Articles

Centred Solutions Sales and Marketing Director, Louise Laban, gives her view on the current consultation into hub and spoke dispensing and questions some of the information included in the associated impact assessment.
“The second long awaited consultation on proposed changes to UK legislation to allow all community pharmacies to access hub and spoke dispensing is finally underway. Six years on from the original consultation, there remains speculation within the pharmacy market that the proposals may allow larger chains with automated hubs to charge smaller chains and independent pharmacies for “prescription assembly services” leading to an erosion of profits that cannot be recouped by any amount of patient facing services. Unfortunately the impact assessment into hub and spoke published by…

Historically, the way patients have been treated for diseases has been centred around our understanding of a dominant version of a disease as it occurs in the average human. The ailment is identified, a treatment path is offered, and drugs are prescribed. The effectiveness of this treatment, however, can vary due to a range of factors.
Historically, the way patients have been treated for diseases has been centred around our understanding of a dominant version of a disease as it occurs in the average human. The ailment is identified, a treatment path is offered, and drugs are prescribed. The effectiveness of this treatment, however, can vary due to a range of factors. The patient might have a particular variation of a disease, or a conflicting condition, or their biological makeup means cert…

A successful hit identification campaign relies on the use of a high-quality, diverse library of potential compounds to be screened, but also on capitalizing on other complementary techniques, such as structure-based virtual screening (SBVS) and fragment-based screening.
The major preclinical phases of peptide drug discovery encompass initial target identification and validation, hit identification, high throughput screening, lead optimization, etc. Among them, hit identification is one of the most critical steps in identifying peptides that can interact with well-validated targets.   Hit identification (HI) follows the process of target validation, in which the compound screening assays are developed. The main goal of the HI process is to apply the most suitable hit finding approaches…

Our work demands us to be mentally alert. There’s not much cruise control or autopilot in our industry. As a result, we need to be even more aware of self care and balance, to avoid burnout
Our work demands us to be mentally alert. There’s not much cruise control or autopilot in our industry. As a result, we need to be even more aware of self care and balance, to avoid burnout That's why it's important to cultivate a positive and flexible way of looking at things, and to keep your energy levels high. As a bonus, when you’re happy and focused, you can deliver more value and support to those around you In this article, we’ll share tips and ideas on how to build and maintain personal resilience. And how to develop the necessary behaviour to become an attractive candidate when seeking new roles…

“Australian companies with real ambition, realizing they could access the best talent anywhere on the globe, became very open to hiring executives in the US and Europe who could work remotely” Michael Huberts, Executive Director at Coulter Partners, provides an Australian perspective on Executive Search and Leadership Consulting in the Life Sciences, Health and Tech sectors. He explores the impact of the global Covid pandemic, the challenges of shrinking talent pools, government initiatives and investments, leadership diversity, digital health, and current trends.
“Australian companies with real ambition, realizing they could access the best talent anywhere on the globe, became very open to hiring executives in the US and Europe who could work remotely” Michael Huberts, Executive Dire…

Without a firm grip on data quality, life sciences companies will continue to be caught out by audits, missed registrations, or project disruption. As data becomes more important than documents, Amplexor’s Agnes Cwienczek provides practical starting points towards ensuring data quality, integrity, currency and completeness.
A comprehensive, approved master data source is increasingly vital to support a whole range of activities, whether submission and compliance related, or supporting internal analytics and management reporting. Without complete confidence in a defined quality, integrity, currency and completeness of data, however, there are two main risks to the business functions. One is that they will fall foul of the authorities, providing inaccurate or out-of-date information, and as a…

Clinical research is a process of testing the safety and efficacy of drugs and other medical products. It is done by qualified professionals who are responsible for the design, conduct, analysis, and reporting of clinical trials.
What is Clinical Research? Clinical research is a process of testing the safety and efficacy of drugs and other medical products. It is done by qualified professionals who are responsible for the design, conduct, analysis, and reporting of clinical trials. Clinical research is a process that ensures the safety and efficacy of drugs and other medical products. Clinical research professionals are responsible for designing, conducting, analyzing, and reporting clinical trials that test these products. Pharmacovigilance Courses in Pune. What is the Scope of Clinical Re…

First Impressions can be crucial to a great job interview! Improve you chances of landing that job, read some tips.
If you are like most job seekers, then your first REAL impression with a company is at an interview. The first thing you should do before an interview is make sure you're fully prepared. Careful preparation can help ensure that you get the job, and a few simple preparations can help set the tone for your interview. If possible, prepare in advance. Read up on the company's culture, mission and values to see if they align with your personal goals and personality. You don't want to go into an interview without having a solid understanding of the company, but it's also important not to overthink things. If you know what to expect at the interview, then you'll be able to relax and…

Laboratories are fast-paced, efficient work areas that require accurate data and confidence in your equipment, including your sample labels. A lost or damaged label can throw a lab's work into chaos. Losing this invaluable data means unknown variables now exist, such as sample contents, expiration, and impact on any other lab elements. That is why damaged labels will result in destroyed samples and lost work.
Laboratories are fast-paced, efficient work areas that require accurate data and confidence in your equipment, including your sample labels. A lost or damaged label can throw a lab's work into chaos. Losing this invaluable data means unknown variables now exist, such as sample contents, expiration, and impact on any other lab elements. That is why damaged labels will result in destroye…

Australia’s Life Science industry is booming, with 240,000+ people employed across more than 165 ASX-listed companies, with a total market capitalisation close to $300 billion. As the industry continues to thrive, the demand for skilled workers is only increasing, creating new opportunities not only for Australian citizens, but also for overseas workers looking to relocate.
Australia’s Life Science industry is booming, with 240,000+ people employed across more than 165 ASX-listed companies, with a total market capitalisation close to $300 billion. As the industry continues to thrive, the demand for skilled workers is only increasing, creating new opportunities not only for Australian citizens, but also for overseas workers looking to relocate. In this article, we’ve outlined 10 reasons to r…

SolasCure, a Cambridge-based biotech company developing revolutionary wound-cleaning technology, has seen its first trial patient receive treatment.
SolasCure, a Cambridge-based biotech company developing revolutionary wound-cleaning technology, has seen its first trial patient receive treatment.   Leveraging biomimicry and evidence-based medicine, the pioneering biologics company is developing its first investigational product, Aurase Wound Gel, a hydrogel containing an enzyme cloned from medical maggots, which aims to accelerate wound cleaning and support healthcare professionals treating patients with chronic wounds.   A chronic venous leg ulcer patient attending one of the research clinics involved in SolasCure's CLEANVLU trial has become the first in the world to receive the…

The rise of a more patient-centric, value-based healthcare environment gives the pharmaceutical industry a chance to find a new role and take a new seat at the table, says Gérard Klop of Vintura Consultancy.
The party’s over for traditional models of healthcare delivery. As populations continue to age and develop comorbidities, all players in the healthcare sector need to plan a more holistic approach to healthcare that involves issues such as wellness, pre-emptive interventions, and earlier targeting and tracking. Although daunting, this also gives the pharma industry an opportunity to establish a new role for itself. The major players are well aware that the days of simply supplying pills are over. Pharmaceutical organisations need to become more deeply embedded in delivering and monitori…

Pharmaceutical excipients can be classified into natural, semi-synthetic and fully synthetic compounds according to their sources.
Pharmaceutical excipients refer to the substances used in the production and formulation of medicines. They perform multiple functions in pharmaceutical preparations and are likely to affect the quality, safety and effectiveness of drugs. Pharmaceutical excipients can be classified into natural, semi-synthetic and fully synthetic compounds according to their sources. And based on their use, excipients can be divided into diluents, binders, disintegrants, lubricants, glidants and anti-caking agents, wetting agents and solubilizers. Among all varieties of excipients, how to select the most appropriate ones for a specific drug formulation project? The guidelines be…

The European Medicines Agency (EMA) has announced that the UNICOM’s DADI (Digital Application Dataset Integration) project will now be used for the implementation of regulatory data submissions. Amplexor’s Renato Rjavec looks at what this entails for pharma companies.
A more data-driven way of managing regulated product data, based on agreed standards, is the future of pharma. But the EMA’s decision means that for now, regulatory teams will have to manually manage data in two repositories – both information populated via DADI web forms, and the fuller data sets held within their own internal RIM systems. Nevertheless, although the announcement was a disappointment to some, leveraging the parallel DADI project relieves pressure on the pharma industry. DADI, which has been running in parallel…

Errors sometimes occur during drug development, but if pharma companies apply only a temporary solution to the problem, they risk repeating the same mistakes. Helen Lowe at Arriello outlines a best-practice approach that ensures the errors of the past are not repeated.
For companies to improve their performance, they have to understand their failures. But deep understanding requires more than just making a bit more effort – it needs a change of mindset where failures are not seen as problems but as opportunities for improvement. Establishing a Corrective Action Preventive Action (CAPA) programme benefits a company in many different ways. A well-designed CAPA programme can enhance and improve a company’s relationships with its clients and vendors, at the same time as cutting costs and reduci…

As The Great Resignation continues across the Life Science industry, now is the time for employers to reassess the working environments they offer and adapt these to the changing needs of workers post-pandemic. One way to understand what is and isn’t working well within your organisation is to arrange stay interviews with your employees.
As The Great Resignation continues across the Life Science industry, now is the time for employers to reassess the working environments they offer and adapt these to the changing needs of workers post-pandemic. One way to understand what is and isn’t working well within your organisation is to arrange stay interviews with your employees. These are conversations between an employee and their direct manager about what they like about their role, what issues t…

Since the peptide library provides a powerful tool for drug development, protein-protein interactions, and other biochemical as well as pharmaceutical applications, the total peptide library becomes a productive tool as it enjoys higher stability because of the special structure of the peptide bond. Additionally, its construction cycle is relatively short compared with traditional peptide library construction technologies, accelerating the development of peptides drugs.
Peptides with low molecular weight have been known to be less allergenic and the diverse physiological roles of peptides make them suitable candidates for the development of therapeutic agents. Peptide drugs are widely used in the prevention, diagnosis, and treatment of diseases such as cancer, diabetes, and AIDS. However, t…

Peptide plays a key role in basic biochemical and physiological processes, and it is essential to many aspects of biomedical research, especially when the pharmaceutical industry continues to apply new drug candidates in the biological field. Therefore, rapid, efficient, and reliable methodology for the chemical synthesis of peptide drugs is of utmost interest in chemical biology research.
Peptide plays a key role in basic biochemical and physiological processes, and it is essential to many aspects of biomedical research, especially when the pharmaceutical industry continues to apply new drug candidates in the biological field. Therefore, rapid, efficient, and reliable methodology for the chemical synthesis of peptide drugs is of utmost interest in chemical biology research.   In gener…

TrakCel was the first provider of integrated cellular orchestration solutions for the precise management, control and tracking of cell and gene therapy (CGT) products. It was established in 2012 by a group of co-founders with a background in temperature-controlled supply chain management services to the biotechnology industry. They were the first to identify the challenges of managing complex supply chains associated with both clinical and commercial cell and gene therapies.
TrakCel was the first provider of integrated cellular orchestration solutions for the precise management, control and tracking of cell and gene therapy (CGT) products. It was established in 2012 by a group of co-founders with a background in temperature-controlled supply chain management services to the biotechnology in…

Protein structure analysis is one of the core contents of protein engineering. It mainly collects a large amount of protein molecular structure information in order to establish a database of the relationship between structure and function, thereby laying a foundation for theoretical research on the relationship between protein structure and function. Protein structure analysis is of great significance for the strategic consideration and specific approach selection of protein engineering aiming at designing and constructing novel proteins.
Protein structure analysis is one of the core contents of protein engineering. It mainly collects a large amount of protein molecular structure information in order to establish a database of the relationship between structure and function, thereby laying…