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Peroxidase, usually derived from horseradish, is a common enzyme used in clinical testing reagents. It is widely used not only in several biochemical assays but also in immunoassay (ELISA) kits. As a key component of the color development system of several kits, peroxidase has an important impact on the quality of the kits.
Peroxidase, usually derived from horseradish, is a common enzyme used in clinical testing reagents. It is widely used not only in several biochemical assays but also in immunoassay (ELISA) kits. As a key component of the color development system of several kits, peroxidase has an important impact on the quality of the kits.   Horseradish peroxidase (HRP) is the most commonly used enzyme because of its high activity, stability, small molecular weight and easy prepara…

Penicillinase is an enzyme that acts on the β-lactam ring of penicillin to convert penicillin into penicillic acid, which has no antibacterial activity. A variety of penicillin-resistant bacteria can produce this enzyme, such as the penicillin-resistant strains of Staphylococcusaureus and the penicillin-resistant strains of Bacillus cereus. This enzyme is a medical enzyme suitable for the treatment of allergic reactions to penicillin in general, and can also be used as an adjunctive treatment for patients with anaphylaxis or severe penicillin allergic reactions. Bacillus cereus can be used as a production strain of this enzyme.
Penicillinase is an enzyme that acts on the β-lactam ring of penicillin to convert penicillin into penicillic acid, which has no antibacterial activity. A variety of…

With the UK’s Clinical Research industry booming, and with the current job market becoming increasingly candidate-driven, 2022 is an excellent time to be considering a career move within or into Clinical Research. Following on from our previous article outlining 10 Clinical Research career paths, we’ve used Indeed’s Salary Guide to put together this list of the average base salary in the UK for these 13 common Clinical Research roles.
Clinical Research in England alone is worth approximately £2.7 billion a year. In March 2021, the UK government published its vision aimed at propelling the UK Clinical Research industry into the future. 5 key themes underpin this vision: Streamlined, efficient and innovative research Clinical research embedded in the NHS Patient-centred research Research ena…

At Amplexor BE THE EXPERT 2022, Remco Munnik of Iperion - a Deloitte business, took the example of product labeling to highlight the overlap between documents and data, and how internationally-agreed standards can contribute to a more streamlined approach to (and beyond) regulatory information management – from early development through to pharmacovigilance.
Although the value of developing more data-driven processes is now widely recognized, many life sciences organizations today still routinely create critical documents and product labeling from scratch. This involves capturing and applying the same information repeatedly, yet often in different formats and using inconsistent terminology. At Amplexor BE THE EXPERT 2022, Remco Munnik of Iperion - a Deloitte business, took the example of pr…

Whilst Pharma job promotions undoubtedly bring with them numerous benefits both personally and professionally, politely declining a promotion is valid if the new role just isn’t going to work for you. In this article, we outline 8 reasons why you may want to turn down a job promotion; addressing some of the main concerns when it comes to making changes in your career, and laying out advice on what you could do before making the decision to say no.
After falling 7.4% in 2020, promotions among professional workers in the US shot up by 9% in 2021, and this increase is also being recognised in job markets across the globe. Whilst many Pharma and Life Science employees are still fighting for the promotions they missed out on during the pandemic, these opportunities aren’t a priority for everyone…

At Amplexor Life Sciences’ BE THE EXPERT 2022 conference, Dr. Thierry Dietrich of pharm@dviser, discussed the different levels of cloud use and the best approaches to ensuring compliance in each case, as regulators pay closer attention to cloud-based data management.
As pharmaceutical companies become more confident and ambitious in their use of the cloud to host, run and source applications, more recently extending the model to regulated applications, important considerations arise - particularly around associated systems validation and data governance. At Amplexor Life Sciences' BE THE EXPERT 2022 conference, Dr. Thierry Dietrich of pharm@dviser, discussed the different levels of cloud use and the best approaches to ensuring compliance in each case, as regulators pay closer attention to c…

With over 15 years of experience across their senior leadership team, The Global Life Science Hub provides functional services and consulting with a solid mission to accelerate, strengthen and enhance global clinical trials.
Introducing GLS With over 15 years of experience across their senior leadership team, The Global Life Science Hub provides functional services and consulting with a solid mission to accelerate, strengthen and enhance global clinical trials. Financially backed by specialist head-hunting firm AL Solutions, they are primed to continue the growth and development of the Clinical Development and Biometrics sectors with the support of AL2S3 to effectively expand their functional services globally. The Global Life Science Hub strives to ensure that all their clinical research c…

“I like the excitement of not knowing what’s going to happen and I think I thrive on it.” For the first interview in our Human Strategy Series,  the team recently spoke with Dr Jackie Ameri, CEO of Pancryos, who benefited from our Leadership Assessment service as part of the partnership between Coulter Partners and the BioInnovation Institute (BII). Jackie discusses her early career, her decision to join the BII and highlights the benefits of being part of the BII Creation House Program.
“I like the excitement of not knowing what’s going to happen and I think I thrive on it.” For the first interview in its Human Strategy Series,  the Coulter Partners team recently spoke with Dr Jackie Ameri, CEO of Pancryos, who benefited from our Leadership Assessment service as part of the partner…

In the seventh interview in its Diversity, Equity & Inclusion Leadership series, Coulter Partners spoke to Tomoko Adachi, General Manager of Global HR and HR Business Partner for the Cardiac and Vascular Company at Terumo Corporation. Tomoko shares her insights in good D, E & I practice from her recent experience in medtech and compares this with what she has seen in the tech world, drawing on her 29-year tenure with Sony before Terumo.
“… For us to drive innovation that addresses the diverse healthcare needs of our global society, we need a diverse team…” --- In the next interview in our Diversity, Equity & Inclusion Leadership series, we spoke to Tomoko Adachi, General Manager of Global HR and HR Business Partner for the Cardiac and Vascular Company at Terumo Corporation. Tomoko share…

Already experts in the area of ophthalmology, Santen decided to harness the potential of cell and gene therapies (CGTs) to address unmet needs and change the lives of patients living with inherited retinal disorders (IRDs).
Solving the leading cause of inherited blindness Already experts in the area of ophthalmology, Santen decided to harness the potential of cell and gene therapies (CGTs) to address unmet needs and change the lives of patients living with inherited retinal disorders (IRDs). The recently established Santen Cell & Gene is a global business unit that is dedicated to changing patient lives through transformative solutions. Founded in Japan over a century ago, Santen has been contributing to people’s eye health for the past 130 years and has expanded to cover over 60 count…

A 2021 Mercer survey reported that 87% of life science companies were planning to offer part-time remote working models in the future. In 2022, remote working opportunities across the industry are continuously rising, with companies such as IQVIA, Worldwide Clinical Trials and Syneos Health advertising homeworking roles across the globe. To make homeworking work for you, we’ve outlined 12 things you can do to optimise your work from home space.
A 2021 Mercer survey reported that 87% of life science companies were planning to offer part-time remote working models in the future. In 2022, remote working opportunities across the industry are continuously rising, with companies such as IQVIA, Worldwide Clinical Trials and Syneos Health advertising homeworking roles across the globe.   Whether y…

Human pulmonary cells, a mainstay of many medical research labs, have acquired new relevance in the era of COVID-19. As the SARS-CoV-2 virus causes serious complications most commonly in the lungs, human primary pulmonary cells have become increasingly important in the study of this coronavirus strain.
The human respiratory system is composed of a network of tissues and organs that enable the body to absorb oxygen from the air as well as expel carbon dioxide and other waste gasses. These functions are supported by a variety of cells that aid in promoting epithelial homeostasis, preventing alveolar collapse, facilitating the exchange of gasses between the blood and the tissues, and ensuring that the lungs adjust properly to low atmospheric pressure. Primary cells taken directly from the resp…

In short, different diseased PBMCs were used for a wide variety of immunology-based applications, including in vitro immunoassays, population characterization, sequencing studies, and biologic testing as above. However, in the application process, attention should be paid to the quality stability, ethical issues of traceability, whether the cells are fresh, the selection of appropriate cells for different studies, etc.
Brief Introduction to PBMCs Peripheral Blood Mononuclear Cells (PBMC), also called Human Mononuclear Cells from Peripheral Blood (HMNC-PB), are cells with a single, round nucleus that are collected from peripheral or circulating blood. These blood cells are a key component in the immune system to fight infections and disease, adapting to invaders. PBMCs resp…

The functions of MSCs mainly include differentiation capacity, immune regulation and antimicrobial properties. Differentiation capacity indicates the identity of MSCs stem cells and makes it become the basis for maintaining organ and tissue survival [16]. MSCs are also involved in immunomodulatory processes. MSCs can affect a variety of innate and specific immune cells and can produce a variety of immune factors. And the antibacterial ability of MSCs mainly comes from their ability to produce a variety of antibacterial peptides, which enables MSCs to have broad-spectrum antibacterial activity.
Introduction What are Stem Cells? Stem cells refer to undifferentiated or partially differentiated cells in multicellular organisms. Stem cells can replicate indefinitely and differentiate into differ…

It’s been a busy few years at PharmiWeb as we continue our growth on a global scale. After establishing ourselves as a leading Life Science job board, we have been focused on developing our entire range of Talent Acquisition solutions, introducing new features and resources to help our clients continue to locate and engage the best talent in the industry.
It’s been a busy few years at PharmiWeb as we continue our growth on a global scale. After establishing ourselves as a leading Life Science job board, we have been focused on developing our entire range of Talent Acquisition solutions, introducing new features and resources to help our clients continue to locate and engage the best talent in the industry. Here, we’ve rounded up some of our key milestones over the past few years, sharing in…

Whenever a foreign substance is introduced into the body, there will be a chance of rejection or having an adverse reaction. This reaction is the risk taken when trusting the pharmaceuticals that we have come to rely on for our wellness. We need these drugs, but sometimes other circumstances tell us otherwise.
Whenever a foreign substance is introduced into the body, there will be a chance of rejection or having an adverse reaction. This reaction is the risk taken when trusting the pharmaceuticals that we have come to rely on for our wellness. We need these drugs, but sometimes other circumstances tell us otherwise. What is an Adverse Drug Reaction? An Adverse Drug Reaction is also known as an ADR - the unwanted or uncomfortable effects of a drug. ADRs can also be dangerous to the one exper…

15 Pharma and Life Science events taking place in June 2022, including Pharmaceutical, Biotechnology, Clinical Research and Medical Devices events.
15 Pharma and Life Science events taking place in June 2022, including Pharmaceutical, Biotechnology, Clinical Research and Medical Devices events. 13th Edition Biologics Formulation Development and Drug Delivery Conference (June 1st-3rd) This industry-wide known marcus evans conference will gather experienced pharma industry scientists and academics to discuss key challenges around biologics drug development. International Congress of Micro-Immunotherapy (ICoMI) (June 2nd-4th) This virtual conference is open to researchers, healthcare and medical professionals looking for up-to-date knowledge and medical experience, new impulses for research an…

Having weathered a global pandemic and the war in Ukraine, the medical technology industry might be forgiven for believing – or at least hoping – that the worst may soon be over. A cost-of-living crisis should not, on the face of it, be something that would directly affect companies involved in the production of surgical equipment and medical technology, but risk lurks in the unlikeliest of corners.
Having weathered a global pandemic and the war in Ukraine, the medical technology industry might be forgiven for believing – or at least hoping – that the worst may soon be over. A cost-of-living crisis should not, on the face of it, be something that would directly affect companies involved in the production of surgical equipment and medical technology, but risk lurks in the unlikeliest of corn…

Burnout can cause people to make mistakes such as duplications, incorrect information, and late data entry causing incorrect decision-making. Being one of the most passionate and necessary industries, it is important that healthcare workers including nurses, doctors and clinicians are given the right amount of support. With this in mind, Hannah Wilkinson, Head of People & Culture at Radar Healthcare, shares five ways health tech companies can alleviate burnout across the workforce.
Around 400 staff are leaving the NHS every week due to the effects of stress, including burnout and PTSD, in the workplace.  Burnout can cause people to make mistakes such as duplications, incorrect information, and late data entry causing incorrect decision-making.  Being one of the most passionate and necessary…

Industries are continuously evolving, and the pharma industry is no exception. There are trends impacting the way we think about pharma, how pharma development is conducted, and the opportunities for pharma to make an impact on a societal level. Looking ahead, we can see a few trends that have emerged and that are gaining traction within the industry. This in turn influences how portfolio management is perceived and what it is expected to deliver.
Industries are continuously evolving, and the pharma industry is no exception. There are trends impacting the way we think about pharma, how pharma development is conducted, and the opportunities for pharma to make an impact on a societal level. Looking ahead, we can see a few trends that have emerged and that are gaining traction within the indus…