Articles
In this article, we’ve put together a list of the best Life Sciences organisations to work for in the UK, using the official rankings given by The Great Place to Work Institute in 2022…
In this article, we’ve put together a list of the best Life Sciences organisations to work for in the UK, using the official rankings given by The Great Place to Work Institute in 2022… Small Workplaces (20-50 Employees) i-Pharm Consulting Ltd i-Pharm provides talent solutions for the global Life Sciences sector and ranked 21st in this category. 100% of employees surveyed said there was a real ‘family’ or ‘team’ feeling at the organisation, with 99% also agreeing that management trusts people to do a good job without watching over their shoulders. Synergy Vision Synergy Vision is an award-winning medical com…
In this article, we’ve put together a list of the best Life Sciences organisations to work for in the UK, using the official rankings given by The Great Place to Work Institute in 2022… Small Workplaces (20-50 Employees) i-Pharm Consulting Ltd i-Pharm provides talent solutions for the global Life Sciences sector and ranked 21st in this category. 100% of employees surveyed said there was a real ‘family’ or ‘team’ feeling at the organisation, with 99% also agreeing that management trusts people to do a good job without watching over their shoulders. Synergy Vision Synergy Vision is an award-winning medical com…
The potential of truly digital, data-driven product labeling in life sciences is huge, allowing companies to tailor and update their information more readily, unencumbered by space restrictions or print/production line deadlines. But what will it take for today’s discrete, local pilot projects to evolve into something more permanent and transformational for patients and healthcare professionals?
At Amplexor BE THE EXPERT 2022, Tris Nockles of Navitas, assessed the latest developments, the emerging challenges that need to be resolved, and what’s needed now to maintain and build momentum. Although digital labeling is widely available today across the globe through regulatory agency, trade association and company websites, this is largely in the form of static, unstructured content presented a…
At Amplexor BE THE EXPERT 2022, Tris Nockles of Navitas, assessed the latest developments, the emerging challenges that need to be resolved, and what’s needed now to maintain and build momentum. Although digital labeling is widely available today across the globe through regulatory agency, trade association and company websites, this is largely in the form of static, unstructured content presented a…
12-Jul-2022
Medical CRM can help healthcare organizations better understand and serve their patients, reconnect with ‘lost’ patients, and attract new ones. Additionally, it can automate some of the important workflows, provide an easy and secure data exchange environment, and relieve staff from routine tasks, giving them more time to care for patients and grow professionally.
High-quality healthcare CRM is a complex system requiring time and budget to be implemented and extra time on organizing user training sessions. However, given the benefits mentioned in this article, it is worth the investment. To take the most advantage of this investment, it should be approached with a clear vision of the organization’s needs and goals.
Healthcare organizations are dedicated to providing excellent care for th…
Healthcare organizations are dedicated to providing excellent care for th…
Reboarding is the process of reintroducing employees to the workplace after they have been away for an extended period of leave, or after an organisation has experienced significant change. The goal of reboarding is to reassimilate employees back into their roles and the company culture of the organisation, whilst providing updates on new business goals, policies, and procedures.
Reboarding is the process of reintroducing employees to the workplace after they have been away for an extended period of leave, or after an organisation has experienced significant change. The goal of reboarding is to reassimilate employees back into their roles and the company culture of the organisation, whilst providing updates on new business goals, policies, and procedures. Unlike onboarding which generally p…
Reboarding is the process of reintroducing employees to the workplace after they have been away for an extended period of leave, or after an organisation has experienced significant change. The goal of reboarding is to reassimilate employees back into their roles and the company culture of the organisation, whilst providing updates on new business goals, policies, and procedures. Unlike onboarding which generally p…
It is a well-known fact that without procurement, most businesses would not be able to operate. Reliable procurement management allows for projects and processes to be completed successfully, ensuring that items or services are provided on time, and at the right prices.
It is a well-known fact that without procurement, most businesses would not be able to operate. Reliable procurement management allows for projects and processes to be completed successfully, ensuring that items or services are provided on time, and at the right prices. Procurement can be a complex process, involving negotiation, building relationships and guaranteeing the timely delivery of potentially lifesaving products and services as is the case with healthcare procurement, which introduces additional challenges and req…
It is a well-known fact that without procurement, most businesses would not be able to operate. Reliable procurement management allows for projects and processes to be completed successfully, ensuring that items or services are provided on time, and at the right prices. Procurement can be a complex process, involving negotiation, building relationships and guaranteeing the timely delivery of potentially lifesaving products and services as is the case with healthcare procurement, which introduces additional challenges and req…
07-Jul-2022
EMA’s latest shift in its IDMP implementation guidance has been well documented. At the coal face, it’s causing all kinds of confusion as pharma companies try to figure out what they should do now. At Amplexor Life Sciences’ BE THE EXPERT 2022, K2 Consulting’s Kelly Hnat drew on her ‘insider’ knowledge as an active participant in the EMA SPOR Task Force and member of the EMA PMS Process Focus Group, to provide some welcome clarity.
As most Regulatory teams know well, EMA has made some last-minute adjustments to its EU IDMP implementation plan, meaning that the Digital Application Dataset Integration Project (DADI) interface rather than FHIR will serve as the means for making data submissions - at least initially - once these become mandatory just under a year from now. To many, the move may…
As most Regulatory teams know well, EMA has made some last-minute adjustments to its EU IDMP implementation plan, meaning that the Digital Application Dataset Integration Project (DADI) interface rather than FHIR will serve as the means for making data submissions - at least initially - once these become mandatory just under a year from now. To many, the move may…
06-Jul-2022
Exports of MedTech products represent eight per cent of Ireland’s total merchandise exports, making Ireland the second largest exporter of medical technology in Europe, according to IDA Ireland. Investment in research and development (R&D) has positioned Ireland as a world leader in MedTech innovation. Here Dave Walsha, sales manager at small DC motor supplier EMS, explores how Ireland’s MedTech industry has made cutting-edge advances, with the support of micromotors.
Driving advances in the Irish MedTech industry ~ Motors facilitate research and development in MedTech ~ Exports of MedTech products represent eight per cent of Ireland’s total merchandise exports, making Ireland the second largest exporter of medical technology in Europe, according to IDA Ireland. Investment in…
Driving advances in the Irish MedTech industry ~ Motors facilitate research and development in MedTech ~ Exports of MedTech products represent eight per cent of Ireland’s total merchandise exports, making Ireland the second largest exporter of medical technology in Europe, according to IDA Ireland. Investment in…
12-Jul-2022
Medical CRM can help healthcare organizations better understand and serve their patients, reconnect with ‘lost’ patients, and attract new ones. Additionally, it can automate some of the important workflows, provide an easy and secure data exchange environment, and relieve staff from routine tasks, giving them more time to care for patients and grow professionally.
High-quality healthcare CRM is a complex system requiring time and budget to be implemented and extra time on organizing user training sessions. However, given the benefits mentioned in this article, it is worth the investment. To take the most advantage of this investment, it should be approached with a clear vision of the organization’s needs and goals.
Healthcare organizations are dedicated to providing excellent care for th…
Healthcare organizations are dedicated to providing excellent care for th…
For large- or small-scale fermentation, process optimization in some critical steps plays an important role in improving efficiency because it can directly affect the formation, concentration, and yield of a particular fermentation end product, thus affecting the overall economics.
However, the improvement of fermentation process is frequently associated with a lot of challenges: it's expensive, laborious, open-ended, and time-consuming. There are many aspects requiring attention from CDMOs to obtain better outcomes. The article below explores different well-known elements that are vital in the whole fermentation process. Upstream Process Optimization Upstream process optimization is used for microbial fermentation to enhance the strains' manufacturing efficiency and capac…
However, the improvement of fermentation process is frequently associated with a lot of challenges: it's expensive, laborious, open-ended, and time-consuming. There are many aspects requiring attention from CDMOs to obtain better outcomes. The article below explores different well-known elements that are vital in the whole fermentation process. Upstream Process Optimization Upstream process optimization is used for microbial fermentation to enhance the strains' manufacturing efficiency and capac…
It is an efficient way to regulate molecular function by applying specific chemical modifications on biological molecules. This article highlights the current heated pseudoUridine modification in RNA, which suggests new possibilities for novel drug or vaccine discovery.
An Introduction to PseudoUridines PseudoUridine (Ψ) is a post-transcriptional RNA modification that alters RNA-RNA and RNA-protein interactions and affects gene expression. PseudoUridine modification is also named "fifth base" since it is the earliest and most abundant RNA modification among the 170+ types of known RNA modifications. Messenger RNA pseudouridylation was recently discovered as a widespread and conserved phenomenon, but the mechanisms responsible for selective and regulated…
An Introduction to PseudoUridines PseudoUridine (Ψ) is a post-transcriptional RNA modification that alters RNA-RNA and RNA-protein interactions and affects gene expression. PseudoUridine modification is also named "fifth base" since it is the earliest and most abundant RNA modification among the 170+ types of known RNA modifications. Messenger RNA pseudouridylation was recently discovered as a widespread and conserved phenomenon, but the mechanisms responsible for selective and regulated…
04-Jul-2022
Many research institutes and pharmaceutical companies are now actively engaged in COVID-19 research and treatment development, which makes some supportive reagents, services, and consultations in high demand around the world.
This article briefly summarizes several relatively important solutions that can greatly facilitate COVID-19 research. COVID-19 mRNA Vaccine Development Support The global outbreak of COVID-19 in early 2020 caused a large amount of investment and research attention to developing preventive vaccines. Among the massive achievements made by using published genomes, mRNA vaccines against SARS-CoV-2 stand out because of their better performance in efficiency and cost-effectiveness. Currently, mRNA vaccine is publicly deemed as a very useful strategy in anti-…
This article briefly summarizes several relatively important solutions that can greatly facilitate COVID-19 research. COVID-19 mRNA Vaccine Development Support The global outbreak of COVID-19 in early 2020 caused a large amount of investment and research attention to developing preventive vaccines. Among the massive achievements made by using published genomes, mRNA vaccines against SARS-CoV-2 stand out because of their better performance in efficiency and cost-effectiveness. Currently, mRNA vaccine is publicly deemed as a very useful strategy in anti-…
Phytochemicals are natural compounds that have only been discovered so far and are natural food pigments. The human body is unable to produce them and must obtain them from food. Soy isoflavones in soybeans, lycopene in tomatoes, catechins in green tea, carotenoids in carrots, zeaxanthin, polyphenols, etc., are all phytochemicals.
What Are Phytochemicals? Phytochemicals are natural compounds that have only been discovered so far and are natural food pigments. The human body is unable to produce them and must obtain them from food. Soy isoflavones in soybeans, lycopene in tomatoes, catechins in green tea, carotenoids in carrots, zeaxanthin, polyphenols, etc., are all phytochemicals. Classification and Functions of Common Phytochemicals Flavonoids Species: Quercetin, brassin, catechin…
What Are Phytochemicals? Phytochemicals are natural compounds that have only been discovered so far and are natural food pigments. The human body is unable to produce them and must obtain them from food. Soy isoflavones in soybeans, lycopene in tomatoes, catechins in green tea, carotenoids in carrots, zeaxanthin, polyphenols, etc., are all phytochemicals. Classification and Functions of Common Phytochemicals Flavonoids Species: Quercetin, brassin, catechin…
05-Jul-2022
The functioning of biological systems is inextricably linked to protein-protein interactions, and important biological processes such as DNA synthesis, gene transcriptional activation, protein translation, modification and localization, and information transfer all involve the role of protein complexes.
Introduction to protein interactions The functioning of biological systems is inextricably linked to protein-protein interactions, and important biological processes such as DNA synthesis, gene transcriptional activation, protein translation, modification and localization, and information transfer all involve the role of protein complexes. Therefore, it is particularly important to discover and verify protein-nucleic acid and protein-protein interactions in living organisms. Various techniqu…
Introduction to protein interactions The functioning of biological systems is inextricably linked to protein-protein interactions, and important biological processes such as DNA synthesis, gene transcriptional activation, protein translation, modification and localization, and information transfer all involve the role of protein complexes. Therefore, it is particularly important to discover and verify protein-nucleic acid and protein-protein interactions in living organisms. Various techniqu…
04-Jul-2022
Ceramides are composed of sphingosine analogs and long-chain fatty acids bound by amide bonds, and are the most important of the sphingolipid compounds. Ceramide is synthesized and secreted by lamellar vesicles, which together with cholesterol (25%) and free fatty acids (15%) constitute the intercellular lipids (ceramide 50%) involved in maintaining the skin barrier function. It also has various physiological and pharmacological functions, such as regulation of cellular immunity, delaying aging, and antitumor.
Ceramides are composed of sphingosine analogs and long-chain fatty acids bound by amide bonds, and are the most important of the sphingolipid compounds. Ceramide is synthesized and secreted by lamellar vesicles, which together with cholesterol (25%) and free fatty acids (15%) constitu…
Ceramides are composed of sphingosine analogs and long-chain fatty acids bound by amide bonds, and are the most important of the sphingolipid compounds. Ceramide is synthesized and secreted by lamellar vesicles, which together with cholesterol (25%) and free fatty acids (15%) constitu…
Under ‘normal’ circumstances, citizens already hope to deal with the public sector in the same seamless and convenient way that they shop online for groceries. However, during large-scale crises – like, but not limited to the ongoing pandemic, rather than downsizing staff within public services, they are having to work harder than ever before.
In current times, businesses and citizens are seeking more reassurance and proactive support from the public sector than ever before, as they weather the remaining storm of COVID-19. In turn, those working in the public are dealing with a long list of challenges every single day to meet new needs and requirements. Under ‘normal’ circumstances, citizens already hope to deal with the public sector in the same seamless and convenient way that the…
In current times, businesses and citizens are seeking more reassurance and proactive support from the public sector than ever before, as they weather the remaining storm of COVID-19. In turn, those working in the public are dealing with a long list of challenges every single day to meet new needs and requirements. Under ‘normal’ circumstances, citizens already hope to deal with the public sector in the same seamless and convenient way that the…
Medicines are becoming ever more complex in response to growth in personalised treatments and the development of a wide range of therapeutics to address less common conditions or rare diseases
by Kelly Doering, Sr Director, Industry Marketing, Pharma, AspenTech Medicines are becoming ever more complex in response to growth in personalised treatments and the development of a wide range of therapeutics to address less common conditions or rare diseases. Examples of the latter include small molecules linked to large, perhaps conjugated to a chemotoxic agent for targeted cancer treatment; peptides linked to peptides; oligos linked to molecules that allow for better cell permeability; and lipid-encapsulated molecules that prevent degradation. But it is the market for more personalised medication…
by Kelly Doering, Sr Director, Industry Marketing, Pharma, AspenTech Medicines are becoming ever more complex in response to growth in personalised treatments and the development of a wide range of therapeutics to address less common conditions or rare diseases. Examples of the latter include small molecules linked to large, perhaps conjugated to a chemotoxic agent for targeted cancer treatment; peptides linked to peptides; oligos linked to molecules that allow for better cell permeability; and lipid-encapsulated molecules that prevent degradation. But it is the market for more personalised medication…
The pharmaceutical and biopharmaceutical industries have been seeing a trend towards single-use technologies. However, this new approach and the introduction and advance of personalized therapies are currently leading to massive supply-chain delays in terms of single-use consumables. Therefore, new solutions have to be found and companies have to think strategically and change up processes as soon as possible.
As there is an upward trend to single-use technologies, strategic thinking and the courage to change up processes are called for in the pharma industry. The pharmaceutical and biopharmaceutical industries are seeing a major shift to disposable technologies. However, this shift and the introduction and advance of personalized and allogeneic therapies are currently leading to massive su…
As there is an upward trend to single-use technologies, strategic thinking and the courage to change up processes are called for in the pharma industry. The pharmaceutical and biopharmaceutical industries are seeing a major shift to disposable technologies. However, this shift and the introduction and advance of personalized and allogeneic therapies are currently leading to massive su…
04-Jul-2022
Stable isotope-labeled peptides have also been widely used in (NMR) spectroscopy and mass spectrometry (MS) as well as reference materials for pharmacokinetic analysis and metabolite identification.
Peptides are organic compounds formed by the dehydration of amino acids and intermediate products of protein hydrolysis. Peptides have strong biological activity, which can regulate the functional activities of cells in living organisms, and play a variety of roles in medicine, cosmetics, food, and other fields. With the more and more extensive and in-depth applications of peptides, the demand for labeled and modified peptides is growing, and the quality requirement is also higher and higher. To obtain peptides with higher biological activity, fluorescent modification, isotop…
Peptides are organic compounds formed by the dehydration of amino acids and intermediate products of protein hydrolysis. Peptides have strong biological activity, which can regulate the functional activities of cells in living organisms, and play a variety of roles in medicine, cosmetics, food, and other fields. With the more and more extensive and in-depth applications of peptides, the demand for labeled and modified peptides is growing, and the quality requirement is also higher and higher. To obtain peptides with higher biological activity, fluorescent modification, isotop…
ADCs demonstrated great potential for the treatment of cancers, and simultaneously require unique supporting infrastructure to meet biopharmaceutical industry standards for safe, effective, and reliable manufacturing.
Antibody-drug conjugates (ADCs) are formed by covalent biochemical conjugation of monoclonal antibodies (mAb) with payload drugs through small molecular linkers. They are regarded as an emerging class of drugs designed for high-specificity targeting and destruction of cancer cells, since the specificity of mAb to tumor cells allows small-molecule drugs to target tumor tissues, effectively reducing the high toxicity of traditional small-molecule drugs and improving overall treatment efficiency. ADC manufacturing consists of multiple steps that can be divided in…
Antibody-drug conjugates (ADCs) are formed by covalent biochemical conjugation of monoclonal antibodies (mAb) with payload drugs through small molecular linkers. They are regarded as an emerging class of drugs designed for high-specificity targeting and destruction of cancer cells, since the specificity of mAb to tumor cells allows small-molecule drugs to target tumor tissues, effectively reducing the high toxicity of traditional small-molecule drugs and improving overall treatment efficiency. ADC manufacturing consists of multiple steps that can be divided in…
30-Jun-2022
The Covid pandemic has elevated the diagnostics industry to new heights of relevance and given it a place in the popular consciousness not previously seen.
The subsequent rise in global fuel prices and the economic impact of the war in Ukraine have also focused the minds of medical technology company bosses and health budget planners on the need to do more with fewer resources. All of these developments, coupled with greater use of artificial intelligence (AI) in medicine, means that technology has never been more important to the health of populations. This is particularly true of in vitro diagnostics – with the pandemic accelerating investment in infectious disease diagnoses to unprecedented levels – and with activity now spinning out to other areas. A market research study published this…
The subsequent rise in global fuel prices and the economic impact of the war in Ukraine have also focused the minds of medical technology company bosses and health budget planners on the need to do more with fewer resources. All of these developments, coupled with greater use of artificial intelligence (AI) in medicine, means that technology has never been more important to the health of populations. This is particularly true of in vitro diagnostics – with the pandemic accelerating investment in infectious disease diagnoses to unprecedented levels – and with activity now spinning out to other areas. A market research study published this…
