucial. Clinion's Electronic Trial Master File (eTMF) simplifies this process by providing a centralized platform for storing, organizing, and tracking all your clinical trial essentials. Key Benefits:Rapid Deployment: Start quickly with pre-built models and a configurable structure, reducing setup time to weeks. Intuitive Interface: Clinion's eTMF utilizes industry-standard DIA TMF Reference Models for a user-friendly experience, allowing for ef…
Ensure faster trials, regulatory compliance, and real-time oversight with Clinion's innovative eTMF software. In the dynamic world of clinical research, efficient management of data and documents is crucial. Clinion's Electronic Trial Master File (eTMF) simplifies this process by providing a centralized platform for storing, organizing, and tracking all your clinical trial essentials. Key Benefits:Rapid Deployment: Start quickly with pre-built models and a configurable structure, reducing setup time to weeks. Intuitive Interface: Clinion's eTMF utilizes industry-standard DIA TMF Reference Models for a user-friendly experience, allowing for ef…
Microneedle patches for the eyes and lips are small, adhesive patches that are infused with microneedles made of dissolvable materials such as hyaluronic acid or collagen.
In recent years, microneedle patches have emerged as a revolutionary technology in the beauty and skincare industry. These patches are designed to deliver active ingredients directly into the skin, providing targeted treatments for a variety of concerns. One area where microneedle patches have shown significant promise is in the treatment of the delicate skin around the eyes and lips. In this article, we will explore the latest innovations in microneedle eye and lip patch technologies, including advancements in manufacturing processes and delivery methods. Microneedle Eye and Lip Patch Microneedle patches for the eyes and…
In recent years, microneedle patches have emerged as a revolutionary technology in the beauty and skincare industry. These patches are designed to deliver active ingredients directly into the skin, providing targeted treatments for a variety of concerns. One area where microneedle patches have shown significant promise is in the treatment of the delicate skin around the eyes and lips. In this article, we will explore the latest innovations in microneedle eye and lip patch technologies, including advancements in manufacturing processes and delivery methods. Microneedle Eye and Lip Patch Microneedle patches for the eyes and…
The field of pharmaceuticals has seen rapid advancements in drug delivery technologies in recent years, one of which is long-lasting controlled-release microspheres technology.
The field of pharmaceuticals has seen rapid advancements in drug delivery technologies in recent years, one of which is long-lasting controlled-release microspheres technology. This technology involves the use of microscopic particles to deliver drugs in a controlled and sustained manner over an extended period of time. By encapsulating drugs within these microspheres, pharmaceutical companies are able to improve patient compliance, reduce dosing frequency, and enhance therapeutic outcomes. In this article, we will explore the benefits and applications of long-lasting controlled-release microspheres technology. Long-…
The field of pharmaceuticals has seen rapid advancements in drug delivery technologies in recent years, one of which is long-lasting controlled-release microspheres technology. This technology involves the use of microscopic particles to deliver drugs in a controlled and sustained manner over an extended period of time. By encapsulating drugs within these microspheres, pharmaceutical companies are able to improve patient compliance, reduce dosing frequency, and enhance therapeutic outcomes. In this article, we will explore the benefits and applications of long-lasting controlled-release microspheres technology. Long-…
PEG is soluble in organic solvents and water has excellent physicochemical and physiological properties, and is non-toxic, non-antigenic, and non-immunogenic. PEG is biocompatible and exhibits low protein and platelet adsorption in vivo as well as low cellular adherence, which are features that have led to a wide range of applications in biomedical fields.
Polymers play an important role in the biomedical field, and polyethylene glycol (PEG) and its derivatives are among the multifunctional polymers that have attracted much attention. PEG is a synthetic macromolecule with a linear structure consisting of glycol units (-CH2CH2O-) repeatedly linked. Its unique properties give PEG a wide range of applications. PEG is soluble in organic solvents and water has excellent physicochemical and physi…
Polymers play an important role in the biomedical field, and polyethylene glycol (PEG) and its derivatives are among the multifunctional polymers that have attracted much attention. PEG is a synthetic macromolecule with a linear structure consisting of glycol units (-CH2CH2O-) repeatedly linked. Its unique properties give PEG a wide range of applications. PEG is soluble in organic solvents and water has excellent physicochemical and physi…
26-Jul-2024
We’ve examined some of the most reviewed ATS on the market to bring you 10 of the top platforms of the year. These not only boast advanced features that cater to the changing dynamics of work, but also stand out for their innovative approaches to candidate engagement, seamless integration with HR ecosystems, adoption of AI and emerging technologies, and portfolios of complete solutions.
In 2024, Applicant Tracking Systems (ATS) continue to be the linchpin of a successful recruitment strategy, offering a blend of technological prowess and user-friendly interfaces to streamline the hiring process. The talent acquisition landscape is brimming with hundreds of HR and recruitment platforms all claiming to be the ultimate solution for anyone hiring top talent. But which ones are truly the most ef…
In 2024, Applicant Tracking Systems (ATS) continue to be the linchpin of a successful recruitment strategy, offering a blend of technological prowess and user-friendly interfaces to streamline the hiring process. The talent acquisition landscape is brimming with hundreds of HR and recruitment platforms all claiming to be the ultimate solution for anyone hiring top talent. But which ones are truly the most ef…
In the latest instalment of our Diversity, Equity & Inclusion Leadership series, we spoke to Ankit Mahadevia, MD, Founder and Chair of Spero Therapeutics, and author of Quiet Leader, Loud Results. Ankit talks about the value of cultural diversity, authenticity and trust, drawing on his sixteen years' experience creating and leading Life Science companies.
In the latest instalment of our Diversity, Equity & Inclusion Leadership series, we spoke to Ankit Mahadevia, MD, Founder and Chair of Spero Therapeutics, and author of Quiet Leader, Loud Results[1]. Ankit talks about the value of cultural diversity, authenticity and trust, drawing on his sixteen years' experience creating and leading Life Science companies. Coulter Partners: Please share your personal journey. Ankit Mahadevia: I'm th…
In the latest instalment of our Diversity, Equity & Inclusion Leadership series, we spoke to Ankit Mahadevia, MD, Founder and Chair of Spero Therapeutics, and author of Quiet Leader, Loud Results[1]. Ankit talks about the value of cultural diversity, authenticity and trust, drawing on his sixteen years' experience creating and leading Life Science companies. Coulter Partners: Please share your personal journey. Ankit Mahadevia: I'm th…
Lipids, a broad group of naturally occurring molecules, continue to play a significant role in various chemical processes. The analysis and characterization of lipids are critical steps in achieving effective chemical practices in several industries, including the chemical industry. Lipids can function as bio-active compounds in pharmaceuticals, ingredients in cosmetic products, and additives in biofuel production. Their diverse group of fats, oils, sterols, waxes, and other related compounds, provide a key resource for the chemical industry.
The chemical industry applies lipid analysis and characterization in creating specialty chemicals and polymers. Lipids can serve as raw materials in polymer chemistry. For instance, lipid-based monomers can be polymerized to produce high-value pla…
The chemical industry applies lipid analysis and characterization in creating specialty chemicals and polymers. Lipids can serve as raw materials in polymer chemistry. For instance, lipid-based monomers can be polymerized to produce high-value pla…
SN38-BSA is a bioconjugate product that is effectively revolutionizing the field of drug delivery. This article focuses on understanding its makeup and how bioconjugation is instrumental in its function and efficacy.
To begin with, SN38-BSA is composed of SN38, a potent anti-cancer drug, and BSA or Bovine Serum Albumin. SN38 is the active metabolite of the prodrug irinotecan, commonly used in chemotherapy. It's known for its high potency against cancer cells but has limitations in terms of bioavailability and solubility. BSA, on the other hand, is a protein derived from cows that has found extensive uses in biochemistry, including as a carrier protein for drugs. Bioconjugate chemistry is the chemical bonding of two biomolecules, enabling them to create hybrid molecules with new…
To begin with, SN38-BSA is composed of SN38, a potent anti-cancer drug, and BSA or Bovine Serum Albumin. SN38 is the active metabolite of the prodrug irinotecan, commonly used in chemotherapy. It's known for its high potency against cancer cells but has limitations in terms of bioavailability and solubility. BSA, on the other hand, is a protein derived from cows that has found extensive uses in biochemistry, including as a carrier protein for drugs. Bioconjugate chemistry is the chemical bonding of two biomolecules, enabling them to create hybrid molecules with new…
The fast-tracking landscape of contemporary gene therapy demands continuous advances in AAV (Adeno-associated virus) formulation development and the enhancement of cGMP (Current Good Manufacturing Practice) capacity. Together, these transformations are essential in producing safe and effective gene therapies for patients.
AAV Formulation Development: A Primary Focus In the field of gene therapy, AAV formulation development has gained significant focus. AAV vectors are used as delivery vehicles or "vectors" to administer therapeutic genes into patient's cells. This therapeutic gene, once inside the cell, generates a functional protein to correct or counter the effects of the disease-causing genetic mutation, providing a basis for curing several genetic diseases. The AAV's natur…
AAV Formulation Development: A Primary Focus In the field of gene therapy, AAV formulation development has gained significant focus. AAV vectors are used as delivery vehicles or "vectors" to administer therapeutic genes into patient's cells. This therapeutic gene, once inside the cell, generates a functional protein to correct or counter the effects of the disease-causing genetic mutation, providing a basis for curing several genetic diseases. The AAV's natur…
Mycotoxins and GMP fermentation are two key components to consider in today's food and beverage industry. With the increasing demand for high-quality and safe food products around the globe, it's important to understand the significance of these aspects in the production process.
Mycotoxins are toxic secondary metabolites produced by certain fungi. They can contaminate a wide range of commodities, from grain to dried fruits, spices, coffee, and cocoa. They represent a genuine health risk for both humans and animals, causing various diseases referred to as mycotoxicoses. Certain mycotoxins are carcinogenic, immune-suppressing, neurotoxic, or cause damage to organs like the liver. Hence, reducing and controlling mycotoxin levels in food products is of utmost importance. One possible wa…
Mycotoxins are toxic secondary metabolites produced by certain fungi. They can contaminate a wide range of commodities, from grain to dried fruits, spices, coffee, and cocoa. They represent a genuine health risk for both humans and animals, causing various diseases referred to as mycotoxicoses. Certain mycotoxins are carcinogenic, immune-suppressing, neurotoxic, or cause damage to organs like the liver. Hence, reducing and controlling mycotoxin levels in food products is of utmost importance. One possible wa…
07-Jun-2024
Explore the comprehensive guide to Whole Slide Imaging scanners, covering benefits, applications, and technology. Read the blog to know more.
Whole Slide Imaging: Whole slide imaging, commonly known as virtual microscopy, revolutionizes the way pathology specimens are analyzed by digitizing entire tissue slides for comprehensive examination. This technology involves scanning various whole slides digitally in high resolution, stitching together images derived from each field of view across the complete microscopy slide using specialized software. The result is a single digital image file that can be stored safely for archiving and documentation, benefiting the consulting and teaching industries. This cutting-edge technology allows pathologists to view high-resolution images of entire t…
Whole Slide Imaging: Whole slide imaging, commonly known as virtual microscopy, revolutionizes the way pathology specimens are analyzed by digitizing entire tissue slides for comprehensive examination. This technology involves scanning various whole slides digitally in high resolution, stitching together images derived from each field of view across the complete microscopy slide using specialized software. The result is a single digital image file that can be stored safely for archiving and documentation, benefiting the consulting and teaching industries. This cutting-edge technology allows pathologists to view high-resolution images of entire t…
Traditionally, copper-catalyzed azide-alkyne cycloaddition (CuAAC) has been the cornerstone of click chemistry, but concerns about cytotoxicity and metal contamination have sparked increasing interest in copper-free alternatives.
Click chemistry has revolutionized the field of bioconjugation, offering a robust and versatile approach for linking biomolecules, such as proteins, peptides, nucleic acids, and carbohydrates, to create novel materials and probes. Traditionally, copper-catalyzed azide-alkyne cycloaddition (CuAAC) has been the cornerstone of click chemistry, but concerns about cytotoxicity and metal contamination have sparked increasing interest in copper-free alternatives. This article explores the diverse applications of copper-free click chemistry in biomedical research, hig…
Click chemistry has revolutionized the field of bioconjugation, offering a robust and versatile approach for linking biomolecules, such as proteins, peptides, nucleic acids, and carbohydrates, to create novel materials and probes. Traditionally, copper-catalyzed azide-alkyne cycloaddition (CuAAC) has been the cornerstone of click chemistry, but concerns about cytotoxicity and metal contamination have sparked increasing interest in copper-free alternatives. This article explores the diverse applications of copper-free click chemistry in biomedical research, hig…
Medical devices encompass simple devices such as tongue depressors, bandages, and syringes to imaging devices (ultrasound and CT scanners), implantable devices (pacemakers), and medical equipment. The emergence and technological advancements in of data analytics, artificial intelligence (AI), and increased internet connectivity and accessibility has led to the widespread use of Software as a Medical Device (SaMD) in diseases prevention, diagnosis, and treatment.
Medical devices encompass simple devices such as tongue depressors, bandages, and syringes to imaging devices (ultrasound and CT scanners), implantable devices (pacemakers), and medical equipment. The emergence and technological advancements in of data analytics, artificial intelligence (AI), and increased internet connectivity and…
Medical devices encompass simple devices such as tongue depressors, bandages, and syringes to imaging devices (ultrasound and CT scanners), implantable devices (pacemakers), and medical equipment. The emergence and technological advancements in of data analytics, artificial intelligence (AI), and increased internet connectivity and…
It would be possible to put a stop to counterfeit medicines. However, simple controls are often still lacking. That's why researchers want to help drug detectives.
It would be possible to put a stop to counterfeit medicines. However, simple controls are often still lacking. That's why researchers want to help drug detectives. In 2015, health officials in the northern region of the Democratic Republic of the Congo stated that they had seen unexplained symptoms in hundreds of children, including convulsions, vertigo, and an erect posture. An emergency team was dispatched by Médecins sans Frontières (Doctors Without Borders) in response to a possible meningitis outbreak. Nevertheless, none of the patients have meningitis infections discovered by the investigators. The children's urine samples…
It would be possible to put a stop to counterfeit medicines. However, simple controls are often still lacking. That's why researchers want to help drug detectives. In 2015, health officials in the northern region of the Democratic Republic of the Congo stated that they had seen unexplained symptoms in hundreds of children, including convulsions, vertigo, and an erect posture. An emergency team was dispatched by Médecins sans Frontières (Doctors Without Borders) in response to a possible meningitis outbreak. Nevertheless, none of the patients have meningitis infections discovered by the investigators. The children's urine samples…
19-Jul-2024
A Chemistry, Manufacturing, and Controls (CMC) Specialist plays a crucial role in the pharmaceutical and biotechnology industries by ensuring that all aspects of the product development process related to chemistry, manufacturing, and controls meet regulatory standards and guidelines.
A Chemistry, Manufacturing, and Controls (CMC) Specialist plays a crucial role in the pharmaceutical and biotechnology industries by ensuring that all aspects of the product development process related to chemistry, manufacturing, and controls meet regulatory standards and guidelines. The primary function of a CMC Specialist is to oversee and guide the development, manufacturing, and testing processes of drugs or biologics to ensure product quality and compliance with regulatory requirements. This involves a d…
A Chemistry, Manufacturing, and Controls (CMC) Specialist plays a crucial role in the pharmaceutical and biotechnology industries by ensuring that all aspects of the product development process related to chemistry, manufacturing, and controls meet regulatory standards and guidelines. The primary function of a CMC Specialist is to oversee and guide the development, manufacturing, and testing processes of drugs or biologics to ensure product quality and compliance with regulatory requirements. This involves a d…
28-Jun-2024
As AI continues to evolve and integrate into various fields, the life sciences industry has begun leveraging this transformational technology to revolutionise regulatory affairs. Given the complexity and volume of regulatory requirements that companies must comply with, AI offers a promising solution to streamline processes and enhance accuracy.
As AI continues to evolve and integrate into various fields, the life sciences industry has begun leveraging this transformational technology to revolutionise regulatory affairs. Given the complexity and volume of regulatory requirements that companies must comply with, AI offers a promising solution to streamline processes and enhance accuracy. In this article, we delve into how AI is currently used within regulatory affairs in the life sciences, a…
As AI continues to evolve and integrate into various fields, the life sciences industry has begun leveraging this transformational technology to revolutionise regulatory affairs. Given the complexity and volume of regulatory requirements that companies must comply with, AI offers a promising solution to streamline processes and enhance accuracy. In this article, we delve into how AI is currently used within regulatory affairs in the life sciences, a…
Regulatory affairs professionals play a pivotal role in ensuring that pharmaceuticals, biologics, medical devices, and other life science products comply with all the relevant regulations. Their work is crucial to bringing safe and effective products to market and safeguarding public health. For those aspiring to venture into this field, understanding the top skills required is a vital first step.
Regulatory affairs professionals play a pivotal role in ensuring that pharmaceuticals, biologics, medical devices, and other life science products comply with all the relevant regulations. Their work is crucial to bringing safe and effective products to market and safeguarding public health. For those aspiring to venture into this field, understanding the top skills required is a vital first step.…
Regulatory affairs professionals play a pivotal role in ensuring that pharmaceuticals, biologics, medical devices, and other life science products comply with all the relevant regulations. Their work is crucial to bringing safe and effective products to market and safeguarding public health. For those aspiring to venture into this field, understanding the top skills required is a vital first step.…
09-May-2024
Polyethylene glycol can be used as antistatic agent and softener in cosmetics, pharmaceuticals, chemical fibers, rubber, plastics, papermaking, paints, electroplating, pesticides, metal processing and food. It has a wide range of applications in processing and other industries.
What is Polyethylene Glycol? Polyethylene glycol is a high molecular polymer with the chemical formula HO(CH2CH2O)nH. It is non-irritating, has good water solubility, and has good compatibility with many organic components. It has excellent lubricity, moisturizing, dispersion and adhesion. It can be used as antistatic agent and softener in cosmetics, pharmaceuticals, chemical fibers, rubber, plastics, papermaking, paints, electroplating, pesticides, metal processing and food. It has a wide range of applications…
What is Polyethylene Glycol? Polyethylene glycol is a high molecular polymer with the chemical formula HO(CH2CH2O)nH. It is non-irritating, has good water solubility, and has good compatibility with many organic components. It has excellent lubricity, moisturizing, dispersion and adhesion. It can be used as antistatic agent and softener in cosmetics, pharmaceuticals, chemical fibers, rubber, plastics, papermaking, paints, electroplating, pesticides, metal processing and food. It has a wide range of applications…
In the intricate landscape of the life sciences, the function of regulatory affairs stands as a linchpin, ensuring not only the seamless introduction of innovative medical solutions to the market but also their compliance with stringent legal and ethical standards. This realm of expertise, pivotal to the pharmaceutical, biotechnology, and broader life sciences industries, serves as the bridge between groundbreaking scientific advancements and their delivery to the global marketplace.
In the intricate landscape of the life sciences, the function of regulatory affairs stands as a linchpin, ensuring not only the seamless introduction of innovative medical solutions to the market but also their compliance with stringent legal and ethical standards. This realm of expertise, pivotal to the pharma…
In the intricate landscape of the life sciences, the function of regulatory affairs stands as a linchpin, ensuring not only the seamless introduction of innovative medical solutions to the market but also their compliance with stringent legal and ethical standards. This realm of expertise, pivotal to the pharma…
In today’s competitive clinical research landscape, seamless EDC-CTMS integration is not simply a convenience; it’s a strategic imperative
Clinical trials are complex endeavours that rely on meticulous data collection, efficient communication, and rigorous oversight. Two critical software systems underpin these needs: Electronic Data Capture (EDC) and Clinical Trial Management Systems (CTMS). This post explores why seamless integration between EDC and CTMS is paramount for effective trial management. What are EDC and CTMS? EDC (Electronic Data Capture): Imagine a digital filing cabinet for clinical trial data. EDC systems streamline participant data collection, ensuring accuracy and regulatory compliance. CTMS (Clinical Trial Management System): Think of CTMS system as t…
Clinical trials are complex endeavours that rely on meticulous data collection, efficient communication, and rigorous oversight. Two critical software systems underpin these needs: Electronic Data Capture (EDC) and Clinical Trial Management Systems (CTMS). This post explores why seamless integration between EDC and CTMS is paramount for effective trial management. What are EDC and CTMS? EDC (Electronic Data Capture): Imagine a digital filing cabinet for clinical trial data. EDC systems streamline participant data collection, ensuring accuracy and regulatory compliance. CTMS (Clinical Trial Management System): Think of CTMS system as t…
