Articles
What is Multiple System Atrophy and the Role of Therapeutics Multiple System Atrophy (MSA) is a progressive, rare neurodegenerative disorder adversely affecting the autonomic nervous system, movement, balance, coordination, and various bodily functions. Patients experience tremor, parkinsonian symptoms, cerebellar dysfunction, autonomic dysregulation (blood pressure, bladder control), and rapidly declining ability to perfor…
Research nurses play a pivotal role in bridging clinical care with scientific discovery, offering registered nurses (RNs) a rewarding alternative to traditional nursing. Their work supports the development of new treatments and enhances patient outcomes by conducting clinical trials and ensuring data integrity. Step-by-Step Guide to Becoming a Research Nurse 1. Build Clinical Experience:Begin with at least two years of hands-on nursing, ideally in high-impact areas like oncology, cardiology, or infectious diseases. 2. Develop Key Research Skills:Critical thinking, protocol adherence, data collection, and patient recruitmen…
The UK is at a pivotal moment in its digital journey. With more than £40 billion of fresh commitments from global technology leaders like Google, Microsoft, Nvidia, Salesforce and OpenAI, the country has earned a mandate to prove that it can convert tech investment into meaningful, sustainable transformation, according to leading UK CIO and BCS Fellow, Richard Corbridge. Richard Corbridge commented: “The next phase of UK technology growth depends not only on AI algorithms and software, but also on the infrastructure, skills, and trust frameworks that enable them to thrive. Energy resilience, advanced connectivity, and ethical governance will determine…
The production or refinement of pharmaceutical products often involves dispersing dusty, sticky or fine powders into liquids. When using conventional technology, this often leads to problems - for example, when agglomerated powders are not completely wetted. This is precisely where modern vacuum dispersing systems come in. Pharmaceutical products manufactured on the basis of powders or refined by powders include gels, ointments and suspensions, or tablet coatings. For these products, many di…
The hype surrounding medical AI often conjures images of powerful algorithms operating out of the clusters of a remote datacenter, but in practice, building clinically-viable technology is far more grounded. For too long, AI followed a linear path: tech firms gathered data, built algorithms, and forced them into clinical workflows. This “black box” approach led to a high rate of failure. Models were often brittle, non-compliant, and could not handle the messiness of real-world patient data. They struggled with fragmented records, nuanced longitudinal histories, or the subjectivity in radiology reports. Today’s bottleneck isn’t compute but clinical validity and regulatory readin…
In oncology, progress is often measured in small increments - a few additional months of survival, a slight improvement in quality of life, a percentage point gain in remission rates. While these steps are vital, they reflect an industry norm that focuses overwhelmingly on average patient outcomes. But hidden within the data are remarkable outliers: patients who, against all statistical odds, live far longer and better than expected. These “exceptional survivors” are not anomalies to be brushed aside; they are windows into the biology of resilience. Studying them deeply could reveal the mechanisms that transform certain cancers…
Pharmacovigilance (PV) as the cornerstone of drug safety, committed to safeguarding patient health by systematically monitoring, analyzing, and mitigating the risks associated with therapeutic products from pre-clinic stages through post-market oversight.As the innovation pipeline delivers a broader range of therapies, and as global clinical trials and ever-broader regulatory expectations…
What Counts as a Human Biological Specimen? Human biol…
Nutrigenomics, the study of how our genes interact with diet, is emerging as one of the most promising areas in personalized health. Genetic variations can influence how we metabolize nutrients, respond to supplements, and manage risks for chronic conditions. Understanding these patterns opens new opportunities for preventative care, optimized wellness strategies, and more targeted i…
The healthcare landscape is undergoing a profound transformation, and at its heart lies an often overlooked, yet absolutely critical, figure: the caregiver. Our recent "Agility: Hype to Hope to Health" event brought this reality into sharp focus during our panel, "The Rise of the Caregiver." It was a privilege to moderate a discussion with such inspiring women – Dr. Robyn Roth, Radiologist and Founder of The Boobie D…
A successful design and development process must balance exploration with structure, enabling teams to build high-quality products efficiently while adapting to change along the way. Yet, while the traditional design process may comprise four to five defined phases, Hurdle believes there is more to consider from the outset. Elements such as business analysis, capability planning, budgetary controls, capabil…
PharmiWeb Q&A - Romain Clement Sept 2025 1. Let’s start with the big picture — what inspired the founding of ArcaScience, and what core mission drives the company today? ArcaScience has its roots in a very personal journey. Years ago, I was diagnosed with a form of brain cancer and came face-to-face with how hard it is to design treatments truly adapted to individual patients. After my recovery, I bec…
The Role of Analytical Method Development in CRDMO Success Why Analytics Is a Pillar of Pharmaceutical Development In today’s pharmaceutical environment, where compliance and speed-to-market are paramount, analytical method development and validation play a foun…
The United States Food and Drug Administration’s (FDA’s) Accelerated Approval (AA) pathway, initially established in 1992 during…
As populations age across the globe, heal…
The Urgent Need for Change Women’s Health isn’t a niche issue. It concerns the health of half the population. And yet, the gender gap in healthcare remains overlooked. Women’s Health issues have historically been under-researched, marginalised, and underserved. This systemic neglect has led to disparities in diagnosis, treatment, and overall health outcomes for women. Addressing these gaps is not just a matter of equality, it is a matter of equity and scientific necessity. The Male Default in Medicine On the face of it, it seems obvious that men and women are biologically different, an…
Orthobiologics are biologically based therapies that support the body’s natural ability to heal musculoskeletal injuries. Derived from substances naturally found in the human body, they are increasingly used in orthopedics to accelerate recovery, reduce pain, and enhance surgical outcomes. With applications ranging from sports injuries to spinal fusion, orthobiologics are transforming how clinicians approach bone, tendon, ligament, and cartilage repair. What Are Orthobiologics? Orthobiologics use cells, growth factors, and biomaterials to promote healing at the…
3D bioprinting is redefining the boundaries of medical science, offering new possibilities in tissue engineering, regenerative medicine, and personalised healthcare. By using bio-inks composed of living cells, growth factors, and biomaterials, researchers can now print tissue-like structures that closely resemble the complexity of human organs. Unlike traditional 3D printing, which relies on plastics or metals, 3D bioprinting creates biological constructs layer by layer. The process typically begins with imaging and computer-aided design to create a digital blue…
The Rise of Investigator-Initiated Trials: A CRO’s Guide to Enabling Innovation Investigator-initiated trials (IITs) have progressively shifted from specialized academic projec…
Have you ever stopped to think about how a new medication gets from a scientist lab to your local pharmacy shelf? It is not just a guess or a hope it is a journey driven by the incredible power of data every medical breakthrough from a groundbreaking cancer treatment to a simple new vaccine is the result of painstaking and methodical work known as clinical research this field is all about asking the right questions and finding reliable answers that can change lives if you are fascinated by the science behind medicine or ar…